• 대한방사선방어학회:학술대회논문집
• /
• 2011.04a
• /
• pp.72-73
• /
• 2011

• Journal of Life Science
• /
• v.17 no.5 s.85
• /
• pp.664-670
• /
• 2007

The propolis is natural product produced by honeybees and is known to have many biologically useful properties such as anti-microbial, anti-oxidative and anti-tumorigenic activity. However, its radio-protective property has not been well studied. To investigate radio-protective effect of propolis on mouse testis, mice were supplemented with propolis after 5 Gy irradiation. The histological changes of testis were detected by TEM. The results indicate that propolis may protect tissue deformation which is induced by 5 Gy of ionizing radiation. Furthermore, to elucidate the potential molecular mechanisms involved in radio-protective property of propolis, we performed microarray experiments using oligo DNA microarray. We found 65 up-regulated genes and 224 down-regulated genes, whose expression levels were affected more than 2-fold by propolis treatment in mice irradiated at 5 Gy. We confirmed microarray data with reverse transcription-PCR using gene specific primers. The results of RT-PCR are highly correlated with those of microarray. These results may help understanding molecular mechanisms of radioprotective effects by propolis in mouse model.

• The Journal of the Korea Contents Association
• /
• v.16 no.10
• /
• pp.563-572
• /
• 2016

The purpose of this study was to examine the knowledge, attitude and educational needs of radiation protection among nursing students and nurses, because it is needed to raise awareness of the importance of radiation protection. The participants in this study were 274 including 135 registered nurses on bachelor's degree course who had experience of the operating room practice and 139 nursing students. The questionnaire consisted of 45 items including knowledge, attitude, and educational needs of radiation protection. The findings of the study suggest that safe management education was insufficient for protection of radiation. Though, educational needs and intention of involvement were high, the respondents who were more knowledgeable about radiation protection took a better attitude of radiation protection. A radiation protection course development is needed according to educational needs. Nurses have to get a chance to receive education outside the hospital or be provided with a radiation protection program as internal education. Also, radiation educational experts and various visual and auditory materials are needed to promote effectiveness of education.

• 대한방사선방어학회:학술대회논문집
• /
• 2011.11a
• /
• pp.138-139
• /
• 2011

• 대한방사선방어학회:학술대회논문집
• /
• 2011.04a
• /
• pp.116-117
• /
• 2011

• 대한방사선방어학회:학술대회논문집
• /
• 2011.04a
• /
• pp.60-61
• /
• 2011

• 대한방사선방어학회:학술대회논문집
• /
• 2011.04a
• /
• pp.58-59
• /
• 2011

• 대한방사선방어학회:학술대회논문집
• /
• 2009.11a
• /
• pp.200-201
• /
• 2009

• 대한방사선방어학회:학술대회논문집
• /
• 2011.04a
• /
• pp.74-75
• /
• 2011

• The Journal of the Korea Contents Association
• /
• v.9 no.7
• /
• pp.211-217
• /
• 2009

In order to find out the radioprotective effect of algin-oligosaccharide, this study, with a mouse of which whole body irradiated by 3 Gy radiation once, measured nitric oxide. In nitric oxide test for observing the reaction of cell inflammation, nitric oxide showed decreased in the irradiation control group, while 3 day's treatment group with algin-oligosaccharide before or after irradiation indicated higher than the irradiation control group, especially showed big difference in 3 day's treatment group before irradiation (P<0.001). Consequently, this study inquired into the fact that algin-oligosaccharide with superior antioxidant activity performed radiation protection by increasing promotion of nitric oxide generation and confirmed that natural product with less chemical toxicity was able to be applied as radioprotector.