• 대한방사선방어학회:학술대회논문집
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• 2011.04a
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• pp.82-83
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• 2011

• 대한두경부종양학회:학술대회논문집
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• 2001.11a
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• pp.252-252
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• 2001

• 대한세포병리학회:학술대회논문집
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• 1993.06a
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• pp.27-27
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• 1993

• 대한세포병리학회:학술대회논문집
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• 1992.11a
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• pp.16.2-17
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• 1992

• Proceedings of the Korean Society of Veterinary Clinics Conference
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• 2006.11a
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• pp.47-47
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• 2006

• Radiation Oncology Journal
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• v.20 no.4
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• pp.303-308
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• 2002

Purpose : To determine the optimal radiation dose in a localized non-Hodgkin's lymphoma of the head and neck in the treatment setting for combined chemoradiotherapy. Materials an Methods :Fifty-three patients with stage I and II diffuse large ceil non-Hodgkin's lymphoma of the head and neck, who were treated with combined chemoradiotherapy between 1985 and 1998 were retrospectively reviewed. The median age was 49 years, and the male-to-female ratio was approximately 1.6. Twenty-seven patients had stage 1 disease and 26 had stage II. Twenty-three patients had bulky tumors $(\geq5\;cm)$ and 30 had non-bulky tumors (<5 cm). The primary tumors arose mainly from an extranodal organ $(70\%)$, most cases involving Waldeyer's ring $(90\%)$. All patients except one were initially treated with $3\~6$ cycles of chemotherapy, which was followed by radiotherapy. Radiation was delivered either to the primary tumor area alone $(9\%)$ or to the primary tumor area plus the bilateral neck nodes $(91\%)$ with a minimum dose of 30 Gy $(range\;30\~60\;Gy)$. The failure patterns according to the radiation field were analyzed, and the relationship between the dose and the in-field recurrence was evaluated. Results : The 10-year overall survival and the 10-year disease free survival rates were similar at $75\%\;and\;76\%$, respectively. A complete response (CR) after chemotherapy was achieved in 44 patients $(83\%)$. Subsequent radiotherapy showed a CR in all patients. Twelve patients $(23\%)$ had a relapse of the lymphoma after the initial treatment. Two of these patients had a recurrence inside the radiation field. No clear dose response relationship was observed and no significant prognostic factors for the in-field recurrences were identified because of the small number of in-field recurrences. However, for patients with tumors <5 cm in diameter, there were no in-field recurrences after a radiation dose 30 Gy. The 2 in-field recurrences encountered occurred in patients with a tumor $\geq5\;cm$. Conclusion .A dose of 30 Gy is sufficient for local control in patients with a non-bulky (<5 cm), localized, diffuse large cell non-Hodgkin's lymphoma when combined with chemotherapy. An additional boost dose in the primary site is recommended for patients with bulky tumors $(\geq5\;cm)$.

• Korean Journal of Head & Neck Oncology
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• v.31 no.1
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• pp.43-46
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• 2015

The Mantle cell lymphoma(MCL) is a relatively rare subtype of malignant lymphoma characterized by chromosomal translocation t(11 ; 14)(q13 ; q32), positive response for CD5, and nuclear cyclin D1. It is account for an estimated 3-6% of all non-Hodgkin's lymphoma. The involvement of extra-nodal site is not uncommon, whereas salivary glands are rarely affected. It is more commonly occurred in men and old age and approximately 75% of cases are diagnosed with advanced stage. It is usually characterized by an aggressive clinical course, and the prognosis is poorer than other type of head and neck lymphoma. We recently encountered a 69-year-old female with mass in parotid tail and upper neck, and it was diagnosed as mantle cell lymphoma. We report the unique case with a review of literature.

• Korean Journal of Head & Neck Oncology
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• v.31 no.1
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• pp.31-33
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• 2015

The extranodal non-Hodgkin lymphoma is uncommonly occurred in larynx, accounting for less than 1% of all laryngeal neoplasm. In general, the laryngeal lymphoma is appeared as submucosal mass without mucosal ulceration and is most commonly found in supraglottis. The primary laryngeal lymphoma constitute a diagnostic challenge because they are characterized by absence of clinical and gross differential criteria, compared with squamous cell carcinoma (SCC). We encountered a 74-year-old man with hoarseness and lump sensation in the throat. On direct laryngoscope, multiple ulcerative and exudative mass in glottis and supraglottic areas were observed. The patient was finally diagnosed as large B-cell lymphoma through the laryngeal microsurgery. He received radiation therapy and there is no evidence of recurrence. Although the laryngeal mass has superficial mucosal change, primary laryngeal lymphoma must be included in the differential diagnosis.

• The Journal of Korean Society for Radiation Therapy
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• v.14 no.1
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• pp.95-99
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• 2002

I. 목적 : 결막 림프종 환자의 전자선 치료를 위해 Lens shielding block의 제작시 외부 의뢰 제작과 SMC 자체 제작의 장${\cdot}$단점을 비교해보고 제작 과정에 있어 업무의 효율성을 평가하고자 한다. II. 대상 및 방법: Lens shielding block의 제작시 외부의뢰제작과정과 자체 제작 과정을 비교하여 업무의 효율성, 인력의 변화 및 두방법의 장?단점을 분석하였다. 모의치료후 두 방법의 제작 시간을 비교하였으며, 재료의 차이점과 이용방법을 비교하여 개선된 사항을 알아보았다. III. 결과 : Lens shielding block의 자체 제작시 치료 시작시기는 모의치료 실시 후 7일에서 3일로 단축되어 업무의 효율성과 그에 따른 환자의 불편함이 줄어들게 되었다. 또한, 외부의뢰 제작 과정에서 실시되었던 치과와 치과 기공실에 의뢰하던 과정이 없어지고 과내 모의치료실과 공작실에서 작업하게 되어 모든 작업을 과내에서 일률적으로 실시할 수 있게 되었다. 또한, 모의치료를 실시하면서 실시간으로 shielding block을 수정 할 수 있어 정확성이 재고되었고, 반복되는 제작 작업으로 인해 제작 공정이 보편화되고, 손쉬어졌으며, 재료 활용의 효율성이 증대되었다. IV. 결론 : Lens shieiding block의 자체 제작으로 시간이 단축되어 업무의 효율성이 증대되었고 그에 따른 인력소모와 환자의 불편함이 줄어들게 되었으며, 제작자가 모의치료를 통해 바로 block의 오차를 수정할 수 있어 치료의 안정성 및 정확성이 높아졌으므로 결론적으로 의료의 질 개선과 서비스 향상이 이루어졌다.

• Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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• v.24 no.2
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• pp.118-121
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• 2013

Primary lymphoma of the larynx is rare, accounting for less than 1% of all laryngeal neoplasm. Early symptoms are ambiguous and nonspecific, and confirmation of the diagnosis is often difficult. The aim of this study was to report the experience of our department in the management of these aggressive lesions, as they require special diagnostic and therapeutic attention. We enrolled 3 patients who diagnosis of lymphoma involving the larynx were retrospectively reviewed. The histopathological diagnosis revealed 1 case of diffuse large B cell lymphoma, and 2 case of NK-T cell lymphoma. Details of the presentation, diagnostic procedures, treatment, and outcome of these patients were presented. Primary laryngeal lymphoma is a rare entity. Early symptoms are subtle and nonspecific, and confirmation of the diagnosis is often difficult. Because of the rarity of this tumor type, the optimal management remains controversial and it seems that should be managed not as a distinct disease entity but as an unusual presentation of non-Hodgkin lymphoma, according to the recent treatment trends.