• Korean Journal of Microbiology
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• v.37 no.1
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• pp.28-36
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• 2001

These studies were carried out to understand the mechanisms of genes which are related in cell cycle progression at G1/S phase. Mutants involved in cell cycle progression and regulation in Saccharomyces cerevisiae were isolated and characterized. To isolate new mutants, we screened the sensitivity to ciclopirox olamine (CPO) which inhibits the cell cycle traverse at or very near the G1/S phase boundary in HeLa cell and budding yeast. As results, we isolated 30 mutants and named cos(ciclopirox olamine sensitivity: cos27∼cos57) mutants. To determine the phenotype of mutants, we examined the sensitivity to methyl-methane sulfonate (MMS) and hydroxyurea (HU). Several mutants were sensitive to MMS and HU. According to these Phenotypes, cos mutants were grouped into four. Group I mutants are cos27, cos28, cos32, cos33, cos36, cos37, cos40, cos42, cos46, cos50, cos52 and cos53 which show MMS, HU sensitivities and might act at a checkpoint pathway during S phase. Group II mutants are cos43 and cos48 which show MMS sensitivities and might act at a checkpoint pathway during Gl or G2 phase. Group III mutants are cos35, cos47, cos54, cos55 and cos56 which show HU sensitivities and might act at a progress pathway during S phase. Finally, Group IV mutants are cos29, cos30, cos31, cos34, cos38, cos39, cos41, cos44, cos45, cos49, cos51 and cos57 which show only CPO sensitivities. Moreover, we examined the terminal phenotype of mutants under fluorescent microscope and then found one of S phase checkpoint related mutant(cos37). Furthermore, we constructed the heterozygote strain between mutant and wild type haploid strains to study their genetic analysis of cos mutants.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.26 no.12C
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• pp.199-207
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• 2001

We propose an adaptive shaping controller equipped with the technologies of shaping and buffering VoIP packets arriving at the receiving end by the CAM-type controller. In order to conceal interarrival packet delay variation, the conventional jitter buffers force them to be too large, thereby causing the audio quality to suffer excessive delay. However, by using our proposed method, the delay caused by shaping operation dynamically increases or decreases on the level of jitter that exists with in the IP network. This makes the delay accommodates adaptively the network jitter condition. The less jitter network has the fewer delay the shaping controller requires for jitter elimination. And the CAM-type method generally makes the shaping operation faster and leads to processing packets in as little time as can. We analyse the packet loss and delay performance dependency on the average talk ratio and the number of jitter buffer entries in shaping controller. Surprising, we show that the average delay using our shaping controller is about 70msec. This performance is much better than with the delay equalization method which forces the receiving end to delay about 60msec.

• Journal of Korea Water Resources Association
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• v.33 no.3
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• pp.375-382
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• 2000

The surface hydrology of large watershed is susceptible to several preferred stable states with transitions between stable states induced by stochastic fluctuations. This comes about due to the close coupling of land surface and atmospheric interaction. An interesting and important issue is the duration of residence in each mode. In this study, mean transition tunes between the stable modes are analyzed for the Han River Basin. On the basis of historical data, the nonlinear water balance model is calibrated for the Han River Basin. The transition times between the stable modes in the model are studied based on the stochastic representation of the physical processes and on the calibrated model parameters. This study has implications for prediction of the transition time between stable modes or residence times, that is, the time the system spends in a given stable modes, since this would be equivalent to predicting the duration of drought or wet conditions.

• Journal of the Mineralogical Society of Korea
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• v.25 no.2
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• pp.77-84
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• 2012

Anatase, one of the $TiO_2$ polymorphs, is known to show different phase transition paths depending on its crystalline and shape. Particle size of 15~25 nm anatase has been subjected to high-pressure Raman spectroscopy and X-ray diffraction studies using a diamond anvil cell. We observe that the starting sample transforms to an amorphous phase above approx. 20 GPa, which is retained upon pressure release to ambient condition. This is in contrast to previously established transition to baddeleyite phase and we suspect difference in the particle distribution state trigger phase instability of nanoparticles and hence amorphization.

• Journal of the Korean Association of Geographic Information Studies
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• v.14 no.3
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• pp.223-235
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• 2011

Although ordinary least squares (OLS) regression analysis can be used to examine the spatial relationships between environmental equity and urban quality of life, this global method may mask the local variations in the relationships between them. These geographical variations can not be captured without using local methods. In this context, this paper explores the spatially varying relationships between environmental equity and urban quality of life across the Atlanta metropolitan area by geographically weighted regression (GWR), a local method. Environmental equity and urban quality of life were quantified with an integrated approach of GIS and remote sensing. Results show that generally, there is a negatively significant relationship between them over the Atlanta metropolitan area. The results also suggest that the relationships between environmental equity and urban quality of life vary significantly over space and the GWR (local) model is a significant improvement on the OLS (global) model for the Atlanta metropolitan area.

• Korean Journal of Plant Taxonomy
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• v.36 no.4
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• pp.279-292
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• 2006

Patterns of morphological variation in Cirsium japonicum complex were examined using numerical analysis, and the delimitation of taxa was evaluated. Principal components analysis of taxa using 24 morphological characters and 11 leaf characters revealed the presence of two major groups; C. japonicum var. japonicum and C. japonicum var. spinosissimum. Circium japonicum f. nakaianum could be included in the category of C. japonicum var. japonicum. In conclusion, Korean C. japonicum complex was composed of two varieties and one form, C. Japonicum var. japonicum, C. japonicum var. spinosissimum, and C. japonicum var. spinosissimum f. alba.

• The Journal of Korean Academy of Prosthodontics
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• v.49 no.4
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• pp.341-345
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• 2011

Genetic association study has been progressed in medicine along with advance in genetic technology. It focused on the individual differences in genotype due to errors occurring during DNA duplication, which can cause vulnerability to specific diseases. Polymorphism defines the varieties in phenotype due to those genetic variations. Polymorphism due to change in one DNA base sequence is called as a Single Nucleotide Polymorphism. In the near future, the evaluation of relative risk to specific disease according to SNP will be essential part of fundamental of medicine for the diagnosis, treatment and prevention. Dental caries and periodontal diseases has been first subject to genetic association study in dentistry and broaden out to other areas like bone formation and resorption. This article presents the current state of genetic association study and its application to dentistry.

• Proceedings of the Zoological Society Korea Conference
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• 2001.04a
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• pp.89.1-89
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• 2001

• Korean journal of applied entomology
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• v.52 no.4
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• pp.265-271
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• 2013

Morphometric analysis of Lycorma delicatula was performed to confirm whether local individuals had a geographical difference in their wing variations. The L. delicatula individuals were collected from 10 localities in Korea, China, and Japan, and 14 morphometric characteristics selected from the forewing were analyzed. The Korean individuals were similar to the ones from the northern area of the Yangtze River, but less similar to the others from the southern area of the Yangtze River. The individuals from Seoul and Buan were very similar to those from Shanghai. In case of wing spots, the individuals from Beijing had relatively small spots, while the ones from Linan had big spots. The Japanese individuals had a relatively large wing size.

• Journal of Animal Science and Technology
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• v.52 no.1
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• pp.9-16
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• 2010

A previous study has shown that the g.17924G>A polymorphism of fatty acid synthase (FASN) is associated with unsaturated fatty acid composition in the Hanwoo beef, hence this study was conducted to evaluate the effect of single nucleotide polymorphisms (SNPs) within FASN gene on the selection phenotypes of Hanwoo breeding stock. A total of 925 progeny test steers were used to genotype g.11280G>A, g.13125T>C, and g.17924G>A polymorphisms and significant associations were found among g.11280G>A, g.17924G>A, and carcass traits, such as carcass weight, backfat thickness, and beef quantity index. No significant association was found between g.13125T>C and carcass traits. Although the degree of linkage disequilibrium (LD) was not strong among g.11280G>A, g.13125T>C, and g.17924G>A in the LD analysis, four major haplotype classes were formed with the genotypic information within the FASN gene; the frequencies of the halpotypeswere -GCG-[0.378], -ATG-[0.301], -GTA-[0.191], and -ACG-[0.063], respectively. Phenotypic association was performed among these haploptypes, and the haplotype 2 (-ATG-)was significantly associated with higher carcass weight when compared to the other haplotypes, i.e. haplotype 1 (-GCG-) and haplotype 3 (-GTA-). A copy number of the FASN haplotype 3 (-GTA-) had also a significant association with carcass weight of subjects. In conclusion, it was observed that two polymorphisms (g.11280G>A and g.17924G>A) and their haplotypes within the FASN gene are consistently associated with carcass traits. Therefore, it is desirable to use the FASN polymorphisms for pre-selection program as genetic marker with improved carcass yield and beef quality of the Hanwoo sire at the Hanwoo Improvement Center as well as for commercial Hanwoo producers, the FASN genotypic information can be used for a part of selecting Hanwoo dam for superior calf production.