• The Journal of Natural Sciences
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• v.9 no.1
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• pp.1-7
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• 1997

Calcium/calmodulin-dependent protein kinase II (CaMK-II) is responsible for the phosphorylation of proteins involved in various cellular functions. Since the level of intracellular calcium ($Ca_2+$) oscillate during the cell cycle, it is expected that the activity of CaMK-II is also dependent on the cell cycle. The kinase activity in NIH3T3 cells which were arrested at or released from certain phase of the cell cycle was measured and compared to that in the normally growing asynchronous control cells to investigate whether the activity of this kinase is cell cycle-dependent. Cells were arrested at G0, G1, G1/S, G2/M and M phase, respectively by use of various drugs which do not have any effect on the kinase activity of CaMK-II at G0, G1, G1/s and G2/M phase was similar to that of the control cells, whereas lower at M. Calcium-independent activity of CaMK_II by autophosphorylation was higher at M and, thus, higher autonomy at M, which represented the physiologically relevant activity of CaMK-II. A similar pattern of activity change of the kinase was demonstrated during the cell cycle of synchronized cells which were released from G1 arrest. These results indicate that the activity of CaMK-11 is cell cycle-dependent and is activity during the mitosis.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 1998.05a
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• pp.321-326
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• 1998

본 논문에서는 정밀 제어와 온-라인 제어를 위하여 유전 알고리즘을 이용한 퍼지-신경망 제어기를 제안하였다. 제안된 제어기의 설계방법은 다음과 같은 3단계의 동조과정으로 구성한다. 1) 퍼지 제어기의 비퍼지화 연산을 신경망을 이용하여 함수근사화 시킨 후, 퍼지-신경망 제어기를 구성한다. 2) 플랜트에 적합한 퍼지 소속함수의 형태를 얻기 위해 유전 알고리즘을 이용하여 근사화된 퍼지 소속함수를 찾는다. 3) 근사화된 초기 퍼지 소속함수를 퍼지-신경망 제어기에 의해 적응학습으로 최적의 퍼지 소속함수를 얻고, 또한 플랜트의 파라미터 변동이나 외부환경의 변화에 대해 적응할 수 있도록 최적의 퍼지 소속함수를 추정한다. 제안된 제어기의 성능을 평가하기 위하여 DC 서보모터의 속도제어에 적용하였다.

• The Proceedings of the Korean Institute of Illuminating and Electrical Installation Engineers
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• v.8 no.3
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• pp.64-70
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• 1994

We propose a new method to deal with optimal auto-tuning of the PID controller which is used to process control in various fields. First of all, in this method, 1st order system which was modeled from the unit step response of the system is Pade-approximated, then initial values are determined by the Ziegler-Nichols method. Finally, we can find the parameters of PID controller so as to maximize the fuzzy criterion function which includes the maximum overshoot, damping ratio, rising time and settling time. The Proposed method also shows good adaptability for variations in characteristics and dead m e of the system.

• Science of Emotion and Sensibility
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• v.20 no.1
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• pp.67-74
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• 2017

The goal of this study is to present quantification method for empathy. The micro-movement technology (non-contact sensing method) was used to identify empathy level. Participants were first divided into two groups: Empathized and not empathized. Then, the upper body data of participants were collected utilizing web-cam when participants carried expression tasks. The data were analyzed and categorized into 0.5 Hz, 1 Hz, 3 Hz, 5 Hz, 15 Hz. The average movement, variation, and synchronization of the movement were then compared. The results showed a low average movement and variation in a group who empathized. Also, the participants, who empathized, synchronized their movement during the task. This indicates that the people concentrates with each other when empathy has been established and show different levels of movement. These findings suggest the possibility of empathy quantification using non-contact sensing method.

• The Transactions of the Korean Institute of Power Electronics
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• v.27 no.2
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• pp.157-164
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• 2022

This study proposes an enhanced quadruple-Active-Bridge (QAB) converter that can solve power coupling problems. By adopting a multiple winding transformer, the equivalent circuit of a conventional QAB converter has power couplings between arbitrary output ports. This coupling is an unintended power relationship that complicates the regulation of output voltage of the multiple ports. The proposed converter can carry out power decoupling by changing the arrangement of the coupling inductor. Power transfer equations for the proposed converter and its operating principles are analyzed in detail. The power coupling caused by the transformer's leakage inductance is verified by using a proposed coupling factor that presents the relationship between inductance ratio and coupling power. In addition, the decoupling power control performance of the proposed converter is verified by simulation and a 3 kW prototype converter.

• Journal of radiological science and technology
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• v.32 no.3
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• pp.299-306
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• 2009

Purpose : To compare radiation dose for coronary CT angiography (CTA) obtained with 6 examination protocols such as a retrospectively ECG gated helical scan, a prospectively ECG gated sequential scan, low kVp technique, and cardiac dose modulation technique. Materials and Methods : Coronary CTA was performed by using 6 current clinical protocols to evaluate effective dose and organ dose in primary beam area with anthropomorphic female phantom and glass dosimetric system in 64 channel multi-detector CT. After acquiring topograms of frontal and lateral projection with 80 kVp and 10 mA, main coronary scan was done with 0.35 sec tube rotation time, 40 mm collimation ($0.625\;mm{\times}64\;ea$), small scan field of view (32 cm diameter), 105 mm scan length. Heart beat rate of phantom was maintained 60 bpm in ECG gating. In constant mAs technique 120 kVp, 600 mA was used, and 100 kVp for low kVp technique. In a retrospectively ECG gated helical CT technique 0.22 pitch was used, peak mA (600 mA) was adopted in range of $40{\sim}80%$ of R-R interval and 120mA(80% reduction) in others with cardiac dose modulation. And 210 mAs was used without cardiac dose modulation. In a prospectively ECG gated sequential CT technique data were acquired at 75% R-R interval (middle diastolic phase in cardiac cycle), and 120 msec additional padding of the tube-on time was used. For effective dose calculation region specific conversion factor of dose length product in thorax was used, which was recommended by EUR 16262. Results : The mean effective dose for conventional coronary CTA without cardiac dose modulation in a retrospectively ECG gated helical scan was 17.8 mSv, and mean organ dose of heart was 103.8 mGy. With low kVp and cardiac dose modulation the mean effective dose showed 54.5% reduction, and heart dose showed 52.3% reduction, compared with that of conventional coronary CTA. And at the sequential scan(SnapShot pulse mode) under prospective ECG gating the mean effective dose was 4.9 mSv, this represents an 72.5% reduction compared with that of conventional coronary CTA. And heart dose was 33.8 mGy, this represents 67.4% reduction. In the sequential scan technique under prospective ECG gating with low kVp the mean effective dose was 3.0 mSv, this represents an 83.2% reduction compared with that of conventional coronary CTA. And heart dose was 17.7 mGy, this represents an 82.9% reduction. Conclusion : In coronary CTA at retrospectively ECG gated helical scan, cardiac dose modulation technique using low kVp reduced dose to 50% above compared with the conventional helical scan. And the prospectively ECG gated sequential scan offers substantially reduced dose compared with the traditional retrospectively ECG gated helical scan.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.48 no.3
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• pp.167-174
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• 2020

A study of flow characteristics of supersonic fluidic oscillators with shared feedback channel inside was carried out. Unsteady CFD analysis were performed and the numerical results were validated by comparison with the experimental ones observed for the same operation conditions. It was found that the mass flow between individual oscillators through the shared feedback channel directly influenced on the oscillating flow mechanism inside the oscillator, and finally on the synchronization of the jet oscillations. It was also observed that the oscillator with shared feedback channel provided higher pressure loss as well as higher oscillation frequency as compared to the single oscillator of the same geometric shape.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.7 no.5
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• pp.830-836
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• 2006

In this paper described an auto tuning neuro-fuzzy PID controller based neural network. The PID type controller has been widely used in industrial application due to its simply control structure, easy of design, and inexpensive cost. However, control performance of the PID type controller suffers greatly from high uncertainty and nonlinearity of the system, large disturbances and so on. In this paper will design to take advantage of neural network fuzzy theory and pid controller auto toning technique. The value of initial scaling factors of the proposed controller were determined on the basis of the conventional PID controller parameters tuning methods and then they were adjusted by using neural network control techniques. This controller simple structure and computational complexity are less, and also application is easy and performance is excellent in system that is strong and has nonlinearity to system dynamic behaviour change or disturbance. Finally, the proposed auto tuning neuro-fuzzy controller is applied to magnetic levitation. Simulation results demonstrated that the control performance of the proposed controller is better than that of the conventional controller.

• Sleep Medicine and Psychophysiology
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• v.4 no.1
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• pp.57-65
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• 1997

As jet lag of modern travel continues to spread, there has been an exponential growth in popular explanations of jet lag and recommendations for curing it. Some of this attention are misdirected, and many of those suggested solutions are misinformed. The author reviewed the basic science of jet lag and its practical outcome. The jet lag symptoms stemed from several factors, including high-altitude flying, lag effect, and sleep loss before departure and on the aircraft, especially during night flight. Jet lag has three major components; including external de synchronization, internal desynchronization, and sleep loss. Although external de synchronization is the major culprit, it is not at all uncommon for travelers to experience difficulty falling asleep or remaining asleep because of gastrointestinal distress, uncooperative bladders, or nagging headaches. Such unwanted intrusions most likely to reflect the general influence of internal desynchronization. From the free-running subjects, the data has revealed that sleep tendency, sleepiness, the spontaneous duration of sleep, and REM sleep propensity, each varied markedly with the endogenous circadian phase of the temperature cycle, despite the facts that the average period of the sleep-wake cycle is different from that of the temperature cycle under these conditions. However, whereas the first ocurrence of slow wave sleep is usually associated with a fall in temperature, the amount of SWS is determined primarily by the length of prior wakefulness and not by circadian phase. Another factor to be considered for flight in either direction is the amount of prior sleep loss or time awake. An increase in sleep loss or time awake would be expected to reduce initial sleep latency and enhance the amount of SWS. By combining what we now know about the circadian characteristics of sleep and homeostatic process, many of the diverse findings about sleep after transmeridian flight can be explained. The severity of jet lag is directly related to two major variables that determine the reaction of the circadian system to any transmeridian flight, eg., the direction of flight, and the number of time zones crossed. Remaining factor is individual differences in resynchmization. After a long flight, the circadian timing system and homeostatic process can combine with each other to produce a considerable reduction in well-being. The author suggested that by being exposed to local zeit-gebers and by being awake sufficient to get sleep until the night, sleep improves rapidly with resynchronization following time zone change.

• Proceedings of the Korean Society of Propulsion Engineers Conference
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• v.y2005m4
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• pp.291-298
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• 2005

Linear acoustic analysis has been performed to elucidate damping characteristics of acoustic cavities. Results have shown that resonant frequencies of acoustic cavity obtained by classical theoretic approach and present linear analysis are somewhat different from each other. This difference is due to the limitation of classical theory. To quantify the damping characteristics, acoustic impedance has been introduced and resultant absorption and conductance have been evaluated. Satisfactory agreement has been achieved with previous experiment. Finally the design procedure for optimal tuning of acoustic cavity has been established