• Title/Summary/Keyword: 방사선감수성

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Comparative Effects of Gamma Irradiation and Methyl Bromide Fumigation on Disinfestation and Physicochemical Properties of Mung Bean (감마선과 Methyl Bromide 처리가 녹두의 살충 및 이화학적 특성에 미치는 영향)

  • 노미정;권중호;권용정;허은엽;권용순;변명우
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.30 no.3
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    • pp.444-449
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    • 2001
  • Comparative effects of gamma irradiation and methyl bromide (MeBr) fumigation on disinfestation and physicochemical attributes of mung bean were investigated. Insects in domestic mung bean were identified to be Collosobruchus chinensis Linne. Ina disinfestation test, MeBr showed 100% disinfestation effect on Larva and adult at 5th day after treatments, while irradiation dose above 3 kGy was effective for disinfesting all larva at that time. Adults were more sensitive to radiation than larva. Around 1 kGy was enough to control larva and adult in mung bean following 10 to 15 days of irradiation. In physicochemical properties of treated sampels, nitrogen solubility, TBA value, amino acid and fatty acid compositions were not different among the control, 2.5 kGy-irradiated and MeBr-fumigated samples. MeBr fumigation caused the decrease in lightness (Hunter's L value) and the increase in redness (a value) and yellowness (b value), thereby resulting in overall color difference (${\Delta}E$) in a noticeable level (NBS 2.61~2.94).

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Pyometra and Serosal Inclusion Cysts of the Uterus in a Bitch (개에서 발생한 자궁축농증과 장막성 낭포 1예)

  • Lee, Jun-Am;Kim, Ill-Hwa;Jang, Dong-Woo;Mo, In-Pil;Kang, Hyun-Gu
    • Journal of Veterinary Clinics
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    • v.30 no.4
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    • pp.305-309
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    • 2013
  • Pyometra is a diestrual, chronic disease process with acute manifestations in the adult, ovary-intact bitch. Serosal inclusion cysts develop during postpartum involution as mesothelium becomes trapped during rapid uterine contraction. A 10-year-old golden retriever bitch presented with lethargy, anorexia, tachypnea, abdominal distention, and abnormal vaginal discharge. Radiographic, ultrasound, and laboratory examinations were performed. On ultrasound examination, the uterus was distended by fluid containing echogenic "snow storm" particles; cystic structures containing anechoic fluid were found adjacent to the body of the uterus. Leukocytosis, neutrophilia, and anemia were diagnosed by a complete blood cell count. The initial diagnosis was pyometra, and an ovariohysterectomy was performed. Macroscopically, the uterine body and horns were expanded and partially adhered to the abdominal wall; numerous cysts containing clear fluid protruded over the entire surface of the uterus. Escherichia coli that was sensitive to enrofloxacin, was cultured from the lumen of the uterus. Histopathological assessment confirmed a final diagnosis of pyometra and serosal inclusion cysts of the uterus.

Quality Stability of Spinach Powder As Influenced by Microbial Decontamination Treatment (시금치 분말의 품질안정성에 대한 살균처리의 영향)

  • Kwon, Joong-Ho;Byun, Myung-Woo;Cho, Han-Ok;Choi, Jong-Uck
    • Korean Journal of Food Science and Technology
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    • v.26 no.2
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    • pp.167-171
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    • 1994
  • With a view to improving microbiological quality of spinach powder which is currently used for convenience food production, comparative efficacy of ethylene oxide(EO) fumigation and gamma irradiation was investigated by determining microbial populations and physicochemical quality for treated samples. Spinach powder was contaminated with various microorganisms ranging from $10^{2}/g\;to\;10^{4}/g$, which composed of thermophiles, acid tolerant bacteria, fungi, coliforms, etc. Microorganisms contaminated were destroyed up to undetected levels by gamma irradiation at below 7 kGy. showing the radiosensitivity $D_{10}$ 2.93 kGy on total aerobic bacteria. Ethylene oxide fumigation, however. was found unsatisfactory for physicochemical quality as well as microbial decontamination of the sample. It has been generally observed that influence of optimum-dose range of irradiation on the physicochemical qualities was insignificant, which was proved in the organoleptic evaluations on the stored sample.

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Elimination of Microorganisms Contaminated in Red Ginseng Powder by Irradiation Processing (감마선 조사를 이용한 홍삼분말의 오염미생물 제거)

  • Yook, Hong-Sun;Kim, Seong-Ai;Byun, Myung-Woo;Kwon, Joong-Ho
    • Korean Journal of Food Science and Technology
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    • v.28 no.2
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    • pp.366-370
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    • 1996
  • Gamma irradiation was applied to red ginseng powder for improving its hygienic quality 7.5 kGy of gamma irradiation completely eliminated the microorganisms contaminated in red ginseng powder. And there was no growth of microorganisms after six months of storage at room temperature. The molds isolated from red ginseng powder were identified as Pen. commune, Asp. niger, Asp. versicolor and Asp. Unguis, the conidia of which showed the decimal reduction dose ($D_{10}$ value) of 0.37-0.50 kGy, 0.24-0.31 kGy, 0.25-0.36 kGy and 0.28-0.41 kGy and inactivation factor of 5.0-6.5, 7.4-9.3, 6.5-9.1 and 6.1-8.4, respectively The radiosensitivity of identified molds' conidia decreased in medium containing red ginseng extract.

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Radioresistance of Acorus calamus to Gamma Ray Irradiation

  • Lee, Ja-Hyun;Kang, Si-Yong;Lee, Geung-Joo;Lee, Seong-Gene;Kim, Sun-Kook;Han, Tae-Ho
    • FLOWER RESEARCH JOURNAL
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    • v.19 no.2
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    • pp.119-125
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    • 2011
  • Acorus calamus is an indigenous hydrophyte used as phytoremediation and water purification as well as medicinal herb. Irradiation of gamma ray was performed to investigate the effect on radioresistance of A. calamus on in vitro. Various doses (20-500 Gy) of gamma rays were irradiated to in vitro plantlets. The effect of irradiation was studied on survival rate, shoot formation and growth rate. The survival and multiplication rate was remarkably decreased with the increase of radiation dose. The growth of plantlets was significantly increased in comparison to the control at low doses. The hermetic effect of radiation was appeared in A. calamus. It was significantly decreased or interrupted above 250 Gy. The mean 50% lethal dose ($LD_{50}$) was extremely high as 240 Gy. We conclude that A. calamus had remarkably high radioresistance compared with other plant species.

Enhanced Radiosensitivity of Tumor Cells Treated with Vanadate in Vitro (Vanadate 처리가 종양세포의 방사선 감수성에 미치는 영향)

  • Lee, Myung-Za;Lee, Won-Young
    • Radiation Oncology Journal
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    • v.12 no.2
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    • pp.129-141
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    • 1994
  • Intracellular ions which have a major role in cellular function have been reported to affect repair of radiation damage. Recently it has been reported that ouabain sensitizes A549 tumor cellls but not CCL-120 normal cells to radiation. Ouabain inhibits the $Na^+-K^+$-pump rapidly thus it increases intracellular Na concentration, Vanadate which is distributed extensively in almost all living organisms is known to be a $Na^+-K^+$-ATPase inhibitors, This study was performed to see any change in radiosensitivity of tumor cell by vanadate and any role of $Na^+-K^+$ATPase in radiosensitization. Experiments have been carried out by pretreatment with vanadate in human cell line(A549, JMG) and mouse cell line(L1210, spleen). For the cell survival MTT assay was performed for A549 and JMC cells and frypan blue dye exclusion test for L120, and spleen cells. Measurements of $Na^+-K^+$-ATPase activity in control, vanadate treated cell, radiation treated cell (9 Gy for A549 and JMG, 2 Gy for L1201, spleen), and combined $10^{-6}M$ vanadate and radiation treated cells were done. The results were summerized as fellows. 1. L1210 cell was most radiosensitive, and spleen cell and JMG cell were intermediate, and A549 cell was least radiosensitive. 2. Mininum or no cytotoxicity was seen with vanadate below concentration of $10^{-6}M$. 3. In A549 cells there was a little change in radiosensitivity with treatment of vanadate. However radiation sensitization was shown in low dose level of radiation i. e. 2- Gy. In JMG cells no change in radiosensitivity was noted. Both L1210 and spleen cell had radiosensitization but change was greater in tumor cell. 4. $Na^+-K^+$-ATPase activity was inhibited significantly in tumor cell by treatment of vanadate. 5. Radiaiton itself inhibited $Na^+-K^+$-ATPase activity of tumor cell with high $Na^+-K^+$-ATPase concention. Increase in radiosensitivity by vanadate was closely associated with orginal $Na^+-K^+$-ATPase contents. From the above results vanadate had little cytotoxicity and it sensitized tumor cells to radiation. Inhibitory effect of vanadate on $Na^+-K^+$-ATPase activity might be one of the contributing factors for radiosensitization to tumor cells which has greater enzyme activity than that of normal cell. It was suggested vanadate could be used as a potential radiosensitizer for tumor cells.

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Research on Dose Reduction During Computed Tomography Scanning by CARE kV System and Bismuth (전산화 단층검사 시 Bismuth와 CARE kV System을 이용한 선량 저감화에 대한 연구)

  • Kwak, Yeong-Gon;Kim, Chong-Yeal;Jeong, Seong-Pyo
    • The Journal of the Korea Contents Association
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    • v.14 no.8
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    • pp.233-242
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    • 2014
  • The purpose of this study is to compare the reduction of the dose radioactivity by CARE kV with that of the Bismuth shielding. First, CT was performed with transparent materials, including a Bismuth shielder which is a well-known material for decreasing the dose of radiation. Moreover, we have estimated and compared the affects of the reduction of dose on eye lens, thyroid, breast and genitals. These steps aim to compare reactions with and without the application of the Rando phantom with PLD as well as with CARE kV or not. As a result, during the Brain angio scan, the dose of CARE kV set inspection test methods showed the least dose. Depending on whether we use CARE kV, which showed the effect of dose reduction by 63%. During the Carotid angio scan, the dose was increased by 13% by how to set CARE kV+Bismuth. During the Cardiac angio scan, which showed the effect of dose reduction by 31% by how to set CARE kV+Bismuth. During the Lower extremity angio scan, the dose was measured least by how to set up the whole Bismuth. Compared with CARE kV set of test methods, which showed the effect of dose reduction by 9%.

Assesment Of Image Quality in the Abdominal Magnetic Resonance Imaging: Comparison with 1.5 T and 3.0 T (복부 자기공명영상에서 영상의 질 평가: 1.5 T 와 3.0 T 비교)

  • Goo, Eun-Hoe
    • Journal of the Korean Society of Radiology
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    • v.10 no.5
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    • pp.367-373
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    • 2016
  • This study conducted an analysis to compare the differences in the properties of the magnetic field and the generation of artifacts because of the difference in the magnetic field between 1.5 T equipment and 3.0 T equipment, centering around four types of pulse sequences, mainly applied to the abdominal Magnetic Resonance Imaging (MRI). With data on 500 persons transmitted to the PACS, this study analyzed the SNR value, quantitatively and carried out a qualitative evaluation, dividing MSA, CSA, and DA into three steps. As a result of the quantitative evaluation, the SNR value was significantly higher in the 1.5 T equipment; however, there was a factor deteriorating the image quality, too, as artifacts were generated in the images. The 1.5 T equipment generated fewer artifacts than the 3.0 T equipment did, so it could compensate the image quality for 3.0 T. In conclusion, based on these findings, this study could understand the differences in the properties of the magnetic field and the generation of artifacts occurring because of the difference in the magnetic field and could provide a measure for them. This study would be guidelines for MRI users who directly examine the patients in abdominal MRI using the two types of equipment in the clinical setting in the future.

Photon Energy Dependence of the Sensitivity of LiF TLDs Loaded with Thin Material (얇은 박막을 얹은 TLD 반응감도의 광자 에너지에 대한 의존성)

  • Min Byongim J;Kim Sookil;Loh John J.K;Cho Young Kap
    • Radiation Oncology Journal
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    • v.17 no.3
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    • pp.256-260
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    • 1999
  • Purpose : An investigation has been carried out on the factors which affect the response reading of thermoluminescent dosimeters (TLD-100) loaded with thin material in high energy Photon. The aim of the study was to assess the energy response of TLD-100 to the therapeutic ranges of photon beam. Materials and Methods : In this technique, TLD-100 (abbreviated as TLD) chips and three different thin material (Tin, Gold, and Tissue equivalent plastic plate) which mounted on the TLD chip were used in the clinical photon beam. The thickness of each metal plates was 0.1 mm and TE plastic plate was 1 mm thick. These compared with the photon energy dependence of the sensitivities of TLD (normal chip), TLD loaded with Tin or Gold plate, for the photon energy range 6 MV to 15 MV, which was of interest in radiotherapy. Results : The enhancement of surface dose in the TLD with metal plate was clearly detected. The TLD chips with a Gold plate was found to larger response by a factor of 1.83 in 10 MV photon beam with respect to normal chip. The sensitivity of TLD loaded with Tin was less than that for normal TLD and TLD loaded with Gold. The relative sensitivity of TLD loaded with metal has little energy dependence. Conclusion : The good stability and linearity with respect to monitor units of TLD loaded with metal were demonstrated by relative measurements in high energy Photon ($6\~15$ MV) beams. The TLD laminated with metals embedded system in solid water phantom is a suitable detector for relative dose measurements in a small beam size and surface dose.

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A Case of Mycobacterium Abscessus Pneumonia in a Patient with Systemic Lupus Erythematosus (전신성 홍반성 낭창 환자에서 발생한 Mycobacterium abscessus에 의한 폐렴 1예)

  • Yim, Jae-Joon;Oh, Myoung-Don;Yoo, Chul-Gyu;Song, Yeong-Wook;Kim, Young-Whan;Seo, Jung-Wook;Han, Sung-Gu;Choe, Kang-Won;Shim, Young-Soo
    • Tuberculosis and Respiratory Diseases
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    • v.46 no.1
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    • pp.96-102
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    • 1999
  • A 40-year-old female presented with fever and cough which had lasted for 3 months. Three years previously systemic lupus erythematosus had been diagnosed, and at that time 10mg of prednisone per day was prescribed. Crackles were heard at the base of the lung and her chest roentgenogram revealed diffuse infitrates in both lower lung fields. Despite of empirical antibiotics and antituberculous medication consisting of isoniczid, rifampicin and ethambutol, the patients condition deteriorated. We performed open lung biosy and numerous nodules with necrosis as well as acid fast bacilli were observed. After biochemical tests and sequencing, the organism was identified as Mycobacterium abscessus. The patient was treated with imipenem and amikacin ; patient's condition, as indicated by both symptoms and roentogenogram, subsequently improved.

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