• Title/Summary/Keyword: 디에피

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Equilibrium, Isotherm, Kinetic and Thermodynamic Studies for Adsorption of 7-Epi-10-deacetylpaclitaxel from Taxus chinensis on Sylopute (실로퓨트에 의한 Taxus chinensis 유래 7-에피-10-디아세틸파클리탁셀의 흡착에 대한 평형, 등온흡착식, 동역학 및 열역학적 특성)

  • Park, Sae-Hoon;Kim, Jin-Hyun
    • Korean Chemical Engineering Research
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    • v.58 no.1
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    • pp.113-121
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    • 2020
  • In batch experiments, the adsorption of 7-epi-10-deacetylpaclitaxel was studied using Sylopute. Experimental equilibrium data were applied to Langmuir, Freundlich, Temkin and Dubinin-Radushkevich isotherm models. Among the four isotherm models tested, the Langmuir isotherm model gave the highest accuracy. The adsorption capacity was found to decrease with increases in temperature and the adsorption of 7-epi-10-deacetylpaclitaxel onto Sylopute was a favorable physical process. Adsorption kinetic data agreed very well with the pseudo-second-order kinetic model, while boundary layer diffusion and intraparticle diffusion did not play a key role in the adsorption process. The process of 7-epi-10-deacetylpaclitaxel adsorption onto Sylopute was exothermic and nonspontaneous. Also, the adsorption isosteric heat was independent of surface loading indicating an energetically homogeneous adsorbent.

Formation and Growth of Epitaxial $CoSi_2$ Layer by Reactive Chemical Vapor Deposition (반응성 화학기상증착법을 이용한 에피택셜 $CoSi_2$ 박막의 형성 및 성장에 관한 연구)

  • Lee, Hwa-Seong;Lee, Hui-Seung;An, Byeong-Tae
    • Korean Journal of Materials Research
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    • v.10 no.11
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    • pp.738-741
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    • 2000
  • Univorm epitaxial $CoSi_2$layers have been grown in situ on a (100) Si substrate at temperatures near$ 600^{\circ}C$ by reactive chemical vapor deposition of cyclopentadienyl dicarbonyl cobalt, (Co(η(sup)5-C(sub)5H(sub)5) ($CO_2$). The growth kinetics of an epitaxial $CoSi_2$layer on al Si(100) substrate was investigated at temperatures ranging from 575 to $650^{\circ}C$. In initial deposition stage, plate-like discrete $CoSi_2$spikes were nucleated along the <111> directions in (100) Si substrate with a twinned structure. The discrete $CoSi_2$plates with both {111} and (100) planes grew into an epitaxial layer with a flat interface on (100) Si. For epitaxial $CoSi_2$growth on (100) Si, the activation energy of the parabolic growth was found to be 2.82 eV. The growth rate seems to be controlled by the diffusion of Co through the $CoSi_2$layer.

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A Study for the MPEG-4 Library to operate in real-time on the DSP (DSP상에서 실시간 처리 가능한 MPEG-4 Library에 관한 연구)

  • Hong, Sung-Hwa;Jung, Suk-Yong
    • Journal of the Korea Convergence Society
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    • v.2 no.1
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    • pp.7-13
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    • 2011
  • Informations of multimedia centering in the images, are combined acoustic and letter, etc. Although the network advances and the capacity of the storage media extends, these huge informations will not be able to accommodate. From meaning which is like this, International standards for the compression and a multiplexing of image, acoustic and voice H261 where admits standard, JPEG, JBIG, MPEG-l, MPEG-2, MPEG-4 and H263, G series etc, are core techniques of multimedia. At initial step of the base technique which creates the base of like this multimedia service time, we developed the real-time MPEG-4 transmission systems to provides real-time MPEG-4 multimedia services. This system means becomes the base technique which hereafter is developed and is applied various system. This system Will be able to apply from a videoconference, a building protection system and a VOD video system to use the Internet. And, They, the image sensing, embedded linux, and MPEG4 software, will become sourceful technique to develop the different system.

The Effects of 12week Line Dance on dementia and Aging-related factors in Elderly Women (12주간 라인댄스가 노인여성의 치매 및 노화관련인자에 미치는 영향)

  • kim, Ji-won;soon, A-rum;Kim, Chan-hoi
    • Journal of the Korea Convergence Society
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    • v.10 no.6
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    • pp.243-249
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    • 2019
  • This study was conducted on elderly women in their 60s and 70s, and the results of the study were as follows when line dancing for 60 minuctes every three times a week for 12 weeks on dementia and aging-related hormones. After 12 weeks of line dancing programs, BDNF, DHEA-s, and estrogen increased, but no statistically significant differences with control groups emerged. In addition, after 12 weeks of line dancing, Apolipoprotein B decreased in line dancing group but showed no statistically significant difference from control group. Although significant differences between groups were not identified in the results of this study, positive effects on preventing and aging of dementia were identified in the group applying the line dance program, and further studies considering the new target and hign kinetic strength, frequency, time, and athletic genre are needed to identify the distinct effects of line dancing in the future.

Opioids Use and Adrenal Insufficiency (마약성 진통제 사용과 부신기능부전)

  • Jung, Ji Hoon;Choi, Youn Seon;Kim, Jung Eun;Kim, E Yeon
    • Journal of Hospice and Palliative Care
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    • v.17 no.3
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    • pp.113-121
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    • 2014
  • The major symptoms of terminally ill cancer patients are fatigue, loss of energy, feeling of helplessness, poor appetite and pain as well as general weakness, which are very similar to symptoms of adrenal insufficiency. Adrenal insufficiency-induced symptoms widely vary from mild symptoms to life-threatening conditions and may be resulted from variable medical causes. For terminally ill cancer patients who are hospitalized for palliative care, opioid agents are prescribed to control moderate to severe pain. The use of acute or chronic opioid agents is believed to negatively affect adrenal gland function. In most studies of opioid effects (preclinical/clinical with animal subjects or and patients suffering non-malignant pain, adrenal insufficiency and hormonal abnormalities were observed as side effects. However, opioid-induced adrenal insufficiency has been rarely reported in studies with patients with malignant cancer pain. Relationship between the type, treatment period, dosage of opioid agents and hormonal abnormalities can be examined by measuring the functional level of the adrenal glands. We hope to improve patient's quality of life by indicating hormone substitution to treat symptoms of adrenal insufficiency.

The Relationship between Opioids Use, Cortisol and DHEAS (마약성 진통제 사용과 Cortisol 및 DHEAS와의 관계)

  • Jung, Ji Hoon;Choi, Youn Seon;Kim, Seon Mee;Lee, June Young;Kim, Eun Hye;Kim, Jung Eun;Kim, E Yeon;Park, Hee Jin;Yoon, Dong Jin
    • Journal of Hospice and Palliative Care
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    • v.18 no.2
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    • pp.105-111
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    • 2015
  • Purpose: Fatigue, energy loss, feeling of helplessness, poor appetite, pain besides general weakness are major symptoms presented to terminally ill cancer patients. These symptoms are similar to those that appeared with adrenal insufficiency. Also, for terminally ill cancer patients who are hospitalized for palliative care, opioid agents are prescribed to control moderate to severe pain. We studied the relationship of opioid agents and adrenal insufficiency. Methods: From November 2013 through June 2014, we monitored the serum level of cortisol and dehydroepiandrosterone sulfate (DHEAS, serum) in 55 cancer patients who were over 18 years old and were treated at a hospice center. We also checked the treatment period and dosage of opioid agents. Results: The DHEAS level, treatment period and dosage of opioid agents did not have significant correlation. Correlation between the serum cortisol level and the opioid agent treatment period was not significant either, but the serum cortisol level was positively correlated with the dosage of opioid agents (P value 0.0322). Conclusion: This study did not identify a novel link between treatment period, dosage of opioid agents and adrenal insufficiency. But, the DHEAS level was mostly below the normal level in patients who were treated with opioid agents.