• Journal of Korean Medical classics
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• v.18 no.3 s.30
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• pp.126-135
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• 2005

통과분석(通過分析)${\ulcorner}$금궤요약심전${\lrcorner}$경병조문중우재경적주석(痙病條文中尤在痙的註釋), 득출여하결론(得出如下結論) 1. 경병적원인유이(痙病的原因有二) : 외인시태양풍한중감한습(外因是太陽風寒重感寒濕); 내인시혈기음양적손상(內因是血氣陰陽的損傷), 단진액부족시기공통지처(但津液不足是其共通之處). 2. 경병기본속우표병(痙病基本屬于表病), 출현심맥시인감수습사소치(出現沈脈是因感受濕邪所致). 3. 경병(痙病), 출현강직시인감수풍사(出現强直是因感受風邪). 4. 강경유오한증상(剛痙有惡寒症狀), 단유가능인위표실증무오한증상(但有可能認爲表實證無惡寒症狀), 고장원문중적'반'자직접인용과래설명(故將原文中的反字直接引用過來說明). 5. '기맥여고'화'폭복장대'시풍사거이습사잔존적시후출현적('其脈如故’和‘暴腹腸大'是風邪去而濕邪殘存存的時侯出現的). 6. 경병적양명어열증가사용대승기탕(痙病的陽明瘀熱證可使用大承氣湯), 기병불시위료거제조실(其幷不是爲了去除燥實), 이시위료하양명어열(而是爲了下陽明瘀熱), 고실제상사용대승기탕적시후요소심근신(故實際上使用大承氣湯的時候要小心謹愼).

• Journal of the Korean Society of Radiology
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• v.81 no.4
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• pp.972-978
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• 2020

Fentanyl intoxication has occasionally been reported since fentanyl patches became available for medical use. Delayed post-hypoxic leukoencephalopathy is a complication of hypoxia. However, its neuropsychiatric symptoms can be delayed, and it can progress to leukoencephalopathy even after full recovery from coma due to acute intoxication. Herein, we report a case of fentanyl intoxication in a 65-year-old man who was presented to the hospital because of unconsciousness for 13 hours after using ten fentanyl patches simultaneously. Initial brain CT findings were non-specific. Twenty days later, delayed neuropathologic symptoms manifested, and MRI showed bilaterally symmetrical, heterogeneous, confluent high signal intensities on T2-weighted/fluid attenuated inversion recovery MRI in the cerebral white matter with diffusion restriction. This was followed by rapid exacerbation of neuropathological symptoms with diffuse severe cerebral atrophy over 1 year.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.16 no.2
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• pp.239-250
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• 2005

Objective : The purpose of this study was obtaining data on the efficacy and safety of risperidone in child and adolescent psychiatric patients. Method : Thirty one children and adolescents (males n=18, females n=13, age ranged from 5.4 to 17.3 years) treated with risperidone were selected among child and adolescent psychiatric inpatients of Seoul National University Hospital from January, 2001 to June, 2002, and charts for them were reviewed retrospectively. Results : The primary psychiatric disorders treated with risperidone were schizophrenia and other psychosis, bipolar I disorder with psychotic features, Tourette's disorder, autism spectrum disorders, mixed receptive and expressive language disorder, attention deficit-hyperactivity disorder, conduct disorder and obsessive-compulsive disorder. twelve of these had comorbid mental retardation. Primary target symptoms of risperidone were psychotic symptoms (n=13 or $41.9\%$), behavioral symptoms (n=10 or $32.3\%$) including aggression, impulsivity, hyperactivity, stereotypy nonresponsive to other psychiatric treatments, and chronic and severe tics (n=8, $25.8\%$). The efficacy of risperidone was measured by clinical global improvement (CGI) for target symptoms, $67.7\%$ of subjects showed moderate or marked improvements and its therapeutic effect appeared to be maintained during at least 7.5 months. Mean daily dosage of risperidone was $0.05{\pm}0.01mg/kg$, the group with psychotic symptoms had significantly higher mean daily dosage (0.07mg/kg) compared with other two groups (0.04mg/kg) with behavioral symptoms or tics. A variety of adverse events were reported in this study : weight gain (n=23) most commonly reported, extrapyramidal symptoms (n=15), autonomic symptoms (n=6), sedation (n=5) and symptoms related to hyperprolactinemia (n=2) etc. Although there was no drug change related to the adverse events of risperidone, and $90\%$ of subjects at their last visits were maintained on it, thus its tolerability appeared good. Conclusions Results suggest that risperidone may be relatively safe and effective drug in managing a wide variety of child and adolescent psychopathologies such as psychotic symptoms, behavioral symptoms including aggression, impulsivity, hyperactivity and stereotypy nonresponsive to other psychiatric treatments, and chronic and severe tics. Controlled and long-term studies of efficacy and safety of risperidone treatment for children and adolescents are recommended in the future.

• The Academic Congress of Korean Shoulder and Elbow Society
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• 2006.11a
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• pp.122-127
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• 2006

관절와 상완 관절의 후상방의 병적 변화로 통증이 유발되는 internal impingement는 overhead athlete뿐만아니라 nonathlete에서도 비교적 흔한 질환이다. 특징적인 동통, 특정 동작에 악화되는 증상 및 선택적인 검사 및 MRI검사 등을 통해 진단할 수 있으며, 확진은 관절경적 검사에 의한다. 보존적인 치료가 질병초기에는 효과적이다. 만약 증상이 지속 또는 악화된다면 수술적인 치료가 필요하며 다양한 수술적 방법들이 있다. 주 병변에 대한 적극적인 치료가 이루어져야 하며, 전방관절의 microinstability or laxity에 대한 치료, tight posteroinferior capsule에 대한 capsular release 및 동반된 rotator cuff 및 labrum의 병변에 대한 치료가 이루어 져야 한다.

• Journal of Hospice and Palliative Care
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• v.12 no.1
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• pp.1-4
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• 2009

The aim of palliative radiotherapy (RT) is to control cancer-related local symptoms with minimal radiation reaction. About one third of all radiation treatments are given with palliative intent. Indications for RT in symptom palliation are as follows: Pain from bone metastasis, pressure symptom from brain and spinal cord, obstruction of bronchus, esophagus, superior vena cava and malignant cancer bleeding from bronchus, urinary tract, uterine cervix and rectum. In hospice palliative care, RT is very effective for symptom palliation and improvement of quality of life without influence on survival.

• Korean Journal of Psychosomatic Medicine
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• v.10 no.1
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• pp.55-60
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• 2002

Central pontine myelinolysis(CPM) and Extrapontine myelinolysis(EPM) are uncommon neurologic disorders associated with osmotic inequality between the extracellular fluid compartment and intracellular fluid compartment in the brain. Myelinolysis can occur in hyponatremia and after rapid correction of hyponatremia. It may be caused by various metabolic disturbances such as chronic alcoholism, malnourishment, cancer, chronic renal failure and organ transplantation. The authors reported a 43-year-old male patient who have received a kidney transplantation because of chronic renal failure due to diabetic nephropathy. The patient manifested psychotic symptoms such as delusion, loosened association, hallucination, inappropriate affect and aggressiveness as a sequele of CPM and EPM. He also showed neurocognitive impairment such as disorientation, memory impairment, decresed intelligence and aphasia. These manifestations are rare in CPM and EPM. We discuss the clinical features, diagnosis, course and management of the patient which may be clinically significant in the neuropsychiatric aspect especially at the consultation-liaison field.

• Korean Journal of Biological Psychiatry
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• v.14 no.2
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• pp.122-128
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• 2007

Objectives : The aim of this study was to investigate relationships between psychotic symptoms and cognitive functions in schizophrenia. Methods : The study group was composed of 36 schizophrenic patients. Positive, negative, and disorganization symptoms were assessed using the PANSS. Verbal, visuospatial, attention, memory, and executive functions were assessed using a battery of cognitive tests. Results : Correlation analysis between symptom vs. cognitive measures showed that (a) positive symptoms were significantly correlated with no cognitive measures, (b) negative symptoms were significantly correlated with all cognitive measures, and (c) disorganization symptoms were significantly correlated with executive and memory measures. Correlation analyses between symptom vs. cognitive factors showed that negative-disorganization factor is significantly correlated with executive-memory factor. Conclusion : Significant relationships were confined mostly to frontal symptoms vs. frontal cognitive functions. Thus, the relationships may be mediated mainly by variations in severity of frontal pathology among patients.

• Journal of Korean Orthopaedic Sports Medicine
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• v.1 no.1
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• pp.4-8
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• 2002

관절와 상완관절 상부의 병적 변화로 유발되는 회전건개의 내적 충돌(internal impingement)이나 상부 관절순의 병변(SLAP)은 동통, 특정한 위치에서의 증상 및 MRI 검사등을 통해 의심할 수 있으며, 확진은 관절경적 검사에 의한다. SLAP 병변과 internal impingement의 병변은 서로 영향을 끼칠 수 있으며 특정적인 관절 순의 손상 양상 및 회전건개의 손상을 유발하게 된다. SLAP병변의 치료는 병형의 양상에 따라 결정되며, internal impingement의 치료는 전방관절불안정성에 대한 치료가 주가 된다.

• Korean Journal of Oriental Medicine
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• v.11 no.1
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• pp.61-82
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• 2005

통과술내용적연구득출이하결논(通過上述內容的硏究得出以下結論) 1. 송대의학적특점시유료흔다일계열신적지식, 갱가중시료대리논적정리(更加重視了對理論的整理), 대당시모종병적각종병인병기적인식진행통일귀납(對當時某種病的各種病因病機的認識進行統一歸納), 병통과분석총결병인병기게시료전형증상급주요치법(幷通過分析總結病因病機揭示了典型症狀及主要治法). 2. 송대의가재연구부여생리기적기혈병기적특수성방면다중시혈(宋代醫家在硏究婦女生理期的氣血病機的特殊性方面多重視血), 재임신병중중시기기옹새(在姙娠病中重視氣機壅塞), 재산후병중중시악혈부진(在産後病中重視惡血不盡). 3. 도료송대(到了宋代), 재연구부과병병인방면(在硏究婦科病病因方面), 종이전적중시외인전위중시내인(從以前的重視外因轉爲重視內因), 이차폐기료종전적귀신적병인(而且廢棄了從前的鬼神的病因), 재방실병인상강조료요적당(在房室病因上强調了要適當). 재진단상(在診斷上), 수봉건예교적영향(受封建禮敎的影響), 이결합병기적전형적증상위표준(以結合病機的典型的症狀爲標準).

• The Journal of the Korean bone and joint tumor society
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• v.19 no.2
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• pp.78-82
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• 2013

Langerhans cell histiocytosis is known as one of the diseases related to excessive proliferation of normal monocytes and has the variety of clinical courses and treatment. Especially, in cases with the spine, it shows a feature of single or multiple osteolysis. According to the location, disease progression and concomitant symptom, variety of treatments (observation, radiotherapy, chemotherapy, surgery, etc.) have been attempted, however, appropriate treatment has not been established yet. The authors introduce the case of single system Langerhans cell histiocytosis which involves cervical and lumbar vertebrae simultaneously with bone marrow destruction and pathologic fracture.