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Anti-aging Effect of Amino Acid Complex on the Skin (Amino Acid Complex의 항노화 작용)

  • Kim, Ki-Ho;Kim, Ki-Soo;Kim, Young-Heui;Ko, Kang-Il;Park, Sun-Hee;Kim, Jin-Guk;Chio, Hyun-Jin;Ko, Su-Yeon;Bae, Yoon-Joo;Kim, Yong-Min
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.32 no.2 s.57
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    • pp.81-88
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    • 2006
  • Amino acid complex was made with the composition of amino acids quite similar to that of stratum corneum on the skin. In order to evaluate the efficacy of amino acid complex on the skin as an active cosmetic ingredient, we measured cytotoxicity. TIMP-1 expression, moisturizing effect and the amount of horny substance. In cytotoxicity assay, amino acid complex did not show any cytotoxicity. In moisturizing effect test using corneometer, it showed very good moisturizing effect. In TIMP-1 mRNA assay using RT-PCR, moo acid complex showed the increase of TIMP-1 expression, suggesting that amino acid complex have anti-wrinkle effect. Therefore, amino acid complex may be useful as an active ingredient for anti-aging.

Clinical study of lip balm containing propolis extract and lip applying LED device (프로폴리스 추출물이 함유된 립밤과 LED 기기를 적용한 입술 임상 연구)

  • Moon, Ji-Sun
    • Journal of Convergence for Information Technology
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    • v.12 no.5
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    • pp.225-236
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    • 2022
  • The purpose of this study is to provide clinical information and quantitative data through clinical research on lip balm containing propolis extract and lip application with LED device. Participants in this study were selected as test products for women aged 19 to 50 in Seoul and Gyeonggi Province, and to investigate the effects of LED devices and lip creams on the lips to improve lip elasticity, lip moisture, lip keratin, and lip moisture lasting for 12 hours. Before using the product, immediately after use, after 6 hours of use, after 12 hours of use, and after 2 weeks of use, the use test items are measured and the safety, efficacy, and preference survey of the product is analyzed. The results derived through a series of research procedures are as follows. It has been shown to help lip elasticity, lip moisture, lip keratin improvement, and lip moisture lasting for 12 hours when used once or 2 weeks.

The Study on Skin Safety and Efficacy of Codonopsis Lanceolata Root Fermentation Extract (더덕 발효추출물의 피부 안전성 및 화장품제형에서의 피부개선효과에 관한 연구)

  • Shim, Seung-Bo;Chun, Yong-Jin
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.13 no.11
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    • pp.5623-5627
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    • 2012
  • Codonopsis lanceolata belongs to the Campanulaceae family, which is a perennial herb. It is widely used as an antitussive agent and an expectorant in oriental medicine. Codonopsis lanceolata contains large amounts of polysaccharide and phenolic compounds and is known to have anti-oxidative effect and improve immunity. We evaluated the efficacy and the skin safety and stability of cosmetic that is applied Codonopsis lanceolata extract fermented by lactic acid bacteria. As result, formulation of Codonopsis lanceolata extract improved the human skin moisturizing effect, increased TEWL 196%, skin hydration 15%, and the sebum rate 131%.

A Study on the Effectiveness of Diagnostic Ultrasound Transmission Media (초음파진단시 초음파 전파매질의 유용성에 관한 연구)

  • Lee, Hye Nam;Lim, Cheong-Hwan
    • Proceedings of the Korea Contents Association Conference
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    • 2014.11a
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    • pp.187-188
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    • 2014
  • 초음파 전파 매개물은 초음파의 손실 없는 투과력을 위한 1차적인 목적 이외에 피부위에서 탐촉소자의 부드러운 이동을 위한 부가적인 목적이 있다. 본 연구는 제형이 다른 진단초음파 전파매개물이 갖는 피부 윤활성, 피부 보습성, 건조속도 등의 초음파 매개물의 특징을 측정하고 비교하였다. 마찰계수는 점도가 높을수록 높았으며 제제의 건조속도는 고분자 수화젤이 가장 높았다. 오일 함유량이 많을수록 수분증발이 나타나지 않았다. 피부수분함량에서는 저점도 에멀전이 높은 수분함량을 나타냈으며 수분함량 감소 정도가 가장 완만히 나타났다. 오일성분을 적절히 사용한 에멀전 형태의 초음파 전파매개물은 피부 보습효과, 피부 유연작용의 피부 건강측면과 피부-탐촉소자간의 피부 윤활성면에서 효과적인 제형임을 알 수 있었다.

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Anti-oxidative Activity and Moisturizing Effect of Fermented Puer Tea Extract (발효보이차 추출물의 항산화활성 및 보습효과)

  • Kim, In-Young;Zhoh, Choon-Koo;Han, Sa-Ra;Bang, Young-Bae;Li, Ri-Yuan
    • Journal of the Korean Applied Science and Technology
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    • v.30 no.2
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    • pp.272-279
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    • 2013
  • The fermented puer tea leaves were high concentrated extracted with 50% ethanolic solution in this study. Also, evaluating the anti-oxidative activity and anti-aging effect of this extract, we expected to apply the cosmetic industry. The yield of fermented puer tea extract was 17.9%. The total polyphenol content was 37.5%, tannin content was 7.5%, polysaccharide was 17.9%, unknown compound was 22%, and water content was 8%. Anti-oxidative activity (in-vitro) of fermented puer tea extract by DPPH method was $33.7{\pm}1.8%$ in 30mg/mL, $39.4{\pm}2.2%$ in 50mg/mL respectively. Therefore, we could know that anti-oxidative activity of fermented puer tea extract was effect higher than tocopheryl acetate and greentea extract. The collagen synthesis activity (in-vitro) of fermented puer tea extract was increased with $102.9{\pm}9.9%$ in 1 mg/mL, $111.5{\pm}9.9%$ in 5 mg/mL, $122.7{\pm}12.2%$ in 10 mg/mL, $131.5{\pm}13.7%$ in 30 mg/mL (*p-value£0.05, n=3). Skin moisturizing activity of fermented puer tea extract after application 8 hours was increased 38.5% higher than control samples both tocopheryl acetate and greentea extract. Total moisturizing effect was increased about 32.7% compared to before treatment. Fermented puer tea extract of this study can be applied to the skin care cosmetics industry.

The Preparation of Reversed Micelle Containing Water Soluble Collagen Solution and Their Application on Lip Make up Products (콜라겐 수용액을 함유하는 역미셀의 제조 및 립 제품에 응용)

  • Kim, Young-Ho;Jung, Eun-Ji;Lee, Dong-Won;Lee, Sang-Gil;Pyo, Hyeong-Bae
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.39 no.4
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    • pp.271-279
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    • 2013
  • Water-soluble collagen (30 wt%) was entrapped within oil phase of lipstick using reversed micelle method to improve the moisture capacity of the lipstick. Reversed micelles containing collagen were prepared using caprylic/capric triglyceride as external phase and polyoxyethylene (10) octylphenyl ether (Triton X-100) and 1-dodecanol as surfactant and co-surfactant, respectively. The formation of reversed micelle encapsulating collagen was confirmed by measuring electric conductivity and UV-vis spectrum using methylene blue (MB). The stability and moisture capacity of the lipstick containing 20 wt% collagen encapsulated reversed micelles were observed by measuring rheology property, moisture content and amino acid content. The molecular ratio (W, water-pool) of water to surfactant (Triton X-100) in the most stable reversed micelle was ${\leq}$ 10. The hardness of the lipstick had no difference with that of the lipstick without reversed micelle, and the moisture content was increased to 59% and the amino acid content was 92.7%.

Development of Gel Sheet Mask Based on Physical Properties Study of Tamarindus indica Seed Gum, Ethanol, Polyols, and Acid/Base Reaction (타마린드씨검과 에탄올, 폴리올 및 산·염기 반응의 물성 연구를 바탕으로 한 겔 시트 마스크의 개발)

  • Yeo, Hye Lim;Lee, Hyo Jin;Kang, Hae-Ran;Jung, So Young;Lee, So Min;Kim, Hyung Mook;Kwak, Byeong-Mun;Lee, Mi-Gi;Bin, Bum-Ho
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.47 no.4
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    • pp.305-316
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    • 2021
  • This study relates to the development of a new gel sheet mask that finally does not require support based on the reactivity and acid/base reaction experiments of Tamarindus indica seed gum (TG), ethanol, and polyols. When TG and a specific alcohol was mixed at a certain mixing ratio, a transparent gel is formed by reaction with each component, and thus a gel sheet mask without support might be obtained using the mixture. In order to maximize skin tone improvement, a carbonation system of acid and base reactions was introduced, and skin brightness and moisturizing power were evaluated using a spectrophotometer and a moisture measuring device. Through this study, it is expected that the gelation reaction by hydrogen bonding of TG, ethanol, and polyols can be developed into various types, and the gel sheet mask formulation introduced in this study is expected to help develop new products in the future.

A Case Study on the Factors of Obstacles to Growth of Planted Trees in the Gimcheon Jakjumgogae of Baekdudaegan Ecological Axis Restoration Site (김천 작점고개 백두대간 마루금 복원사업지 내 식재수목의 생육 장애 요인에 관한 연구)

  • Kim, Su-Jin;Park, Hyun-Bin
    • Korean Journal of Environment and Ecology
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    • v.36 no.4
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    • pp.422-432
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    • 2022
  • Soil and micro-climatic environmental monitoring was conducted to evaluate the factors causing tree growth impediments at the Baekdudaegan ecological axis restoration project site. As a result, it was found that the nutrient supply was insufficient in the restoration project site due to the lack of organic matter, total nitrogen and cation exchange capacity of the soil compared to the surrounding forest. After the completion of the restoration, the soil moisture in the autumn decreased more than 7 times faster than that of the surrounding forest, and it was evaluated that the soil moisture was significantly low due to the lack of silt and clay content. In the case of the restoration site, the annual potential evapotranspiration was analyzed to be 975mm, which is approximately two times higher than that of the surrounding forest. The soil moisture of the restoration site in the summer decreased rapidly during the daytime when the amount of insolation increased and this was found to be strongly influenced by the increase in potential evapotranspiration. In order to improve the above factors affecting the tree growth at the Baekdudaegan ecological axis restoration project site, it is necessary to induce the smooth supply of nutrients and water to plants by improving physical proprieties and cation exchange capacity, i.e., using litterfall, humus soil, soil conditioner and organic fertilizer. The results of this study are expected to serve as basic data for the design, construction, and management of ecological axis restoration projects in the future.

Development of High-Functional Hyaluronic Acid/Salmon Extract Formulation Using Gamma-Ray (감마선을 이용한 고기능성 히알루론산/연어추출물 제형개발)

  • Kweon, Dong-Keon;Shim, Jae-Goo;Ha, Man
    • Journal of the Korean Society of Radiology
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    • v.12 no.1
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    • pp.9-16
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    • 2018
  • Hangover after drinking is different from person to person symptoms and degree, but usually thirst, fatigue, headache, general boredom, gastrointestinal disorder, vomiting, diarrhea, deficiency of vitamin appears. This hanging phenomenon is caused by the action of precursors such as ethyl acetate and acetaldehyde, which are the by products of fermentation contained in alcohol and alcohol accumulated in hepatocytes and body. In order to solve the hangover phenomenon, the same Origin as polysaccharide Polydeoxyribonucleotide, which is a nucleic acid-sugar-phosphate complex, which is a semen or testicular extract in salmon extract, and a water soluble salmon extract powder having the same structure and lower price than Polydeoxyribonucleotide And D-Glucuronic acid and N-Acetyl glucosamine. It has excellent biocompatibility, viscoelasticity and moisturizing power. It has effect on reduction of body water loss and skin moisture content in hangover phenomenon. It is antioxidant and skin moisturizing effect Hyaluronic acid was irradiated with gamma rays, and the composition was prepared by using the salmon extract powder and the main raw material. The ethanol degradation, the acetaldehyde reduction amount, the blood acetaldehyde concentration and the acetic acid concentration were measured to evaluate the alcoholysis effect, Skin moisture evaporation rate To examine the evaluation unit water content of the skin was improved determine whether the antioxidant and provide skin moisturizing effect. The addition of ethanol extracts of salmon extracts showed a decrease of 5 to 7 times compared with no addition, and a decrease of 3 to 5 times of acetaldehyde. In addition, the change of acetaldehyde concentration and acetic acid concentration in blood showed a rapid decrease compared to the no - added control group. In addition, when the raw material of hyaluronic acid was used, skin moisture content was high and skin moisture evaporation amount was decreased. Therefore, hyaluronic acid, which is a polysaccharide polymer, has excellent viscoelasticity and moisturizing ability, It is considered to provide antioxidant and skin moisturizing effect. Therefore, it can be said that the composition containing salmon extract powder and hyaluronic acid as a main ingredient is effective for the hangover phenomenon which occurs after drinking.

The Cosmeceutical Property of Antioxidant Astaxanthin is Enhanced by Encapsulation Using Glyceryl Based New Vesicle (글리세릴 베이스의 신규베지클 이용 캡슐화를 통한 항산화성 아스타잔틴의 성질 강화)

  • Kim, Dong Myung;Hong, Weon Ki;Kong, Soo Sung;Lee, Chung Hyun
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.40 no.3
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    • pp.247-257
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    • 2014
  • Oil-in-water nanoemulsions of astaxanthin prepared by new vesicle, glyceryl citrate/ lactate/ linoleate/ oleate, were evaluated thoroughly in terms of cosmeceutical properties such as antioxidant effect, cell viability, influence of protein related enzyme, skin penetration, skin hydration and elasticity. Antioxidant effect and cell viability of nanoemulsion of astaxanthin were evaluated by DPPH and MTT assay. Also other properties of nanoemulsions of astaxanthin were measured by proteome analysis using 2D-PAGE, confocal laser scanning microscope and in-vivo test. We were able to find that the nanoemulsion of astaxanthin is good at scavenging of radical and inhibits the degradation of dermal extracellular matrix with the down-regulation of MMPs and other proteins related to MMP expression. CLSM was adopted for observing penetration of nanoemulsion of astaxanthin and showed high effective penetration rate compared to the nanoemulsion of astaxanthin prepared by conventional lecithin. In-vivo measurement of the nanoemulsions in hydration and elasticity were conducted to 11 Korean female adults for 28 days and showed better results.