• 대한치과보철학회지
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• 제59권3호
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• pp.314-318
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• 2021

미만성 경화성 골수염(diffuse sclerosing osteomyelitis, DSO) 환자에서 임플란트를 사용하여 손실된 치아의 회복에 대한 보고는 거의 없다. DSO 환자는 임플란트의 골유착에 불리한 골질을 지니고 있기 때문에 임플란트를 식립할 때, 외과적 외상, 감염 관리 및 연장된 치유 기간과 같은 추가적인 고려사항이 필수적이다. 본 증례는 DSO 환자에서 임플란트 골유착의 실패와 성공에 관한 보고이다.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제29권5호
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• pp.293-297
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• 2003

Florid cemento-osseous dysplasia (FCOD) is a benign, non-neoplastic lesion characterized by multiple sclerosing masses only within jawbones. It is frequently confused with chronic diffuse sclerosing osteomyelitis (CDSO) in previous literatures. In our study, two cases of FCOD were examined to know the characteristics of their calcifying tissues. The first case was non-infected, while the second case was severely infected, displaying the typical features of CDSO in clinico-radiologic findings. The infected FCOD case showed a lot of bacterial colonies in the main lesion with relatively rare inflammatory reaction. The globular cementum-like materials of FCOD showed woven bone pattern and was positive for Alcian blue stain, and also positive for the antibodies of ameloblastin, bone morphogenetic protein (BMP) -2 and -4. On the other hands, in the immunostains of matrix metalloproteinase (MMP) -3, -9, -10, and $TNF-{\alpha}$, macrophage infiltrated in the FCOD lesion was rarely observed. These data suggest that the cementum-like materials of FCOD contain various matrix proteins, and that the cementum-like materials are relevant to the overgrowth of the bacterial colonies by inhibition of the regional inflammatory reactions.