• Journal of the Korean Society of Radiology
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• v.18 no.3
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• pp.239-248
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• 2024

Radiation therapy uses high energy, which can have side effects on the human body. Therefore, it is important to ensure that the appropriate dose is set for irradiation and to have confidence in the radiation produced by the generator. The EPR/Alanine dosimetry system is characterized by water equivalence, dose response linearity, and low fading, which makes it useful for quality control of radiation therapy equipment. In this study, we compared the signal and dose response curves of EPR/Alanine dosimetry by mass of alanine using 6 MV energy of a LINAC. An alanine dosimeter and EPR spectrometer from Burker, and a LINAC from Elekta, were used. A dose response curve and a 1st order regression equation were constructed from the irradiated dose and the EPR signal from the alanine dosimeter. We compared the signal magnitude and dose response curve with mass and checked the confidence through the measurement uncertainty of the dose response curve. As a result, it was found that the magnitude of the EPR signal increased by about 1.3 times at 64.5 mg, and the sensitivity of the dose response curve increased as the mass increased. The measurement uncertainty was evaluated to be between 5.84 % and 8.93 %. Through this study, it is expected that the EPR/alanine dosimetry system can be applied to the quality assurance and quality control of a LINAC.

• Proceedings of the Korean Society for Rock Mechanics Conference
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• 2000.09a
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• pp.155-161
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• 2000

It is very important to control the final load that acts on a support system, in tunnel engineering. A reliable analysis is needed to carry out technically reasonable design and safe construction. Also, a series of procedures of construction and the rock-support interaction behavior must be considered. Most existing studies have been performed as the limited analysis based on the simplified assumption. In this study, through the analysis of a circular tunnel using a 2-D finite differential code, the rook-support interaction behaviors in the variation of rock and stress conditions are analyzed and compared with the results from the closed form solutions. Consequently, more realistic rock-support interaction curves are obtained by including the effects of initial stresses and rock condition. These cures are very useful to predict the required support pressure in the initial design stage.

• Tunnel and Underground Space
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• v.10 no.3
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• pp.403-409
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• 2000

It is very important to control the final load that acts on a support system, in tunnel engineering. A reliable analysis is needed to carry out technically reasonable design and safe construction. Also, a series of procedures of construction and the rock-support interaction behavior must be considered. Most existing studies have been performed as the limited analysis based on the simplified assumption. In this study, through the analysis of a circular tunnel using a 2-D finite differential code, the rock-support interaction behaviors in the variation of rock and stress conditions are analyzed and compared with the results from the closed form solutions. Consequently, more realistic rock-support interaction curves are obtained by including the effects of initial stresses and rock condition. These curves are very useful to predict the required support pressure in the initial design stage.

• Journal of Soil and Groundwater Environment
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• v.11 no.1
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• pp.14-22
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• 2006

Laboratory column experiment for simultaneous removal of Cd and Cr(VI) were conducted using newly developed material of Fe-loaded zeolite having both reduction ability and sorption capacity. The solution containing Cd and Cr(VI) was injected into the column and the breakthrough curves (BTCs) for the contaminants were observed at the effluent port. Cd breakthrough was not initialized until Cr(VI) breakthrough was completed. Therefore it could be concluded that overall efficiency of Fe-loaded zeolite should be determined by the reactivity for Cr(VI). The relative concentration of Cr(VI) BTC increased to the unit value while initial breakthrough was delayed and the propagation of breakthrough was slowed. In order to quantitatively describe the shape of Cr(VI) BTC, new parameters of ${\alpha}\;and\;{\beta}$ designated to be shape parameters, were defined and applied in contaminant transport concentration. These parameters were employed to represent the degree of initial breakthrough delay and the degree of breakthrough propagation, respectively. As initial contaminant concentration increased, ${\alpha}$ decreased, which indicated the delay of BTC's initiation. And as initial contaminant flow rate increased, ${\beta}$ decreased, which represented the faster propagation of the BTC. From these results, Fe-loaded zeolite was found to be an effective reactive material for PRBs against heavy metals having different ionic forms in groundwater. And it could be expected that as groundwater flows faster, the propagation of breakthrough would be faster and as contaminant concentration is higher, the initial point of breakthrough would appear earlier.

• Proceedings of the Korea Water Resources Association Conference
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• 2011.05a
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• pp.430-430
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• 2011

최근 지구온난화, 엘리뇨 및 라니냐 등 지구환경 변화에 따른 기후변화의 영향으로 짧은 시간에 매우 높은 강도를 가진 이상호우에 의해 많은 인명과 재산피해가 발생하고 있다. 우리나라의 경우에도 1990년대 후반부터 과거와 달리 국지적 집중호우가 빈번히 발생하고 있으며 집중호우에 의한 홍수는 우리나라의 가장 빈번한 자연재해 중 하나가 되었다. 이러한 성격의 홍수는 소유역 규모의 좁은 지역과 급경사지역에서 짧은 지속시간과 집중적인 강우강도에 의해 발생하고, 빠른 유속과 토사를 동반하는 빠른 수문반응으로 홍수에 대비할 시간이 부족한 것이 특징이기 때문에 기존의 홍수예보모형을 이용하여 발생홍수의 특성을 예측하기에는 많은 어려움이 있다. 유출수문곡선의 특성을 분석하여 홍수의 특성을 분석하는 연구는 Kyiamah (1996)가 유출수문곡선의 기초적인 상승곡선, 지체시간, 첨두홍수량을 이용하여 돌발홍수사상에 대한 크기를 산정하였으며, 이를 바탕으로 Bhaskar 등 (2000)은 유출수문곡선의 상승부 기울기, 첨두 홍수량비, 홍수 반응시간을 이용하여 돌발홍수지수(Flash Flood Index)를 산정하고 이 지수에 의해 돌발홍수를 설명하고자 하였다. 국내에서는 정재철 (2000)이 보청천을 대상으로 단 몇 개의 사상만을 대상으로 Bhaskar 등 (2000)이 제시한 돌발홍수지수를 적용한 바가 있다. 그러나, 이들 연구에서는 소수의 수문사상만을 이용하였기 때문에 상대심도를 산정하는데 있어 문제가 있으며 상대심도를 산정하는데 있어 각 심도계수들의 임의적인 도수분포를 이용하였기 때문에 매우 주관적이라고 할 수 있다. 김병식 등 (2008)은 한강유역의 과거 101개의 홍수사상에 대해 돌발홍수의 상대심도를 파악하기 위하여 돌발홍수지수를 산정하고 2006년 7월의 집중호우에 의해 발행한 홍수사상의 돌발홍수 심도를 시간 및 공간적으로 정량화하였다. 이러한 기존의 연구는 홍수심도 산정시에 필요한 유출수문곡선을 실측된 자료를 이용하여 산정하였으나 국내의 소유역의 경우 실측된 유출수문곡선 자료가 그다지 많지 않은 관계로 인해 홍수심도를 산정하는데 많은 어려움을 내포하고 있다. 따라서 본 연구에서는 미계측 소유역중 시범유역을 선정하고 30년 이상 장기간 실측 강우의 기왕최대 시강우량 자료에 대하여 강우-유출모형을 통한 홍수유출수문곡선을 모의한 후, 빈도별 확률강우량에 대한 수문곡선 특성인자들의 비를 무차원 지수화하여 극한홍수사상에 대한 설계강우의 취약성을 평가하기 위한 홍수위험지수 (Flood Hazard Index) 산정방법을 제시하였다.

• Proceedings of the Korean Statistical Society Conference
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• 2003.05a
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• pp.7-12
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• 2003

문항반응이론(IRT)에서 문항특성곡선(ICC)의 모수를 추정하는 경우에 발생되는 초기값(initial value) 문제를 비선형 로지스틱모형을 선형 회귀모형으로 근사화하여 해결하고자 하였다. 특히, 신규 또는 잡음이 섞인(local fluctuation) 문항의 직접적인 평가와 소규모집단별 검사가 이루어질 수 있는 현실적 문제에서 모수추정의 대안으로서 그 의의가 있을 수 있다.

• Proceedings of the Korean Society for Rock Mechanics Conference
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• 1995.03a
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• pp.41-47
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• 1995

NATM공법에서 지보는 주로 암반반응곡선(Ground Reaction Curve, GRC)상에서 설계된다. 그러나 GRC는 유도과정에서 많은 가정을 지니고 있어 시공에 직접 반영하기에는 많은 한계를 지닌다. 특히 과지압에 의한 소성거동의 문제가 심각하지 않고, 암반의 거동이 불연속면에 영향을 많이 받는 지역에서는 GRC의 가정 중에 하나인 등방 연속체라는 가정은 큰 결점 중의 하나이다. (중략)

• Journal of Korean Tunnelling and Underground Space Association
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• v.4 no.3
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• pp.175-184
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• 2002

Ground reaction curve is very useful information for estimating the installation time of the tunnel support. The ground reaction curve can be estimated by analytical closed form solutions derived in case of circular section and isotropic stress condition. The nature of the ground reaction, however, depends significantly on tunnel configurations. Nevertheless, few purely analytical and experimental studies of this problem due to tunnel configurations appear to have been carried out. Therefore, it is necessary to investigate the influence of tunnel configurations in order to use simply in practical design. This paper describes a numerical study for the intial elastic displacement in the ground reaction curve due to configuration of tunnel excavation. In order to evaluate the applicability of analytical closed form solution in practical design, the parametric studies were carried out by numerical analysis in elastic tunnel behaviour. In the studies, S value, namely configuration factor, defined as the ratio between tunnel height (b) and width (a), varies between 0.5 and 3.0, initial ground vertical stress varies between 5~30 MPa for each S values. The results indicated that the self-supportability of ground is larger in the ground having low S value. It, however, is suggested that the applicability of closed form solution may not be adequate to determine directly the installation time of the support and self-supportability of ground. It should be necessary to perform the additional numerical analysis.

• Journal of the Korea institute for structural maintenance and inspection
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• v.7 no.1
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• pp.181-190
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• 2003

The convergence-confinement method is an attempt to evaluate tunnel stability conditions by means of a mathematical model and a ground response curve. In this study, the convergence-confinement method by numerical model was examined. This method don't need the basic assumptions for a mathematical model. Also This is applicable to general tunnel. According to the results of this study, the change of shotcrete stiffness and the load-distribution ratio used for 2-Dimension numerical analysis are not signficant factors. The ground response curve and the support reaction curve are mutually dependent. Especially the support reaction curve depends upon the ground response curve. The mechanism of tunnel must be analyzed by the interaction between support and ground. Consequently the stability of tunnel must be qualitatively investigated by a ground response curve and quantitatively adjudged by a numerical analysis for the reasonable design of tunnel.

• Proceedings of the Korean Society of Applied Pharmacology
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• 1996.04a
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• pp.176-176
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• 1996

축산식품중에 잔류하고 있는 sulfamethazine을 검출하기 위하여 sulfamethazine에 대한 단클론항체를 생산하고 이를 이용하여 효소면역측정법을 개발하였다. 면역원은 sulfamethazine에 KLH를 그리고 흡착항원은 BSA를 glutaraldehyde법으로 결합시켰다. 면역원으로 Balb/c mouse를 면역시킨 다음 비장 형질세포률 얻어 myeloma cell과 융합하여 융합잡종세포를 만들었다. Sulfamethazine에 대한 항체를 분비하는 융합잡종세포를 단계회석법과 ELISA를 이용하여 cloning하여 D2, A9, B8, Bl 클론을 얻었다. 이들 클론에서 얻어진 단클론항체를 사용하여 indirect competitive ELISA를 실시하여 표준곡선을 작성하여 본 결과 농도의존성 곡선을 얻을 수 있었다. 4클론중에서 A9 클론을 사용하여 다른 유사한 sulfonamide듣과 p-aminobenzoic acid와 교차반응을 조사한 결과 sulfamerazine에 12.5%의 교차반응을 보였으나 다른 설파제에 대해서는 교차 반응을 보이지 않았다.