• Journal of the Korean Society of Radiology
• /
• v.13 no.3
• /
• pp.333-338
• /
• 2019

In the field of radiotherapy, the Quality Assurance(QA) procedure to verify the safety of treatment is considered to be very important. However, due to various problems of the conventional dosimeters used for the QA, researches on these dosimeters have been actively carried out to replace them. In this study, to maximize the sensitivity by visible light(VL) emitted from phosphors, blended hybrid sensors were fabricated by blending various weight percent(wt%) of $Gd_2O_2S:Tb$ which is a phosphor with excellent fluorescence efficiency into $PbI_2$. Then, the electrical properties to high energy radiation from the blended sensors and the pure $PbI_2$ sensor were compared and evaluated. As a result of the sensitivity evaluation, the sensor of 3wt% showed the highest value with more than 40% difference from the other sensors, and gradual decreasing in sensitivity was observed with increasing wt% except for the sensor of 3wt%. Also, in the reproducibility evaluation, the pure $PbI_2$ sensor exhibited a large variation in coefficient of variation(CV)>0.015, while all the blended sensors showed CV<0.015.

• Journal of the Korean Society of Radiology
• /
• v.10 no.6
• /
• pp.427-433
• /
• 2016

Recently increased use of high energy x-ray in radiation therapy, so therapeutic efficiency of tumors that located deep part also increased. However, photoneutron is problem which is generated caused by photoneuclear reaction. Photoneutron is continually required management because of that is more harmful than photon. In this regard, the study utilizing simulation of the Monte Carlo method is actively progress about photoneutron but measure is deficient. So this study was analyzed the correlation between the measured photon and photoneutron by radiation measurement device. As a result, photons were reduced when distance is farther and field size is smaller. But photoneutron were increased when field size is smaller and increased to a certain distance then reduced.

• The Korean Society of Law and Medicine
• /
• v.23 no.2
• /
• pp.97-118
• /
• 2022

The use of diagnostic radiation in medical institutions is rapidly increasing. Accordingly, the collective effective dose is on the rise every year. Therefore, it is necessary to reduce the radiation exposure of the person undergoing the radiation examination as low as reasonably achievable. And we must establish a legal system to perform the safe management of radiation for diagnosis efficiently. In this way, I went over the problems of the Act and Subordinate Statutes regarding radiation safety management for diagnosis. As a result, the main contents are as follows. First, in the 「Medical Service Act」, there is no basis for the Safety Inspection Institute of Radiation and Radiation Exposure Measuring Institutes. And there are no provisions concerning delegation of administrative disposition. Therefore, it is necessary to secure legal justification by providing the basis for the Safety Inspection Institute of Radiation along with Radiation Exposure Measuring Institutes and the basis for administrative dispositions against these institutions in the 「Medical Service Act」. Second, the 「Rules on the Installation and Operation of Special Medical Equipment 」 should be integrated with the 「Rules on the Safety Management of Radiation Generators for Diagnostics」 to unify administrative procedures such as reporting for radiation special medical equipment for diagnosis. Third, in the case of violating the diagnostic radiation safety management standards in the 「Rules on the Safety Management of Radiation Generators for Diagnostics」, it is necessary to supplement the insufficient sanctions such as administrative disposition. Fourth, regulating diagnostic radiation and therapeutic radiation used in medical institutions with the dual legal system of the 「Medical Act」 and the 「Nuclear Safety Act」 is not efficient in the safety management of diagnostic radiation. Therefore, it is necessary to uniformly regulate diagnostic radiation and all medical radiation, including therapeutic radiation and nuclear medicine, in the 「Medical Service Act」 system.

• Proceedings of the KIPE Conference
• /
• 2019.07a
• /
• pp.242-244
• /
• 2019

본 논문은 방사선 치료에 사용되는 선형 전자가속기(LINAC)의 작동 원리와 구성 등 의료용 LINAC의 전반을 다룬다. 의료용 LINAC은 전자총에서 발사된 전자를 가속기 튜브 내에서 가속시켜 전자빔을 발생시키고, 이러한 전자빔을 금속 표적에 충돌시켜 발생한 X 선을 인체에 조사하는 원리이다. 최근에는 O-arm, C-arm 등 3-D 촬영을 위한 치료기가 개발됨에 따라, 의료용 LINAC의 전자총, 마그네트론 등을 구동하는데 사용되는 고전압 전원장치 또한 소형화와 고밀도화가 요구되는 추세이다. 본 논문에서는 마그네트론 구동을 위한 고밀도 40kV/100A 음극성 펄스 모듈레이터와 정전압 정전류 제어 및 50kV 절연이 가능한 히터 전원장치를 설계 및 제작하였으며, 9.3GHz, 1.7MW X-Band 마그네트론 연계실험을 통해 고효율 고신뢰성의 동작을 확인하였다.

• Radiation Oncology Journal
• /
• v.15 no.2
• /
• pp.121-128
• /
• 1997

Purpose : To evaluate the effect of postoperative adjuvant radiation therapy and chemotherapy on the survival, pattern of failure and complication for locally advanced rectal carcinoma Materials and Methods : From October 1992 to September 1995, twenty eight patients with rectal carcinoma were treated by postoperative adjuvant radiation therapy and chemotherapy Radiation therapy was delivered with 6MV and 15MV linear accelerator, 180c0y fractions 5 day per week. Total radiation doses were 5040cGy in $B_{2+3}$ and 5580cGy in $C_{2+3}$. Within 4 weeks after radical surgery. 5-FU$(400mg/m^2/day)\;and\;Leucovorin(20mg/m^2/day)$ were administered by intravenous injection for 4 days during the first and fifth week of radiation therapy. The median follow up was 19 months with a range 2 to 47 months. Results : The 2 year overall survival and disease free survival rates were $78.6\%\;and\;70.8\%$, respectively. The 2 year overall survival was $93.0\%\;in\;B_{2+3}$ and $76.2\%\;in\;C_{2+3}$(p=0.11) The 2 year disease free survival was $79.4\%\;in\;B_{2+3}\;and\;69.2\%\;in\;C_{2+3}(p=0.13)$. The overall failure rate was $21.42\%$(6/28) including $10.72\%$(3/28) locoregional recurrence, $3.62\%$(1/28) distant metastasis and $7.12\%$(2/28) locoregional recurrence with distant metastasis. The overall locoregional recurrence rate was $17.92\%$(5/28). The 2 year locoregional recurrence rates were $13.32\%(2/15)\;and\;23.12\%$(3/13) for respectively for $B_{2+3}\;and\;C_{2+3}$ The difference between the locoregional recurrence of $B_{2+3}\;and\;C_{2+3}$ patients was not significant(p=0.07). Complications developed in 13 patients$(46.42\%)$, including 8 dermatitis, 7 loose stool, 6 leukopenia, 4 tenesmus, 2 diarrhea. In Univariate analysis, there was no statistically significant factor except for tumor grade in locoregional recurrence, disease free survival and overall survival rate(p=0.04, 0.05, 0.04). Conclusion : This study sugges1s that postoperative adjuvant radiation therapy and chemotherapy is effective in patients with locally advanced rectal cancer. Therefore these results need to be confirmed with a long term follow-up and larger number of patients with the further clinical trials including prospective controlled studies.

• Journal of the Korean Society of Radiology
• /
• v.10 no.3
• /
• pp.195-200
• /
• 2016

Acute promyelocytic leukemia(APL) is not just the poor grades of treating a type of blood cancer hayeoteul combination with chemotherapy despite concurrent radiation therapy are known to exhibit a greater effect and also works on normal cells to result in side effects. In this study, when after treatment with gamma rays, such as $TNF-{\alpha}$ in order to reduce these side effects was confirmed how affected the cell death of normal cells and cancer cells. HL-60 cells were used as the APL cell line HL-60 cells were differentiated with DMSO for treatment are shown the properties of normal granulocytes was used as a control group. As a result, HL-60 cells treated with $TNF-{\alpha}$ and gamma rays with only showed a cytotoxic effect by inducing the apoptosis cells were put to death. Consequently, $TNF-{\alpha}$ is thought to active substances that can increase the efficiency of cancer treatment to increase the removal of cancer cells when used with low-density gamma-ray treatment in order to eliminate the side effects of chemotherapy.

• Progress in Medical Physics
• /
• v.15 no.4
• /
• pp.179-185
• /
• 2004

To deal with tumor motion from respiration is one of the important issues for the advanced treatment techniques, such as the intensity modulated radiation therapy (IMRT), the image guided radiation therapy (IGRT), the three dimensional conformal therapy (3D-CRT) and the Cyber Knife. Studies including the active breath control (ABC) and the gated radiation therapy have been reported. Authors have developed the device for reducing the respiration effects and the diaphragm motions with this device were observed to determined the effectiveness of the device. The device consists of four belts to immobilize diaphragm motion and the vacuum cushion. Diaphragm motions without and with device were monitored fluoroscopically. Diaphragm motion ranges were found to be 1.14 ～ 3.14 cm (average 2.14 cm) without the device and 0.72～1.95 cm (average 1.16 cm) with the device. The motion ranges were decreased 20 ～ 68.4% (average 44.9%.) However, the respiration cycle was increased from 4.4 seconds to 3.7 seconds. The CTV-PTV margin could be decreased significantly with the device developed in this study, which may be applied to the treatments of the tumor sited diaphragm region.

• The Journal of Korean Society for Radiation Therapy
• /
• v.26 no.2
• /
• pp.281-287
• /
• 2014

Purpose : The purpose of this study is to compare the plan quality of volumetric-modulated arc therapy (VMAT) and intensity-modulated radiation therapy (IMRT) for the treatment of orbital lymphoma. IMRT, partial single arc(SA) and partial-double arc(DA) VMAT plans for four patients with orbital lymphoma treated at our institution were used for this study. Conformity Index(CI), Paddick's Conformity Index(PCI) and Homogeneity Index(HI) of planning target volume(PTV) were used to evaluate dosimetric quality of each plan. The Monitor Unit (MU), treatment time and dose of ipsilateral lens from each type of plan were measured for comparison. Materials and Methods : The CI of PTV for IMRT, SA and DA were measured as 0.88, 0.86, 0.92. The PCI of DA was the lowest as 1.33. Also HI of DA was the lowest in measured plans as 1.15. Mean dose of lens, lacrimal gland, optic chiasm, the opposite optic nerve and both orbit was analyzed with V30, V20, V10, V5. The result showed that the lowest dose in IMRT highest in SA in opposite lens, lacrimal gland, optic nerve, orbit. Results : Treatment time and average MU of IMRT was about three times higher than SA. Conclusion : Considering the superior plan quality as well as the delivery efficiency of VMAT compared with that of IMRT, VMAT may be the preferred modality for treating orbital lymphoma.

• Journal of the Korean Society of Radiology
• /
• v.9 no.4
• /
• pp.249-255
• /
• 2015

In this study, through the additional information of the PET / CT images by utilizing the basic data of TPS clinical application on the basis of the image re-forming synthetic function, the True-D technology and MIM software for continued research and development in combination, based on the combination-work between the respective images, reducing the time and cost of useful reading in clinical wide use of image width, efficient, effective tool for tumor targeting at diagnosis and radiation therapy by use as, by using the precise therapeutic effect determination, the time taken to read in the clinical, unnecessary and expect to a can reduce the additional examination by the creation of tumor patients read reports and PACS such asWe expect to be utilized for compatibility development with other software to evaluate the performance of PET / CT equipment.

• The Journal of Korean Society for Radiation Therapy
• /
• v.13 no.1
• /
• pp.47-50
• /
• 2001

Purpose : 체내에서 optimal한 dose distribution을 얻기 위해 도입된 IMRT를 시행할 때 사용하는 MLC는 기계특성상 장기적인 check와 교정을 요한다. 또한 MLC는 static하지 않고 dynamic하기 때문에 leaf position의 실제 위치가 매우 중요하다. MLC QA를 위해 QA 소요시간 및 노력이 많이 MLC position check 요구되는 불편이 있어, 삼성서울 병원에서 필름을 이용한 MLC position check device를 제작하여 간편하게 사용하고 그 우수성에 대해 결과를 보고하고자 한다. Materials and Method : MLC position을 check하기위해 사각형 의 device(acryl:$40{\times}40{\times}5cm$)를 제작하였다. position check device의 정확도를 위해 표면에 real scale 표시용으로 Pb marker를 2cm 간격으로 부착하였다. MLC QA film은 마주보는 (opposite) MLC leaf의 간격이 4mm로 set up한 상태에서 double exposure하여 marker를 이용하여 오차를 분석하였다. MLC position check device의 효율성을 평가하기위해 6MV photon으로 10번 반복 실험을 실시하여 MLC leaf의 평균오차를 조사하고 조사에 걸린 시간을 비교하여 유용성을 평가하였다. Results : 실험결과 MLC leaf의 평균오차를 조사하고 조사에 걸린 시간을 비교하여 유용성을 평가하였다. 범위는 1.45mm였고, 최소 오차는 0.34mm로 나타났다. 1회 조사에 걸린 시간은 평균적으로 약 30분 정도 소요되었다. MLC position check device의 효율성을 평가한 결과오차의 반복성은 관찰되지 않았다. Conclusion : MLC leaf position의 정기적인 check와 교정을 위해 본원에서는 주1회 정기 position error를 check하고 있으며, 평균 월1회 교정을 한다. 본 실험을 통해 MLC position check device를 사용하여 leaf 오차가 2mm이하의 만족할 만한 결과를 얻었다. 또한 MLC position check device를 사용하면 짧은 시간에 모든 leaf의 position error를 쉽게 측정할 수 있고 한 장의 필름으로 모든 결과를 평가할 수 있어 경제성 및 업무의 효율성도 높일 수 있었다.