• Title/Summary/Keyword: 분자인식

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Pre-Service Chemistry Teachers' Awareness of Visually Impaired Students' Learning Situation through Scientific Inquiry about Molecular Structure of Ice in Darkroom (얼음의 분자구조에 대한 암실 속 과학탐구 활동에서 시각장애학생의 학습상황에 대한 예비 화학교사들의 인식)

  • Kim, Hak Bum;Cha, Jeongho
    • Journal of the Korean Chemical Society
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    • v.61 no.5
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    • pp.277-285
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    • 2017
  • The purpose of this study is to investigate the perspective of pre-service chemistry teachers on the learning situations of visually impaired students through scientific inquiry in a darkroom and to propose a teaching and learning method for students with visual impairments. Twenty-one pre-service chemistry teachers from college of education in Gyeongbuk were encouraged to explore individually hands-on model for the molecular structure of ice freely, and had a discussion with a one of the researchers during the activity. All the conversation and discussion were audio-taped and transcribed for analysis. As a result, pre-service chemistry teachers realized that learning situation of the visually impaired students was quite different with their perception while exploring and figuring out hands-on model of the molecular structure of ice in the darkroom. They already learned and could see this model by themselves but also recognized that visually impaired students had inconvenience and difficulty in learning science concepts. Based on these reflections, some pre-service chemistry teachers suggested directions for modification to fit visually impaired students' needs more.

Science Teachers' Perception of the Refractive Index of Media (굴절률에 대한 과학교사들의 인식)

  • Park, Sang-Tae;Yeom, Jun-Hyeok;Yoon, Yeo-Won;Seok, Hyojun
    • Korean Journal of Optics and Photonics
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    • v.28 no.6
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    • pp.334-338
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    • 2017
  • This research aims at investigating science teachers' perception of the refractive index of materials, and thus achieving proper information transmission and teaching of refractive index. Specifically, we have made questionnaires on what physical factors influence the refractive index of a liquid easily available in secondary schools. It was found that 80.0% of science teachers perceived that the density has the greatest influence on the refractive index, among a variety of factors such as molecular structure, the number of molecules per unit volume, mass of each molecule, and the wavelength of light, to mention just a few. This may be due to the fact that current textbooks deal with the refraction of light based on analogy to a mechanical wave. Such a misunderstanding may lead to confusion and misunderstanding for students.

Consumption and Preference for Bokbunja (Rubus coreanus Miquel) Products (복분자 제품에 대한 기호도 및 이용실태 조사)

  • Lee, Jeong-Ae;Park, Geum-Soon
    • Korean journal of food and cookery science
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    • v.27 no.3
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    • pp.11-20
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    • 2011
  • The purpose of this study was to investigate the use and perception of adults concerning bokbunja (Rubus coreanus Miquel) products. Self-administered questionnaires were collected from 502 residents in the Daegu and Gyeongbuk area. According to the survey more females in their 20s responded than males (45.2 and 54.8%, respectively). In total, 82.6% of respondents had an income of under 4,000,000 won per month and most were living in the city. The results regarding knowledge about bokbunja products showed that the bokbunja wine score was highest (3.66), and intake frequency showed that over half of the respondents had never eaten bokbunja products. The preference for bokbunja wine by males was higher than that for females, whereas the others products showed higher scores for females than for males. When asked about how they knew about bokbunja products, 37.0% of males and 46.9% of females responded a family member or neighbor. When purchasing bokbunja products, males and females answered that they considered taste, country of origin, and manufacturer, and price. Approximately 48% of the respondents answered that they purchased bokbunja products in the grocery and department store. As a result, popularization of bokbunja products was based on product development and sales promotion, and the product development factor significantly influenced preference for bokbunja products.

리보솜 불활성화 단백질의 삼차원 구조 규명과 그 구조의 신약개발에의 응용

  • 서세원
    • Proceedings of the Korean Society of Applied Pharmacology
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    • 1994.04a
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    • pp.264-264
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    • 1994
  • 본 연구는 보리 씨앗에 존재하는 리보솜 불활성화 단백질(RIP) 의 삼차원 구조를 X-선 결정학 방법을 이용하여 밝히고, 그 결과로 분자 차원에서 기능을 이해하는 것을 목적으로 하고있다. 리보솜불활성화 단백질은 N-glucosidase 반응을 통하여 단백질 합성을 저해하기 때문에 세포를 죽일 수 있다. 따라서 암세포만을 특정적으로 인식하는 다른 물질과 결합시키면 암세포만을 특정적으로 죽일 수 있는 면역독소로 이용될 수 있다. 또, 최근에는 항바이러스의 작용을 함이 밝혀져 많은 연구가 진행되고 있다. 단백질 삼차원 구조 규명을 위해서는 여러가지 단계가 있는데 지난 번 과제까지 성공적으로 리보솜 불활성화 단백질의 대량 분리와 X-선 결정학의 필수 요건 좋은 결정을 길렀고, 이번에는 구조 해석을 위해 꼭 해결해야하는 위상문제를 극복하기 위하여 여러가지 실험을 진행하였다. 우선, 비슷한 구조인 피마자씨에서 분리한 Ricin의 A-체인과 미국자리공 잎에서 분리한 Pokeweed antiviral protein의 삼차원 분자좌표를 이용하여 분자치환법으로 위상문제 해결을 시도하였다. Ricin 의 A-체인을 이용하였을 때 분자의 위치가 정확히 찾아지지 않았고, 다른 모델인 Pokeweed antiviral protein을 이용하여 X-PLOR 프로그램내의 PC refinement법으로 분자치환을 시도하였다. Euler각도로 (187.37, 22.5, 311.94) 의 회전해 (Rotation solution) 를 가지고 있었고, 이러한 해에 맞추어서 분자를 돌려둔 후, 이동해 (Transaltion solution) 을 구해서 그 위치 (Orientation) 로 분자를 이동하였다. 이 때 R값은 53.9 % (8.0 - 3.5$\AA$) 이였고, 부분좌표 (Fractional coorcdinate) 에서는 0.102, 0.000, 0.261 이고, 직교좌표 (Orthogonal coorclinate) 에서는 4.616, 0.000, 13.167 의 결과를 얻었다.

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Roles of Mannose-Binding Lectin on Innate Immunity and Disease (Mannose-binding lectin의 선천성 면역과 질병에 대한 역할)

  • Jang, Ho-Jung;Park, Jeong-Hae;Chung, Kyung-Tae
    • Journal of Life Science
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    • v.20 no.9
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    • pp.1420-1425
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    • 2010
  • Innate immunity is the first line of host defense consisting of various molecules against infectious challenges. Mannose-binding lectin (MBL) belongs to the collectin protein family which takes part of innate immunity and is able to recognize specific carbohydrates on the surface of a variety of infectious agents acting as a pattern recognition molecule. In this way, MBL differentiates self from non-self and interacts with other molecules of the immune system. MBL genotype shows various MBL2 polymorphisms which are responsible for MBL deficiency in a substantial portion of the entire human population and for susceptibility to infectious disease. Therefore, it has been highlighted in the relationship between genetic variants and clinical significance. Here we focus on presenting anoverview of our understanding of MBL structure and functions.

Structure Analysis of Low Contrast Fax Cover Pages (저해상도 팩스 표지 영상의 구조 분석)

  • 임영규;이성환
    • Proceedings of the Korean Information Science Society Conference
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    • 1998.10c
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    • pp.387-389
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    • 1998
  • 팩스가 보편적인 정보 전달 매체로 자리잡게 됨에 따라 기업체나 관공서 뿐만 아니라 가정에서도 많은 작업이 팩스를 통해 이루어지게 되었다. 이에 따라 팩스 문서의 분석 및 인식의 필요성이 증가하게 되었다. 팩스 문서는 표지와 내용이 두 부분으로 이루어지는데 팩스 문서의 처리를 위해서는 성명, 주소등을 포함하는 팩스 표지의 분석이 중요하다. 따라서 본 논문에서는 팩스 표지 영상의 구조 분석 방법을 제안한다. 제안한 팩스 표지 구조 분석 방법은 팩스 표지가 헤드, 송/수신 정보, 메시지로 구성된다는 점에 착안하여 위치 정보를 이용한 영역 분리에 중점을 두었으며, 팩스 표지의 종류를 몇 가지로 분류하여 도표 형태의 팩스 표지도 분석이 가능하도록 하였다. 분자 인식에서는 팩스 문자 인식에 우수한 성능을 보이고 있는 자소 기반 한글 문자 인식기를 사용하였다. 또한 한글의 자소 모델에 기반한 후처리 방법을 개발하여 인식 오류를 교정하였다.

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Taxonomy of tribe Neillieae (Rosaceae): Neillia (나도국수나무족(장미과)의 분류: 나도국수나무속)

  • Oh, Sang-Hun
    • Korean Journal of Plant Taxonomy
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    • v.46 no.1
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    • pp.13-32
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    • 2016
  • Neillieae was traditionally recognized as a small tribe in Rosaceae, which consists of Neillia, Stephanandra, and Physocarpus. Recently, Stephanandra was merged into Neillia based on molecular phylogenetic analyses, meaning that Neillieae now contains Neillia and Physocarpus. The genus Neillia is distinguished from Physocarpus by ovate to lanceolate leaves with acuminate to caudate apices, racemose or paniculate inflorescences, and a unicarpellate (rarely bicarpellate) gynoecium. Plants of Neillia are distributed from the Himalayas across China and Korea to Japan in the east, and south to Indonesia. This study provides a taxonomic treatment of Neillia based on a morphological examination of herbarium specimens, including types, and field observations, as the second part of the taxonomic revision of the tribe Neillieae. A summary of the phylogeny of Neillia, keys to the species, nomenclatural reviews, descriptions, distribution maps, and lists of specimens examined are provided. Twelve species with ten varieties are recognized in Neillia. A lectotype was designated here for the following species: N. sinensis f. glanduligera and N. thyrsiflora.