• Title/Summary/Keyword: 방사선 보호

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두경부암의 6MV 광자선 치료 시 표면선량 증가를 위한 Spoiler의 유용성 평가

  • 이강혁;김원택;이화중;김대영
    • The Journal of Korean Society for Radiation Therapy
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    • v.14 no.1
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    • pp.41-47
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    • 2002
  • 1.목적 두경부암(head and neck Ca)과 쇄골상부(Supraclavicular)에 6MV 광자선으로 치료 시 치료부위(Target volume)가 피부에서 대략 $1^{\sim}2mm$정도 깊이에 위치할 경우, 6MV 광자선의 선량분포는 표면선량이 낮아서 치료에 적합하지 않기 때문에 Bolus와 같이 사용하지만 Skin Sparing(피부보호)효과의 손실로 피부의 손상이 발생할 수 있다. 이러한 이유로 피부의 보호와 치료 시 표면선량의 증가를 위해 Spoiler(산란판)를 제작하여 측정 후 그 특성을 이해하고 선량의 분포를 통하여 Bolus와 비교한 후에 Spoiler의 유용성에 대해 평가하고자 하였다. 2.방법 Siemens사 선형가속기(PRIMUS)의 6MV 광자선을 사용하여 Spoiler의 사용여부 및 Spoiler의 사용 시에는 조사면의 크기를 $5{\times}5,\;7{\times}7,\;10{\times}10,\;15{\times}15,\;20{\times}20cm^2$로 하고 Spoiler와 표면과의 거리는 6, 10, 15cm로 바꾸어 가면서 물팬톰(PTW. 독일)을 이용해 깊이와 측방에 따른 선량분포를 Markus 전리함(PTW. 독일)으로 측정하였으며 전리함의 방수를 위해 씌어진 방수 캡 때문에 표면선량을 별도의 고형 팬톰으로 측정하였다. 표면의 측정선량은 전리함의 측면 벽 등에 의한 선량 측정치의 증가 현상으로 과 반응을 보였으며 이를 교정하였다. 그리고 측정된 데이터를 치료계획 시스템(Pinnacle 6.0m)으로 비교, 분석하였다. 3.결과 Spoiler의 사용 시 3cm깊이 측정선량 백분율과 Spoiler를 사용하지 않은 해당 치료 조사면의 3cm깊이 선량의 백분율에 일치하도록 하여 가상의 치료 깊이인 2mm에서 측정값을 비교하여 본 결과 조사면 $5{\times}5,\;10{\times}10,\;20{\times}20cm^2$에서 OPEN시 62, 64, $70\%$, Bolus는 97, 97, $99\%$로 Spoiler의 사용 시 표면과의 거리가 6cm에서 82, 98, $103\%$, 10cm에는 72, 89, $101\%$, 15m에 65, 79, $96\%$로 나타났으며 표면에서의 측정값을 비교하여 본 결과 OPEN시 11, 17, $27\%$, Bolus는 84, 84, $86\%$, Spoiler의 사용 시 6cm에서 40, 71, $93\%$, 10cm에는 25, 50, $81\%$, 15cm에 18, 36, $67\%$를 나타내었다. 또한 3m깊이에서의 측방 선량분포에서 Spoiler의 거리변화(6, 10cm)는 심부선량의 변화에 영향을 주지 않는 것으로 확인할 수 있었다. 그리고 위의 실험측정치를 치료계획 시스템에 입력하여 선량분포를 확인한 결과 Spoiler를 사용하는 경우 OPEN에 비해 선량분포 영역을 표면으로 끌어 올릴 수 있으며 Bolus 보다 피부 보호효과는 어느 정도 유지가 되는 것을 보여주었다. 4.결론 이와 같이 Spoiler는 Bolus와 비교하여 6MV 광자선의 build up 영역을 표면으로 증가시키는 동시에 Skin Sparing(피부보호)효과를 유지할 수 있으며 두경부암의 치료에서 Spoiler의 사용이 가능한 조건으로는 조사면이 $5{\times}5cm^2$에서 Spoiler와 표면과의 거리가 6cm일 때, $7{\times}7cm^2$에서 6cm, 10cm였고 $10{\times}10cm^2$는 10cm, 15cm로, $15{\times}15cm^2$는 15cm의 간격으로 평가되었다. 또한 $20{\times}20cm^2$의 조사면, Spoiler가 6cm 간격 인 경우 Bolus를 사용한 것 보다 더욱 높은 표면선량을 나타내었다. 그러나 Spoiler와 표면간의 거리를 다르게 함으로써 깊이에 따라 선량분포를 다양하게 나타낼 수 있기 때문에 표면선량의 증가와 피부의 보호를 위해 환자의 피부 두께, 실제 치료 부위의 깊이 등을 고려한다면 Spoiler를 사용하는 것이 bolus를 사용하는 것보다 더 유용하게 적용할 수 있을 것으로 사료된다.

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Research on a Valuation Standard and the Actual Condition About Security Management in PACS (PACS에서 보안관리 평가기준 연구와 실태조사)

  • Jeong, Jae-Ho;Dong, Kyung-Rae;Kweon, Dae-Cheol;Son, Gi-Gyeong;Kim, Hyun-Soo;Kang, Hee-Doo
    • Journal of radiological science and technology
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    • v.31 no.4
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    • pp.347-353
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    • 2008
  • This study is to prepare an evaluation standard about personal information protection and security management of a medical institution and to build up a grade standard of evaluation in PACS environment. We built up evaluation index based on 10 detailed items in four big categories (political security, technical security, data management security and physical security) by referring to ISO17799 (BS 7799), HIPPA (Health Insurance and Portability and Accountability Act of 1996) and domestic medical law. We have investigated at the thirty places where medical facility with the extracted security criteria and security evaluation index. Average score of physical security list, one of the big categories, was 18.5/20 (93%) at all medical institutions. Political security score was 18.5/30 (62%), data management security score was 12/20 (60%) and technical security score was 17.5/30 (58%). Therefore, security evaluation score was average 67 in 30 general hospitals, which was 4th level. The results showed that it is necessary to establish evaluation and management standard about personal information protection and security consciousness which are weak in PACS environment.

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Analysis of Counting Rate according to Presence or Absence of Detector's Protector in Beta-rays Measurement using Geiger-Muller Counter (Geiger-Muller 계수관을 이용한 베타선측정에서 디텍터 보호유무에 따른 계수율 분석)

  • Jang, Ji-Yong;Jeong, Moon-Taeg;Song, Jong-Nam;Ha, Jae-Jun;Han, Jae-Bok
    • Journal of the Korean Society of Radiology
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    • v.12 no.1
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    • pp.31-37
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    • 2018
  • In the surface contamination test using the end-window Geiger-Muller type counter, the wrap is used as a method for protecting the detector exposed to the outside in order to measure the beta-rays. We analyze the effect of this method on the measurement rate and the correction factor, and wanted to make it clear to radiation workers that excessive use of the wrap can affect the measured value of the beta-rays. The experimental method was to compare and analyze the change of the beta-rays measurement counting rate and the calibration factor according to the wrap thickness using the beta-rays with different energy of 3 KBq, 1.5 KBq and 0.3 KBq. The subjects of this study were the end-window Geiger-Muller type counter which were held at the calibration center certified by Korea Laboratory Accreditation Scheme (KOLAS) in March 2012, Cl-36 (Chlorine) and Sr-90 (Strontium) were used as the source of beta radiation. The measurement counting rate decreased with increasing wrap thickness, and the calibration factor increased with increasing wrap thickness. Since the changes of the measurement counting rate and the calibration factors can reduce the accuracy of the instrument readings, but also have a significant impact on detector contamination and damage, so there is a need to find out what thickness of wrap is most effective. If we using a wraps with thickness that show a low rate of change of the measurement counting rate and the calibration factor, it will protect the detector and minimize the effect on the measured value of the beta-rays.

리포트 - 식품안전, 식량안보와 수확후 관리기술

  • Kim, Byeong-Seok
    • Life and Agrochemicals
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    • s.253
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    • pp.42-43
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    • 2009
  • 지금 세계는 인구증가로 인한 시량부족이라는 커다란 위기단계에 직면해있다. 현재 70억, 2050년까지 90억 이상의 사람들에게 충분한 식량공급과 식품품질을 확보하는 것은 국제사회가 처한 매우 중대한 도전이다. 급격히 증가하는 식량 수요를 만족시키기 위한 대부분의 해결책들은 필수적으로 농산물의 생산량 증가에 기반하고 있지만, 이제는 지구 환경을 보호하는 지속농업을 유지하면서 세계 식량생산량의 25%에 해당되는 수확 후 손실을 최소화하는 방향으로 접근하는 것에 초점을 맞추어야 할 것이다. 저온저장은 수확 후 손실을 줄이는데 핵심적인 역할을 해오고 있다. 현재 방사선, 건조, 염장, 고압가공, 통조림 등 많은 수확후 보존기술들이 부패하기 쉬운 음식에 적용되고 있기는 하나, 이들 어떤 기술도 저온저장 기술처럼 소비자가 요구하는 생산물 저장수명 연장과동시에 초기의 물리적, 화학적, 영양학적, 감촉 특성을 유지시켜 주지는 않는다. 따라서 저온저장기술의 이용 증대만이 식품의 양과 질 측면에서 보다나은 전 세계인의 영양공급을 확보할 수 있게 할 것이다.

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Radioprotective Effect of Panax Ginseng in Mouse Bone-marrow (생쥐에서 방사선방호제로서의 인삼효과에 관한 연구)

  • Chae, Ki-Moon;Choi, Keun-Hee;Kim, Young-Ho;Kim, Kwang-Yoon;Bom, Hee-Seung;Kim, Ji-Yeul;Lee, Chong-Bin
    • Journal of Radiation Protection and Research
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    • v.22 no.1
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    • pp.1-7
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    • 1997
  • Radiation protection by post-irradiation injection of the ginseng extract in mice was studied. Male ICR mice, 7 weeks old, were orally injected with ginseng extrat(100mg/kg) for 10 days, and with physiologocal saline as the control. Immediately after final injection, mice were whole body irradiated with 5.08Gy(Cs-137 ${\gamma}$-ray, central dose rate : 654Gy/h) which induced Bone marrow death. At 24h after irradiation, micronucleus test and metaphase analysis in bone-marrow were carried, blood cell were counted and the survival rate were carried for 30 days after the irradiation. Stimulated recovery by the extract was observed in thrombocyte count, but that phenomenom was not showed in the erythrocyte and leucocyte counts. The 30-day survival ratio was 5% and 65% for the control and experimental group. Frequencies of micronuclei per 1000 polychromatic erythrocytes were 79.5${\pm}$1.5 in experimental group, 185.9${\pm}$35.8 in control. And Abnormal chromosomes per 50 metaphases were 112 in experimental group and 143 in control.

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The usefulness of Forward IMRT for Head and Neck Cancer (두경부(Head & Neck)종양에서 Forward IMRT 유용성에 관한 고찰)

  • Baek Geum Mun;Kim Dae Sup;Park Kwang Ho;Kim Chung Man
    • The Journal of Korean Society for Radiation Therapy
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    • v.15 no.1
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    • pp.41-52
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    • 2003
  • I. Purpose The dose distribution in normal tissues and target lesions is very important in the treatment planning. To make the uniform dose distribution in target lesions, many methods has been used. Especially in the head and neck, the dose inhomogeneity at the skin surface should be corrected. Conventional methods have a limitation in delivering the enough doses to the planning target volume (PTV) with minimized dose to the parotid gland and spinal cord. In this study, we investigated the feasibility and the practical QA methods of the forward IMRT. II. Material and Methods The treatment plan of the forward IMRT with the partial block technique using the dynamic multi-leaf collimator (dMLC) for the patients with the nasopharyngeal cancer was verified using the dose volume histogram (DVH). The films and pinpoint chamber were used for the accurate dose verification. III. Results As a result of verifying the DVH for the 2-D treatment plan with the forward IMRT, the dose to the both parotid gland and spinal cord were reduced. So the forward IMRT could save the normal tissues and optimize the treatment. Forward IMRT can use the 3-D treatment planning system and easily assure the quality, so it is easily accessible comparing with inverse IMRT IV. Conclusion The forward IMRT could make the uniform dose in the PTV while maintaining under the tolerance dose in the normal tissues comparing with the 2-D treatment.

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$\cdot$도민의 복지증지과 건강 지킴이로 거듭 태어나는 광주$\cdot$전남지회

  • 대한가족보건복지협회
    • 가정의 벗
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    • v.37 no.11 s.435
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    • pp.24-25
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    • 2004
  • 대한가족보건복지협회 광주.전남지회는 시$\cdot$도민의 삶의질 향상과 건전한 가정생활을 영위 할 수 있도록 가족보건의원과 성폭력상담실, 노인복지센터 등을 운영하고 있다. 가족보건의원에서는 최신의료장비를 갖추고 분만,산부인과,내과,비뇨기과,방사선과,각종 건강 검진사업을 실시하고 있다. 성폭력상담실은 성상담 및 성폭력피해자 성(性)클리닉과 각계층의 성교육도 실시하고 있다. 노인복지센터는 관내 65세 이상 독거노인들을 대상으로 주간보호

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Evaluation of the Size of Emergency Planning Zone for the Korean Standard Nuclear Power Plants (한국표준형 원전에 대한 방사선비상계획구역 범위 평가)

  • Jeon, In-Young;Lee, Jai-Ki
    • Journal of Radiation Protection and Research
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    • v.28 no.3
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    • pp.215-223
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    • 2003
  • Against major release of radioactive material in nuclear power plant, Emergency Planning Zone(EPZ)s are typically established around nuclear power plants to effectively perform the public protective measures. The domestic methodology to determine the size of the EPZ is similar to that of Japan established in 1980, where calculations were based on the conservative accident source term. The objective of this study is to re-evaluate the validity of established EPZ, the area within the radius of $8{\sim}10km$ around domestic nuclear power plants, using the source terms covering full spectrum of accidents obtained from PSA study of ULJIN 3&4. To evaluate the risks of health effects, the computer code MACCS2(MELCOR Accident Consequence Code System2) was used. The result shows that the existing EPZ can reduce the probability of early fatality adequately for most of the source term categories(STCs) except for STC-14 and STC-19. In case of STC-14 and 19, the evacuation distance of 16km and 13km, respectively, are required. These distances can be reduced by improving emergency preparedness since the sensitivity studies for the public protective actions show that the magnitude of early fatality is largely affected by the time delays in notification and evacuation.

The Effects of Cysteamine on the Radiation-Induced Apoptosis (방사선조사에 의해 발생되는 세포고사에 대한 Cysteamine의 효과)

  • Choi, Young-Min;Park, Chang-Gyo;Cho, Heung-Lae;Lee, Hyung-Sik;Hur, Won-Joo
    • Radiation Oncology Journal
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    • v.18 no.3
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    • pp.214-219
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    • 2000
  • Purpose : To Investigate the pathways of radiation induced apoptosls and the effect of cysteamine (${\beta}$-mercaptoethyiamine), as a radioprotector, on it. Materials and Methods : HL-50 ceils were assigned to control, irradiated, and cysteamlne (1 mM, 10mM) pretreated groups. Irradiation was given In a single fraction of 10 Gy (6 MV x-ray) and cysteamine was administered 1 hour before irradiation. The activities of caspase-8 were measured in control and irradiated group to evaluate its relation to the radiation Induced apoptosis. To evaluate the role of cysteamine In radiation Induced apoptosis, the number of viable cells, the expression and activity of caspase-3, and the expression of poly (ADP-ribose) polymerase (PARP) were measured and compared after irradiating the HL-60 celis with cysteamine pretreatment or not. Results : The intraceliular caspase-8 activity, known to be related to the death receptor induced apoptosis, was not affected by irradiation(p>0.05). The number of viable cells began to decrease from 6 hours after irradiation (p>0.05), but the number of viable cells In 1 mM cysteamine pretreated group was not decreased after irradiation and was similar to those in the control group. In caspase-3 analyses, known as apoptosis executioner, its expression was not different but its activity was Increased by irradiation(p>0.05). However, this Increase of activity was suppressed by the pretreatment of 1 mM cysteamine. The cleavage of PARP, thought to be resulted from caspase-3 activation, occurred after irradiation which was attenuated by the pretreatment of 1 mM cysteamine. Conclusion : These results show that radiation induced apoptotic process is somewhat different from death receptor induced one and the pretreatment of 1 mM cysteamine has a tendency to decrease the radiation-induced apoptosis in HL-60 cells.

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Study on the Photoneutrons Produced in 15 MV Medical Linear Accelerators : Comparison of Three-Dimensional Conformal Radiotherapy and Intensity-Modulated Radiotherapy (15 MV 의료용 선형가속기에서 발생되는 광중성자의 선량 평가 - 3차원입체조형방사선치료와 세기조절방사선치료의 비교 -)

  • Yang, Oh-Nam;Lim, Cheong-Hwan
    • Journal of radiological science and technology
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    • v.35 no.4
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    • pp.335-343
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    • 2012
  • Intensity-modulated radiotherapy(IMRT) have the ability to provide better dose conformity and sparing of critical normal tissues than three-dimensional radiotherapy(3DCRT). Especially, with the benefit of health insurance in 2011, its use now increasingly in many modern radiotherapy departments. Also the use of linear accelerator with high-energy photon beams over 10 MV is increasing. As is well known, these linacs have the capacity to produce photonueutrons due to photonuclear reactions in materials with a large atomic number such as the target, flattening filters, collimators, and multi-leaf collimators(MLC). MLC-based IMRT treatments increase the monitor units and the probability of production of photoneutrons from photon-induced nuclear reactions. The purpose of this study is to quantitatively evaluate the dose of photoneutrons produced from 3DCRT and IMRT technique for Rando phantom in cervical cancer. We performed the treatment plans with 3DCRT and IMRT technique using Rando phantom for treatment of cervical cancer. An Rando phantom placed on the couch in the supine position was irradiated using 15 MV photon beams. Optically stimulated luminescence dosimeters(OSLD) were attached to 4 different locations (abdomen, chest, head and neck, eyes) and from center of field size and measured 5 times each of locations. Measured neutron dose from IMRT technique increased by 9.0, 8.6, 8.8, and 14 times than 3DCRT technique for abdomen, chest, head and neck, and eyes, respectively. When using IMRT with 15 MV photonbeams, the photoneutrons contributed a significant portion on out-of-field. It is difficult to prevent high energy photon beams to produce the phtoneutrons due to physical properties, if necessary, It is difficult to prevent high energy photon beams to produce the phtoneutrons due to physical properties, if necessary, it is need to provide the additional safe shielding on a linear accelerator and should therefore reduce the out-of-field dose.