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The Review of Environment, Food and Exercise on Allergy Anaphylaxis (환경, 음식 및 운동 알레르기 반응에 대한 고찰)

  • Kwak, Yi-Sub;Baek, Young-Ho;Kim, Seung-Hyun;Kim, Young-Il;Yoo, Byung-In
    • Journal of Life Science
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    • v.20 no.1
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    • pp.147-152
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    • 2010
  • Exercise-induced anaphylaxis (EIA) is a physical allergy, sometimes severe, triggered by exertion following specific food intake. It was defined for the first time in 1980. EIA is associated with different kinds of exercise. The clinical manifestations progress from itching, erythema and urticaria to some combination of cutaneous angioedema and vascular collapse. Mast cell participation in the pathogenesis of this syndrome has been proved by the findings of an elevated serum histamine level during exhaustive exercise. As predisposing factors of EIA, a specific or even nonspecific sensitivity to food has been reported. Food-dependent exercise-induced anaphylaxis (FDEIA) is a distinct form of food allergy induced by physical exercise. It is typified by the onset of anaphylaxis during exercise which was preceded by the ingestion of the causal food allergens. The diagnosis of FDEIA is heavily dependent on clinical history. Allergy tests may need to be performed using a broad panel of food and food additives. As with food allergies, FDEIA diagnosis is based on interview, biological test and skin test. Prophylaxis aims to prevent a recurrence; the patient should be given an emergency kit to deal with any recurrent episodes. After the food allergen has been identified, it should be avoided for at least 4 to 5 hours before any exercise. Two cases of EIA are presented (EIA to circumstances; FDEIA) in this paper, The diagnosis, pathophysiology and therapy of FDEIA are also reviewed.

The Effect of $\gamma$-PGA on NC/Nga Mice, a Mouse Model for Mite Antigen-induced Atopic Dermatitis (집먼지 진드기 항원으로 아토피 피부염을 유발한 NC/Nga 생쥐에 미치는 $\gamma$-PGA의 효과)

  • Jang, Soon-Nam;Kim, Kum-Lan;Yun, Mi-Young;Kang, Sang-Mo
    • Microbiology and Biotechnology Letters
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    • v.38 no.1
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    • pp.53-63
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    • 2010
  • As one of the mucous components of Cheonggukjang, traditional fermented soybean paste, $\gamma$-PGA is a natural substance with diverse functions. In this paper, an in-vivo experiment has been performed using NC/Nga mice in order to find out the efficacy of $\gamma$-PGA in human atopic dermatitis. The NC/Nga mice with BMAC-induced atopic dermatitis were administered $\gamma$-PGA (PGA-HM) with 300 kDa and low-molecular $\gamma$-PGA (PGA-LM), respectively. As a result, a significant decrease in clinical skin severity score was detected in the group that was administered PGA-LM. In terms of serum IgE levels, a significant decline was observed in PGA-LM, compared to the control group. The serum IgG1 levels also decreased more in PGA-LM than in the control group. However, no significant difference was observed in both groups. To witness the induction of $CD4^+CD25^+foxp3^+$ Treg cells, mRNA was sampled from the back of PGA-HM- and PGA-LM-administered NC/Nga mice with atopic dermatitis. In terms of the production amount of foxp3 mRNA, which was measured in real-time PCR, the group that was administered PGA-LM was twice as high as the control group. According to a biopsy on the skin on the backs of the mice, the experimental group was also far lower than the control group in terms of epidermis thickness, mast cell infiltration and the number of $CCR3^+$ cells. Therefore, it has been confirmed that the atopic dermatitis symptoms decreased more in the PGA-LM-administered NC/Nga mice than the PGA-HM-administered group by facilitating $CD4^+CD25^+foxp3^+$ Treg cells and suppressing the activity of eosinophils and production of IgE and pro-inflammatory cytokines.

Evaluation of Farm Lands located in Urban Area and Industrial Complex using Insect Diversity Indices (곤충 다양성 지수를 이용한 도시 및 공단지역 농경지 환경평가)

  • Choi, Young-Cheol;Kim, Jong-Gill;Choi, Ji-Young;Kim, Won-Tae;Shim, Ha-Sik;Park, Beong-Do
    • Korean journal of applied entomology
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    • v.46 no.3
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    • pp.363-373
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    • 2007
  • To evaluate environment of farm lands using indicator insects and evaluation indices, the insect abundance of which is one of the major criteria for the evaluation of agricultural environment of farm land in urban areas and industrial complex, three sites (Ansan, Daesan, Suncheon) were designated and monitored from 2004 to 2006. The flora of agricultural land was more than urban areas and industrial complex of that in three sites. Soil, water and air pollution of urban areas and industrial complex were more serious than those of agricultural land in three sites. Overall population of insects were high from June to August in the surveyed three sites. Collected insects in agricultural land were 12 order, 106 family and 166 species, those in urban areas were 11 order, 102 family and 148 species, and in industrial complex were 11 order, 100 family and 152 species. Species and population belonging to Coleoptera was dominant in the surveyed sites. The insect diversity indices of farm land were 2.36 in agricultural land, 1.92 urban areas and industrial complex. And agricultural environment of agricultural land was good, urban areas was common and industrial complex was poor. Based on the major criteria of evaluation items, the criteria were selected as diversity index over 2.1, insect indicator Pheropsophus javanus in agricultural land, diversity index 1.5-2.0, insect indicator Nephotettix cincticeps in urban areas, diversity index below 1.5, insect indicator Pagria signata in industrial complex.

Development of a deep-learning based tunnel incident detection system on CCTVs (딥러닝 기반 터널 영상유고감지 시스템 개발 연구)

  • Shin, Hyu-Soung;Lee, Kyu-Beom;Yim, Min-Jin;Kim, Dong-Gyou
    • Journal of Korean Tunnelling and Underground Space Association
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    • v.19 no.6
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    • pp.915-936
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    • 2017
  • In this study, current status of Korean hazard mitigation guideline for tunnel operation is summarized. It shows that requirement for CCTV installation has been gradually stricted and needs for tunnel incident detection system in conjunction with the CCTV in tunnels have been highly increased. Despite of this, it is noticed that mathematical algorithm based incident detection system, which are commonly applied in current tunnel operation, show very low detectable rates by less than 50%. The putative major reasons seem to be (1) very weak intensity of illumination (2) dust in tunnel (3) low installation height of CCTV to about 3.5 m, etc. Therefore, an attempt in this study is made to develop an deep-learning based tunnel incident detection system, which is relatively insensitive to very poor visibility conditions. Its theoretical background is given and validating investigation are undertaken focused on the moving vehicles and person out of vehicle in tunnel, which are the official major objects to be detected. Two scenarios are set up: (1) training and prediction in the same tunnel (2) training in a tunnel and prediction in the other tunnel. From the both cases, targeted object detection in prediction mode are achieved to detectable rate to higher than 80% in case of similar time period between training and prediction but it shows a bit low detectable rate to 40% when the prediction times are far from the training time without further training taking place. However, it is believed that the AI based system would be enhanced in its predictability automatically as further training are followed with accumulated CCTV BigData without any revision or calibration of the incident detection system.

The Utilization Rate of Community Health Practitioner Post by Some Rural Residents and Its Associated Factors (일부 농촌지역 주민의 보건진료소 이용도와 관련요인)

  • Lee, Woon-A;Ryu, So-Yeon;Park, Jong;Kim, Suk-Il;Kim, Ki-Soon
    • Journal of agricultural medicine and community health
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    • v.25 no.1
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    • pp.133-147
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    • 2000
  • To provide data for the improvement of primary health care through the study on the utilization rate of community health practitioner(CHP) post and its related factors toward some rural residents in Mooan County Chollanamdo, a questionnaire survey was made from 382 persons during August 1999. Comparison was made between persons at the seaside area under difficult transportation and persons at the railroad area under convenient transportation. The results are as follows: 1. For the last one year, 83.3% of seaside area residents and 67.0% of railroad area residents used CHP post. As the purpose of visit to CHP post at seaside area, 94.3% visited for medical care, 25.3% for chronic disease control and 22.2% for health counselling and 14.1% for chronic disease control. 2. By simple analysis, sex, age, marital status, educational level, residence area, distance from living village to CHP post, presence of chronic diseases, satisfaction with CHP and confidence on CHP were related significantly with the utilization of CHP post for the last one year. 3. By multiple logistic regression, statistically significant variables related with the utilization rate of CHP post for the last one year were analyzed as age, sex, residence area and distance from living village to CHP post.

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Evaluation of the Bactericidal Activity of Electrolyzed Water against Salmonella Typhimurium and Staphylococcus aureus on Perilla Leaves (전해수를 이용한 들깻잎 중 Salmonella Typhimurium과 Staphylococcus aureus의 저감화 효과 분석)

  • Kim, Se-Ri;Ryu, Kyoung-Yul;Lee, Myoung-Hee;Jung, Chan-Sik;Yoon, Yo-Han;Shim, Won-Bo;Kim, Ju-Hee;Kim, Byung-Seok;Yoo, Soon-Young;Kim, Doo-Ho;Yun, Jong-Chul;Chung, Duck-Hwa
    • Korean Journal of Food Science and Technology
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    • v.44 no.4
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    • pp.467-471
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    • 2012
  • This study was conducted to evaluate the bactericidal activity of weakly alkalic electrolyzed water (WEW) against Salmonella Typhimurium and Staphylococcus aureus on perilla leaves. The influences of organic matter, inform of bovine serum, and the ratio of WEW to perilla leaves on bactericidal activity of WEW were also examined. Treatment of these organisms with 25, 50, 75, and 100 ppm WEW was performed for 1 min, 3 min and 5 min, respectively. Higher bactericidal activity was observed after a treatment with 100 ppm WEW compared to a treatment with 25 ppm WEW by 0.7 $log_{10}CFU/g$. The bactericidal activity of WEW also decreased with increasing bovine serum concentration. At the ratio of 10:1 (WEW: perilla leave), levels of Salmonella Typhimurium and Staphylococcus aureus were only reduced by 0.57 and 0.79 $log_{10}CFU/g$, respectively. It is suggested that the removal of organic debris prior to application of sanitizers and treatment above the ratio of 25:1 (WEW: perilla leave) is needed in order to improve WEW activity.

Decomposition Characteristics of Non-Degradable Liquid Waste under High Temperature and High Pressure Conditions (고온 고압 조건에서의 난분해성 액상폐기물 분해 특성)

  • Lee, Gang-Woo;Shon, Byung-Hyun
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.8 no.6
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    • pp.1572-1578
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    • 2007
  • The specified wastes consist of waste acid, waste alkali, waste oil, waste organic solvent, waste resin, dust, sludge, infectious waste, and others. Among these specified wastes, a great portion is liquid phase wastes. The purpose of this study is to develop the high temperature and high pressure (HTHP) treatment system for decomposition of the liquid phase specified waste (LPSW). For this, we analyzed the physical and chemical properties of the LPSW such as density, proximate analysis, ultimate analysis, heating values, and designed 0.3 ton/day HTHP treatment system. The LPSW tested in this experiment were prepared by adding TCE(trichloroethylene) and toluene to liquid phase waste which was brought into the commercial waste treatment company. The average density of waste oil (25 samples), waste resin (5 samples), and waste solvent (12 samples) was 0.99 g/mL, 0.91 g/mL, and 0.93 g/mL, respectively. And the average lower heating value of waste oil, waste resin, and waste solvent was 8,294 kcal/kg, 5,809 kcal/kg, and 7,462 kcal/kg, respectively. The DRE (Destruction & Removal Efficiency) of TCE and toluene were 99.95% and 99.73% at atmospheric pressure conditions and that were 99.99% and 99.82% at pressurized conditions, respectively. These results showed that TCE/toluene mixtures were properly decomposed over about 99.73% of DRE by the HTHP treatment system and pressurized conditions were more effective to destroy those pollutants than atmospheric pressure conditions. Also these systems could be directly applied to industries which try to treat the liquid phase specified waste within the regulation limit.

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Electron Microscopic Study on the Rabbit Inferior Lacrimal Glands (토끼 아래눈물샘의 미세구조에 관한 전자현미경적 연구)

  • Park, Young-Hee;Ahn, E-Tay;Ko, Jeong-Sik;Park, Dae-Kyoon;Kim, Myeong-Soo;Park, Kyung-Ho
    • Applied Microscopy
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    • v.37 no.1
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    • pp.23-33
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    • 2007
  • The lacrimal gland are compound tubule-acinar glands. The main lacrimal function is the production of the aqueous layer, the thickest and major constituent of the precorneal tear film. The lacrimal gland also has an important function in the defense system of the ocular surface, forming a part of the conjunctival-associated hymphoid tissue. The ultrastructural characteristics of the lacrimal gland of the rabbit were described. The lacrimal tissues of rabbits were processed through the conventional techniques for transmission electron microscopy. The secretory portions consisted of three cell types: 1. Serous cells with electron dense secretory granules. 2. Seromucous cells containing variable moderately electron dense secretory granules with flocculent material. 3. Mucous rolls containing mucous secretory granules. The serous cells were situated at the basal portion of acini, and they contained electron dense granules of variable densities and sizes. The seromucous cells contained a few protein secretory granules and more mucous secretory granules. The mucous cells contained even fewer protein secretory granules and exclusively mucous secretory granules. The epithelium of the intralobular ducts showed secretory granules, junctional complexes, and large basolateral intercellular spaces with lateral folds. These study might be helpful in determining inter-relationships, similarities and differences among the orbital glands of various physiological or pathological conditions.

Characteristics of PM2.5 and PM10 Concentration in Pusan Area (부산지역 PM2.5와 PM10의 농도 특성)

  • Kim, Sang-Youl;Cheong, Jang-Pyo;Yi, Seung-Muk
    • Journal of Korean Society of Environmental Engineers
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    • v.22 no.6
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    • pp.1159-1170
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    • 2000
  • It is necessary to improve the ambient air quality through the proper treatment and control of pollutants by designating air pollutants to regulatory ones. Especially, human took a concern for particulate matters which raised visibility reduction, public health effects and injury of property for urban areas. In order to reduce the effect of particulate matters, we need to establish proper control strategies based on the concentration characteristics of particulate matters. In this study. to evaluate the characteristics of $PM_{2.5}$ and $PM_{10}$. thirty-eight samples of $PM_{2.5}$ and $PM_{10}$ were collected at Nam-Gu sampling site where continuous air monitoring system has been operated, from May, 1999 to November, 1999, and their concentrations for the mass and anion components($Cl^-$, $NO_3{^-}$, $SO_4{^{2-}}$) were analyzed. The important conclusions obtained in this study were as followings. Total average mass concentrations of $PM_{2.5}$ and $PM_{10}$ were 35.016 and $50.293{\mu}g/m^3$ respectively. and $PM_{2.5}/PM_{10}$ ratio was calculated 0.692. Total average concentrations of anion components in $PM_{2.5}$ were $1.581(Cl^-)$, $3.690(NO_3{^-})$ and $12.825(SO_4{^{2-}}){\mu}g/m^3$ and those in $PM_{10}$ were $2.471(Cl^-)$, $5.819(NO_3{^-})$ and $14.414(SO_4{^{2-}}){\mu}g/m^3$ respectively. From the correlations analysis. the correlation coefficient between mass concentration of $PM_{2.5}$ and $PM_{10}$ was calculated as 0.945. The correlation coefficients between $PM_{2.5}$ and anion components were analyzed as $Cl^-$(0.025), $NO_3{^-}$(0.788) and $SO_4{^{2-}}$(0.500) respectively, and the correlation coefficients between $PM_{10}$ and anion components were analyzed as $Cl^-$(-0.019), $NO_3{^-}$(0.806) and $SO_4{^{2-}}$)(0.535) respectively.

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Studies on Pathogenicity of Nosema bombycis Naegeli to Parents and Hybrid in the Silkworm (Bombyx mori L.) (원종 및 교잡종에 대한 미립자의 병원성에 관한 연구)

  • 김종수;김문협;채수군;임종성
    • Journal of Sericultural and Entomological Science
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    • v.14 no.2
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    • pp.81-92
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    • 1972
  • Studies on Pathogenicity of Nosema bombycis Naegeli are summarized as follows: 1. The mortality of the parents, Jam 103 and Jam 104, is remarkbly higher than that of the hybrid, Jam 103$\times$Jam 104, whereas there is no difference in the mortality between the parents. 3. In the mortality of the pathogen-concentration, it is increased in order of the following concentrations inoculated, 10$^{8}$ , 10$^{7}$ , 10$^{8}$ and 10$^{5}$ /ml. 3. In the mortality of each instar, it is high in order of 5th, 4th, 3rd, and 2nd instar. 4. In the interaction between the mortalities of the varieties and the concentrations, 1) The mortality shows no differences between the parents and the hybrid in the high concentration of 10$^{8}$ /ml. 2) The mortality of the hybrid is lower than that of the parents in the low concentration of 10$^{5}$ /ml, whereas no difference is found between the parents. 3) The interaction appears at the same level in the middle concentration of 10$^{6}$ /ml to the parents and of 10$^{7}$ /ml to the hybrid. 5. It was pointed out that active immunity depends upon the volume of antigen injection, immunizing period, and injection intervals. In this experiment, it is noticed that the optimum volume of injection is above 20ml and D is the best one of the four treatment (A.B.C.D.). 6. The immune sera indicate such a 12,800 high titer in the indirect method can be obtained from the D immunizing method. Silkworm tissues and N. bombycis spores show self-fluorescence, but it is able to distinguish it from the F.I.T.C. by using the U.V. filter. 7. The midgut epithelium is examined to be the first site of the tissues which are penetrated into and multiplied by the inoculation of the pathogen per os.

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