• Proceedings of the Korea Inteligent Information System Society Conference
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• 2000.04a
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• pp.435-442
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• 2000

만성질병, 식습관, 영양등 스트레스에 시달리는 현대인의 건강 상태를 파악하는 일은 매우 중요하며 또한 필요하다. 그러나 식이 섭취 평가는 많은 분야의 자료와 지식을 필요로 하기 때문에 손쉽게 일반인이 신뢰성 있는 평가는 얻기는 쉽지 않다. 본 연구는 식품, 영양, 조리, 만성질병, 식습관 등의 여러 전문 분야의 자료와 지식을 기반으로 한 웹 상에서의 영양 평가 시스템으로 '건강 관리를 위한 사이버 식생활 자가 진단 시스템(Cyber Food Self Diagnosis Program, 이하 Cyber-FSDP)'의 설계 및 구축에 관한 것이다. 바탕으로 한다. 초고속 통신망을 이용하여 사람들의 건강문제와 관련된 식생활 정보를 수집하고, 개인별 식생활을 사용자와 상호작용하게 온라인으로 평가·진단하여 이를 개선하고 궁극적으로는 만성질병 위험도를 감소시키고 건강을 증진시킬 수 있는 영양 및 만성 질병 평가 전문가 시스템을 구축한 사례에 대한 Web 응용 프로그램 개발을 소개하며, 개발환경으로는 서버를 엔터프라이즈 3000 Solaris 2.5.1을 사용했으며, DBMS는 IUS (Illustra Universal Server)를 사용하였고, APB(App Page Builder), JabaScript, HTML 등의 언어로 구현되었다.

• Proceedings of the KAIS Fall Conference
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• 2011.12a
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• pp.181-184
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• 2011

본 연구는 국내 성인들의 만성 피로증상과 건강행태와의 관련요인을 파악하기 위해 시도하였다. 자료수집은 2011년 6월 8일부터 2011년 7월 13일까지 서울에 소재한 종합병원 내과에 내원한 환자군 37명, 대조군 111명을 대상으로 설문 및 면접조사를 하였다. 연구결과는 첫째, 운동여부는 정기적으로 운동하는 경우 남성환자군은 26.7%로 대조군의 42.2%보다 낮았으며 여성환자군도 22.7%로 대조군의 31.8%보다 낮은 분포를 보였다. 둘째, 남성의 경우 사회적요인은 45.18배의 위험비를 보였으며 유의한 것으로 나타났다. 여성의 경우 신체적 요인은 237.1배, 가정적 요인은 140.6배의 위험비를 보였으며 유의하였다. 이러한 결과를 토대로 만성피로를 예방하기 위해서는 규칙적인 생활, 건전한 생활리듬을 유지하며 취미생활등을 통해 심신의 만성피로 스트레스를 해소하는 것이 중요할 것으로 본다.

• Journal of Korean Orthopaedic Sports Medicine
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• v.10 no.1
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• pp.35-40
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• 2011

Purpose: This study was performed to evaluate the diagnostic usefulness of ankle stress radiograph for evaluation of chronic lateral ankle instability. Materials and Methods: Among patients undergoing the modified-Brostrom procedure, 42 cases with complete rupture of the anterior talofibular ligament were enrolled in this study. Sixty Korean adults (120 cases) were recruited as the control group. Radiologic measurement of talar tilt and anterior talar translation was performed through stress radiographs using Telos device. We obtained the normal range of Korean adults, and used as a standard value for judgment of mechanical instability. We analyzed the sensitivity, specificity, positive and negative prediction value of ankle stress radiograph. Results: On ankle stress radiograph, normal range of talar tilt angle and anterior talar translation was below $8.3^{\circ}$, below 7.6mm. Talar tilt angle on varus stress radiograph showed 57% of sensitivity, 97% of specificity, 89% of positive and 86% of negative prediction value. Anterior talar translation on anterior drawer stress radiograph showed 69% of sensitivity, 97% of specificity, 91% of positive and 90% of negative prediction value. Conclusion: Ankle stress radiograph had a good specificity, positive and negative prediction value for the evaluation of mechanical instability. However it underestimated the mechanical instability of ankle joint. It must be remembered that normal stress radiograph does not exclude ankle instability.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.11 no.2
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• pp.252-261
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• 2000

Objectivity：This study was conducted to examine the depression, self-concept, perception of stress & coping strategy in children with chronic physical illness. Methods：Two groups of participants were recruited for this study, 13 children with chronic illness in outpatient or inpatient treatment at Seoul National University Children's Hospital, and 13 nonpatient children. They were assessed using Korean form of the Piers-Harris Self-Concept Scale (PHSCS), Kovacs' Children's Depression Inventory(CDI) and three subscaleds('color how you feel' 'color how others make you feel' 'A children in the rain' of Children's Self-Report and Projective Inventory(CSRPI). Result：There were significant differences between the chronic ill children and the healthy children in scores of depression and self-concept. The chronicity ill children were more depressive and had very negative self-concept, and obtained significantly lower scores than the healthy children in the subscales of PHSCS, 'intellectual/school status' and 'popularity' Among three scales of CSRPI, there was no difference in 'color how you feel' and 'color how others make you feel' But there were significant differences in all items of 'A child in the rain'(quantity of raining, duration of raining, tool, and effectiveness). 'Duration of raining' correlated most negatively with PHSCS scores, and correlated positively with CDI scores. Conclusion：The children with chronic illness are more depressive and have very negative selfconcept. And they feel that the stresses are more permanent, but have no appropriate coping strategy. The results suggest that the chronic illness strongly affects the psychological and emotional adjustment of children(i.e. depression, peer relation, stress coping strategy).

• Journal of the Korea Convergence Society
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• v.12 no.11
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• pp.359-369
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• 2021

In this study, a complex sample logistic regression analysis was performed to identify the factors affecting the activity restriction of 2,701 normal elderly and chronically ill elderly aged 65 and over using raw data from the 8th period of the National Health and Nutrition Examination Survey. It was found that the elderly with chronic disease felt more restricted in their activities than the normal elderly. Activity limiting factors in stroke and hypertension patients are subjective health status, economic level, stress perception, and moderate-intensity work and leisure. The factors limiting activity in patients with heart disease were subjective health status and economic level, and factors limiting activity in patients with joint disease were subjective health status and high-intensity work and leisure. Activity limiting factors for lung disease patients are education level, high intensity work and leisure, and endocrine system activity limiting factors include subjective health status, stress perception, high intensity work and leisure, and activity limiting factors for cancer patients. is subjective health status, stress perception, moderate-intensity work and high-intensity leisure. Rehabilitation programs and policy support are needed for the continuous participation of the elderly with chronic diseases.

• Tuberculosis and Respiratory Diseases
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• v.61 no.4
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• pp.330-338
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• 2006

Background: The main factors associated with weight loss in patients with COPD are not well known. Since chronic inflammation and oxidative stress play a major pathogenic role in COPD, these factors may be responsible for the patients' weight loss. Therefore, this study measured the body mass index (BMI) in COPD patients and evaluated the variables, such as systemic inflammatory marker, oxidative stress and lung function, that correlate with the BMI. Method: The stable COPD patients (M:F=49:4, mean age=$68.25{\pm}6.32$) were divided into the lower (<18.5), normal (18.5-25) and higher (>25) BMI group. The severity of the airway obstruction was evaluated by measuring the $FEV_1$. The serum IL-6 and TNF-$\alpha$ levels were measured to determine the degree of systemic inflammation, and the carbonyl protein and 8-iso-prostaglandin $F_2{\alpha}$ level was measured to determine the level of oxidative stress. Each value in the COPD patients and normal control was compared with the BMI. Results: 1) Serum 8-iso-prostaglandin $F_2{\alpha}$ in COPD patients was significantly higher ($456.08{\pm}574.12pg/ml$) than that in normal control ($264.74{\pm}143.15pg/ml$) (p<0.05). However, there were no significant differences in the serum IL-6, TNF-$\alpha$, carbonyl protein between the COPD patients and normal controls. 2). In the COPD patients, the $FEV_1$ of the lower BMI group was significantly lower ($0.93{\pm}0.25L$) than that of the normal BMI ($1.34{\pm}0.52L$) and higher BMI groups ($1.72{\pm}0.41L$) (p<0.05). The lower $FEV_1$ was significantly associated with a lower BMI in COPD patients (p=0.002, r=0.42). The BMI of very severe COPD patients was significantly lower ($19.8{\pm}2.57$) than that of the patients with moderate COPD ($22.6{\pm}3.14$) (p<0.05). 3). There were no significant differences in the serum IL-6, TNF-$\alpha$, carbonyl protein and 8-iso-prostaglandin $F_2{\alpha}$ according to the BMI in the COPD patients. Conclusion: The severity of the airway obstruction, not the systemic inflammatory markers and oxidative stress, might be associated with the BMI in stable COPD patients. Further study will be needed to determine the factors associated with the decrease in the BMI of COPD patients.

• Journal of the Korean Applied Science and Technology
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• v.41 no.2
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• pp.459-471
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• 2024

In modern society, where tension and stress are ubiquitous, individuals often experience psychological imbalances. These stressors not only affect mental well-being but also manifest physically, through the skin. Consequently, a new term psychodermatology combining psychiatry and dermatology, has emerged, garnerning attention and research focus. In this study, we aimed to develop materials improving chronic skin conditions caused by stress by utilizing a compound of Cucurbita moschata, Paeonia japonica, and Prunus cerasus known to alleviate skin disorders. We sought to develop and validate the efficacy of materials alleviating chronic skin conditions induced by stress in keratinocytes..Therefore, in this study we analyzed the effects of a complex extract using Cucurbita moschata, Paeonia japonica, and Prunus cerasus on HaCaT keratinocyte cells to understand how it influences them. The complex extract on HaCaT keratinocyte cells showed a concentration-dependent decrease in the expression levels of TNF-α, IL-1β, IL-6, MDC, and TARC at concentrations of 12.5, 25, 50 and 100 ㎍/mL. Particularly noteworthy was the efficacy observed in inhibiting IL-1β, with a reduction of over 40% at a concentration of 100 ㎍/mL. Additionally, the production levels of AQP-3, HA, and filaggrin exhibited a significant concentration-dependent increase. The protein expression of p-ERK, p-JNK, and p-p38, which were elevated by TNF-α/IFN-γ, was significantly decreased with the treatment of the complex extract. These findings suggest that the compound extract may be utilized as a material for treating and preventing skin conditions, potentially mitigating the adverse effects of the mutual relationship between skin disorders and stress.

• Proceedings of the Korean Aquaculture Society Conference
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• 2005.05a
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• pp.163-164
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• 2005

• The Monthly Diabetes
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• s.288
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• pp.51-57
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• 2013

당뇨병과 정신건강은 어떤 관련성이 있을까? 당뇨병이 스트레스나 우울증과 관련이 있다는 것은 비교적 잘 알려져 있는데 다른 정신건강 문제와도 관련이 있을까? 당뇨병을 꾸준히 관리하는 것만도 수월하지 않은 당뇨병 환자에게 정신건강 관리를 하라는 것은 또 다른 부담을 가중시킬 수 있을 것이다. 그러나 효과적인 당뇨병 관리를 위해서는 정신건강에 관심을 기울이고 함께 관리하지 않을 수 없다. 건강하고 안정적인 정신건강 상태는 당뇨병 관리의 뒷받침이 되므로 당뇨병의 효과적인 관리를 위해 선행되어야 할 요소이다. 종종 정신건강 문제는 당뇨병 관리의 방해요인이 되기 때문에 이를 방지하기 위해서도 정신건강 관리는 당뇨병 관리와 함께 이루어져야 한다. 스트레스, 우울, 불안 등 정신건강 문제들이 어느 정도 해결될 때, 비로소 당뇨병 자가관리를 지속할 수 있으며 그 효과를 거둘 수 있는 것이다. 대부분의 당뇨병 환자는 진단기준을 충족시키지는 않더라도 적어도 가끔은 정신장애 증상을 경험할 수 있다. 일부 환자는 진단기준에 부합하는 장기간의 심각한 정신과적 증상으로 고통을 받기도 한다. 당뇨병 진단 후 당뇨병을 심리적으로 수용하고 관리하는 과정에서 정신장애를 경험하게 될 가능성이 높아진다. 정신장애도 만성질환의 속성을 가지므로 정신장애를 동반한 당뇨병 환자는 만성질환 관리의 부담이 가중될 수 있다. 따라서 정신장애를 최대한 예방하고 적시에 적절한 치료를 통해 심화되지 않도록 하는 것이 중요하다. 이를 위해 당뇨병과 관련 있는 정신장애에 대한 이해와 지식을 갖추는 것이 필요하다.

• Korean Journal of Environmental Biology
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• v.18 no.4
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• pp.377-385
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• 2000

This study was carried out to investigate the ecotoxicological response on Gammarus sobaegensis Ueno with acid stress. Mean value of $LT_{50}$ (lethal time 50%) under pH 3 condition as acute ecotoxicity test was observed to be 0.271 ($\pm$0.146) day. And 0.812 ($\pm$0.377) day under pH 4, respectively. Mean value of $LT_{50}$ under pH 3 and 5 were 6.313 ($\pm$0.828), and 9.475 ($\pm$4.881) day, respectively. Variance in chronic ecotoxicity test pH (F ratio: 11.240, P< 0.0005) and times (F ratio: 2.916, P< 0.0005) as single factor were revealed to be the major factor for determining LT$_{50}$ with acid depression. The variation of secondary gill surface with acid stress to be certain that wrinkle phenomenon. Being weak tolerance of G. sobaegensis against the acid stress, it shows the possibility to be examined as an aquatic toxicity test organism.