• Journal of the Korean Chemical Society
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• v.25 no.6
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• pp.376-382
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• 1981

The rates and the activation parameters for the reaction of phenacyl bromide with substituted anilines in methanol and dimethylformamide were measured. The effects of substituted anilines were discussed. The rate of the reaction was increased with the electron donating power of substituent and showed larger value in DMF than in MeOH. The isokinetic relationship was shown between ${\delta}H^{\neq}$ and ${\delta}S^{\neq}$, isokinetic temperature was 539 and $400^{\circ}C$ in MeOH and DMF respectively, but p-nitro aniline was deviated from linearity in both solvents caused by solvent effects. The excellent linear relationship between log k and p$K_a$ of substituted anilines was observed by following equation. log k = 0.57p$K_a$-1.28 (r = 0.996) in MeOH at $45^{\circ}C$, log k = 0.65p$K_a$-0.88 (r = 0.970) in DMF at $45^{\circ}C$. From the Hammett plot, this reaction was a nucleophilic displacement of aniline to phenacyl bromide and the following equation was obtained at $45^{\circ}C$. log k/$k_0$ = -2.00${\sigma}$ + 0.06 (r = 0.985) in MeOH; log k/$k_0$ = -2.22${\sigma}$ + 0.08 (r = 0.995) in DMF. Large deviation of p-nitro aniline in DMF is resulted from solvent effects too. From above results, the substituent effect of this reaction can be described as $S_N2$ mechanism and bond formation more proceeds in DMF relative to MeOH.

• Journal of the Korean Chemical Society
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• v.52 no.5
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• pp.476-481
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• 2008

• Science of Emotion and Sensibility
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• v.2 no.1
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• pp.61-68
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• 1999

본 연구의 목적은 운전 상황과 도로 상황에 따른 자율신경계의 반응을 측정하는 것이다. 지금까지의 생리 신호는 대부분 제한된 실험실에서 측정되었고, 이 결과들은 자연스러운 상황에 측정된 데이터와는 차이가 있을 것이다. 그러므로 보다 동적인 환경에서 인간의 감성을 추출하고자 본 연구를 수행하였다. 건강한 5명의 피험자로부터 심박 변화율, 피부 저항, 피부온도 등의 생리 신호를 측정하였다. 먼저, 정차, 정속 주행, 급출발, 급제동의 운전 상황 변화에 따른 자율신경계의 반응을 측정하였고, 둘째로, 직선 도로와 굴곡이 심한 도로에서 정속 주행을 하면서 생리 신호를 측정하여 도로상황 변화에 따른 자율신경계의 반응을 측정하였다. 정차 및 정속 주행에 비해 급출발, 급제동일 때, 직선도로에 비해 굴곡이 심한 도로에서 주행을 할 때 평균 R-R 간격은 감소하였고, 전력 스펙트럼의 (LF+MF)/HF비는 증가하였고, 피부온도는 감소하였고, 피부저항은 증가하였다. 본 연구로부터, 정차 및 정속 주행에 비해 급출발, 급제동일 때 그리고 직선도로에 비해 굴곡이 심한 도로에서 주행을 할 때 교감신경계의 활성화비가 증가한다는 일치된 경향을 관찰할 수 있었다. 앞으로 피실험자수를 늘려 보다 정확한 통계적 분석을 하고자 한다.

• Proceedings of the Korea Information Processing Society Conference
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• 2013.11a
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• pp.241-244
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• 2013

본 논문에서는 가정의 전력 사용에 따라 실시간으로 전력요금을 알림으로써 사용자의 선택에 따라 자발적인 전력관리를 수행하는 수요반응 연동 홈 전력관리 시스템을 제안한다. 제안시스템은 수요반응 연동을 통한 사용자의 전력소비 패턴을 이용해 자발적인 전력관리를 하여 저 전력으로 유지되며 응답시간을 줄였다. 또한 에너지 소모와 사용자의 전력 관리 요청의 반응 속도에 대한 실험을 통해 우수성을 입증하였다.

• Journal of the Korean Chemical Society
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• v.23 no.4
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• pp.243-247
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• 1979

Kinetics of the reaction of phenethyltosylate with substituted pyridines at 50, 60 and 70$^{\circ}C$ in acetonitrile were investigated by an electric conductivity method. The effects of substituents on the reaction of phenethyltosylate with pyridines were discussed. The rates of reaction were increased with electron donating power of substituents of pyridines. The isokinetic relationship was shown $E_{\alpha}$ and ${\Delta}S^{\neq}$, it's temperature was 240$^{\circ}$K. Bronsted plots were excellent linear except for 4-amino pyridine given by the following equation, logk=O. 22pKa-3.71 (r=O. 986). According to a plot of log k against Hammett substituent constants, the Iinearity was good except for bamino pyridine too, log k= -1.330${\sigma}$+0.08 (r= -0.987). In both cases, deviation of 4-amino pyridine from linearity was considered to solvent effect, resonance effect and ${\sigma}$ value itself. From all the above results, this reaction was found typical $S_N2$ reaction which the rates of reaction was determined by C…N bond formation at transition state.

• Korean Journal of Clinical Laboratory Science
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• v.56 no.2
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• pp.171-180
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• 2024

The endotoxin test is based on the reaction between Limulus Amebocyte Lysate (LAL) and the lipopolysaccharides of Gram-negative bacteria. In this study, we sought to identify factors that interfere with the LAL testing of radiopharmaceuticals and evaluated acceptable ranges. A gel-clot LAL test and a chromogenic LAL test were used as endotoxin tests. We compared the performances of the Endosafe^Ⓡ LAL and recombinant Endosafe^Ⓡ Recombinant Cascade Reagent (rCR) cartridges for the chromogenic test. The factors that interfered with ⁶⁸Ga-DOTATOC injection were pH, 4-(2-hydroxyethyl) piperazine-1-ethanesulfonic acid (HEPES) buffer, and organic solvents, especially ethanol. However, interference by these factors was overcome by diluting the ⁶⁸Ga-DOTATOC injection tenfold. In addition, no interference was observed at pH values between 4 and 8, at a HEPES concentration of 2,000 ㎍/mL, or an ethanol concentration of <1%. Furthermore, results showed that interfering factors had similar effects on the performances of the Endosafe^Ⓡ LAL and Endosafe^Ⓡ rCR cartridges. The results of this study are expected to be useful for evaluating factors that interfere with the endotoxin testing of new radiopharmaceuticals.

• Korean Journal of Food Science and Technology
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• v.25 no.1
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• pp.69-77
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• 1993

Substrate removal efficiency of industrial wastewater from dye plant was investigated with fluidized-bed biofilm reactor(FBBR). Wastewater was diluted by 2, 3 and 6 times for experiment. When F/M ratio was increased 0.2 to 0.3, substrate removal efficiency of wastewater was rapidly decreased in all dilution ratio. Substrate removal efficiency was increased with dilution ratio in same F/M ratio, with hydraulic retention time. In case of 6 times diluted wastewater, below 0.2 F/M ratio, removal efficiency of BOD was $90{\sim}97%$. For reactor design, the parameters such as Y, $k_d$ and r was obtained as follows: $Y=0.3365\;k_d=0.03782\;day^{-1}\;r=0.997$ in 2 times diluted $Y=0.3341\;k_d=0.02750\;day^{-1}\;r=0.996$ in 3 times diluted $Y=0.3365\;k_d=0.03434\;day^{-1}\;r=0.998$ in 6 times diluted

• Korean Journal of Microbiology
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• v.50 no.4
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• pp.275-280
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• 2014

Leucine-responsive Regulatory Protein (Lrp) from Escherichia coli is an 18.8 kDa protein composed of 164 amino acids. Wild type Lrp (Lrp Wt) does not possess any tryptophan amino acid which has strong intrinsic fluorescence, whereas the mutant Lrp R145W contains a single tryptophan at the position 145 in the leucine-responsive domain. To investigate the fluorescence character, the Lrp R145W and Lrp Wt proteins were purified. The fluorescence intensity of Lrp R145W is much higher than that of wild type protein, and the intensity of Lrp R145W was decreased by binding to its specific DNA designed from ilvIH operon and to L-leucine. In addition, the tryptophan fluorescence intensity of Lrp R145W was strongly quenched by addition of acrylamide even in the least amount of concentration as well as by urea. The data obtained from this study may give valuable information on the three dimensional structure of Lrp R145W.

• Journal of Energy Engineering
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• v.6 no.1
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• pp.26-33
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• 1997

Highly crystalline Cu-ZSM5 was prepared without using organic templates. Several ion exchange treatments between Na$\^$＋/ and Cu$\^$2＋/ brought about excess loading of copper ions on the ZSM5 zeolite and the resultant zeolite was active for the decomposition of NO. This indicates that the copper ions excessively loaded on the ZSM5 zeolite are effective for the NO decomposition. When oxygen was added to a reactants, the conversion of NO decreased. NO, O$_2$TPD experiments explained that the active sites for NO decomposition and the adsorption sites of O$_2$, were the same. O$_2$, at the surface of ZSM5 zeolite was desorbed incompletely after pretreatment at 500$^{\circ}C$, and CU-ZSM5 pretreated with H$_2$at 500$^{\circ}C$ showed promoted activity at the start of reaction. Thus, it seems clear that O$_2$, adsorbed ai the surface of catalyst inhibits the catalytic activity.

• Korean Journal of Microbiology
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• v.43 no.3
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• pp.179-185
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• 2007

In this study, we used the method of guanidin isothiocyanate and boiling with Chelex-100 resin to extract genomic DNA of Ralstonia solanacearum from soil. It is more efficient than general protocols to remove inhibitory compounds in soil and R. solanacearum on. Then, we applied polymerase chain reaction and DNA enzyme-linked immunosorbent assay (ELISA) to identify and detect pathogen. The fliC gene of R. solanacearum was selected for specific detection of pathogen and primer sets were designed. Among the primer sets, two specific and sensitive primer sets, RsolfliC(forward: 5-GAACGCCAACGGTGCGAACT-3 and reverse; 5-GGCGGCCTTCAGGGAGGTC-3, designed by J. $Sch\ddot{o}nfeld$ et al.) and RS_247 (forward: 5-GGCGGTCTGTCGGCRG-3 and reverse; 5-CGGTCGCGTTGGCAAC-3 designed by this study), were designed to perform nested PCR. Nested PCR primer was labeled with biotin for hybridization between nested PCR product and probe to analyze with DNA ELISA.