• Title/Summary/Keyword: 면역글로블린

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Studies on the Separation of Immunoglobulin and Immunological Response from Korean Native Cattle (한우초유중 Ig의 분리 ${\cdot}$ 정제 및 면역 반응에 관한 연구)

  • Baick, Seung-Cheon;Kim, Yong-Hwi;Shin, Je-Ho;Yu, Je-Hyeon
    • Journal of Dairy Science and Biotechnology
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    • v.15 no.1
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    • pp.1-9
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    • 1997
  • This study was conducted to efficiently separate the Ig from Korean native cattle colostrum and to utilize them as an immunogen for the production of antibodies aginst rabbit. The results obtained were as follows : 1. About 84% of Ig G could be separated from Korean native cattle colostrum by·gel filtration using Superose 12 column on HPLC. The separation profile of Korean native cattle colostral immunoglobulin was similar that of Holstein colostral Ig. 2. Separation of Korean native cattle colostral Ig by anion exchange chromatography using Mono Q column on HPLC was poor resolution chromatographic pattern. 3. Hi-Trap Protein G column showed better results than the Protein A Sepharose CL-4B column in the Ig G binding capacity from Korean native cattle colostral Ig. 4. Protein G Sepharose Fast Flow system resulted in higher Ig g binding capacity as the industrial size scale-up approach. 5. Sufficient titer reaction of antibody to Korean native cattle colostral Ig G was confirmed by ELISA.

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The Effects of Line Dance on Immune function and Inflammation for Elderly Women (라인댄스가 여성노인의 면역기능 및 염증에 미치는 영향)

  • Beak, Soon-Gi;Chi, Dong-Cheol
    • Journal of Industrial Convergence
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    • v.19 no.6
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    • pp.187-195
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    • 2021
  • This study was conducted to identify the characteristics of immune function and inflammatory changes for elderly women, by having them to participate in line dance program. For this purpose, 18 elderly women in their 60s to 70s, living in Y city were selected, and 9 of the participants were randomly assigned to participate in the line dance program for 12-weeks (line dance exercise group), while the other 9 participants were assigned to carry out their daily lives without participating in certain physical activity (control group) for the same period. The subjects' immune function and inflammation were measured using SPSS 24.0 for datafication, and the average and two-way ANOVA analysis were conducted. The result indicates the immunoglobulin, IgA, has increased, but not dramatically. The level of IgG(p<.05), and IgM(p<.05) increase were detected from the line dance exercise group, but not so much from the control group. Inflammation indicator, the CRP(p<.05), were significantly reduced from the line dance exercise group, but not much for the control group. According to the collected data, line dance for the elderly women can be considered as an effective exercise program, and the result shows that inflammation is reduced and immune function is improved. It also implies the needs of active physical activity arbitration to keep the elderly women's health and to prevent the chronic disease in the future.

Infliximab treatment for a patient with refractory Kawasaki disease (Infliximab으로 치료한 난치성 가와사끼병 1례)

  • Yu, Hyo-Jung;Lee, Soo-Jin;Sohn, Sejung
    • Clinical and Experimental Pediatrics
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    • v.49 no.9
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    • pp.987-990
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    • 2006
  • Intravenous immunoglobulin (IVIG) infusion is an effective therapy for acute Kawasaki disease (KD). Nonetheless, approximately 10 percent to 20 percent of patients have persistent or recrudescent fever despite IVIG treatment, leading to a higher risk for coronary artery aneurysms (CAA). This unresponsiveness may pose a challenge to the clinicians. Tumor necrosis $factor-{\alpha}$ levels are elevated in the acute phase of the disease, especially in patients who develop CAA. We report a 10-month-old male with KD who failed to respond to multiple doses of IVIG and methylprednisolone and who then was treated with infliximab (5 mg/kg single dose). After infliximab treatment, he became afebrile with normalization of inflammatory markers and no further progression of CAA.

Effects of the Biological Function of Yogurt Added with Lycium chinence Miller Extract (구기자(Lycium chinence Miller)추출액을 첨가한 요구르트의 생리활성 효과)

  • Bae, H.C.;Cho, I.S.;Nam, M.S.
    • Journal of Animal Science and Technology
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    • v.47 no.6
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    • pp.1051-1058
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    • 2005
  • This experiment was carried out to investigate the biological function of Lycium chinence Miller yogurt. Antioxidant activity was higher in methanol extract yogurt than in water extract yogurt. The antioxidant activity was shown at 83.9% in Lycii folium extract yogurt, 47.0% in Lycii fructus extract yogurt and 54.0% in Lycii cortex extract yogurt. Angiotensin converting enzyme inhibitor activity was shown highly both in water extract and methanol extracts from the Lycii folium. The $\alpha$-glucosidase inhibitor activity was shown at the 4.0% concentration of Lycii folium extract yogurt, Lycii fructus extract yogurt and Lycii cortex extract. In an orally administrated rat, normal yogurt, Lycii fructus extract yogurt and Lycii cortex extract yogurt have no effect on blood cholesterol content. IgG production in blood is more increased in Lycii cortex extract yogurt than in normal yogurt and Lycii fructus extract yogurt.