• Title/Summary/Keyword: 반확산

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Preparation of Dextran Microparticles by Using the SAS Process (초임계 반용매 재결정 공정을 이용한 Dextran 입자의 제조)

  • Kang, Dong-Yuk;Min, Byoung-Jun;Rho, Seon-Gyun;Kang, Choon-Hyoung
    • Korean Chemical Engineering Research
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    • v.46 no.5
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    • pp.958-964
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    • 2008
  • In this work, micro-sized dextran particles, which have recently been focused as one of the candidate materials for the Drug Delivery System(DDS), were prepared by means of the Supercritical Antisolvent (SAS) process with $CO_2$. With dimethyl sulfoxide(DMSO) as the solvent, effects of the operating variables such as temperature (308.15~323.15 K), pressure(90~130 bar), solute concentration(10~20 mg/ml), and the molecular weight of the solute(Mw=37,500, 450,000) on the size and morphology of the resulting particles were thoroughly observed. The higher solute concentration led to the larger particles, however, the injection velocity of the solution and pressure did not show significant effects on the resulting particle size. With dextran of the lower molecular weight, the smallest particles were obtained at 313.15 K. On the other hand, the size of the particles from the high molecular weight dextran ranged between $0.1{\sim}0.5{\mu}m$ with an incremental effect of the temperature and pressure. For the solute concentration of 5 mg/ml, the lower molecular weight dextran did not form discrete particles while aggregation of the particles appeared when the solute concentration exceeded 15 mg/ml for the higher molecular weight dextran. It is believed that if the solute concentration is too low, the degree of the supersaturation in the recrystallization chamber would not be sufficient for initiation of the nucleation and growth mechanism. Instead, the spinodal decomposition mechanism leads to formation of the island-like phase separation which appears similar to aggregation of the discrete particles. This effect would be more pronounced for the smaller molecular weight polymer system due to the narrower phase-splitting region.

A Study on the Effects of Purchaser's Cognitive Dissonance on their Re-purchase and Dissatisfaction in Online Shopping Malls (온라인쇼핑몰에서 구매고객의 인지부조화가 불만족 및 재구매에 미치는 영향에 관한 연구 - e-CRM 구성요소 중 e-Community를 중심으로 -)

  • Lee, D.-Gyu;Ro, Tae-Bum
    • CRM연구
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    • v.2 no.2
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    • pp.71-88
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    • 2009
  • The purpose of this thesis is to examine the effects of e-CRM activities by the internet shopping mall companies on the purchase activities of purchase customers and the potential customers. The internet shopping companies utilize e-CRM to systematically identify customers' varying demands, and to utilize the results as marketing tools, thus producing a significant effect on the potential customers by generating customer feedback through e-Community. Contrary to their intention, however, cognitive dissonance can occur through e-Community, which may lead to customers' complaints. If these complaints are not properly managed and settled in a timely manner, they can be transferred to other potential customers, and the conformity phenomenon could be created by other complaining customers. Findings obtained through this thesis are as follows: If cognitive disharmony is created by customers who purchased products through the internet shopping malls, this can lead to private complaining behaviors, and subsequently, these behaviors are formed through e-Community. If the internet shopping mall companies do not take any timely and proper measures to intervene in the stage of private complaining behaviors in the first place, these behaviors will immediately escalate into the public complaining behaviors. Furthermore, the complaints will be transferred to other potential customers, ultimately resulting in their swift expansion. In other words, contrary to intention of the internet shopping mall companies, e-CRM does not facilitate the potential customers purchase decision, it rather affects them to postpone or withdraw their purchase decision. Accordingly, the internet shopping mall companies are required to manage e-Community with extreme care, and they should promptly respond to the complaining customers so that e-Community can function properly.

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Characteristics of Tide-induced Flow and its Effect on Pollutant Patterns Near the Ocean Outfall of Wastewater Treatment Plants in Jeju Island in Late Spring (제주도 하수처리장 해양방류구 인근해역의 늦은 봄철 조류 특성과 조석잔차류에 의한 오염물질의 분포 특성)

  • KIM, JUN-TECK;HONG, JI-SEOK;MOON, JAE-HONG;KIM, SANG-HYUN;KIM, TAE-HOON;KIM, SOO-KANG
    • The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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    • v.26 no.2
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    • pp.63-81
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    • 2021
  • In this study, we investigated the tide-induced flow patterns near the ocean outfall of the Jeju and Bomok Wastewater Treatment Plants (WTP) in Jeju Island by using measurements of Acoustic Doppler Current Meter (ADCP) and a numerical experiment with inserting passive tracer into a regional ocean model. In late spring of 2018, the ADCP measurements showed that tidal currents dominate the flow patterns as compared to the non-tidal components in the outfall regions. According to harmonic analysis, the dominant type of tides is mixed of diurnal and semi-diurnal but predominantly semidiurnal, showing stronger oscillations in the Jeju WTP than those in the Bomok WTP. The tidal currents oscillate parallel to the isobath in both regions, but the rotating direction is different each other: an anti-clockwise direction in the Jeju WTP and a clockwise in the Bomok WTP. Of particular interest is the finding that the residual current mainly flows toward the coastline across the isobath, especially at the outfall of the Bomok WTP. Our model successfully captures the features of tidal currents observed near the outfall in both regions and indicates possibly high persistent pollutant accumulation along the coasts of Bomok.

Effects of Soil Conditioner "Uresol and Bitumen" Treatments on Water Movement and Soil Loss II. The Changes of Wetting Angle and Water Diffusivity (토양개량제(土壤改良劑) Uresol 및 Bitumen처리(處理)가 토양(土壤)의 수분이동(水分移動)과 유실(流失)에 미치는 영향(影響) II. 습윤각(濕潤角)과 수분(水分)의 광산계수변화(鑛散係數變化))

  • Jo, In-Sang;Cho, Seong-Jin
    • Korean Journal of Soil Science and Fertilizer
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    • v.17 no.1
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    • pp.12-17
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    • 1984
  • In order to find out the effects of soil conditioner treatment on the water movement in sandy loam and silt loam soils were treated with two different kinds of soil conditioners, hydrophobic Bitumen 0.4% or hydrophillic Uresol 0.6%, and the changes of wetting angle (soil-water contact angle), penetrability and diffusivity were measured. The results were summarized as follows: 1. Uresol 0.6% treatment decreased the wetting angle of sandy loam more than $10^{\circ}$, but there was no big difference in silt loam. 2. Sandy loam soil was changed to almost hydrophobic and the wetting angle of silt loam soil was increased to $84.9^{\circ}$ as compared to $76.0^{\circ}$ of untreated soil by Bitumen 0.4% treatment. 3. By Uresol treatment, penetrability of sandy loam was doubled but there was not difference in silt loam, and it was decreased to half in two soils by Bitumen treatment. 4. A significant positive correlation between penetrability and the cosine of wetting angle was recognized. 5. Soil water diffusivity was greatly changed by soil conditioner treatment, and the big differences were appeared at lower soil moisture content.

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A Study on Tensile Restraint Crack Critical Stress Characteristcs of Gravity-Wet-Type Underwater Welded Joints (중력식 습식 수중용접부의 인강구속균열 임계응력 특성에 관한 연구)

  • O, Se-Gyu;Gang, Mun-Ho;Han, Sang-Deok
    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • v.23 no.2
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    • pp.61-65
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    • 1987
  • In this study, the characteristics of TRC (tensile restraint crack) critical stress in the gravity type underwater wet welding process and in the in-air welding have been investigated for Y, y and 45$^{\circ}$r grooves using the KR Grade A-3 steel plates and the E4303 covered electrodes. The following results were obtained: (1) In the TRC tests, the initial critical stress of Y groove is higher than those of the 45$^{\circ}$r single bebel grooves in both in-air and underwater weldings, and the cold fracture sensitivity is higher in the underwater welding than in the in-air welding. (2) The hardness of underwater weld metal is the highest in heat affected zone is about Hk 365 in the in-air weld but Hk 670 in the underwater weld which is higher for cooling speed is more rapid, resulting in the lower critical stress by increase of fracture sensitivity. (3) The diffusible hydrogen quantity for 48 hours is about 18cc/100g-weld-metal in the in-air welding but 48cc/100g-weld-metal in the underwater welding. So that, in the case of underwater welding the diffusible hydrogen penetrates about 3 times more than that in the in-air welding.

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A Study on Tensile Restraint Crack Critical Stress Characteristcs of Gravity-Wet-Type Underwater Welded Joints (중력식 습식 수중용접부의 인강구속균열 임계응력 특성에 관한 연구)

  • Sae Kyoo Oh;Moon Ho Kang;Sang Deok Han
    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • v.23 no.2
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    • pp.15-15
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    • 1987
  • In this study, the characteristics of TRC (tensile restraint crack) critical stress in the gravity type underwater wet welding process and in the in-air welding have been investigated for Y, y and 45°r grooves using the KR Grade A-3 steel plates and the E4303 covered electrodes. The following results were obtained: (1) In the TRC tests, the initial critical stress of Y groove is higher than those of the 45°r single bebel grooves in both in-air and underwater weldings, and the cold fracture sensitivity is higher in the underwater welding than in the in-air welding. (2) The hardness of underwater weld metal is the highest in heat affected zone is about Hk 365 in the in-air weld but Hk 670 in the underwater weld which is higher for cooling speed is more rapid, resulting in the lower critical stress by increase of fracture sensitivity. (3) The diffusible hydrogen quantity for 48 hours is about 18cc/100g-weld-metal in the in-air welding but 48cc/100g-weld-metal in the underwater welding. So that, in the case of underwater welding the diffusible hydrogen penetrates about 3 times more than that in the in-air welding.

Antibacterial Activities of Et-OH Extract from Extruded White Ginseng on Tooth Decay Bacteria (압출성형 백삼 Et-OH 추출물의 충치유발균에 대한 항균활성)

  • Son, Hyun-Jung;Han, Min-Soo;Ryu, Gi-Hyung
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.38 no.7
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    • pp.951-957
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    • 2009
  • In this study, antibacterial activity of extruded ginseng extract by 60 and 80% Et-OH were investigated by agar diffusion assay against two bacteria causing dental caries (Streptococcus mutans and Lactobacillus casei). Extrusion conditions were 20% moisture content $100^{\circ}C$ and $140^{\circ}C$ barrel temperature. The inhibition effect of 60% Et-OH ginseng extract was higher than 80% Et-OH ginseng extract. The minimum inhibitory concentration (MIC) of 80% Et-OH extruded ginseng extract at 140 and $100^{\circ}C$ barrel temperature against L.casei were 100 and 150 mg/mL respectively using broth assay method. The amount of glucosyltransferase (GTase) inhibitory content was the highest in extruded ginseng at $140^{\circ}C$ barrel temperature with 60% Et-OH. Moreover, n-hexane and n-butanol fraction ginseng extract had potential against tested bacteria. Our results demonstrated that antibacterial activities of extruded ginseng extract at $140^{\circ}C$ barrel temperature were more effective than Ex-$100^{\circ}C$, RG and WG.

Thermal Properties of Rocks in the Republic of Korea (한국의 암석 열물성)

  • Park, Jeong-Min;Kim, Hyoung-Chan;Lee, Young-Min;Shim, Byoung-Ohan;Song, Moo-Young
    • Economic and Environmental Geology
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    • v.42 no.6
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    • pp.591-598
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    • 2009
  • We made 2511 thermal property measurements on igneous, metamorphic, and sedimentary rock samples from Korea. The average thermal conductivities of igneous, metamorphic, and sedimentary rocks are 3.10 W/m-K, 3.76 W/m-K, and 3.54 W/m-K, respectively. Igneous rock can be classified into pluton, hypabyssal rock, and volconic rock; the average thermal conductivities of those rock types are 3.16 W/m-K, 3.26 W/m-K, and 2.77 W/m-K, respectively. Nonclastic sedimentary rock has higher thermal conductivity than clastic sedimentary rock. Thermal conductivity of Palezoic era rock is higher than Mesozoic era rock, because dominant mineral contents play an important role in the determination of thermal conductivity. Thermal conductivity of rocks is influenced by porosity. Therefore thermal conductivity of sedimentary rocks generally decreases with increasing porosity. Thermal conductivity and thermal diffusivity show linear correlation, its correlation coefficient of igneous, metamorphic, and sedimentary rocks are 0.775, 0.855, and 0.876, respectively.

Purification of the Yolk Protein, and Identification of the Synthetic Site of Its Precursor in Eriocheir japonicus (Decapoda, Brachiura) (동남참게(Eriocheir japonicus)의 난황단백질 정제와 그 전구체의 합성부위 구명)

  • HAN Chang-Hee;BAE Hyun-Hwan
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.25 no.5
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    • pp.432-442
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    • 1992
  • To identify the histological site of synthesis of yolk protein precursor, vitellogenin, by immunocytochemical method in the freshwater crab Eriocheir japonicus, we purified the yolk protein, vitellin, from crude egg extracts, and prepared the anti-rabbit serum against vitellin. Then, the site of vitellogenin synthesis was demonstrated by immunotytochemical method with PAP(peroxidase-antiperoxidase) reaction using the rabbit antiserum aganist vitellin. Female specific serum protein was identified in female serum by immunoelectrophoresis and Ouchterlony's immunodiffusion test for mature male and female sera. Based on the immunoelectrophoresis and Ouchterlony's diffusion test for mature male and female sera and crude egg extracts using antiserum against vitellogenic female serum absorbed with male serum, the female specific serum protein was identified as vitellogenin, detected in female serum only. The major yolk protein, vitellin, was purified from the crude egg extracts by DEAE-cellulose ion exchange chromatography, followed by sepharose CL-4B gel filteration chromatography. The molecular weight of vitellin was estimated to be about 245,000 dalton by sepharose CL-4B gel filteration chromatography. from the results of immunological analysis for vitellin, it was found that the vitellin antiserum contained the antibody against vitellogenin. In the results of immunocytochemical reaction by PAP method with the rabbit antiserum against vitellin, the vitellogenic oocytes and the hepatopancreas of mature female showed positive PAP reaction, but not in follicle cells and previtellogenic oocytes nf ovary, muscle of female and mature male hepatopancreas. Therefore, it showed that the hepatopancreas of mature female is the site of vitellogenic synthesis.

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Spread of Publication of the Literary Collection by Wood-block printing in the Late of Joseon Dynasty - Centered on wooden blocks for printing housed in KSAC - (조선후기 영남 문집 목판본 간행의 확산 양상에 관한 연구 - 한국국학진흥원 소장 책판을 중심으로 -)

  • Son, Ke-Young
    • Journal of Korean Library and Information Science Society
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    • v.44 no.3
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    • pp.447-470
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    • 2013
  • The purpose of this study is to examine how the cultural aspects of the publication of literary collections have been changed from its time throughout the entire Joseon Dynasty. At the royal court in the early Joseon Dynasty, the need for publication of the literary collections has consistently arisen to preserve writings of the noted sages, and the Joseon government was also taking the lead and promoting the publication of the literary collections. From the 16th to the early 18th century, the publication was intensively made at the local governments led by local governors. From the 17th to the early to middle of the 18th century, the finances of local governments were limited with the changed taxation system, and there had been a dramatic decrease in the number of literary publication projects. On the other hand, with the sudden increase of the number of Seowons during the reign of King Sukjong, the focus of the literary publication was moved to Seowon from the 18th to the 19th century. After the enforcement of the Seowon Abolition Decree, the collections were still published at Seowons, however from the end of 19th century, the publication of literary collections had been explosively made by aristocrats who did not belong to the institution of Seowon or could not receive Seowon's support, which spreaded over the entire Yangban culture.