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김재홍
- KOREAN POULTRY JOURNAL
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- v.19 no.3 s.209
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- pp.50-53
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- 1987
농장에는 전국적으로 각종 바이러스가 만연되어 있다. 갑작스런 환경의 변화나 계군에 스트레스 요인을 만들어주면 질병이 발생한다. 질병유발을 사전에 예방하려면 백신 프로그램에 의한 꾸준한 이행이 요망된다.
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Kim, Doo;Ahn, So-jeo;Jeoung, Seok-young;Hwang, Jae-woong;Pak, Son-il
- Journal of Veterinary Clinics
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- v.21 no.2
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- pp.87-92
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- 2004
This study was undertaken to compare the serological response of dogs to four commercially available combination vaccines and three different vaccination schedules to canine distemper virus (CDV). A total of 120 healthy puppies (20 puppies per group) at 6 weeks of age were randomly assigned to one of four vaccines [C, G, K, and V (or V3) groups] and one of vaccination schedules [V2 and V4 groups]. At six, nine, and 12 weeks of age, puppies in each group were vaccinated with one of four combination vaccines subcutaneously. And puppies in V2 and V4 groups were vaccinated with V vaccine every 2 weeks and 4 weeks, respectively. The serological responses to CDV component of the vaccines were determined by measuring SN titers. The immunogenicity of V vaccine was superior to the other vaccines and optimum vaccination schedule was 3 times vaccination with 3 weeks-interval starting vaccination at 6 weeks of age. Although puppies were vaccinated at 6 weeks of age, the geometric mean CDV titers of puppies in all groups by 9 weeks of age were under the protective level. Therefore, prophylactic measures should include isolation of young dogs from the dog population until vaccination can be expected to provide protection.
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