• Journal of Chest Surgery
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• v.31 no.12
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• pp.1172-1182
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• 1998

Background: Primary goal of anticoagulation treatment in patients with mechanical heart valve is the effective prevention of thromboembolism and safe avoidance of bleeding as well. Material and Method: Two-hundred and nine patients with the St. Jude Medical prosthesis operated on between 1984 and 1995, for mitral(MVR 122), aortic(AVR 39) and double mitral and aortic valve replacement(DVR 48) respectively, were studied on the practically achieved levels of anticoagulation and the clinical outcomes. Patients were on Coumadin and followed up by monthly visit to outpatient clinic for examination and prothrombin time measurement to adjust the International Normalized Ratios(INRs) within the low-intensity target range between 1.5 and 2.5. Result: A total anticoagulation follow-up period was 1082.0 patient- years(mean 62.1 months) and INRs of 10,205 measurements were available for evaluation. The accomplished INRs among the replacement groups were not significantly different and only 65% of INRs were within the target range. And, in individual patients, only 37% of patients had INRs included within the target range in more than 70% of tests during follow-up period. The levels of INRs in patients with atrial fibrillation, which was found in 57% of patients, were definitely higher than the ones measured in patients with regular rhythm(p<0.001). Thromboembolisms were experienced by 15 patients with the incidence of 1.265%/patient- year(MVR 1.412%, AVR 0.462% and DVR 1.531%/patient-year) and major bleeding by 4 patients with the incidence of 0.337%/patient-year(MVR 0.424%, AVR none and DVR 0.383%/patient-year). Frequent as well as prolonged missing of prothrombin time tests was the main risk factor strongly associated with the thromboembolic complications(odds ratio 1.99). The proportion of INRs within target range of less than 60% in individual patient was the highly significant risk factor of both thromboembolic and overall embolic and bleeding complications(p<0.004 and p<0.002 respectively). Conclusion: In conclusion, the low-intensity therapeutic target range of INRs was adequate in patients with AVR and in sinus rhythm. However, the patients with replacement of the mitral valve were more likely to require higher target range of INRs, especially in the presence of atrial fibrillation, to achieve the practical levels of anticoagulation enough to prevent thromboembolic complications effectively. For the higher therapeutic target range of INRs between 2.0∼3.0, further accumulation of clinical evidences are required. It is highly desirable to improve the patients' compliance under continuous instructions in visiting outpatient clinic and in taking daily Coumadin without omission and to keep INRs consistently within optimal range with tight control for minimization of chances and of periods of exposure to the risk of complications. And, particularly, patients with high risk of complications and with wide fluctuation of INRs should be better managed with frequent monitoring anticoagulation levels.

• Journal of Korean Society of Transportation
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• v.18 no.6
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• pp.101-110
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• 2000

본 논문의 목적은 우리들의 현실적 노면표지 형태가 그 강도, 종류 및 출현빈도 측면에서 드러내는 지속적 증대 내지 강화 경향성을 문제점으로 제기하면서, 이런 노면표지 형태와 운전행동 간의 관련성에 대한 심리학적 제반 이론들을 고찰해보고 아울러 여기서 상호 연관적 특성을 밝혀주는 하나의 적절한 모델을 개발해보고자 하는 데에 두었다 이 모델에서는 운전자의 사고예방이나 안전운행이 곡 필요한 수준의 노면표지 자극화(stimulation)를 통해 조성된 쾌적한 교통환경에서 보다 용이하게 가능하다는 점이 전제되고 있다. 우리가 인간행동을 총체적으로나 효과적으로 분석하는 데 있어서는 일반심리적이거나 행동주의적 제반 이론 관점이 다소 미흡하다는 점이 지적되었다. 반면에 보다 거시적이고 종합적인 통찰에 중점을 두고있는 형태주의 심리학이나 장 이론적 시각은 행동분석 시에 비교적 결실적인 것으로 밝혀졌다 노면표지 자극의 양상여하가 운전자에게 스트레스, 정보과부담, 과도한 심리적 각성상태 등으로 인해 부정적인 영향을 미친다는 점에서는 이런 문제점이 환경심리학적 고찰측면에서도 관심의 대상이 되고 있다. \"노면표지 조성화 양 관점 모델\"에서 시사되고 는 터이지만. 이 모델에서의 노면표지 형태가 이론적인 면에서 \"정서-인지적\" 인간관에 근거를 두고있어 궁극적으로 이것이 옳다면, 그것은 곡 필요한 최소한의 수준에 머물러야 한다는 것이다. 올바른 운전행동, 다시 말해 교통법규 준수 행동은 노면표지 양상 측면의 각종 자극적 강화대책보다도 오히려 실효성 있는 교통교육, 확실한 적발 단속과 엄중한 처벌대책에 상대적으로 훨씬 더 큰 비중을 두고있는, 바로 그런 운전자의 의식개혁을 통해 비로소 제대로 정착될 수 있기 때문이다. 이 모델의 타당성 여부는 후속적 실증연구를 통해 해명되어질 수 있을 것이다.

• Journal of radiological science and technology
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• v.44 no.6
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• pp.599-605
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• 2021

The International Electrotechnical Commission (IEC) 62494-1 has defined the exposure index (EI) that have a proportional relationship with the dose incident on the image receptor, and target exposure index (EI_T), deviation index (DI). In this study, an appropriate EI_T for skull radiography was established through the diagnostic reference level (DRL) and changes in DI were confirmed. Entrance surface dose (ESD) and EI were obtained using the computed radiography system displayed the EI as per IEC on console and skull phantom by experiment based on the national average exposure conditions announced in 2012 and 2019. And appropriate EI_T was established by applying the DRL in 2012 and 2019. As a results, the EI_T is changed according to the change in the DRL, and the exposure condition that becomes the ideal DI according to the change in the EI_T also has a difference of about 1.41 times. DRL is recommended to optimize the patient dose, however it is difficult to measure in real time at medical institutions whereas EI and DI are displayed on the console at the same time as exposure. When the EI_T is set based on the DRL and the DI is closed to an ideal value, it is useful as a patient dose management tool. Therefore, when the EI_T is periodically managed along with the revision of the DRLs, the patient dose can be optimized through the EI, EI_T and DI.

• Fire Science and Engineering
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• v.20 no.3 s.63
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• pp.1-8
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• 2006

The purpose of this work is to analyze quantitatively if the safety instrumented system(SIS) like the pressure safety valves(PSV) in the processes of ethyl benzene plant have been designed relevantly to the safety integrity level because overpressure in the benzene or ethyl benzene columns causes the explosive reactions, fires and reactor explosions. The safety integrity level(SIL) 3 has been adopted as a target level of SIS based on the general data of the Probability of Failure on Demand of PSV, $1.00E-4{\sim}1.00E-3$. The standard model of the reliability has been set up and then the fault tree analysis of it has been carried out to get the PFD of SIS, and the results show 8.97E-04, 5.37E-04, 5.37E-04 for benzene prefractionator column, benzene column and EB column, respectively. Thus, we conclude that the SIS is designed to fulfill the condition of SIL3, and when the partial stroke test for the control valve are carried out every sixth month, the SIS of each column is expected to increase its reliability up to $22{\sim}27%$.

• Journal of the Society of Disaster Information
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• v.17 no.2
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• pp.289-305
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• 2021

Purpose: The purpose of this study is to check the importance of higher level, sub higher level and lower alternative factor and the factor for relieved life and also check the comprehensive priority in executed "Safety and relieved life level improvement of apartment house residents by AHP analysis". Method: The safety management evaluation elements and alternatives have been arranged as hierarchical structure based on the preceding studies and the advice of experts for the maintenance and system of apartment house in this study. Study model is used for the survey of pair wise comparison composition targeting experts and AHP analysis method is used for alternative plan ranking, etc. Result: The response result of survey secured the consistency and it is confirmed that safety inspection for apartment house electricity facility is most important for higher level, safety inspection, detailed inspection and diagnosis evaluation are most important for sub higher level and plumbing equipments is most important for alternatives based on the analysis result of relative weight comparison for sub higher level and alternatives for final goal attainment of the study. Conclusion: Plumbing equipments, crime prevention safety and electrical safety are shown as top priority alternatives when observe it with expert manager's point of view for apartment house. It shows that securing the importance of living safety accident and deciding the level of relieved life can be improved are the alternatives of pre-prevention and management strengthening.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.42 no.6
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• pp.763-773
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• 2022

Industrial and environmental facilities, which are national growth engine, must sustain their structural safety and maintain their process to continue production activities under various load conditions including natural hazards. In this study, by improving existing design codes which aim to secure the structural safety only, new structural and seismic design codes are proposed to secure both the structural safety and the operability of facilities. In the proposed structural design code, a variety of loads to reflect the characteristics of industrial and environmental facilities are considered and load combinations for the ultimate strength design and the allowable stress design of structures are suggested. Considering the importance of a unit industrial facility and that of a unit process, the seismic design class, design earthquake, and seismic performance level of a unit component are determined to achieve the dual seismic performance objectives for securing both the structural safety and the operability. Also, the proposed design code are applied to an example of an environmental facility in order to examine its applicability.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.7
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• pp.105-111
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• 2018

This study aims to evaluate the safety for cable stayed bridge due to damages on the cable system. Many cable supported bridges, including cable stayed bridge and suspension bridge, have been built in the Korean peninsula. This requires efficient maintenance and management since this structure has complex structural components and system. This large structure also often faces risks either from manmade or natural phenomenon. In 2015 one cable-stayed bridge in South Korea had been struck by a bolt of lightning on the cables. This event had led to fire on cables. These cables had been damaged and putting the bridge at risk. This bridge was back in used after a few weeks of investigations and replacements of the cables. However, enormous social and economic expense were paid for recovery. After this event risk based management for infra structures is required by public demands. Therefore, this study was initiated and aimed to evaluate risks on the cable system due to potential damages. In this paper one cable-stayed bridge in South Korea was selected and investigated its safety based on the damage scenarios of cable system for efficient and prompt management, and for supporting decision making. FEM analysis was conducted to evaluate the safety of the bridges due to damages on the cable system.

• 한국유가공학회:학술대회논문집
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• 2003.11a
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• pp.31-39
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• 2003

식품의 생리(약리)기능인 3기능의 강조는 인류에게 건강한 삶을 보장해 줄 것이라는 믿음을 주고 있고 인류 장수의 길을 한층 더 활기차게 끌고 갈 수 있는 원동력이 될 것으로 기대하고 있다. 세계시장의 움직임은 이러한 믿음이 이미 현실에서 나타나고 있음을 보여준다. 이미 식품 관련 분야의 대기업, 다국적 유통업체 및 제약업체도 적극적인 건강식품 시장참여 의사를 밝히고 있다. 이러한 국내외의 움직임을 반영하여 우리나라도 2002년 8월 26일 건강기능식품에 관한 법률을 공포하였다. 본 법률은 '건강기능 식품의 안전성 확보 및 품질향상과 건전한 유통, 판매질서를 확립하면서도 국민의 건강증진과 소비자보호에 이바지하기 위한' 것으로 2003년 8월 26일 부터 시행되었다. 건강기능식품은 국가의 의료비를 절감하고 국민의 건강 수준을 향상시키는 좋은 도구이다. 이와 같은 목표 달성을 위해서 해당 식품의 안전성과 유효성이 과학적으로 증명되어야 한다. 본 고에서는 건강기능식품 법률 시행을 맞이하여 국내의 관련 법령, 외국의 관리 체계 및 시장동향 등을 소개하고자 한다.

• Journal of the Korea Safety Management & Science
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• v.11 no.1
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• pp.205-211
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• 2009

In reality, distribution planning for a supply chain is established using a certain probabilistic distribution estimated by forecasting. However, in general, the demands used for an actual distribution planning are of deterministic value, a single value for each of periods. Because of this reason the final result of a planning has to be a single value for each period. Unfortunately, it is very difficult to estimate a single value due to the inherent uncertainty in the probabilistic distribution of customer demand. The issue addressed in this paper is the selection of single demand value among of the distributed demand estimations for a period to be used in the distribution planning. This paper proposes an efficient demand selection scheme for minimizing total inventory costs while satisfying target service level under the various experimental conditions.

• Proceedings of the Korea Information Processing Society Conference
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• 2012.04a
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• pp.672-675
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• 2012

SMART Highway 사업은 첨단 IT통신과 자동차 및 도로 기술이 접목된 세계 최고수준의 빠르고 편안한 지능형 녹색도로 실현을 목표로 하고 있다. SMART Highway의 도로-자동차 기반 교통운영에서 핵심기술인 VANET(Vehicular Ad-hoc Network)은 다수의 차량들이 무선통신을 이용하여 차량 간 통신 또는 차량과 RSU(Road Side Unit)사이의 통신을 제공하는 차세대 네트워킹 기술이다. 특히, 운전자의 안전에 직접적인 영향을 끼칠 수 있는 V2V 통신의 경우 차량 간의 안전한 통신을 위해 차량 간 상호인증이 반드시 고려되어야 한다. 이처럼 빠른 속도로 이동하는 차량 간 인증이 원활이 이루어지기 위해서는 기존의 네트워크에서 사용된 인증방식은 그대로 적용시키기 어렵다. 따라서 본 논문에서는 다수의 차량 간 통신 시에 보다 효율적인 차량 인증을 위해 카운팅 블룸필터를 이용한 차량 인증 기법을 제안한다.