• Proceedings of the Korean Information Science Society Conference
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• 2011.06c
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• pp.184-187
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• 2011

셀 트래킹의 목적은 셀의 이동(translocation), 분할(mitosis), 통합(fusion), 아포토시스(apoptosis), 셀의 모양 변형, 셀들 간의 상호 작용 등을 포함하는 모든 셀의 행동들을 분석하기 위한 것이다. 셀은 시간이 경과함에 따라 새롭게 나타나기도, 죽기도 하며 한 개 이상의 셀이 부분적으로 겹쳐 클러스터를 형성하기도 하고 클러스터는 다시 여러 개의 셀로 분리되기도 한다. 본 연구에서는 현미경으로부터 얻은 이미지에서 셀 트래킹을 위한 이미지 처리 방법과 오목 정점을 이용하여 셀과 클러스터를 구분하여 계수하는 방법을 제시한다. 또한 타원 근사법(ellipse fitting)을 통해 클러스터를 몇 개의 셀로 분리하기 위한 방법을 제시하고 결과를 분석한다.

• Electronics and Telecommunications Trends
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• v.27 no.6
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• pp.182-196
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• 2012

본고에서는 미래인터넷 환경으로서 사람 사물 공간 간의 새로운 관계망으로서의 만물지능통신 기반 초연결 네트워크(All Things on Ambient Network: ATAN)에 주목한다. ATAN은 네트워크를 구성하는 행위 주체로서 인간과 인간의 소통에서 인간과 사물, 사물과 사물, 공간과 공간으로 확장되어 데이터, 정보 그리고 행동을 초연결하는 시스템의 총체로 본다. 본고에서는 ATAN이 포스트 스마트 사회 인프라로 이행하는 기여 지점에서 인간과 비인간의 의사소통 티핑 포인트(tipping point)로서의 ATAN 싱귤래리티(singularity) 개념이 존재함을 제안한다. 이러한 전제하에서 ATAN 싱귤래리티의 발생 구도를 설정하고, 웹의 과거 현재 미래 고찰을 통해 ATAN 패러다임으로 전개되는 과정을 고찰한다. 또한 주요국의 미래인터넷 전략 분석을 통하여 ATAN으로의 공통 지향성을 추출한다. 이러한 작업을 통해 우리나라의 미래 네트워크의 전략적 콘셉트로서 ATAN 국가전략기조를 제시한다. 마지막으로 첨단 네트워크 기술이 사회변형을 촉진하고 사회가 기술을 인간 중심으로 수용하는 건강한 기술사회 복합체(technology-social complex)를 지향할 것을 강조하였다.

• Journal of the korean academy of Pediatric Dentistry
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• v.35 no.2
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• pp.351-356
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• 2008

Cerebral palsy, a range of non-progressive syndromes of posture and motor impairment, is a common cause of disability in childhood. Self-injurious behavior(SIB) is deliberate harm to the body without suicidal intend, often involving repetitive actions that cause tissue damage. One of the most common orofacial self-injurious behavior is chewing tongue, lip or oral mucosa. This kind of SIB in children is not common in normal children. High occurrence rates are observered in cases of syndromatic, mentally retarded children, and children with congenital disease. Various methods such as behavior modification, behavior control by drugs, body restraints, application of dental appliance, surgery and extraction of teeth have been suggested to control those self-injurious behavior. Using mouthguard as one of dental applainaces is the most conservative and appropriate method in terms of reducing oral self-injurious habits and protection of tissue. This case report describes a child with cerebral palsy who presented with self-injurious ulceration of lip and buccal mucosa. A modified mouthguard was effective in preventing self-injurious oral trauma in a child with cerebral palsy.

• The KIPS Transactions:PartD
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• v.17D no.5
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• pp.337-346
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• 2010

Timing diagram is popularly utilized for the reason of its advantages; it is convenient for timing diagram to describe behavior of system and it is simple for described behaviors to recognize it. Various techniques are needed to test systems described in timing diagram. One of them is a technique to derive the system into a certain condition under which a test case is effective. This paper proposes a technique to automatically generate the test input sequence to reach the condition for systems described in timing diagram. It requires a proper input set which satisfy transition condition restricted by input waveform and timing constraints to generate a test input sequence automatically. To solve the problem, this paper chooses an approach utilizing the linear programming, and solving procedure is as follows: 1) Get a Timing diagram model as an input, and transforms the timing diagram model into a linear programming problem. 2) Solve the linear programming problem using a linear programming tool. 3) Generate test input sequences of a timing diagram model from the solution of linear programming problem. This paper addresses the formal method to drive the linear programming model from a given timing diagram, shows the feasibility of our approach by prove it, and demonstrates the usability of our paper by showing that our implemented tool solves an example of a timing diagram model.

• Journal of Life Science
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• v.31 no.11
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• pp.995-1003
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• 2021

Chromatin remodeling regulates gene expression through epigenetic mechanisms. Aberrations in histone modification have been associated with depression-like behaviors in animal models. Additionally, growing evidence also indicates that epigenetic modification is associated with depression. p11 (S100A10) has been implicated in the pathophysiology of depression both in human and rodent models. In the present study, we investigated alterations in histone acetylation and methylation at the promoter of the p11 gene in the hippocampus of mice subjected to chronic unpredictable stress (CUS). C57BL/6 mice were exposed to CUS daily for 3 weeks. Depression-like behaviors were measured with the forced swimming test (FST). The levels of hippocampal p11 expression were analyzed by quantitative real-time polymerase chain reaction (PCR) and Western blotting. The levels of acetylated and methylated histone H3 at the promoter of p11 were measured by chromatin immunoprecipitation followed by real-time PCR. CUS-exposed mice displayed depression-like behaviors with prolonged immobility in FST. CUS led to significant decreases in the expression of p11 at both protein and mRNA levels. Meanwhile, there was a decrease in histone H3 acetylation (Ac-H3) and H3-K4 trimethylation (H3K4met3) and an increase in H3-K27 trimethylation (H3K27met3) at the p11 promoter. These results indicate that chronic stress causes the epigenetic suppression of p11 expression in the hippocampus.

• Journal of Christian Education in Korea
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• v.77
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• pp.7-27
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• 2024

This study addresses the crucial role of Christian Religious Education (CRE) amidst civic polarization, moral disimagination, and learned helplessness. It begins her personal background as a 1.5-generation Vietnamese American and her academic engagement in immigrant faith and the challenges of teaching faith in violent contexts. The work underscores the public dimension and impact of religious education, highlighting its potential for fostering critical capacities for public engagement. However, that study observes a prevalent disconnection between congregational culture and the aim of public engagement, leading to a form of learned helplessness among students and communities. The researcher draws on Paulo Freire's concepts of "critical hope" and the need for a curriculum that transcends mere content delivery to foster transformative engagement with societal issues. The document critiques the disimigination machine that undermines critical thinking and collective resistance, as articulated by Henry Giroux, and explores the concepts of "learned helplessness" as a barrier to environmental and social activism. The researcher advocates for a theopoetic and theopolitical approach to education that nurtures hope and practical engagement with the world's injustice. She emphasizes small acts of theopoetic and theopolitical hope as transformative practices, using an example from Ferguson, Missouri, to illustrate how public liturgy and protest can mediate hope and justice. The document concludes with a call for a life-long, life-wide, and life-deep curriculum of enchantment towards responsible participation in societal repair, rooted in Christian hope.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.16 no.2
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• pp.160-172
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• 2005

Attention-Deficit/Hyperactivity Disorder(ADHD) is the most common neurodevelopmental disorder in child psychiatry. The etiology or ADHD is not completely understood, but involved in genetical and/or neurocognitive deficits. This article reviews the current state of the literature pertaining to the neurodevelopmental aspects of ADHD. Although the neurodevelopment of ADHD remains unclear, emerging evidence documents its genetic and neurobiologic underpinnings. A pathophysiology of ADHD has not been fully characterized, although genetic, neurobiologic, neuroimaging, and neuropsychological studies of ADHD consistently implicates dysfunction in the fronto-subcortical network and abnormality in the dopaminergic and noradnergic systems. Furthermore some suggests that the timing of aberrant brain development in ADHD could be in early gestation and genetic and/or early environmental influences on brain development in ADHD are fixed, nonprogressive. Although many studies provide evidences for the important or psychosocial or environmental adversities in ADHD, they may be not specific predictors of ADHD but nonspecific triggers of an underlying predisposition or modifiers of the course of disorder.

• The Mathematical Education
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• v.60 no.3
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• pp.297-319
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• 2021

The present study explored a relationship between mathematical understandings of teachers and ways in which their knowledge transferred in designing lessons for hypothetical students from Gess-Newsome (1999)'s transformative perspective of pedagogical content knowledge. To this end, we conducted clinical interviews with four secondary mathematics teachers of their solving and teaching of equation writing. After analyzing the teacher participants' attention to Key Developmental Understandings (Simon, 2007) in solving equation writing, we sought to understand the relationship between their mathematical knowledge of the problems and mathematical knowledge in teaching the problems to hypothetical students. Two of the four teachers who attended the key developmental understandings solved the problems more successfully than those who did not. The other two teachers had trouble representing and explaining the problems, which involved reasoning with improper fractions or reciprocal relationships between quantities. The key developmental understandings of all four teachers were reflected in their pedagogical actions for teaching the equation writing problems. The findings contribute to teacher education by providing empirical data on the relationship between teachers' mathematical knowledge and their knowledge for teaching particular mathematics.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.15 no.11
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• pp.2493-2499
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• 2011

With growth of nano-bio industry, it is of significant importance to develop an automated system to exploit cell behaviors, including migration, mitosis, apoptosis, shape deformation of individual cells and their interactions among cells in the process of cell growth. In this paper, we proposed preprocessing techniques, a classification method which classifies clusters (overlapping multiple cells) from cells and an automated method which counts the number of cells and clusters in order to analyze 2D or 3D deformations of the cells in the real-time images from microscope in the cell culture. We conducted the 3T3 cell images taken from each thirty-minute interval. It showed the average 99.8% accuracy automatically for separating cells and clusters.

• The Journal of the Korea Contents Association
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• v.10 no.7
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• pp.169-178
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• 2010

This paper has conducted a theoretical re-inquiry on Gilles Deleuze' thought about Alfred Hitchcock' film based on the image of thought in relation with the concept and theory about film. So, the purpose of this article is to explore that film can acquire the academic significance as a philosophy including an academic denomination of social science and Arts. According to the findings, Gilles Deleuze appeared that A. Hitchcock used the mental-image which can transform the perception-image, the action-image, and the affection-image in film and make the relation including the way which it is developed between character and event. Also, as the mental-image can change the meaning of film, camera is the essence and mental referent. And the mental-image makes the other images a specific frame, permeates into image and transforms it. This paper sets limits to some problems that Deleuze's thought about film generalizes to filmic theory, but has a importance to inquiry new research as a theoretical introspection for the practical discussion about the relation between film and philosophy.