• Journal of Chest Surgery
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• v.36 no.11
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• pp.874-877
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• 2003

Necrotizing bronchial aspergillosis usually occurs in the immumocompromised host. Aspergillus invades bronchial epithelium and forms endobronchial mass or endobronchial stenosis. A 78-year-old male patient with diabetus mellitus complaining of dyspnea and cough was admitted to our hospital. Plain chest X-ray and chest computed tomogram showed a large endobronchial mass and total collapse of left upper lobe of the lung. Bronchoscopic biopsy of the endobronchial mass revealed chronic inflammation. To confirm the endobronchial mass, we performed sleeve lobectomy of left upper lobe of the lung. Histologically the mass was diagnosed as necrotizing bronchial aspergillosis. We report a case of necrotizing bronchial aspergillosis in an elderly man who has diabetus mellitus with review of the literature.

• Tuberculosis and Respiratory Diseases
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• v.43 no.5
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• pp.812-817
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• 1996

There were so many causes of chronic coughing including postnasal drip, pneumonia, nasal polyp, asthma, interstinal lung disease etc. Congenital bronchoesophageal fistula was not usually thought as cause of chronic coughing. A 46-year-old female patient suffered from chronic coughing without usual causes. Her chest X-ray viewed normally. She coughed especially after swallowing foods. So we recommended her esophagogram and it revealed broncho-esphageal fistula. She underwent surgical resection of broncho-esophageal fistula. She was well without cough after the surgery. We reported a case of congenital broncho-esphageal fistula that had caused chronic coughing without any evidence of pneumonia, malignancy, tuberculosis, bronchiectasis, inflammation, asthma, nasal polyp, etc. So we should suspect the bronchoesophageal fistula when patients cough chronically with eating, and recommend the esophagogram.

• Journal of Veterinary Clinics
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• v.32 no.6
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• pp.523-526
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• 2015

A 9-year-old, castrated male Malamute dog was presented with chronic cough. On thoracic computed tomography, non-tapered and dilated peripheral bronchi were detected. Bronchoarterial ratio was about 2.2. The dilated bronchi appeared as a cluster of grapes especially in left cranial, left caudal and right middle lung lobe. Based on the computed tomographic findings, the diagnosis was made as the saccular type of bronchiectasis.

• The Journal of Korean Medical History
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• v.26 no.1
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• pp.19-26
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• 2013

There are many children suffering from chronic upper respiratory infections with high fever(CURIHF) for years. High fever mainly caused by tonsillitis comes from cold and flu season-related. Observing CURIHF children, they also have a night sweat(盜汗) and a thick voice, a chronic cough, a loss of appetite in common. I found that after administering the Daqinglong-tang(大靑龍湯) to the 6 CURIHF children, high fever was dropping quickly and did not recur for 233~733 days. Also, the symptoms of a night sweat(盜汗) and a thick voice, a chronic cough, a loss of appetite are improved significantly. These case report suggests that in case of CURIHF, Daqinglong-tang could effectively control recur of high fever in children.

• The Journal of Internal Korean Medicine
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• v.40 no.3
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• pp.557-565
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• 2019

Objectives: This study investigated the effect of local acupuncture point stimulation and the application of a topical herbal mixed heating cream in a chronic cough patient who had not responded to various medications for more than a few months. Methods: An 81 year-old female patient who was suspected to be suffered from Upper Airway Cough Syndrome (UACS) was examined. The patient was treated with local acupuncture point stimulation and the application of a topical herbal mixed heating cream. We used the Leicester Cough Questionnaire, Cough-Specific Quality-of-Life Questionnaire, and Verbal Numerical Rating Scale to assess the patient's respiratory symptoms. Results: Local acupuncture point stimulation and the application of a topical herbal mixed heating cream resulted in the improvement of cough symptoms. The quality of life due to the alleviation of symptoms also significantly improved. Adverse effects were not observed. Conclusions: This study suggests that local acupuncture point stimulation and the application of a topical herbal mixed heating cream may be an effective therapy for the treatment of chronic cough in patients with UACS.

• Herbal Formula Science
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• v.30 no.2
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• pp.101-108
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• 2022

Objectives : The prevalence of chronic cough in Korea is 2.5 ± 0.2% among people over the age of 40, and the rate of idiopathic chronic cough is high. Hemoptysis is one of the respiratory emergency symptoms, and the cause is unknown in 30% of cases. This case report is to confirm the treatment of korean medicine for Idiopathic chronic cough and hemoptysis. Methods : A 74 year old female patient with idiopathic chronic cough and hemoptysis was treated with korean medicine. The patient was treated from july 21, 2021 to september 24, 2021, using herbal medicine (Chungpyebyeolgab-sangagam) and acupuncture(Sa-Am Acupunture Lung Tonifying, CV22). Idiopathic chronic cough and hemoptysis were assessed by VAS. Results : Idiopathic Chronic cough and hemoptysis improved through Korean medicine treatment. Although taking codeine phosphate and transamin was stopped, the improvement of symptoms was maintained. Conclusions : This study suggests that korean medicine treatment may be an effective therapy for treatment of idiopathic chronic cough and hemoptysis.

• Tuberculosis and Respiratory Diseases
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• v.43 no.4
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• pp.637-644
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• 1996

Interstitial pneumonitis associated with interferon alpha therapy for chronic hepatitis C was first describe6 in 1994 by Kazoo et al In Japan. The mechanism of interstitial pneumonitis developed by interferon alpha was still unknown but immunologic, allergic of direct lung toxicity were suggested. We experienced a case of interstitial pneumonitis developed during interferon alpha therapy for chronic hepatitis C in a 52-year-old male patient. He was treated with 6 million units of interferon alpha intramuscularly 3 times per week for 4 weeks and noted progressive dyspnea and cough. These symptoms were subsided after 6 weeks' discontinuation of interferon alpha therapy. And so, he was retreated with 3 million units of interferon alpha 3 times per week for 8 weeks and felt dyspnea again. He was admitted to our hospital for further evaluation of progressive dyspnea. Arterial blood gas(ABG) values were $PaO_2$ 90.7 mmHg and $PaCO_2$ 31.9 mmHg, and antinuclear antibody(ANA) was negative. A chest X-ray film revealed diffuse reticulo-nodular shadows in bilateral lung fields, suggesting a diagnosis of interstitial pneumonitis. A marked increase in lymphocyte count and suppressor T cell were observed in bronchoalveolar lavage(BAL) fluid. Lymphocyte stimulation test with interferon alpha was positive. Interstitial pneumonitis was confirmed by transbronchial lung biopsy. After discontinuation of interferon alpha, we gave oral steroid in the condition that clinical symptoms were being improved gradually.

• Proceedings of the KOR-BRONCHOESO Conference
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• 1979.05a
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• pp.7.1-7
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• 1979

This paper was attempted to analyze 31 cases of fiberoptic bronchoscopy during the period of 8 months from October 1978 till February 1979 in the Chung-Ang University Hospital. The results were as follows; 1) Among 31 cases. 20 cases were male, 11 cases female. Sex ratio was 2 : 1. 2) In age distribution, 22 cases (70.1%) were in 4th-7th decade, and the other age groups showed relatively even distribution. 3) The chief complaints were hemoptysis (11 cases, 35.5%), coughing (9 cases, 29.0%), chest pain (6 cases, 19.4%), dyspnea (3 cases, 9.7%) and others (2cases, 6.5%). 4) In Gram staining of bronchial secretion, Gram (-) diplococci were in 12 cases (38.7%), Gram (+) cocci 10 cases (32.3%), Gram (+) rods 6 cases (19.4%)and Gram (-) rods 3 cases (9.7%). In culture of bronchial secretion, no growth were in 17 cases (54.8%). Neisseria group 6 cases (19.4%), Proteus and Klebsiella group 1 case (3.2%) and mixed group 3 cases (9.7%). In histopathological study, 11 cases (35.5%) revealed chronic bronchitis, 9 cases (29.0%) bronchogenic carcinoma, 3 cases (9.7%) chronic granulomatous disease and 2 cases (6.5%) no specific findings. In 6 cases biopsy specimens were too small to be examined histopathologically. 5) In diagnosis by bronchoscopic appearance and by laboratory examination of bronchoscopically removed specimens, 9 cases(29.0%) were primary carcinoma of bronchus, 6 cases (19.4%) chronic bronchitis, 4 cases (12.9%) pneumonia in the order of freguency

• Proceedings of the KOR-BRONCHOESO Conference
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• 1987.05a
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• pp.15.2-16
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• 1987

사성이란 후두의 발생기능에 장애가 있을 때 생기는 후두질환의 가장 대표적인 주증상으로 인간 문화의 발달에 병행되어서 대화에 의한 전달수단이 중요시되고 또한 암에 대한 인식이 높아져 사성을 호소하는 환자들이 많아지는 경향이 있다. 이에 저자는 1980년 1월부터 1984년 12월까지 이화여자대학교 의과대학 부속병원 이비인후과 외래에 내원한 신외래환자 총 24,949명 중 사성을 주소로 한 800명의 환자에 대하여 병력지를 기준하여 각 질환을 통계적으로 분석 검토하여 다음과 같은 성적을 얻었다. 1) 이비인후과 외래환자 총 24,949명중 사성환자는 800명으로 약 3.2%이었다. 2) 외래사성환자 800명중 남자 336명, 여자 464명으로 남녀비는 약 1 : 1.4이었다. 3) 질환별로는 급성 후두염 248예(31.0%), 만성 후두염 186예(23.3%), 성대결절 160예(20.0%), 성대폴립 90예(11.3%), 성대마비 56예(7.0%), 후두 유두종 12예(1.5%), 후두암 9예(1.1%)이었다. 4) 연령별로는 30대가 213예(26.6%), 20대가 190예(23.8%), 40대가 179예(22.4%)의 순이었다. 5) 각 질환별 최다연령은 급성 후두염 30대 73예(29.4%), 만성 후두염 30대 53예(28.5%), 성대결절 30대 52예(32.5%), 성대폴립 40대 26예(28.9%), 성대마비 40대 14예(25.0%), 후두암 50대 6예(66.7%)이었다. 6) 발병부터 초진까지의 기간은 10일 이내가 153예(19.1%)로 제일 많았고 1개월∼3개월 138예(17.3%), 11일∼l개월 119예(14.9%)의 순이었다. 7) 각 질환에 따른 발병부터 초진까지의 기간의 최다분포는 급성 후두염은 10일 이내가 117예(47.2%), 만성 후두염은 3개월∼6개월이 44예(23.7%), 성대결절은 3개월∼6개월이 40예(25.0%), 성대폴립은 6개월∼1년이 20예(22.2%), 성대마비는 10일이내가 12예(21.4%)이었다. 8) 질환별 동반증상 분포는 사성만을 호소한 경우가 394예(41.4%)로 가장 많았고 동반증상으로는 인두통, 이물감, 객담, 기침, 연하장애, 호흡곤란의 순이었다. 9) 저자의 연도별 사성환자의 평균발생빈도(3.2%)를 문(1981)의 1975년 1월부터 1979년 12월(만 5년간)까지의 평균발생빈도(2.9%)와 비교할 때 증가하였다.

• Tuberculosis and Respiratory Diseases
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• v.49 no.4
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• pp.432-440
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• 2000

Background : The prevalence of pulmonary tuberculosis among the elderly is increasing in Korea and in the developed countries due to the increased elderly population and their predispositions to chronic disease, poverty and decreased immunity. To define the characteristics of pulmonary tuberculosis in the elderly, we evaluated the clinical spectrum of pulmonary tuberculosis. Method : We analyzed 92 patients retrospectively that were diagnosed as active pulmonary tuberculosis over the age of 65. The analysis involved patient's profiles, clinical manifestations, coexisting diseases, diagnostic methods, anti-TB medications and their side effects, and treatment outcomes. Results : The results were as follows : - 1) The ratio of male to female was 2.1:1(62:30 cases) 2) Chief complaints were a cough (47.8%), dyspnea (40.2%), sputum (38.0%), chest pain (12.0%), anorexia (10.9%), and fever (9.8%). 3) 38 (41.3%) of cases had a past history of pulmonary tuberculosis. 4) The coexisting diseases were : -COPD, 25 cases (27.2%); pneumonia, 17 cases (18.5%); DM. 13 cases (14.1%); and malignancy, 10 cases (10.9%). 5) The positivity of Mantoux test (5 TU, PPD-S) was 82.7%. 6) Pulmonary tuberculosis was diagnosed using the following methods : sputum AFB (Acid Fast Bacillus) smear 42.4%, sputum TB (M. Tuberculosis) culture 15.2%, sputum TB PCR (Polymerase Chain Reaction) 10.9%, bronchial washing AFB smear 2.1%, chest radiology only 25.0%. 7) Locations of radiologic lesions were RULF, 50 cases; RLLF, 50 cases, mostly, then LLLF ; 26 cases were leastly involved. 8) The coexisting tuberculosis were endobronchial TB(8.7%), TB pleurisy(7.6%) miliary TB(5.4%), intestinal TB(2.2%), renal TB(1.1%) 9) The proportion of treatment regimen with 1st line drug and 2nd line drug were 92.3% and 7.6%, respectively. 10) The outcome of treatment were as follows : cured 31.5%, expired 13.0%, no return 47.8%, follow-up now 7.6%. Conclusion : The pulmonary tuberculosis in the elderly has atypical patterns with chronic coexisting diseases. Therefore, the possibility of pulmonary tuberculosis should be considered in elderly patients with pulmonary symptoms.