• Journal of Life Science
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• v.28 no.5
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• pp.597-604
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• 2018

Although the core mechanisms of Attention Deficit/Hyperactivity Disorder (ADHD) are unknown, several ADHD-associated proteins have been studied. G-protein - coupled receptor kinase interacting protein-1 (GIT1) is a multifunctional adapter protein that affects neuron growth and dendrite formation. GIT1-deficient mice have shown ADHD-like behavior and also recovered through amphetamine treatment. In this study, gliotransmitters were investigated in both intracellular and extracellular space from GIT1-deficient mice. To measure the amount of gliotransmitters, primary astrocyte cultures were taken from the cerebral and cerebellar cortices of wild (WT), hetero (HE), and knock-out (KO) mice. Major gliotransmitters were analyzed using high-performance liquid chromatography. It was observed that the amount of excitatory and inhibitory gliotransmitters were dependent on genotype and showed a change in excitation/inhibition ratios. Interestingly, the major excitatory gliotransmitter, glutamate, existed at the lowest level in WT mice, but the amount of inhibitory gliotransmitters, gamma-aminobutyric acid (GABA) and glycine, varied depending on brain region. Remarkably, an increased amount of GABA was measured at the intracellular cerebrum in WT mice compared with KO mice. It was presumed that KO mice would secrete more inhibitory gliotransmitters to compensate for GIT1 depletion or else acquire a defect to reuptake-secreted GABA. This may be a possible mechanism for ADHD pathology.

• Journal of the Korean Chemical Society
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• v.50 no.1
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• pp.23-31
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• 2006

carbon modified methods were used for the preconcentration and determination of copper in some real samples using the flame atomic absorption spectrometry. The copper ions was adsorbed quantitatively on the activated carbon due to their complexation with 4- amino-2, 3-dimethyl-1-phenyl-3-pyrazoline (ADMPP) or 4-(4- methoxybenzylidenimin) thiophenole (MBITP). The adsorbed copper on solid phase was eluted quantitatively using small amount of nitric acid. The influence of important parameters including pH, amount of carrier, flow rate, amount of activated carbon and type and concentration of eluting agent for obtaining maximum recovery were investigated. The methods based on ADMPP and MBITP at optimum conditions is linear over concentration range of 0.05-1.5 g mL-1 and 0.05-1.2 g mL-1 of copper with correlation coefficient of 0.9997 and 0.9994 and both detection limit of 1.4 ng mL-1, respectively. The preconcentration leads to enrichment factor of 310 and break through volume of 1550 mL for both ligands. The method has a good tolerance limit of interfering ion and a selectivity that has been successfully applied for the determination of copper content in real sample such as tap, spring, river and waste water.

• Journal of the Korea Concrete Institute
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• v.23 no.3
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• pp.321-330
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• 2011

Recently, the effects of high temperature and fiber content on the residual mechnical properties of high-strength concrete were experimentally investigated. In this paper, residual mechanical properties of concrete with water to cement (w/c) ratios of 0.55, 0.42 and 0.35 exposed to high temperature are compared with those obtained in fiber reinforced concrete with similar characteristics ranging from 0.05% to 0.20% polypropylene (PP) fiber volume percentage. Also, factors including pre-load levels of 20% and 40% of the maximum load at room temperature are considered. Outbreak time, thermal strain, length change, and mass loss were tested to determine compressive strength, modulus of elasticity, and energy absorption capacity. From the results, in order to prevent the explosive spalling of 50 MPa grade concretes exposed to high temperature, more than 0.05 vol. % of PP fibers is needed. Also, the cross-sectional area of PP fiber can influence the residual mechanical properties and spalling tendency of fiber reinforced concrete exposed to high temperature. Especially, the external loading increases not only the residual mechanical properties of concrete but also the risk of spalling and brittle failure tendency.

• Journal of the Korean Electrochemical Society
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• v.10 no.4
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• pp.306-310
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• 2007

Characteristics of GDL (Gas Diffusion Layer) mainly determine the gas diffusion and water removal in a cell, thereby changing the performance and affecting durability of PEFC. To optimize the water management and understand the two phase flow in a GDL, it is important to study the behaviors of GDL micro structure under the real operating condition. In the clamped condition of cell, the GDL beneath the rib is more compressed than beneath the channel. Many researches on physical, electrochemical, mechanical behaviors of gas diffusion layer has been conducted. However, changes in surface properties under clamped condition have rarely studied. In present study, the morphology of broken connections of carbon fibers and detachment of PTFE coatings on the fibers were shown from the microscopic observations. In addition, changes in wetting properties of GDL by compression were investigated by using XPS and liquid uptake methods. The hydrophobic characteristics of GDL surface beneath the rib of the flow field plate are changed due to the deformation of micro structure.

• The Korean Journal of Ecology
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• v.28 no.2
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• pp.93-98
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• 2005

The effects of the presence of a submerged plant, Zizania latifolia, on physico-chemical characteristics, including Eh, pH, and concentrations of nitrogen and phosphorus in the sediments were studied under pot culture condition. It was shown that Eh value at reduced layer of the sediments was higher in the planted pots than in the non-planted. It was also revealed that $NH_4^+-N$ concentration of the sediments in the planted pots was lower than that of the non-planted, which might be due to the uptake by the plants. In contrast, $NO_3^--N$ concentration in the sediment increased in the presence of the plants compared to the non-planted, which might be attributed to oxygen released from the roots to the reduced layer. The concentration of organic phosphorus in the sediments was much higher than that of NAIP at the beginning of the planting experiment. However, at the end of the experiment, it was reversed; NAIP concentration was much higher than that of organic phosphorus, possibly indicating the transformation of organic phosphorus to NAIP during the experimental period. Both concentrations of $NH_4^+-N$ and $PO_4^{3-}-P$ in the overlying and percolated water were lower in the planted pots than in the non-planted. The concentration of $NO_3^--N$ in the percolated water, however, was higher in the planted pots than in the non-planted. The data was discussed with regard to the potential effects of a submerged plant on dynamics of phosphorus and nitrogen in the rhizosphere of the sediment.

• Journal of Dental Rehabilitation and Applied Science
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• v.35 no.4
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• pp.244-252
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• 2019

Proper positioning of maxillary incisors is key to success of surgery combined treatment. Establishing surgery plan would be a difficult job if maxillary incisors are lost. Patient who lost all of her maxillary incisors due to accident came for orthodontic treatment. Through careful modification of maxillary archform, pre-surgical orthodontic treatment was conducted with four prosthetic space consolidation. Position of incisors was decided by help of 3D prosthetic set-up, and 1-jaw surgery was planned. After relative short treatment period of 28 months, final prosthesis was done. When alveolar bone loss happens, harmonious prosthesis of upper incisors is difficult. Utilizing mandibular set-back surgery and incisor positioning using 3D set-up could make a better environment for treatment outcome. Strategic pre-surgical orthodontic treatment can allow shorter time and less number of prosthetics.

• Journal of Korean Society of Coastal and Ocean Engineers
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• v.30 no.6
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• pp.242-252
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• 2018

It is well known that an Oscillating Water Column Wave Energy Converter (OWC-WEC) is one of the most efficient wave absorber equipment. This device transforms the vertical motion of water column in the air chamber into the air flow velocity and produces electricity from the driving force of turbine as represented by the Wells turbine. Therefore, in order to obtain high electric energy, it is necessary to amplify the water surface vibration by inducing resonance of the piston mode in the water surface fluctuation in the air chamber. In this study, a new type of OWC-WEC with a seawater channel is used, and the wave deformation by the structure, water surface fluctuation in the air chamber, air outflow velocity from the nozzle and seawater flow velocity in the seawater channel are evaluated by numerical analysis in detail. The numerical analysis model uses open CFD code OLAFLOW model based on multi-phase analysis technique of Navier-Stokes solver. To validate model, numerical results and existing experimental results are compared and discussed. It is revealed within the scope of this study that the air flow velocity at nozzle increases as the Ursell number becomes larger, and the air velocity that flows out from the inside of the air chamber is larger than the velocity of incoming air into the air chamber.

• Journal of the Korea Institute of Building Construction
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• v.19 no.3
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• pp.209-217
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• 2019

EMP (Electromagnetic Pulse) usually means High Power Electromagnetic Wave (HPEM). In the case of the shielding plate against the EMP, there is a possibility of deterioration of the electromagnetic wave shielding performance due to the skill of the constructor, bad construction, deformation of the shielding plate at the connection portion (joint portion). The inefficient use of space due to the separation distance is also pointed out as a problem. Therefore, this study aims to derive the optimum electromagnetic shielding condition by applying ATMSM to concrete as a part of securing electromagnetic wave shielding performance with reflection loss against concrete wall. Experimental parameters included concrete wall thickness and application of Zn-Al ATMSM. For the concrete wall, the wall thickness was 100 to 300mm, which is generally applied, and experimental parameters were set for the application of Zn-Al metal spraying method to evaluate electromagnetic shielding performance. Experimental results showed that as the thickness increases, the electromagnetic shielding performance increases due to the increase of absorption loss. In addition, after the application of Zn-Al ATMSM, the average shielding performance increased by 56.68 dB on average, which is considered to be increased by the reflection loss of the ATMSM. In addition, it is considered that the shielding performance will be better than that when the conductive mixed material and the ATMSM are simultaneously applied.

• Composites Research
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• v.35 no.4
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• pp.277-282
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• 2022

In this study, a smart material applicable to speed bumps was developed using low-cost starch and waterbased suspensions, and their properties were investigated. Viscosity and shear stress according to the shear rate was measured by a rheometer to observe shear thickening behavior according to starch concentration. The shear thickening phenomenon and applicability to speed bumps were identified macroscopically via drop weight test and bike driving test, measuring the vibration after impact with a driving speed of 5-25 km/h. As a result of the viscosity measurement, shear thickening occurred after the shear thinning region at the beginning, and the critical strain causing the shear thickening phenomenon decreased as the concentration of starch increased. Also, the viscosity and shear stress increased significantly with the increase of the starch concentration. As a result of the drop weight test and the bike driving test, the suspension was changed to a solid-like state in a short time, and the impact energy was absorbed in the fluid. The shear thickening phenomenon easily occurred as the concentration of the fluid and the applied impact (velocity) increased. Therefore, it can be proposed the development of a smart speed bump material that operates in the range of 5-25 km/h with a Non-Newtonian fluid based on water and starch.

• Korean Journal of Ecology and Environment
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• v.37 no.4 s.109
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• pp.436-447
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• 2004

Wetland plants have evolved specialized adaptations to survive in the low-oxygen conditions associated with prolonged flooding. The development of internal gas space by means of aerenchyma is crucial for wetland plants to transport $O_2$ from the atmosphere into the roots and rhizome. The formation of tissue with high porosity depends on the species and environmental condition, which can control the depth of root penetration and the duration of root tolerance in the flooded sediments. The oxygen in the internal gas space of plants can be delivered from the atmosphere to the root and rhizome by both passive molecular diffusion and convective throughflow. The release of $O_2$ from the roots supplies oxygen demand for root respiration, microbial respiration, and chemical oxidation processes and stimulates aerobic decomposition of organic matter. Another essential mechanism of wetland plants is downward water movement across the root zone induced by water uptake. Natural and constructed wetlands sediments have low hydraulic conductivity due to the relatively fine particle sizes in the litter layer and, therefore, negligible water movement. Under such condition, the water uptake by wetland plants creates a water potential difference in the rhizosphere which acts as a driving force to draw water and dissolved solutes into the sediments. A large number of anatomical, morphological and physiological studies have been conducted to investigate the specialized adaptations of wetland plants that enable them to tolerate water saturated environment and to support their biochemical activities. Despite this, there is little knowledge regarding how the combined effects of wetland plants influence the biogeochemistry of wetland sediments. A further investigation of how the Presence of plants and their growth cycle affects the biogeochemistry of sediments will be of particular importance to understand the role of wetland in the ecological environment.