• Korean Journal of Bronchoesophagology
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• v.10 no.2
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• pp.35-42
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• 2004

Background and objective : Rabeprazole is a new generation proton pump inhibitor, which has a rapid onset after first dose, predictable efficacy in all patients regardless of CYP2C19 genotype status, and less nocturnal acid breakthrough. The aim of the study is to investigate clinical efficacy and safety of rabeprazole sodium (Pariet 10mg qd)when administered once daily to patients with laryngopharyngeal reflux(LPR) disease. Methods : Among the patients who had visited the Department of Otolaryngology, those with LPR symptoms, had undergone laryngoscopy. Symptoms and endoscopic laryngeal sings were recorded initially, at 1 month, 2 months, 3 months, and more than 3 months, All patients were evaluated for clinical efficacy on the basis of symptom scores, reflux finding score(RFS), and side effects. Results : In general, most symptom scores and RFS improved over the time. Efficacy of the Pariet on LPR-related symptoms were $63.2\%,\;77.5\%,\;78.7\%,\;and\;90.9\%$ before 4 weeks, 4 to 8 weeks, 8 to 12 weeks, and after 12 weeks respectively. Efficacy on the RFS were $61.8\%,\;78.4\%,\;82.9\%,\;and\;85.5\%$ before 4 weeks, 4 to 8 weeks, 8 to 12 weeks, and after 12 weeks respectively. Pariet was well tolerated and was associated with few drug-related side effects. Conclusion Because of its efficacy and safety, Pariet may prove to be an alternative to currently available proton pump inhibitors.

• The KIPS Transactions:PartC
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• v.16C no.6
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• pp.699-706
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• 2009

The convergence tendency accelerates the realization of the ubiquitous healthcare (u-Healthcare) between the technology including the power generaation and IT-BT-NT of the ubiquitous computing technology. By rapidly analyzing a large amount of collected from the sensor network with processing and delivering to the medical team an u-Healthcare can provide a patient for an inappropriate regardless of the time and place. As to the existing u-Healthcare, since the sensor node all transmitted collected data by using with the Zigbee protocol the processing burden of the base node was big and there was many communication frequency of the sensor node. In this paper, the u-Healthcare system in which it can efficiently apply to mobile apparatuses it provided the transfer rate in which it is superior to the bio-signal delivery where there are the life and direct relation which by using the Bluetooth instead of the Zigbee protocol and in which it is variously used in the ubiquitous environment was designed. Moreover, by applying the EEF(Embedded Event Filtering) technique in which data in which it includes in the event defined in advance selected and it transmits with the base node, the communication frequency and were reduced. We confirmed to be the system in which it is efficient through the simulation result than the existing Electrocardiogram Measurement system.

• Journal of Sasang Constitutional Medicine
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• v.18 no.2
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• pp.55-67
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• 2006

1. Objective & Method The purpose of this study was to objectify the diagnosis of Sasang constitution. 163 children's voices were analyzed with 74 factors using PSSC-2004. 2. Results (1) In male children group, Taeumin's APQ4 was significantly low compared with the others. (2) In male children group, Taeumin's octave 5 & octave 6 were significantly low compared with the others. It was significant distinction between Taeumin and Soeumin at the result of post hoc. (3) In male children group, Taeumin's Time Domain Total Sum / Time Domain Count & Frequency Domain Total Sum / count(0) were significantly low compared with the others. It was significant distinction between Taeumin and Soeumin at the result of post hoc. (4) In male children group, Taeumin's 0k-2k total sum & 2k-4k total sum were significantly low compared with the others. It was significant for distinction between Taeumin and Soeumin at the result of post hoc. (5) In male children group, Taeumin's 2k-4k deviation was significantly low compared with the others. It was significant distinction between Taeumin and Soeumin at the result of post hoc. (6) In male children group, Taeumin's D# Total Energy & F# Total Energy were significantly low compared with the others. It was significant distinction between Taeumin and Soeumin at the result of post hoc. (7) In male children group, Taeumin's D# deviation & F# deviation were significantly low compared with the others. It was significant distinction between Taeumin and Soeumin at the result of post hoc. (8) In female children group, Soyangin's center frequency (7) was significantly high compared with the others. It was significant distinction between Taeumin and Soyangin at the result of post hoc. 3. Coclusion With these results, we got some information for standardization of the clinical diagnosis guideline of Sasang constitutional type classification using PSSC-2004 in the Korean children

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.10 no.6
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• pp.161-167
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• 2010

Social individualized broadcasting increases rapidly in an environment that combines communication and broadcasting. Real-time individualized broadcasting is a service that is provided by multiple individuals to many and unspecified persons. In contrast, newly introduced individualized broadcasting service is a service that has not been experienced socially and culturally and therefore many problems are expected. The newly emerging real-time individualized broadcasting service may bring about various dysfunctions as well as desirable functions. Establishment of guideline and its implementation based in vulnerability analysis are necessary to prevent the expected dysfunctions and reinforce the desirable functions. Therefore, the purpose of this paper is to examine dysfunctions of the information-oriented society which threaten cyber-norms, cyber-morality, cyber-dangers, cyber-democracy, etc. at the level of social individualized broadcasting service and to propose appropriate guidelines. Through this paper, first, future changes of dysfunctions of the information-oriented society due to individualized broadcasting service can be forecast, and countermeasures and policy directions can be proposed. Second, Dysfunctions of ICT-based service that may emerge in individualized broadcasting service can be forecast and correct guideline can be prepared to reduce potential dangers and increase desirable functions of the service. This paper will analyze in various aspects the characteristics of a new media with the focus on individualized broadcasting service among the new ICT-integrated services, and forecast the appearance and aggravation of the dysfunctions and then draw the guideline.

• Information Systems Review
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• v.17 no.2
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• pp.49-75
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• 2015

In this study, we propose an ubiquitous computing technology (UCT) based construction management (CM) framework which is composed of processes, information systems, and organizations. For this, we first define 14 promising UCT based CM tasks from 140 candidate tasks using a matrix analysis technique. After defining the 14 tasks, we survey the construction management experts with questionnaire of the importance, improvement possibility, ease of implementation of the tasks. Based on the survey results, we select three high priority tasks: material management, operation management, inspection and measurement management. We conceptually design the framework, that is, processes, information systems, and organizations for the 3 tasks to be more innovative by applying the UCT to the CM tasks. Finally, we apply the proposed framework to some construction fields and estimate the effectiveness of the framework. Estimation results show that the CM tasks can be performed more quickly with less man powers using the UCT-based CM framework.

• Journal of Life Science
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• v.25 no.8
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• pp.880-888
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• 2015

Foeniculum vulgare (FV) has long been used in traditional medicine for the treatment of inflammatory diseases. In addition, it is usually known as an important medicinal and aromatic plant widely used as a carminative, digestive, lactogogue, and diuretic, and for treating respiratory and gastrointestinal disorders. The skin barrier protects against the invasion of pathogens, fends off chemical and physical assaults, and protects against extensive water loss. In this study, the effects of solvent-fractionated FV fruits on strengthening the skin barrier and maintaining moisture, as well as their antifungal activity, were investigated in human keratinocyte (HaCaT) cells. The expression of involucrin, loricrin, filaggrin, hyaluronic acid synthase, human β defensin, and cathelicidin genes and proteins was measured by reverse transcription polymerase chain reaction (RT-PCR) and western blotting. The production of hyaluronic acid was determined by enzyme-linked immunosorbent assay (ELISA). The butanol fraction increased the expression of involucrin and filaggrin. Both the ethyl acetate and the butanol fractions increased hyaluronic acid production by promoting the expression of hyaluronic acid synthase-1. Although the antimicrobial peptides were increased by FV crude extract and its fractions, the samples did not show a significant effect compared to the normal group. These results suggest that the butanol fraction of FV could be very useful in cosmetics for the treatment of dermatological diseases.

• Culinary science and hospitality research
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• v.21 no.6
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• pp.264-279
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• 2015

This study is conducted to investigate the relationships among service quality, satisfaction, and revisit intention of franchise snack bars customers located in Busan. The quality of franchise Korean snack bars' service was estimated by examining three sub-dimensions: service environment factors, interaction factors, and outcome quality factors, which are classified from Brady & Cronin's third-dimensional model. The survey was performed from March 9th to March 13th in 2015. Total 300 questionnaires were distributed and 272 questionnaires were employed for final analysis. SPSS 21.0 program was used to derive the following: factor analysis, reliability analysis, correlation, simple regression and multiple regression analysis. In results, the approachableness such as convenience for access was the most important reason when people choose a franchise Korean snack bar company followed by food taste and reasonable price. In addition, the results indicate that service environment quality, interaction quality, and outcome quality have all positive impact on the customers' satisfaction as well as revisit intention. Specifically, outcome quality have the greatest influence on the satisfaction and revisit intention among three service quality factors. This outcome proves that Korean snack bar franchise companies need to investigate more to improve their outcome quality such as food quality and serving time to satisfy customers. In conclusion, current study confirmed the relationships among service quality, satisfaction, and revisit intention in context of franchise snack bar stores. These results will suggest the snack bar foodservice segmentation as valuable marketing strategic, and that it can be utilized as a fundamental data to establish an efficient business plan in the industry.

• Journal of Korean Society of Occupational and Environmental Hygiene
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• v.11 no.2
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• pp.102-110
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• 2001

To establish an accurate asbestos analysis method for workplace samples, chrysotile, amosite, crocidolite, tremolite, actinolite, and anthophyllite asbestos fibers were analyzed for their morphology, atomic content and electron diffraction patterns. The morphology of asbestos fiber was evaluated in $10,000{\times}$ magnification. The atomic contents was analyzed by X-ray analyzer (TEM-EDX). Asbestos fibers were further assessed using electron diffraction (ED) patterns to provide an additional criterion for classifying the asbestos fibers. Twenty asbestos fibers were initially randomly selected for morphological evaluation; based on an aspect ratio (length : diameter = 3:1). Then the fibers were determined for their EDX spectrums and ED patterns. Our results showed that only chrysotile fiber has a hollow tube structure to be distinguished from other asbestos fibers. Although asbestos fibers had similar morphology, they had different EDX spectrums and ED patterns. Our results on the atomic content of asbestos fibers were very similar to those of other researchers, but amosite and crocidolite had a little difference in atomic content compared with the results from other researchers. The difference may be due to the difference in equipment or asbestos sample selection. A study on asbestos samples from biological specimens to establish a criterion for determining occupational asbestos exposed diseases should be done in the near future.

• Korean Journal of Veterinary Research
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• v.27 no.2
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• pp.321-330
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• 1987

In the endemic area of bovine piroplasmosis in Chonbuk Province, total of 486 heads of Holstein cow selected from 14 farms randomly were examined the infection status of piroplasma and their blood values. The results obtained were summarized as follows: 1. The etiological agent was only Theileria sergenti and none of the Babesia sp. infection. 2. All of the 486 heads of examined cow were infected with Theileria sergenti (100%). 3. In the initial examination of 11 farms in early summer, the means of blood values were as follows; RBC:$526{\pm}84(10^4/mm^3$), Ht:$27.9{\pm}2.8%$, SP:$7.5{\pm}0.6g/dl$, WBC: $11586{\pm}354/mm^3$, and Fibrinogen: $578.5{\pm}164.1mg/dl$. 4. In the second examinations in slimmer season, the blood values of examined cows had little varieties. But in the winter season, cows housed in the barn, the blood values were greatly increased; RBC: $601{\pm}77(10^4/mm^3)$, (F-value: 37.186**), Ht: $30.5{\pm}1.3%$(F-value: 15.626**) Hb: $12.2{\pm}1.3g/dl$(F-value: 5.899**), SP: $7.4{\pm}0.6g/dl$(F-value: 5.05**). 5. To determine the piroplasma infection in the many herds of cow, the measurement of Ht, Hb, and SP values etc. were more effective and helpful to find the weak cow because the examined process are not only to be easily carry out many samples but also to be done very simple and rapidly. 6. The indications of therapeutic standard values were stablished as follows; the less than 20% in the Ht value, below the 10g/dl in the Hb value, and less than 6g/dl in SP value. When the one among the therapeutic standard values, Ht, Hb, and SP was below the therapeutic standard value, the cow was treated with nutriments. When more than two among them were below the therapeutic standard, the cow was treated with Berenil, at once. In this way, there was no one head which represented clinical signs of piroplasmosis among 486 heads of cow at 14 farms during the year of 1986. 7. In a Korean native cattle infected with Thieleria sergenti seriously, the recovery of blood values was very prolonged by the treatment of Berenil only. But by the transfusion of 300ml blood collected from normal cow, the blood values were recovered rapidly.

• Korean Journal of Veterinary Research
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• v.37 no.2
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• pp.451-456
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• 1997

120 heads of korean native calves were examined of serum protein by using cellulose acetate electrophoresis. During 20 days since the calves were purchased, serum protein, fibrinogen values and plasma : fibrinogen ratio were examined in the calves with respiratory and diarrheal disease. The result obtained in this investigation were as follows : 1. Among the 120 heads of calves that were purchased from market, 14 heads(22%) of calves were occurred respiratory disease, and 12 heads(20%) of calves are occurred diarrhea. Occurrence of respiratory disease was 14.5(4~20) days in average and diarrhea was 9.6(2-15) days after they had been purchased. 2. Serum protein fraction were analyzed by cellulose acetate electrophoresis. ${\beta}-globulin$, A/G ratio and ${\beta}_2-globulin$ values were decreased in the calves with respiratory disease. Especially, ${\beta}_2-globulin$ were significantly decreased. In calves with diarrhea, there was no change in ${\beta}-globulin$ values. ${\beta}_2-globulin$ values were higher than that of the normal and respiratory diseased calves. 3. ${\alpha}-globulin$ values were increased in both of calves with diarrhea and respiratory disease. This tendency was due to increase ${\alpha}_2-globulin$ values. 4. The $\gamma$-globulin value of calves with diarrhea was the lowest among the 3 groups. 5. The total protein values of normal calves were $7.0{\pm}1.1g/dl$ and that of respiratory and diarrheal diseased calves were $6.9{\pm}0.9g/dl$ and $6.6{\pm}0.8g/dl$, respectively. Total protein value of calves with diarrhea was lower than that of normal and respiratory diseased calves. Globulin value of calves with diarrhea was the lowest among them. The low value of total protein in diarrheal diseased calves was due to decrease globulin values. 6. The fibrinogen values of calves with respiratory disease ($643{\pm}189mg/dl$) were significantly higher than that of normal calves($533{\pm}135mg/dl$) and calves with diarrhea($572{\pm}188mg/dl$). The plasma : fib. ratio of respiratory diseased calves was $12.0{\pm}4.9$, normal calves was $13.8{\pm}3.5$ and diarrheal diseased calves was $12.8{\pm}4.6$. The ratio of the calves with respiratory disease was significantly decreased.