• The Journal of the Korea Contents Association
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• v.11 no.5
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• pp.84-92
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• 2011

The automated segmentation technique of cell region in Bio Images helps biologists understand complex functions of cells. It is mightly important in that it can process the analysis of cells automatically which has been done manually before. The conventional methods for segmentation of cell and nuclei from multi-channel images consist of two steps. In the first step nuclei are extracted from DNA channel, and used as initial contour for the second step. In the second step cytoplasm are segmented from Actin channel by using Active Contour model based on intensity. However, conventional studies have some limitation that they let the cell segmentation performance fall by not considering inhomogeneous intensity problem in cell images. Therefore, the paper consider correlation between DNA and Actin channel, and then proposes the preprocessing algorithm by which the brightness of cell inside in Actin channel can be compensated homogeneously by using DNA channel information. Experiment result show that the proposed preprocessing method improves the cell segmentation performance compared to the conventional method.

• The KIPS Transactions:PartB
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• v.10B no.5
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• pp.521-526
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• 2003

In this paper, we propose a geometric active contour model based on intensity information and curve evolution for detecting region boundaries. We put boundary extraction problem as the minimization of the difference between the average intensity of the region and the intensity of the expanding closed curves. We used level set theory to implement the curve evolution for optimal solution. It offered much more freedom in the initial curve position than a general active contour model. Our methods could detect regions whose boundaries are not necessarily defiened by gradient compared to general edge based methods and detect multiple boundaries at the same time. We could improve the result by using anisotropic diffusion filter in image preprocessing. The performance of our model was demonstrated on several data sets like CT and MRI medical images.

• Journal of Korea Multimedia Society
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• v.9 no.9
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• pp.1150-1159
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• 2006

This paper proposed a curve progress control function of the area base instead of the existing edge indication function, in order to detect the brain ventricle area by utilizing a geodesic active contour model. The proposed curve progress control function is very effective in detecting the brain ventricle area and this function is based on the average brightness of the brain ventricle area which appears brighter in MRI images. Compared numerically by using various measures, the proposed method in this paper can detect brain ventricle areas better than the existing method. By examining images of normal and diseased brain's images by brain tumor, we compared the several brain ventricle detection algorithms with proposed method visually and verified the effectiveness of the proposed method.

• Journal of KIISE:Software and Applications
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• v.27 no.7
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• pp.731-741
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• 2000

This paper proposes a method to detect a facial region and extract facial features which is crucial for visual recognition of human faces. In this paper, we extract the MER(Minimum Enclosing Rectangle) of a face and facial components using projection analysis on both edge image and binary image. We use an active contour model(snakes) for extraction of the contours of eye, mouth, eyebrow, and face in order to reflect the individual differences of facial shapes and converge quickly. The determination of initial contour is very important for the performance of snakes. Particularly, we detect Minimum Enclosing Rectangle(MER) of facial components and then determine initial contours using general shape of facial components within the boundary of the obtained MER. We obtained experimental results to show that MER extraction of the eye, mouth, and face was performed successfully. But in the case of images with bright eyebrow, MER extraction of eyebrow was performed poorly. We obtained good contour extraction with the individual differences of facial shapes. Particularly, in the eye contour extraction, we combined edges by first order derivative operator and zero crossings by second order derivative operator in designing energy function of snakes, and we achieved good eye contours. For the face contour extraction, we used both edges and grey level intensity of pixels in designing of energy function. Good face contours were extracted as well.