• Title/Summary/Keyword: 변이분석

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Evidence-based Field Research on Health Benefits of Urban Green Area (과학적 근거를 바탕으로 한 도시녹지의 건강편익에 관한 연구)

  • Lee, Ju-Young;Park, Kuen-Tae;Lee, Min-Sun;Park, Bum-Jin;Ku, Ja-Hyeong;Lee, Joon-Woo;Oh, Kyong-Ok;An, Ki-Wan;Miyazaki, Yoshifumi
    • Journal of the Korean Institute of Landscape Architecture
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    • v.39 no.5
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    • pp.111-118
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    • 2011
  • With increasing interest in health promotion and quality of life, growing attention has been focused on the beneficial effects of urban green area. However, very few evidence-based approaches have been conducted on the health-related benefits of urban greenery. Therefore, this study examined the health-related benefits of green areas using physiological and psychological indices to obtain evidence-based data on these benefits. Twenty male university students were selected as subjects. Data were collected when participants viewed landscapes in a green area or an urban area for fifteen minutes. This research was reviewed and approved by the Ethics Committee of School of Medicine, Chungnam National University. Physiological data in the green area revealed significantly decreased heart rates, significantly increased high-frequency value of heart rate variability, an index of parasympathetic activity, and reduced salivary cortisol concentration, a stress hormone, compared to the urban area. Psychological tests showed the green area significantly reduced the negative mood state and psychological symptoms, and significantly increased the positive mood state. Our data provided evidence for the health-related benefits of green areas, and the findings of this study support that green areas can play a critical role in health promotion for urban residents, by positively affecting autonomic nervous and endocrinal activities.

An Active Learning-based Method for Composing Training Document Set in Bayesian Text Classification Systems (베이지언 문서분류시스템을 위한 능동적 학습 기반의 학습문서집합 구성방법)

  • 김제욱;김한준;이상구
    • Journal of KIISE:Software and Applications
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    • v.29 no.12
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    • pp.966-978
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    • 2002
  • There are two important problems in improving text classification systems based on machine learning approach. The first one, called "selection problem", is how to select a minimum number of informative documents from a given document collection. The second one, called "composition problem", is how to reorganize selected training documents so that they can fit an adopted learning method. The former problem is addressed in "active learning" algorithms, and the latter is discussed in "boosting" algorithms. This paper proposes a new learning method, called AdaBUS, which proactively solves the above problems in the context of Naive Bayes classification systems. The proposed method constructs more accurate classification hypothesis by increasing the valiance in "weak" hypotheses that determine the final classification hypothesis. Consequently, the proposed algorithm yields perturbation effect makes the boosting algorithm work properly. Through the empirical experiment using the Routers-21578 document collection, we show that the AdaBUS algorithm more significantly improves the Naive Bayes-based classification system than other conventional learning methodson system than other conventional learning methods

A Korean familial case of hereditary complement 7 deficiency (선천성 보체 7번 결핍을 가진 한국인 한 가족)

  • Kim, Moon Kyu;Lee, Kyung Yul;Lee, Jun Hwa
    • Clinical and Experimental Pediatrics
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    • v.52 no.6
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    • pp.721-724
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    • 2009
  • Meningococcal infections can be associated with abnormalities of the complement system, which contains 5 terminal complement proteins. Furthermore, deficiencies in 1 of these 5, complement component 7 (C7), leads to the loss of complement lytic function, and affected patients show increased susceptibility to recurrent meningococcal meningitis and systemic Neisseria gonorrhoeae infection. In September 2003, an 11-year-old female patient presented at our outpatient department with high fever, lower leg pain, headache, and petechiaes. She rapidly progressed to coma but later achieved full recovery due to prompt treatment. Her final diagnosis was meningococcal sepsis and arthritis. Her elder brother also had a similar bacterial meningoencephalitis history, which encouraged us to perform analyses for complement component and gene mutations. Resultantly, both the brother and sister were found to have the same mutation in the C7 gene. Subsequently, vaccinations of the meningococcal vaccine meningococcal vaccine ($Menomune^{(R)}$) were administered. However, in September 2006, the brother expired due to acute micrococcus meningoencephalitis. At present, the 16-year-old female patient is healthy. Here, we report a Korean family with a hereditary C7 deficiency with susceptibility to meningococcal infections due to C7 gene mutation.

Studies on the Response of Barley Varieties to Nitrogen Application and Seeding Methods (보리의 안전증수를 위한 질소비료의 효율적 이용에 관한 연구)

  • Hong-Suk Lee;Eun-Woong Lee;Ho-Young Lee
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.20
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    • pp.152-162
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    • 1975
  • Five barley varieties were compared under six 1evels of nitrogen fertilization and two methods of cultural management, conventional and drill seeding. The increase in grain yield and nitrogen content of the leaves showed a significant linear regression from added increaments of nitrogen in Haganemugi and Olbori, particulary under drill seeding. The other varieties resulted in various degrees of lodging and no significant increases in yield. The spike number per square meter was the major component of yield, but when the spike number per square meter was sufficient, 1000 grain weight was equally as important as a component of yield.

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Response of Korean ginseng (Panax ginseng C. A. Meyer) to 2, 4-D I . Effects of 2, 4-D concentrations on Growth and Root Yield (제초제 2, 4-D에 대한 고려인삼의 반응 I. 2, 4-D의 농도가 인삼의 생육 및 근수량이 미치는 영향)

  • 조재성
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.34 no.4
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    • pp.422-427
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    • 1989
  • Weeds may compete detrimentally with the ginseng for moisture and nutrients but hand weeding is the only practical means of eliminating weeds after crop establishment. To define the effects of 2, 4-D herbicide application on the plant growth and root yield of Korean ginseng (Panax ginseng C. A. Meyer). the herbicide 2, 4-D was applied as a foliar spray with the rates of 0.5. 1.0. 1.5 and 2.0 times of the recommended herbicide dosage 70ml/l0a. The Korean ginseng treated with 2, 4-D in the rate of two times concentration was indistinguishable from nontreated plants in visual rating for foliar symptoms. There were no significant differences of the leaf length and width as well as the stem length and diameter in check plants and those recieving 2, 4-D treatments. The. berry maturing in 3 and 4-years old ginseng was not inhibited with 2, 4-D treatment. The root weight of the 4-years old ginseng plant was not reduced by 2, 4-D application of 2 times dosage. However. when the ginseng seedling was treated with 2, 4-D. detrimental phenomena as stem bending and dicoloration of marginal part of seedling leaf were occured but stem bending was recovered in a few days.

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Estimation of Pollutants Loading from Non-Point Sources Based on Rainfall Event and Land use Characteristics (강우강도와 토지이용을 고려한 비점오염물질 부하량 산정에 관한 연구)

  • Lee, Hye-Won;Choi, Nam-Hee;Lee, Yong-Seok;Choi, Jung-Hyun
    • Journal of Korean Society of Environmental Engineers
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    • v.33 no.8
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    • pp.572-577
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    • 2011
  • The unit load has simply been used to estimate total pollutant loading from non-point sources, however, it does not count on the variable pollutant loading according to land use characteristics and rainfall intensity. Since pollutant emission from the watershed is strongly dependent on the rainfall intensity, it is necessary to find out the relationship between pollutant loading and rainfall intensity. The objective of this study is to develop simple and easy method to compute non-point source pollution loads with consideration of rainfall intensity. Two non-point source removal facility at Gyeongan-dong (Gwangju-si) and Mohyeon-myeon (Yongin-si), Gyeonggi-do was selected to monitor total rainfall, rainfall intensity, runoff characteristics and water quality from June to November, 2010. Most of Event Mean Concentrations (EMC) of measured water quality data were higher in Gyeongan which has urban land use than in Mohyeon which has rural land use. For the case of TP (Total Phosphorus), Mohyeon has higher values by the influence of larger chemical uses such as fertilizer. The relationship between non-point source pollution load and rainfall intensity is perfectly well explained by cubic regression with 0.33~0.81 coefficients of determination($R^2$). It is expected that the pollution loading function based on the long-term monitoring would be very useful with good accuracy in computing non-point source pollution load, where a rainfall intensity is highly variable.

Response Characteristics of Perceived Stress Response Inventory in Patients with Upper Gastrointestinal Disorder (상부 위장관 장애 환자에서의 스트레스반응 지각척도의 반응특성)

  • Suh, Yong-Woo;Cho, In-Hee;Shin, Kwang-Chel;Chung, Yong-Kyoon
    • Korean Journal of Psychosomatic Medicine
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    • v.8 no.2
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    • pp.172-180
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    • 2000
  • Objectives : We investigated the characteristics of perceived stress response and relationship between some variables of gastrointestinal symptoms(esp., dyspepsia) and subscales of perceived stress response inventory(PSRI) in patients with upper gastointestinal disorder when they perceived stress. Methods : 84 patients with upper gastrointestinal disorder(gastritis, gastric ulcer, duodenal ulcer etc.) and 94 normal controls completed the PSRI developed by Korean psychiatrists. The patient group performed the questionnaire including some variables of gastrointestinal symptoms. Results : Internal consistency was statistically significant in all subscales of PSRI. The patient group was significantly higher at total score of PSRI, general somatic symptom subscale score, specific somatic symptom score than control group. As the result of stepwise regression analysis for relationship between some variables of gastrointestinal symptoms ans subscales of PSRI, specific somatic symptom subsclae closely related with illness duration, past illness history and severity of symptom, and the lowered cognitive function & general negative thinking subscale related with the existence of emotional distress. Conclusion : Patients with upper gastrointestinal disorder showed stronger perceived stress response than control group and they experiences somatic symptoms related to autonomic nervous system and/or gastrointestinal symtoms rather than emotional, cognitive, behavioral symtoms when they perceived stress. They also responded to stress as they expeirenced specific somatic symtom when they had long illness duration, past illness history, and high severity of symptom and the existence of emotional distress could develop lowered congnitive function and general negative thinking.

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Screening and Isolation of a Gene Encoding 4-Hydroxyphenylpyruvate Dioxygenase from a Metagenomic Library of Soil DNA (토양의 DNA로부터 4-Hydroxyphenylpyruvate Dioxygenase 유전자 탐색 및 분리)

  • Yun, Sang-Soon;Lee, Jung-Han;Kim, Soo-Jin;Kim, Sam-Sun;Park, In-Cheol;Lee, Mi-Hye;Koo, Bon-Sung;Yoon, Sang-Hong;Yeo, Yun-Soo
    • Applied Biological Chemistry
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    • v.48 no.4
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    • pp.345-351
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    • 2005
  • To access the natural products of uncultured microorganisms, we constructed and screened the metagenomic DNA libraries by using a cosmid vector and DNA inserts isolated directly from soil. Initial screening of the libraries in Escherichia coli resulted in the isolation of several clones that produce a dark brown color when grown in LB medium. One of the positive clones, designed pYS85C, was transposon mutagenized and the DNA surrounding the transposon insertions in cosmids that no longer conferred the production of brown pigment to E. coli was sequenced. Annotation of the pYS85C sequence obtained from the transposon mutagenesis experiment indicated a single 393 amino acid open reading frame (ORF) with a molecular mass of about 44.5 kDa, predicted to be a 4-hydroxyphenylpyruvate dioxygenases (HPPDs), was responsible for the observed brown pigment. In a BLAST search against deposited sequence, the translated protein from this ORF showed moderate-level identity (>60%) to the other known HPPDs and was most conserved in the C-terminal region of the protein. These results show that genes involved in natural product synthesis can be cloned directly from soil DNA and expressed in a heterologous host, supporting the idea that this technology has the potential to provide novel natural products from the wealth of environmental microbial diversity and is a potentially important new tool for drug discovery.

Yearly Changes of Precipitation Component in the Iksan Area (익산지역 강수성분의 연차적 변이)

  • Lee, Kyeong-Bo;Lee, Deog-Bae;Lee, Sang-Bok;Kim, Jae-Duk;Park, Chan-Won
    • Korean Journal of Environmental Agriculture
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    • v.25 no.1
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    • pp.1-6
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    • 2006
  • This study was carried out to investigate yearly change in the precipitation component and the source strength to acid precipitation at Iksan area from 1997 to 2003. The average ratio of acid precipitation was 70.0% in 1997, 56.3% in 1998 and 36.4% in 2003. On the other hand, it ranged from 6.9 to 19.2% when precipitation was less from 1999 to 2002. The average annual wet depositions of major ionic component in precipitation were calculated by multiplying equivalent concentration by precipitation. The order of major anion component in precipitation was ${SO_4}^{2-}>Cl^->{NO_3}^-$. On the other hand, the concentration of cation component were ${Ca_2}^+>Na^+>{NH_4}^+>{Mg_2}^+>K^+$ in order. The negative correlation was shown between pH and ionic component in precipitation except for ${Ca_2}^+\;and\;Na^+$. The correlation coefficient between pH and ${SO_4}^{2-}$ was highly significant as -0.508, which suggests that ${SO_4}^{2-}$ played important role in increasing the acidity of precipitation. Also the anions such as ${SO_4}^{2-}\;and\;{NO_3}^-$ were highly significant with cations such as ${Ca_2}^+,\;{Mg_2}^+,\;K^+,\;{NH_4}^+\;and\;Na^+$. As a result though pH was enable to use the acidity index of precipitation in somewhere, evaluating only pH in precipitation was insufficient as the index to establish corresponding strategy for acid rain.

Landslide Types and Susceptibilities Related to Geomorphic Characteristics - Yeonchon-Chulwon Area - (지형특성에 따른 산사태의 유형 및 취약성 - 연천-철원지역을 대상으로 -)

  • 김원영;이사로;김경수;채병곤
    • The Journal of Engineering Geology
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    • v.8 no.2
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    • pp.115-130
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    • 1998
  • An analysis on landslide types and susceptibilities associated with geomorphic characteristics has been conducted with 916 landslide inventories in Yeonchon-Chulwon District, where two day's heavy rainfall was concentrated on July, 1996. The precipitation during the 2 days, which is equivalent to 0.372 of event cofficient, can cause large landslides based on Olivier's equation. Sliding materials are dominantly composed of debris mixed with rock fragments and soil derived from colluvium and residual soils. 66% of the landslides are belong to debris flow md 23% are due to sediments flow, in accordance with the classification of sliding materials. Most of landslides(> 90%) are small and shallow, less than l00m in length and about 1m in depth, and classified as transitional type. Granite is more susceptible as much as 4.7 times than metamorphic rocks and 2.7 times than volcanic rocks, probably due to higher weathering grade of granite. The highest landslide frequency is concentrated on the areas between 200 and 300m in height and on the slopes between $10-20^{\circ}$ in dgree. More than 50% of landslides occurred under these geomorphic conditions. Consequently, colluviums and residual soils distributed on the gentle slopes are most susceptible to the landslides of the area.

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