• Herbal Formula Science
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• v.32 no.3
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• pp.223-233
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• 2024

Objectives : Natural products containing bioactive compounds with high antioxidant activity are potentially important sources that can contribute to the improvement of various diseases. Therefore, the aim of this study was to investigate phenolic compounds of Cinnamomum cassia (C. cassia) ethanolic extract (CCEE). And then we evaluated the antioxidant effect. Methods : We used liquid chromatography with tandem mass spectrometry (LC-MS/MS) to identify the compounds in CCEE. LC-MS/MS was performed in positive ion mode using Shimadzu, Nexera HPLC system and IDA TOF mass system. Solvent A was distilled water and solvent B was acetonitrile as mobile phase. The analysis was performed at a flow rate of 0.5 ml/min, column temperature of 35 ℃ and wavelength of 284 nm. The antioxidant effect of CCEE was analyzed using DPPH (2,2-diphenyl-2-picrylhydrazyl free radical) and ABTS (2,2'-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid)). In addition, total phenolics and total flavonoids contents were measured to determine antioxidant effects. Results : Analysis using LC-MS/MS identified four compounds: Coumarin, Trans-cinnamaldehyde, Trans-cinnamic acid, and 2-Methoxycinnamaldehyde. Free radicals decreased in a concentration-dependent manner starting from 10 ㎍/ml of CCEE, and decreased to a level similar to Ascorbic acid (AA) from a concentration of 60 ㎍/ml onwards. Conclusions : Based on the findings, CCEE exhibits strong antioxidant activity as evidenced by the presence of Coumarin, Trans-cinnamaldehyde, Trans-cinnamic acid, and 2-Methoxycinnamaldehyde. Consequently, this study suggests that CCEE can serve as an important source of natural antioxidants and can be efficiently used in the management of oxidative stress diseases.

• Herbal Formula Science
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• v.32 no.3
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• pp.263-275
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• 2024

Background : Recent studies have shown that stress fundamentally influences the functional modulation of organ and stress-related disease causes high morbidity and mortality rates. Objective : The present research investigated the effect of restraint stress on psychological and physiological responses. Results : Body weight and food intake were changed in stress group. Body weight has continuously decreased, and food intake has been slightly altered. As a result of measuring each tissue's weight, the liver and kidney's weight loss was greater than that of other organs. The lipid profile of stressed animals showed significant increases in cholesterol (TC), triglyceride (TG), low-density lipoprotein (LDL), and high-density lipoprotein (HDL) levels compared to control. As hepatic marker enzymes, serum glutamic pyruvic transaminase (GPT; alanine aminotransferase), glutamic oxalacetic transaminase (GOT; aspartate aminotransferase), and lactic dehydrogenase (LDH) were increased in the stress group. However, levels of serum cortisol and corticosterone did not affect. Results of the behavioral tests show that the stress group has increased activity, sluggish movements, and anxiety in the central part compared with the control group through the open field test. In the forced swim test, the stress group models had a longer duration of slowing movement, and its rate also increased. Also, in immunoblotting, stress increased the inflammatory factors Inducible Nitric Oxide Synthase (iNOS), cyclooxygenase-2 (COX-2) and activated the mitogen-activated protein kinase (MAPK) pathway. Conclusions : We observed that mouse model were affected behavioral response and liver injury when exposed to restraint stress, indicating the importance of the restraint stress in the development of psychological and physiological processes.

• Korean Journal of Remote Sensing
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• v.37 no.6_1
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• pp.1611-1623
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• 2021

Thisstudy demonstratessoil moisture and evapotranspiration performance using Korea Land Data Assimilation System (KLDAS) under Korea Land Information System (KLIS). Spin-up was repeated 8 times in 2018. In addition, low-resolution and high-resolution meteorological data were generated using meteorological data observed by Korea Meteorological Administration (KMA), Rural Development Administration (RDA), Korea Rural Community Corporation (KRC), Korea Hydro & Nuclear Power Co.,Ltd. (KHNP), Korea Water Resources Corporation (K-water), and Ministry of Environment (ME), and applied to KLDAS. And, to confirm the degree of accuracy improvement of Korea Low spatial resolution (hereafter, K-Low; 0.125°) and Korea High spatial resolution (hereafter, K-High; 0.01°), soil moisture and evapotranspiration to which Modern-Era Retrospective analysis for Research and Applications, version 2 (MERRA-2) and ASOS-Spatial (ASOS-S) used in the previous study were applied were evaluated together. As a result, optimization of the initial boundary condition requires 2 time (58 point), 3 time (6 point), and 6 time (3 point) spin-up for soil moisture. In the case of evapotranspiration, 1 time (58 point) and 2 time (58 point) spin-ups are required. In the case of soil moisture to which MERRA-2, ASOS-S, K-Low, and K-High were applied, the mean of R² were 0.615, 0.601, 0.594, and 0.664, respectively, and in the case of evapotranspiration, the mean of R² were 0.531, 0.495, 0.656, and 0.677, respectively, indicating the accuracy of K-High was rated as the highest. The accuracy of KLDAS can be improved by securing a large number of ground observation data through the results of this study and generating high-resolution grid-type meteorological data. However, if the meteorological condition at each point is not sufficiently taken into account when converting the point data into a grid, the accuracy is rather lowered. For a further study, it is expected that higher quality data can be produced by generating and applying grid-type meteorological data using the parameter setting of IDW or other interpolation techniques.

• Journal of the Korean Association of Geographic Information Studies
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• v.23 no.4
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• pp.83-100
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• 2020

This study evaluated the accuracy of soil moisture and evapotranspiration by calculating the hydrological parameters in Korean peninsula using Land Information System(LIS) developed by US NASA. We used Noah-MP surface model to calculate hydrological parameters, and used MERRA2(Modern-Era Retrospective analysis for Research and Applications, Version 2) for hydrological forcing data. And, International Geosphere-Biosphere Program(IGBP) and University of Maryland(UMD) land cover maps were applied to compare the output accuracy, and Automated Synoptic Observing System(ASOS) of KMA was used as ground observation data. In order to evaluate the accuracy of the output data, the correlation coefficient(CC), BIAS, and efficiency factor (NSE, Nash-Sutcliffe Efficiency) were analyzed with soil moisture and evapotranspiration by ASOS ground observation data. As a result, the correlation coefficient of soil moisture using IGBP was 0.56 on average, and evapotranspiration was about 0.71. On the other hand, soil moisture using UMD was 0.68 on average and evapotranspiration was about 0.72, and the correlation coefficient by UMD was evaluated as high accuracy compared to the results by using IGBP. The correlation coefficient of soil moisture was an average of 0.68 and evapotranspiration was an average of 0.72 when MERRA2 was used as hydrological forcing data. On the other hand, the soil moisture applied with ASOS was an average of 0.66, and evapotranspiration was an average of 0.72. It is judged that the ASOS point data was reanalyzed as 0.65°× 0.5°grids, which is the same spatial resolution with MERRA2, resulting in differences in accuracy depending on the region.

• Journal of the Korean Association of Geographic Information Studies
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• v.24 no.4
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• pp.65-81
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• 2021

In this study, soil moisture and evapotranspiration were calculated throughout South Korea using the Korea Land Data Assimilation System(KLDAS) of the Korea-Land Surface Information System(K-LIS) built on the basis of the Land Information System (LIS). The hydrometeorological data sets used to drive K-LIS and build KLDAS are MERRA-2(Modern-Era Retrospective analysis for Research and Applications, version 2) GDAS(Global Data Assimilation System) and ASOS(Automated Synoptic Observing System) data. Since ASOS is a point-based observation, it was converted into grid data with a spatial resolution of 0.125° for the application of KLDAS(ASOS-S, ASOS-Spatial). After comparing the hydrometeorological data sets applied to KLDAS against the ground-based observation, the mean of R² ASOS-S, MERRA-2, and GDAS were analyzed as temperature(0.994, 0.967, 0.975), pressure(0.995, 0.940, 0.942), humidity (0.993, 0.895, 0.915), and rainfall(0.897, 0.682, 0.695), respectively. For the hydrologic output comparisons, the mean of R² was ASOS-S(0.493), MERRA-2(0.56) and GDAS (0.488) in soil moisture, and the mean of R² was analyzed as ASOS-S(0.473), MERRA-2(0.43) and GDAS(0.615) in evapotranspiration. MERRA-2 and GDAS are quality-controlled data sets using multiple satellite and ground observation data, whereas ASOS-S is grid data using observation data from 103 points. Therefore, it is concluded that the accuracy is lowered due to the error from the distance difference between the observation data. If the more ASOS observation are secured and applied in the future, the less error due to the gridding will be expected with the increased accuracy.

• Journal of KIISE:Information Networking
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• v.28 no.3
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• pp.389-405
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• 2001

In these days, we have increasing demands on the real-time services, especially for the multimedia data transmission in both of wired and wireless environments and thus efficient and stable ways of transmitting realtime data are needs. Although RTP is widely used for internet-based realtime applications, it cannot avoid packet losses, due to the use of UDP stack and its underlying layers. In the case of mobile computing applications, the packet losses are more frequent and consecutive because of the limited bandwidth. In this paper, we first statistically analyze the characteristics of packet losses in the wired and wireless communications, based on Gilbert model, and a new packet recovery scheme for realtime data transmission is presented. To reflect the transmission characteristics of the present network environment, our scheme makes the sender to dynamically adjust the amount of redundant information, using the current packet loss characteristic parameters reported by the receiver. Additionally, we use relatively large and discontinuous offset values, which enables us to recover from both of the random and consecutive packet losses. Due to these characteristics, our scheme is suitable for the mobile computing environment where packet loss rates are relatively high and varies rapidly in a wide range. Since our scheme is based on the analytic model form statistics, it can also be used for other network environments. We have implemented the scheme with Mobile IP and RTP/RTCP protocols to experimentally verify its efficiency.

• Herbal Formula Science
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• v.25 no.4
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• pp.483-497
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• 2017

Background : Behavioral stress has been suggested as one of the significant factors that is able to disrupt physiological systems and cause depression as well as changes in various body systems. The stressful events can alter cognition, learning, memory and emotional responses, resulting in mental disorders such as depression and anxiety. Results : We used a restraint stress model to evaluate the alteration of behavior and stress-related blood parameter. The animals were randomly divided into two groups of five animals each group. Furthermore, we assessed the change of body weight to evaluate the locomotor activity as well as status of emotional and anxiety in mice. After 7 days of restraint stress, the body weight had significantly decreased in the restraint stress group compared with the control group. We also observed stress-associated behavioral alterations, as there was a significant decrease in open field and forced swim test, whereas the immobilization time was significantly increased in the stress group compared to the control group. We observed the morphological changes of neuronal death and microglia by immunohistochemistry and western blot. In our study restraint stress did not cause change in neuronal cell density in the frontal cortex and CA1 hippocampus region, but there was a trend for an increased COX-2 and iNOS protein expression and microglia (CD11b) in brain, which is restraint stress. Conclusion : Our study, there were significant alterations observed in the behavioral studies. We found that mice undergoing restraint stress changed behavior, confirming the increased expression of inflammatory factors in the brain.

• Journal of the Korea Organic Resources Recycling Association
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• v.21 no.1
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• pp.85-93
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• 2013

The amount of salted food waste and non-salted food waste from household consisted of 4 family members was surveyed. And the feeding rate and growth rate of Eisenia fetida population upon the different food wastes such as vegetables, grains, fruits and salted food waste were investigated. Total amount of food waste from a household was 3,200g/week. i.e. 0.114kg/day/capita and non-salted food waste was 53.9% of food waste. Salt contents of vegetables, grains, fruits were 0.60, 0.36 and 0.33%, respectively, if they were assumed to have 70% water content. Salt content of salted food waste was 0.78%. Upon the non-salted vegetables and fruits, feeding rate of earthworm was high but growth rate was low. Upon the non-salted grains, feeding rate of earthworm was low but growth rate was high. Upon the food with 70% water content, earthworm could not feed and grow when salt content of food was over 0.6%, and earthworm could feed normally but showed low growth rate when salt content of food was 0.3%. These results indicated that earthworm could stabilize the non-salted food wastes with ease but could hardly stabilize the salted food wastes.

• Journal of the Korea Organic Resources Recycling Association
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• v.14 no.3
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• pp.101-109
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• 2006

Earthworms(Eisenia fetida) were fed with paper mill sludge produced from P&G or Yuhan Kimberly paper manufacturing factory, or cow dung manure. Turnover rate of feed into earthworm biomass and excreting rate on each feed were investigated on dry weight base. Biomass of earthworm population was increased on paper mill sludge, but it was fallen to death on cow dung manure, which had high electrical conductivity and low redox potential. When P&G paper mill sludge was supplied to adult, elder juvenile or younger juvenile for 84 days, turnover rate of feed into earthworm biomass was 0.48, 0.40 and 0.76%, respectively, and on Yuhan Kimberly paper mill sludge 0.26, 0.45, 0.42%. When P&G paper mill sludge was supplied to adult, elder juvenile or younger juvenile, excreting rate was 49.02, 54.32 and 55.39%, respectively and on Yuhan Kimberly paper mill sludge 32.22, 41.86, 40.69%, and on cow dung manure, 73.73, 57.89. 76.38%.

• Journal of the Korea Organic Resources Recycling Association
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• v.12 no.4
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• pp.105-111
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• 2004

When the clitellate tiger worms(Eisenia fetida) were fed with paper mill sludge, sewage sludge of agricultural-urban area and sewage sludge of agricultural area, number of cocoons produced by individual clitellate earthworm for 104 days were 11.8, 8.6 and 3.5, respectively. However, clitellate earthworms that had been fed with sewage sludge of agricultural-urban area for 52 days or fed with sewage sludge of agricultural area for 95 days could not produce cocoons, whereas the earthworms that were fed with paper mill sludge kept producing cocoons through the investigating period. The hatchability of cocoons produced by the clitellate tiger worms(Eisenia fetida) fed with sewage sludge of agricultural-urban region, sewage sludge of agricultural region and paper mill sludge were 42.8%, 38.3% and 39.2%, respectively. And hatching periods of cocoons were 33.8~36.0 days, which were not affected by the kinds of sludges. However, the cocoons produced by clitellate earthworms which had been fed with sewage sludge for about 1.5 months could not hatch at all. Death rates of second generation hatched from cocoons produced by tiger worms(Eisenia fetida) which had been fed with the sewage sludge from agricultural-urban region and the sewage sludge from agricultural region reached to 100% and 90% at 60 days after hatching, respectively, whereas death rate of second generation fed with paper mill sludge reached to 16%.