• The Journal of Korean Academic Society of Nursing Education
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• v.9 no.2
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• pp.253-263
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• 2003

Rheumatoid arthritis patients not only suffer from the physical damage, but they are afflicted severely mental and psychologic after effects. Their depression and low self-esteem eventually yields serious mental damages, which makes difficult for them to recover. The states of mental health of arthritis patients are diversified depending on the characters and surrounding circumstances, although they may have suffered from the similar condition. Therefore this research was conbucted to the factors that can give positive influences to the patients. In recent time, social support for the arthritis patients has become an important factor that can positively influence their mental health. In other words, social support can act as an important environmental system for arthritis patients to recover their damaged mental health. In order to fulfill this purpose, 118 patients were examined to identify the relationship between the variables. The summary of the result obtained from the research is as follow: 1. The structural aspect of social support for arthritis patients showed the most of them had various social support network size and their highest support system were 'family', 'relative' and 'friends'. The functional aspect of social support for arthritis patients showed moderate degree and their highest sub component was 'approval'. 2. High correlation was found between duration of relationship, similarity, frequency of meeting and functional support. There was no relationship between depression, self-esteem and social support. 3. Therefore this research has suggested that nurses who care rheumatoid arthritis patient consider the above condition to develop self-help group.

• Korean Journal of Adult Nursing
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• v.14 no.2
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• pp.213-221
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• 2002

Purpose: The aim of this study was to investigate the difference of in the level of pain, depression, and quality of life by coping strategy in the chronic arthritis patients. Method: These data were collected by means of a self-reported questionnaire from 90 chronic arthritis patients undergoing treatment at a university hospital in Daegu city from June 10, 2000 to July 15, 2000. The instruments of study were coping strategy scale by Jeon(1985), pain scale by Lee and Song(1987), depression scale by Radloff(1977) and quality of life scale by Cho(1987). Data analysis was done by SPSS Win 10.0 program and Pearson correlation, t-test, Cronbach's-${\alpha}$ were used. Result: The results of this study were as follows: 1. The item mean score of pain for chronic arthritis patient was 6.54. The item mean score of depression for chronic arthritis patient was 2.18. The item mean score of quality of life for chronic arthritis patient was 5.69. 2. The chronic arthritis patients with problem-focused coping experienced pain higher than those with emotion-focused coping(t=o.400, p=o.o45). The chronic arthritis patients with emotion-focused coping experienced depression higher than those with problem-focused coping(t=-2.564, p=0.012). The chronic arthritis patients with problem-focused coping experienced quality of life higher than emotion-focused coping(t=-1.682, p=0.046). Conclusion: In conclusion this study showed that any coping strategy can control the arthritis patient's problem. Therfore, The development of a coping strategy to reduce pain and depression and improve the quality of life in the chronic arthritis patient will be needed.

• Journal of Acupuncture Research
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• v.22 no.4
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• pp.55-63
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• 2005

목적 : 만성 염증성 질환에 대한 전침효과를 알아보기 위해 complete Freund's adjuvant (CA) 유발 관절염 모델에서 염증관련 단백질의 변화를 살펴보았다. 방법 : Sprague-Dawley계 흰쥐의 족부에 CFA를 주사한 다음 3일 간격으로 2 Hz, 15 Hz 및 120 Hz 전침 자극을 주며 부종 형성여부를 plethysmometer로 측정하여 판정하였으며 30일 째 거퇴관절을 취하여 4% paraformaldehyde에 고정하고 EDTA용액에서 탈회시켜 파라핀연속 절편을 얻어 $NF-{\kappa}B$를 비롯한 5종의 염증관련 단백질의 발현을 면역조직화학적으로 살펴보았다. 결과 : 관절연골내 면역반응 중 연골기질은 반응이 없거나 약하고 연골세포는 $NF-{\kappa}Bp65,\;I-{\kappa}B{\alpha},\;iNOS$반응이 강하며 특히 유리연골층에서 더 현저하였으나 염증 및 전침자극에 따른 변화는 없었다. 관절낭에서 면역반응을 살펴보면 염증유발시 활액세포의 면역반응세포는 $I-{\kappa}B{\alpha}$가 감소한 반면 iNOS, $IL-1{\beta}$는 증가하며 특히 iNOS 증가가 현저하였으며 전침자극에 의해 iNOS가 감소하였다. 활액막조직에서 모든 면역반응이 증가하며 특히 $NF-{\kappa}Bp65,\;I-{\kappa}B{\alpha},\;iNOS$ 반응이 현저한데 전침자극에 의해 $IL-1{\beta}$를 제외한 모든 반응이 감소하였다. 결론 : 만성 염증성 동물모델의 거퇴관절 내 염증관련 단백질은 관절연골보다 관절낭에서 큰 변화를 보이며 전침처치에 의해 이들 단백질 발현이 억제되는 것으로 보아 전침이 만성 염증성 질환에 효과적임을 알 수 있다.

• Korean Journal of Acupuncture
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• v.28 no.1
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• pp.79-89
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• 2011

호장근(Polygonum cuspidatum Sieb et Zucc.)은 관절통, 만성 기관지염, 황달, 월경분순, 고협압 등의 치료제로 사용되고 있는 약물로서, 본 연구에서는 흰쥐의 류마티스 관절염 병태모델에서 호장근 약침이 류마티스 관절염에 미치는 영향에 대해 관찰하였다. 방법 : 본 연구에서는 bovine type II collagen으로 유발된 흰쥐의 류마티스 관절염 병태모델에서 인체의 족삼리(ST36)에 상응하는 부위에 호장근 약침액을 주입한 후, 체중변화, 족부종의 변화, 족근관절폭의 변화, cytokine의 변화, NOS 발현 양상 등을 관찰하였다. 결과 : 족부종 감소율은 고농도 호장근 약침군에서 높았고, 족근관절폭 감소율은 고농도 및 저농도 호장근 약침군에서 대조군에 비하여 유의하게 높게 관찰되었다. 족부 삼출물 내의 TNF-${\alpha}$ 함량은 고농도 호장근 약침군에서 높았고, IL-$1{\beta}$ 함량은 고농도 및 저농도 호장근 약침군에서 대조군에 비하여 유의하게 높게 관찰되었다. 대뇌 피질에서 NOS 양성 신경세포수는 고농도 및 저농도 호장근 약침군에서 대조군에 비하여 유의하게 낮게 관찰되었다. 결론 : 이상의 결과에서 호장근 약침은 type II collagen으로 유발된 흰쥐의 류마티스 관절염 병태모델에서 염증 반응을 억제하는 효과가 있는 것으로 사려된다.

• Physical Therapy Korea
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• v.7 no.4
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• pp.16-38
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• 2000

일상생활동작(activities of daily living)을 주요 목적이자 치료 수단으로 사용하고 있는 작업치료사들이 그 활동 중의 하나인 성적 욕구의 표현(sexual expression)에 대해 체계적인 접근이 미진하다는 지적을 극복 하고자 본 연구가 계획되었다. 특히 만성 장애가 있는 65세 이상 연령층의 성생활에 대해 기술적으로 접근하는 방법을 고안하는 것은 상당한 임상적 의미를 부여 할 수 있다. 본 연구의 주된 목적은 관절염이 65세 이상의 미국인의 성생활에 미치는 영향과 대책에 대한 논의를 작업치료사의 입장에서 자연스럽게 유도하기 위한 질문내용을 고안하는데 있다. 본 연구자들은 광범위한 문헌연구를 바탕으로 7개항의 질문을 작성하여 10명의 노인학 전공 작업치료사들에게 비평을 의뢰하였다. 7명의 작업치료사들이 전문가로서의 세밀한 답변을 해주었고 그들은 공통적으로 일상생활 중의 하나인 성생활이 삶의 질을 향상시키는데 매우 중요한 역할을 함을 강조하였다. 이들 전문가들의 조언을 바탕으로 새로운 질문서가 완성되었다.

• Journal of Oral Medicine and Pain
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• v.38 no.3
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• pp.247-253
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• 2013

Renal osteodystrophy(RO) is characterized by skeletal changes in patients with renal disease and developed as a result of alterations in the metabolism of calcium, phosphate and secondary hyperparathyroidism. Bony changes in the craniofacial region include decreased bone density, radiolucent lesions(brown tumors), depletion of cortical bone and loss of lamina dura, but such changes rarely occur in the temporomandibular joint(TMJ). We report an uncommon case of bony changes and pain of both TMJs in a patient with RO. A 41-year-old man with RO came to our clinic due to TMJ pain and sounds. Occlusal change was also reported. Radiographs revealed degenerative changes of the both condyles. The patient had medical history of renal cancer therapy and hemodialysis. The patient was diagnosed with TMJ arthritis of RO and referred for systemic management through medication of calcium and vitamin D and parathyroidectomy. At 15-month follow-up, most of TMD symptoms disappeared and second radiographs revealed that bone density and cortical thickness of the mandible increased and the skeletal outline of the both condyles became relatively clear. As bony changes may begin in the early stage of the renal disease, dentists should be alert to detect the sign of the disease. In addition, it is important to differentiate TMJ arthritis of systemic cause because the treatment protocol is quite different.

• Korean Journal of Clinical Laboratory Science
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• v.47 no.4
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• pp.168-174
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• 2015

Rheumatoid arthritis (RA) is a chronic inflammatory disease, which is mainly characterized by disease of joints affected with synovial hyperplasia, pathological immune response, and progressive destruction; all of which represent an important social health problem. These provide new insights in its pathogenesis of rheumatoid arthritis diagnosis and disease progression in molecular changes. This review focuses on new serological and immunological markers which seem to be useful in early diagnosis and prognosis of rheumatoid arthritis. Therefore, such tests are widely conducted for serological biomarkers and the developments with such immunological factors to identify patients who are at risk for disease progression. This evidence of the disease based on laboratory medicine could provide the best outcome for patients. Finally, data from recent studies will help to refine the ultimate usefulness of this novel approach for early diagnosis, treatment, and helping clinicians to optimize therapy by using this approach.

• Proceedings of the EASDL Conference
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• 2003.04a
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• pp.81-82
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• 2003

국민소득 증대에 따른 사회경제 수준의 향상과 의학발달에 의해 평균 수명이 연장되었다. 이로 인한 인구의 노령화로 노인관련 질환 즉, 류마티스성 관절염, 심장질환 등과 같은 만성 퇴행성질환과 암 등 영양섭취의 불균형과 관련된 질병이 급증되었다. 최근 ROS(reactive oxygen species), PGs(prostaglandins), 및 NO(nitric oxide)가 각종 염증성 질환, 순환계 질환 및 암화 과정에 밀접한 연관이 있기 때문에 이들을 조절할 수 있는 식품류가 각종 질환의 예방을 목적으로 각광을 받고 있다.(중략)

• Journal of Naturopathy
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• v.8 no.2
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• pp.53-62
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• 2019

Purpose: To investigate the healing effect of 21 patients with chronic back pain, shoulder pain, and knee arthritis by a Qigong. Methods: The study performed by hand injection of a Soojung Qi-therapy. Results: Ten patients (47.6%) had low back pain, eight (38%) had frozen shoulders, and three (14.3%) had knee arthritis. Satisfaction after five times of the Qi-healing was 72% in those who returned to normal and 14% in those who improved. When the maximum pain level set at 5.0, the difference between before and after healing was 3.33 in arthritis subjects, 3.75 in fifty shoulder subjects, and 3.80 in low back pain. In general, the degree of pain decreased as the number of healings increased. In particular, even after the first healing, the pain reduction of the subjects was high in arthritis, frozen shoulders, and low back pain. That is, there was a possibility of controlling pain with only one Qi-healing. Conclusions: Soojung Qi-therapy is one of the natural healing treatments because it reduces fast pains and accessible to handling anytime and anywhere. Conclusions: With Qi-therapy, arthritis, frozen shoulder, and lumbago patients almost recovered to their original shape. Therefore, Qi-therapy regarded as one of the useful natural healing therapies.

• Journal of muscle and joint health
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• v.6 no.1
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• pp.73-84
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• 1999

This study was conducted to identify the characteristics of fatigue and its influencing factors in patients having chronic arthritis. The subjects of this study were 120 patients who visited a Rheumatis Center of H University Hospital. Data were collected from Aug. 9, 1997 to Feb. 5, 1998. For analysing data, SPSS/Win was used for descriptive statistics & Pearson's correlation coefficient, and Lisrel 8.0 was for path analysis. The findings were as follows : 1. Mean score of subjective fatigue was 5.36 and it means moderate degree of fatigue. 2. Fatigue showed positive relationship with pain & depression, and it showed negative relationship with ADL & self efficacy. 3. Fatigue was influenced by pain and depression. and was not influenced by ADL and self efficacy directly. But ADL and self efficacy influenced on fatigue through pain and depression indirectly. According to this findings. the significant influencing factors of fatigue were pain and depression, therefore the development of nursing intervention for relieving pain and depression would be needed.