• Title/Summary/Keyword: 비교 연구

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Effects of Anti-inflammation and Skin Barrier by Genistein Cyclodextrin Complex (제니스테인 Cyclodextrin 포접체의 항염 및 피부장벽에 미치는 영향)

  • Choi, Dong Jun;Cho, Uk Min;Choi, Da Hee;Hwang, Hyung Seo
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.44 no.2
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    • pp.171-181
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    • 2018
  • Genistein is one of the representative isoflavone compounds isolated from soybeans and has been studied very well for its anti-aging and anti-inflammatory activity through previous studies. However, although genistein exhibits high solubility in organic solvents, it shows low bioavaility due to the low water solubility. In this study, we compared directly the functional difference between genistein and genistein cyclodextrin complex which has the improved water solubility and stability by cell based assay. Cell cytotoxicity experiment were carried out on RAW264.7 with CCK-8 assay and cytotoxicity was appeared from $10{\mu}g/mL$, thereby maximum concentration was set to $10{\mu}g/mL$ in all condition. We discovered that genistein CD complex suppressed NO production and iNOS expression as concentration dependent manner in the condition of LPS rather than genistein. Also, we could understand that genistein CD complex was able to down-regulate mRNA expression of anti-inflammatory cytokines such as $IL1-{\alpha}$, $IL1-{\beta}$, IL-6, and $TNF-{\alpha}$ as concentration dependent manner in the presence of LPS. In addition, we verified that genistein CD complex increased TEER of HaCaT human keratinocyte cells as concentration dependent pattern and stimulated cell division and migration rather than genistein in cell migration assay. Thus, it is expected that it can be used as an effective cosmetic raw material for improving atopic dermatitis or skin barrier if clinical studies on skin regeneration and skin barrier of the genistein CD complex are carried out.

Comparison of quality characteristics between seasonal cultivar of salted-Kimchi cabbage (Brassica rapa L. ssp. Pekinesis) (계절별 절임배추의 품질 특성 비교)

  • Ku, Kyung Hyung;Choi, Eun Jeong;Jeong, Moon Cheol
    • Food Science and Preservation
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    • v.21 no.4
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    • pp.512-519
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    • 2014
  • This study was carried to investigate the physicochemical and microbiological characteristics of seasonal salted-Kimchi cabbage order to provide basic data for optimal salting and storage condition of seasonal Kimchi cabbage. Generally, fall season samples had slightly higher pH and acidity value than the other seasonal salted Kimchi cabbage. The soluble solids content of spring, summer, fall and winter samples were 5.95%, 6.18%, 6.29% and 7.76%, respectively. The salt content of all the seasonal salted Kimchi cabbage samples were insignificant. The number of microbial bacteria in the summer samples were generally much more significant than spring and winter samples. There was no significant difference in the color of seasonal salted Kimchi cabbage. As for the texture properties, the firmest samples in the surface rupture test were the spring samples (force: 4.92 kg), and the hardest samples in the puncture test were the summer samples (force: 11.71 kg). In the correlation analysis of the quality characteristics of seasonal samples, the soluble solids content and hardness of the seasonal salted Kimchi cabbage was significantly correlated at 1% significance level. Also, in the principal component analysis, F1 and F2 were shown to explain 27.28% and 35.59% of the total variance (62.87%), respectively. The hierarchical cluster analysis of the quality characteristics of seasonal samples, the samples were divided into three groups: spring cabbage group, summer cabbage group and fall and winter cabbage group.

Effects of different cooking methods on folate retention in selected mushrooms (다양한 조리법에 따른 버섯류의 엽산 리텐션)

  • Park, Su-Jin;Park, Sun-Hye;Chung, Heajung;Lee, Junsoo;Hyun, Taisun;Chun, Jiyeon
    • Food Science and Preservation
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    • v.24 no.8
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    • pp.1103-1112
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    • 2017
  • This study was performed to investigate the effects of different cooking methods (boiling, roasting, stir-frying, and deep-frying) on folate retention in 6 kinds of mushrooms (Beech-, button-, Juda's ear-, oak-, oyster-, and winter-mushrooms) frequently consumed in Korea. In order to assure reliability of analytical data, trienzyme extraction-L casei method was verified and analytical quality control was also evaluated. Folate contents of mushrooms varied by 6.04-64.82 g/100 g depending on the type of mushrooms. and were significantly affected by cooking methods. Depending on cooking methods, folate contents of mushrooms decreased by 22-48%, 2-31%, and 17-56% for Juda's ear-, oak- and oyster-mushrooms, respectively, while 17-90% of folate was increased in Beech mushroom. Overall, the largest weight loss was found in boiled mushrooms, but the lowest one in deep-fried samples. True folate retention rates considering processing factor were less than 100% for all cooked mushrooms except for Beech samples. Overall, folate loss was the largest by boiling with water but the smallest by deep-frying. Both accuracy and precision of trienzyme extraction-L-casei method were excellent based on a recovery close to 100% and coefficient variations less than 3%. Quality control chart of folate analysis (n=26) obtained during the entire study and an international proficiency test (z-score=-0.5) showed that trienzyme extraction-L casei method is reliable enough for production of national folate database.

Skin Whitening Effect of Ethyl Acetate Fraction of Adenophora triphylla var. japonica Sprout (잔대(Adenophora triphylla var. japonica)순 아세트산에틸 분획물의 피부 미백 효과)

  • Yoo, Seul Ki;Park, Seon Kyeong;Kang, Jin Yong;Kim, Jong Min;Park, Sang Hyun;Kwon, Bong Seok;Lee, Chang Jun;Kang, Jeong Eun;Park, Su Bin;Lee, Uk;Heo, Ho Jin
    • Korean Journal of Plant Resources
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    • v.30 no.4
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    • pp.352-363
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    • 2017
  • To investigate skin-whitening effect of Adenophora triphylla var. japonica sprout extract, antioxidant activity, inhibitory effect on tyrosinase and melanin synthesis in B16/F10 melanoma cell were examined. Total phenolic content (246.25 mg GAE/g) and total flavonoid content (303.94 mg RE/g) of ethyl acetate fraction from Adenophora triphylla sprout (EFAT) showed the highest contents than other fractions (n-hexane, chloroform and distilled water). Antioxidant activities of EFAT has been evaluated using ABTS, DPPH radical scavenging activities, FRAP and inhibitory effect of lipid peroxidation. EFAT showed excellent radical scavenging activity and inhibitory effect on MDA production. Inhibitory effect of tyrosinase as a major enzyme of melanin synthesis was also measured. In these results, EFAT showed higher inhibitory effect against L-DOPA (51.27%) than L-tyrosine. $IC_{50}$ value on ${\alpha}-glucosidase$ was $41.93{\mu}g/ml$. In B16/F10 melanoma cells, EFAT inhibited melanin synthesis at $200{\mu}g/ml$ concentration (about 42% decrease). Finally, main physiological compounds of EFAT were identified as a rutin and a chlorogenic acid using high performance liquid chromatography.

A study of mandibular positional changes by the stabilization splint in TMD patients (측두하악장애환자에서 교합안정장치가 하악골위치변화에 미치는 영향에 관한 연구)

  • Cheon, Hun;Park, Young-Guk;Chung, Kyu-Rhim
    • The korean journal of orthodontics
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    • v.30 no.4 s.81
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    • pp.491-507
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    • 2000
  • The purpose of this study was to investigate if there were a significant differences in mandibular position between cephalometric measurements from a centric occlusion tracing compared to those of a acquired centric relation by stabilization splint on malocclusion patient with TMD. 60 malocclusion patients, who had TMD and CO-CR discrepancy beyond normal range, were selected and subdivided into Class I, II, III by Angle's classification and also subdivided into clockwise, straight downward, and counterclockwise group by Jarabak's posterior facial height/anterior facial height ratio. Lateral cephaolmetric radiographs with the mandible in centric occlusion were taken and measured, and for each Patient the stabilization splint with mutually protected occlusal scheme was applied for minimum 3months. After each patient's CO-CR discrepancy was in normal range, lateral cephalometric radiographs were retaken and measured. The comparison of the difference between CO-CR cephalometric measurements in all sample, Class I, II, III groups, and Clockwise, Straight downward, Counterclockwise groups were studied. The finding of this study can be summarized as follows: 1 In all sample, the value of cephalometric measurements was significantly different between CO-CR. The mandible rotated to down and posterior position and the vertical change was greater than the horizontal change (overjet-1.3mm increase, overbite-1.9mm decrease). 2. In Class II malocclusion group, most of the mean difference value between CO-CR is higher than that of the other groups and more measurements was statically significant. 3. In clockwise and counterclockwise group, some of the mean difference value is higher than that of straight downward group and more measurements was statically significant. 4. There ware no measurements that explain centric relation measurements from the type of malocclusion, facial pattern and centric occlusion measurements. Henceforth, it is strongly recommended that stabilization splint therapy for orthodontic treatment on TMD patient should be excuted upon overall facial types prior to orthodontic diagnosis and treatment planning.

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A Six-Year Study of Relationship between Academic Performance in Dental Hygiene School and Performance on the Korean Dental Hygiene Licensing Examination at Yonsei University (Y-대학교 치위생학과 졸업생의 학교 성적과 국가시험 성적의 상관성)

  • Mun, So-Jung;Noh, Hie-Jin;Jeon, Hyun-Sun;Heo, Ji-Eun;Chung, Won-Gyun
    • Journal of dental hygiene science
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    • v.14 no.3
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    • pp.332-341
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    • 2014
  • This study was aimed to define the predicting factor account for the Korean Dental Hygienist Licensing Examination (KDHLE) by analyzing the academic grade score and the KDHLE score. The subjects included 185 graduates (2007, 2009, 2011~2014 graduates). The ratio of successful applicants of the subjects was 99.2%. The academic grade scores were calculated to grade point average, the KDHLE was scoring marks out of 300 (200 of written examination score and 100 of performance evaluation score) for correlation and regression analysis. The graduation grades and comprehensive examination scores correlated significantly with the KDHLE written examination scores (correlation coefficient=0.612), and KDHLE total score (correlation coefficient=0.258). First~third grade score and comprehensive examination scores correlated significantly with KDHLE total scores (p<0.05). Especially, there are the highest correlated between second comprehensive examination scores and KDHLE total scores (correlation coefficient=0.455), the last score in time sequence is the important factors account for the KDHLE total score. But there is no correlation between academic grade score and KDHLE performance evaluation scores, therefore it is necessary to study for determine the reason. The results of multiple linear regression analysis, second grade score and the average score of comprehensive examination were the main predicting factors account for the KDHLE total score, the explanatory power was 31.6%. Our results show that KDHLE total and written examination scores are predicted by the academic grade score reliably, but not the KDHLE performance evaluation scores. Further studies are needed to determine relationship between dental hygiene education and KDHLE.

Comparisons of Cardiovascular Disease Risk Factors and Sarcopenia-related Factors according to Physical Activity Levels in Basic Livelihood Security Recipients Elderly Women (기초생활보장수급 여성노인의 신체활동수준에 따른 심혈관질환 위험요인 및 근감소증 관련요인의 비교 분석)

  • Hwang, Eun-Jin;Hong, JeeYoung;Park, Joonkyu;Kim, Jeongeun;Kim, Sukwha;Kong, Hyoun-Joong
    • Journal of Digital Convergence
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    • v.11 no.10
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    • pp.507-516
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    • 2013
  • The purpose of this study is to identify physical activity levels of the basic livelihood security recipients elderly women, to investigate relation between cardiovascular disease risk factors and sacrcopenia based on the levels, and to develop physical activity programs for healthy life of the elderly. The subjects of this study were 134 old females with $71{\pm}6.67$ years old who used senior centers in K-gu. The authors used the International Physical Activity Questionnaire for investigating the physical activity levels of the elderly, measuring their physical activity levels for seven days on average and classifying them into two groups, the Low Physical Activity (n=77) and the Moderate Physical Activity (n=57) groups based on the levels. Blood pressure, waist measurement, TC, HDL-C, LDL-C, TG, Glucose, and atherogenic index (AI) were measured as the cardiovascular disease risk factors; percent body fat, appendicular skeletal muscle mass, total muscle mass, and skeletal muscle index were measured as factors related to sarcopenia. Independent samples t-Test was conducted to analyze differences on the two groups based on the physical activity levels, with ${\alpha}=.05$ the as significance level. According to the results, HDL (p=.017) were higher and AI (p=.007) was lower; percent body fat (p=.008) was lower, and ASM (p=.000), total muscle mass (p=.000), and SMI (p=.001) were higher. In conclusion, moderate intensity physical activities rather than low intensity ones may have positive effects on the cardiovascular disease risk factors and sarcopenia levels, and participation in regular physical activities with at least moderate intensity by various methods may be needed for prevention of illness and healthy life of the elderly.

Salinity Monitoring of Soups of The Institutions Enrolled at Center for Children's Foodservice Management (어린이급식관리지원센터 등록 시설 국물음식의 염도 모니터링)

  • Park, Hyun Nae;Kim, Soon Mi
    • Journal of the East Asian Society of Dietary Life
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    • v.26 no.6
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    • pp.507-516
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    • 2016
  • The salinity of soups of institutions enrolled at the Center for Children's Foodservice Management was monitored to reduce sodium intake of children by continuously managing salinity of soups provided by children food service. Monitoring of salinity was conducted by a salinity meter (SB-1500H, HM digital) three times in 2016 by patrolling children's institutions for the instruction of public health. The average salinity of soups provided by total children's institution showed a significant decrease in salinity - $1^{st}$ 0.45%, $2^{nd}$ 0.41% and $3^{rd}$ 0.39% - as monitoring was proceeded (p<0.01). When salinity of soups was analyzed according to the type of children's institution, the salinity of national and public institutions showed no significant decrease. In contrast, the salinity of private institutions decreased significantly (p<0.05). Depending on the enrollment of the food service, there was no significant difference in average salinity of soups between large food services, which have over 50 children, and small food services, which have less than 50 children. However, all food services showed a salinity decrease from the $1^{st}$ monitoring to the $3^{rd}$ monitoring. Salinity according to the type of soup showed that salinity of clear soup, miso soup, and stew except beef soup decreased from the $1^{st}$ monitoring to $3^{rd}$ monitoring. However, there was no significant difference in salinity according to the type of soup which can be attributed to a large difference in salinity among the same type of soup. The individual soup showing the biggest difference between maximum and minimum salinity of soup was egg soup (0.62%), potato soup (0.54%), and mushroom soup (0.64%). The present average salinity of soup provided by children's institutions was less than 0.5% which is the recommended standard of the Ministry of Food and Drug Safety. However, the salinity of soups should be managed within a certain range including the minimum salinity regarding the taste education of children.

The Change of Riverside Vegetation by Construction of Ecological Stream in Suwoncheon, Gyeonggi Province (경기도 수원천 생태하천 복원사업 이후 식생변화 연구)

  • Choe, Il-Hong;Han, Bong-Ho;Ki, Kyong-Seok
    • Korean Journal of Environment and Ecology
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    • v.24 no.6
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    • pp.723-734
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    • 2010
  • This study aims to analyze the change in vegetation for 10 years after the construction, targeting Suwoncheon, the first domestic ecological stream construction project. As for the section for the study, the section from Gyeonggi bridge to Youngyeon bridge, the first restoration project section, was targeted. The research districts consisted of 3 districts depending on topographical structure. Investigation check cosisted of cross-sectional topographical structure, vegetation status and the structure of herbaceous plant community. As for the cross-sectional topographical structure of the stream, the width of entire stream was 26.5~28.0m and water channel is 10~20m. The area for hydrophilic space was securing spacious riverside. Upper stream of reservoir beam was shallow and slow in reservoir area above weir. Lower stream of reservoir beam, the width of water channel was narrow and ripples were formed. Among species, 9 plants were planted and 6 species plants including Salix gracilistyla, Phragmites communis and Zoysia japonica were planted at the time of construction. In the water side, there were 2 species, such as Zoysia japonica and Trifolium repens, etc, still remained after seeding at the time of constrcution. The planted plants which were observed through this investigation, were 2 species such as Festuca arundinacea and Dactylis glomerata. Apart from the planted plants, arid climate herbaceous plant such as Setaria viridis and Artemisia princeps var. orientalis formed power and the naturalized species variously emerged in 15 species. For revetment, natural stone stacking method was condicted and Salix gracilistyla, Aceriphyllum rossii, etc were planted. But all the planted plants disappeared and now it was covered with Equisetum arvense and Humulus japonicus. It was because that the base for growth and development of the plants was not constructed at the time of restoration in a way of attaching natural stones onto the concrete base. In the water channel, various wetland species including Typha orientalis, Acorus calamus var. angustatus and Phragmites communis, etc, were planted but only Salix gracilistyla, Phragmites communis and Zizania latifolia remained. As for species of the autochthons, Persicaria thunbergii was dominant. In the lower stream of reservoir beam, Humulus japonicus formed forces. In the hydrophilic space, it was necessary to direct the landscape of in-stream vegetation in cosideration of users. For this, planting Miscanthus sacchariflorus in a community was proposed. In the upper stream of reservoir beam, suplementary screen seeding was necessary so that Zizania latifolia, Typha orientalis and Phragmites communis can fit the depth of water. In the Lower stream of reservoir beam, it was necessary to constantly manage Humulus japonicus so that the wetland autochthons species, such as Phragmites communis and Persicaria thunbergii can establish power more stably.

Environmental Factors Affecting the Start and End of Cicadae Calling - The Case Study of Hyalessa fuscata and Cryptotympana atrata - (매미과 울음 시작 및 종료에 영향을 미치는 환경요인 - 참매미, 말매미를 대상으로 -)

  • Kim, Yoon-Jae;Ki, Kyong-Seok
    • Korean Journal of Environment and Ecology
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    • v.32 no.3
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    • pp.342-350
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    • 2018
  • The purpose of this study was to identify the environmental factors that affect the beginning and end of calling by Hyalessa fuscata and Cryptotympana atrata, which are dominant cicada species in the central urban areas of Korea. The study area was Banpo Apartments in Seoul. The research period included two months, being from the end of July to the end of August 2015. We analyzed the start and end time of cicada calling, and on average H. fuscata started calling at 5:21 am and C. atrata started at 7:40 am. The average end time of calling was 6:31 pm for H. fuscata and 7:51 pm for C. atrata. From the scatter plot and box plot results, H. fuscata started calling at 05:00 am, whereas C. atrata consistently stopped calling at 20:00 pm compared to H. fuscata. Multiple regression analysis of the start and end time of cicada calling showed that sunrise time was a factor affecting the start of H. fuscata calling. The end time of H. fuscata calling was affected by sunset time and total cloud cover. The starting time of C. atrata calling was mostly affected by temperature and sunrise time. The effect of temperature was greater than that of sunrise time. The end time of C. atrata calling was strongly affected by sunset time, whereas peak temperature was also shown to affect the end time. From the above results, sunrise and sunset are thought to be the critical factor affecting the start and end time of H. fuscata calling. Therefore, H. fuscata started calling with sunrise, and the end time was also affected by sunset. Temperature was the factor most affecting the start of C. atrata calling and sunset was identified as the factor affecting the end time. Therefore, the start time of C. atrata calling shows variation with daily temperature changes, and C. atrata stop calling simultaneously with sunset.