• Title/Summary/Keyword: 반응 안정성

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Surgical Treatment of Lipoid Pneumonia - A case report - (지질성 폐렴의 외과적 치료)

  • 이계선;정진악;금동윤;안정태;이재원;나문주;백만순
    • Journal of Chest Surgery
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    • v.32 no.2
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    • pp.194-197
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    • 1999
  • We experienced an extremely rare case of lipoid pneumonia combined with empyema. A 53-year-old patient was admitted because of chilling sensation and blood tinged sputum. Simple X-ray and computered tomography(CT) showed a huge homogeneous opacification in the left lower lung field. This patient was diagnosed as endogenous type lipoid pneumonia by a computed tomography guided needle biopsy; decortication and left lower lobectomy are performed. We diagnosed it as endogenous type lipoid pneumonia because it revealed a foreign body reaction and lipid laden macrophage on the pathologic examination.

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Retail-Store Type Digital Signage Solution Development And Usability Test Using Android Mini PC (안드로이드 미니PC를 이용한 Retail-Store형 디지털사이니지 솔루션 개발 및 사용성 테스트)

  • Lim, Jungtaek;Shin, Dong-Hee
    • The Journal of the Korea Contents Association
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    • v.15 no.4
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    • pp.29-44
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    • 2015
  • Digital Signage, a way of advertising or delivering information to viewers through digital displays, has expanded from being just an advertising channel in public places. Recently, it has become widely prevalent in restaurants and retail stores. Despite its wide expansion, digital signage is limited to specific usages and services and the devices it uses are also quite expensive. This study introduces a stick-type digital signage product that operates on Android OS, which addresses all the weaknesses of digital signage with much more reasonable pricing and stable operation. For stability, performance tests were executed on the hardware and applications. The results for hardware performance were extremely promising, as each scenario's maximum performance results, measured by Load Runner programs, reached target indexes. Also, as a result of the usability test, all participants, including non-digital signage system users (novices), were able to easily learn all the tasks. As a result of user satisfaction survey, positive responses were exhibited for ease of learning and usability (LEU), helpfulness and problem solving capabilities (HPSC), affective aspect and multimedia properties (AAMP), commands and minimal memory load (CMML), and control and efficiency (CE).

Efficient Cyclization of Substituted Diphenols : Application to the Synthesis of Sulforhodamine B (치환 다이페놀의 효율적 고리화 반응: 설퍼로다민B의 합성에의 응용)

  • Park, Min Kyun;Shim, Jae Jin;Ra, Choon Sup
    • Clean Technology
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    • v.21 no.2
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    • pp.102-107
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    • 2015
  • Rhodamine dyes are widely used as fluorescent probes because of their excellent photophysical properties, such as high extinction coefficients, excellent quantum yields, great photostability, relatively long emission wavelengths. A great synthetic effort has been focused on developing efficient and practical procedures to prepare rhodamine derivatives, because for most applications the probe must be covalently linked to another (bio)molecule or surface. Sulforhodamine B is one of the most used rhodamine dyes for this purpose, because it carries two sulfoxy functions which can be easily utilized for binding with other molecules. Recently, we needed an expedient, practical synthesis of sulforhodamine derivatives. We found the existing procedure for obtaining those compounds unsatisfactory, particularly, with the cyclization process of the dihydroxytriarylmethane (1) to produce the corresponding xanthene derivative (2). We report here our findings, which represent modification of the existing literature procedure and provide access to the corresponding xanthene derivative (2) in a high yield. Use of methanol as a co-solvent was found quite effective to prohibit the water molecule produced during the cyclization reaction from retro-cyclizing back to the starting dihydroxytriarylmethane and the yield of the cyclization was increased (up to 84% from less than 20%). The reaction temperature was significantly lowered (80 vs. 135 ℃). Thus, the reaction proceeds in a higher yield and energy-saving manner where the use of reactants and the production of chemical wastes is minimized.

Design Parameters of Sequencing Batch Reactor treating ship sewage (연속 회분식 공정(SBR)을 이용한 선박 오 ${\cdot}$ 폐수처리 설계인자 도출)

  • Park, Sang-Ho;Kim, In-Soo
    • Proceedings of the Korean Institute of Navigation and Port Research Conference
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    • v.29 no.1
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    • pp.293-298
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    • 2005
  • Lab scale experimental study was carried out for SBR process, to investigate the effects of influent ship sewage organic compound removal and Bacillus sp. state on design parameters. This process was able to remove nitrogen and phosphorus as well as organic matter efficiently. More than 95% of chemical oxygen demand(COD) were removed. In addition, about 97% of total nitrogen (T-N) was reduced. The total phosphorus(T-P) reduction averaged 93%. The performance load of SBR process was shown to be 0.095kg ${\cdot}$ TOC/$m^{3}$ ${\cdot}$ day. The pH was decreased from 8.1 to 7.0 within 30 min and increased to 7.3 at the end of anoxic stage, and these phenomena were explained. The sluge produced in the SBR process is characterized by low generation rate (about 0.36kg ${\cdot}$ MLSS/kg ${\cdot}$ TOC) and excellent settleability. The number of Bacillus sp. in the SBR was 24.2%, indicating that Bacillus sp. was a predominant species in the reactor.

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Formation of Hydrogen Peroxide by the Ozonation of Aqueous Humic Acid (수중 부식산의 오존처리시 생성되는 과산화수소의 농도 변화에 대한 연구)

  • Kim, Kei Woul;Rhee, Dong Seok
    • Analytical Science and Technology
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    • v.13 no.5
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    • pp.659-665
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    • 2000
  • The changes in $UV_{254}$ and concentrations of $H_2O_2$ formed by ozonation of aqueous humic acid in ozone/high pH, peroxone process and in the presence of radical scavenger, $HCO_3{^-}$ were investigated. This study confirmed that the formation of $H_2O_2$ by ozonation may undergo different reaction pathways compared to those of $UV_{254}$ reduction in the degradation of the humic acid. The concentration of $H_2O_2$ produced by ozonation was found to be increased with decreasing pH of the sample solution due to the higher stability of ozone molecules at acidic conditions. On the while, $UV_{254}$ reduction was found to be higher at alkaline conditions or larger amount of $H_2O_2$ additions as a radical promoter in which the producing of ${\cdot}OH$, ${\cdot}HO_2$ radicals can be more favorable. From the results, it has been suggested that the formation of $H_2O_2$ by ozonation depends mainly on the direct reactions of ozone with humic acid molecules, while $UV_{254}$ reduction is affected by both the indirect reactions of the radicals and direct reactions of ozone with humic acid.

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Advanced Wastewater Treatment using Sequencing Batch Reactor on ship's sewage (연속 회분식 공정(SBR)을 이용한 선박 오·폐수의 고도처리)

  • Park Sang-Ho;Kim In-Soo
    • Journal of Navigation and Port Research
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    • v.29 no.5 s.101
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    • pp.475-480
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    • 2005
  • Lab scale experimental study was carried out for SBR process, to investigate the effects of influent ship sewage organic compound removal and Bacillus sp. state on design parameters. This process was able to remove nitrogen and phosphorus as well as organic matter efficiently. More than $92.0\%$ of chemical oxygen demand(COD) were removed. In addition, about $84.0\%$ of total nitrogen (T-N) was reduced. The total phosphorus(T-P) reduction averaged $93\%$. The performance load of SBR process was shown to be $0.095kg{\cdot}TOC/m3{\cdot}day$. The pH was decreased from 8.1 to 7.0 within 30 min and increased to 7.3 at the end of anoxic stage, and these phenomena were explained. The sludge produced in the SBR process is characterized by low generation rate (about $0.36kg{\cdot}MLSS/kg{\cdot}TOC$) and excellent settleability. The number of Bacillus sp. in the SBR was $24.2\%$, indicating that Bacillus sp. was a predominant species in the reactor.

Methionyl-tRNA-synthetase is a Novel Interacting Protein of LRRK2 (파킨스병 유전인자인 LRRK2와 상호작용하는 methionyl-tRNA synthetase)

  • Kim, Hyejung;Ho, Dong Hwan;Son, Ilhong;Seol, Wongi
    • Journal of Life Science
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    • v.28 no.2
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    • pp.170-175
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    • 2018
  • Parkinson's disease (PD) is the most common movement disorder and the second most common neurodegenerative disease after Alzheimer's disease. Approximately 5~10% of PD patients are familial PD cases. Leucine-rich repeat kinase 2 (LRRK2) has been known to be a causal gene of PD when it is mutated. LRRK2 contains the functional kinase and GTPase domains as well as leucine-rich repeat (LRR) and WD40 domains that are known to play critical roles for protein-protein interaction, suggesting that LRRK2-interacting proteins are important regulators for PD pathogenesis. In an effort to identify proteins interacting with LRRK2, we carried out co-immunoprecipitation of LRRK2 antibody using extracts of NIH3T3 cells that express LRRK2 at a relatively high level. The mass spectrometry analysis of a precipitated band revealed that the co-precipitated band was methionyl-tRNA synthetase (MRS), an ancient enzyme that transfers methionin to its cognate tRNA. The interaction of MRS with LRRK2 was confirmed again by co-immunoprecipitation of endogenous proteins and GST pull-down assays. However, LRRK2 did not phosphorylate recombinant MRS protein in in vitro kinase assays, and over-expression of LRRK2 or MRS did not affect the stability of its partner protein. Our data indicate that LRRK2 interacts with but does not phosphorylate MRS, and the stability of each partner is not affected by the other.

Evaluation of the Cytotoxicity and Mechanical Strength of Dental Duplex Stainless Steel Orthodontic Wire (치과 교정용 듀플렉스 스테인리스 스틸 와이어의 기계적 강도 및 세포독성 평가)

  • Lee, Myung-Kon;Kim, Chi-Young
    • The Journal of the Korea Contents Association
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    • v.10 no.9
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    • pp.309-317
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    • 2010
  • The stainless steel wire is extensively used for the orthodontic treatment. But, the stainless steel wire that has commonly superior corrosion resistance has caused hypersensitive reaction or allergy as side effects because of corrosion in the oral environment. For improving the problem of corrosion, we was evaluated the suitability of the duplex stainless steel(DSS) as orthodontic wire through this study. The DSS wire was evaluated the mechanical strength and bio-stability for suitability and bio-compatibility as orthodontic wire. In this work, the DSS and stainless steel(SS) as common use of medical grade were prepared for the tensile strength test. The DSS wire were treated by heat. and Temperature conditions of the heat treatment were $28^{\circ}C$, $500^{\circ}C$, $600^{\circ}C$, $700^{\circ}C$, $800^{\circ}C$, $900^{\circ}C$, respectively. And the DSS wires that treated by heat on the optimum temperature condition were conducted the bending moment test and calculated the S-Max value and the modulus of elasticity. For evaluating the bio stability, each materials were conducted in vitro test for measuring the cell survival rate. The most interesting results was that the tensile strength test of SS wire($8.17\times10^4\;N/mm^2$) and DSS wire($8.05\times10^4\;N/mm^2$) that treated at $500^{\circ}C$ by heat were similar in mechanical strength. In the bio-stability study, the DSS has no cytotoxicity (p=0.05) Thus, we could make a conclusion that the duplex stainless steel wire has vastly superior corrosion resistance was suitable as orthodontic wire.

The Effects of Insoluble Polymers on Water Stability of Carbon Fiber Reinforced Polymer-MDF Cementitious Composites (불용성 폴리머가 탄소섬유 보강 Polymer-MDF 시멘트 복합재료의 기계적 특성에 미치는 영향)

  • 김태진;박춘근
    • Composites Research
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    • v.12 no.3
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    • pp.84-90
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    • 1999
  • High alumina cement(HAC) and polyvinyl alcohol(PVA) based macro-defect-free(MDF) cement composites were reinforced using short carbon fibers, 3mm in length, 1-4% in weight fraction and insoluble polymers such as polyurethane, epoxy, phenol resin, in order to increase mechanical properties and water stability. The specimens were manufactured by the low heat-press(warmpress) method. In addition, the interface and the cross-linking reaction of cement and polymers was also studied by the SEM and TEM. Flexural strength of HAC/PVA based MDF cementitious composites was proportionally decreased with increasing fiber contents due to the undensified structure around fibers. The flexural strength of insoluble polymer added specimen was decreased with increasing fiber contents, while water stability was dramatically improved. Epoxy resin added specimen showed the highest strength with increasing fiber contents, compared with other specimens. The water stability of fiber content 4% added specimen immersed in water presented about 95%, 87% at 3 and 7 days immersed in water, respectively. The interfacial adhesive strength of fiber-matrix was very much improved due to cross linking reaction of polymer and metal ions of cement. Tensile strength of insoluble polymers added composites as linearly increased with increasing the fiber contents. The epoxy resin added specimen also showed highest tensile strength. The 4% fiber added specimen presented 30~80% higher strength than controlled specimen.

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A Trend in Research and Development of Natural Gardenia Pigments (천연 치자 색소의 연구개발 동향)

  • Shin, Hyun-Jae
    • KSBB Journal
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    • v.22 no.5
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    • pp.271-277
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    • 2007
  • Natural pigments have many applications like colouring agent, pigments, food additives, and antiseptics. At present, instead of synthetic pigments that have contributed to the development of industry, many kinds of natural pigments have been developed. The constituents of gardenia fruits, Gardenia jasminoides ELLIS, are traditionally known as herb medicine and natural dyes/pigments due to the customer is needs. The fruits produce yellow carotenoid pigments and iridoid compounds. The two main components in the yellow pigments are called crocin and crocetin. The extraction mode of yellow pigment from Gardenia is depended upon the extraction time, temperature, and volume of solvent. Red pigments or blue pigments formed from geniposide and amino acids have been reported a lot. Geniposide, the principal iridoid glucoside contained in gardenia fruit, was hydrolyzed to genipinic acid or genipin as a precursor for the pigment by enzymatic or chemical reaction. These red or blue pigments prepared with materials hydrolyzed of geniposide and amino acid and had properties governed by the electrostatic character of the amino acid. The pigments showed good stability to heat and pH but were gradually bleached by light while the other natural pigments are unstable in light, heat, acid, and base solution. The safety of the pigments was considered to be of little virulences in comparison to synthetic pigments.