• Title/Summary/Keyword: 동시치료

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HIV 감염인의 결핵, 예방과 치료 가능하다

  • 김효열
    • RED RIBBON
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    • s.64
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    • pp.16-17
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    • 2005
  • 결핵은 전 세계적으로 가장 흔한 에이즈 관련 기회감염질환의 하나이며, 사하라사막이남 아프리카에서는 에이즈 환자들의 가장 흔한 사망원인이다. 결핵과 HIV는 서로 밀접한 연관성이 있으며, 또한 결핵은 에이즈 환자의 생존에도 많은 영향을 준다. 세계보건기구에 따르면 1997년에 전 세계에서 800만 명의 새로운 결핵환자가 발생하였고, 200만 명이 사망하여 약 $23\%$의 사망률을 보였으며, 이중 결핵과 HIV가 동시에 감염된 경우는 64만 명($8\%$)이었고 이들의 사망률은 $50\%$로 높았다

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Dual reconstruction of both the radial collateral ligament and lateral ulnar collateral ligament at the annular ligament in posterolateral rotatory instability of the elbow: a new technique - A report of 3 cases- (요측측부인대 및 외측척골측부인대의 동시재건술을 이용한 주관절 후외측회전 불안정성의 수술적치료: 새로운 수술 기법 - 증례 3예 보고 -)

  • Ryu, In-Hyeok;Kim, Hyeong-Jin;Jeong, Jae-Ik;Seo, Bo-Geon;Kim, Gyeong-Cheol
    • The Academic Congress of Korean Shoulder and Elbow Society
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    • 2009.03a
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    • pp.189-190
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    • 2009
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자가구동 대장내시경 개발을 위한 생체내 마찰특성 연구

  • 김영태;권은영;성인하;김대은;김병규
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 2004.05a
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    • pp.291-291
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    • 2004
  • 현재 국내에서 꾸준히 증가추세를 보이는 대장관련 질환의 검진과 치료를 위해 대장내시경을 이용한 시술의 빈도가 높아지고 있다. 현재 이용되고 있는 대장내시경은 대부분 구조적으로 굵기는 약 1 cm 이며 길이는 약 1.5 m이다 이러한 내시경은 항문을 통한 삽입이 용이하도록 하기 위해 적당한 유연성과 동시에 축방향의 비교적 큰 Stiffness를 갖고 있으며 최근 개발되고 있는 제품들은 이러한 Stiffness의 조절이 가능하여 삽입이 효과적으로 이루어질 수 있도록 하고 있다.(중략)

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Applications of Next-Generation Sequencing Technology based on Liquid Biopsy for Solid Tumor (고형암에서 액체 생검 기반의 차세대염기서열분석법 응용 기술)

  • Kim, Jin-Hee
    • Proceedings of the Korea Contents Association Conference
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    • 2019.05a
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    • pp.469-470
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    • 2019
  • 차세대염기서열분석법(NGS, Next Generation Sequencing) 기술은 하나의 유전체를 무수히 많은 조각으로 분해하여 각 조각을 동시에 읽어낸 뒤, 전산기술을 이용하여 조합함으로써 방대한 유전체 정보를 빠르게 해독하는 방법이다. 한편, 액체 생검(LB, liquid biopsy)이란 암세포가 깨지면서 생기는 미량의 DNA 조각을 말초혈액 속에서 찾아내 암을 진단하는 기술로 조직 생검(tissue biopsy)에 비해 비침습적이다. 본 논문은 NGS와 LB 기술을 접목했을 때 확진이 가능하고 예후 및 치료경과의 예측이 가능함을 제언하였다.

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Combined Chemotherapy and Radiation Therapy in Limited Disease Small-Cell Lung Cancer (국한성 소세포 폐암에서 항암 화학 및 흉부 방사선치료의 병합요법 적응)

  • Kim Moon Kyung;Ahn Yong Chan;Park Keunchil;Lim Do Hoon;Huh Seung Jae;Kim Dae Yong;Shin Kyung Hwan;Lee Kyu Chan;Kwon O Jung
    • Radiation Oncology Journal
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    • v.17 no.1
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    • pp.9-15
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    • 1999
  • Purpose : This is a retrospective study to evaluate the response rate, acute toxicity, and survival rate of a combined chemotherapy and radiation therapy in limited disease small cell lung cancer, Materials and Methods : Firty-six patients with limited disease small-cell lung cancer who underwent combined chemotherapy and radiation therapy between October 1994 and April 1998 were evaluated. Six cycles of chemotherapy were planned either using a VIP regimen etoposide, ifosfamide, and cis-platin) or a EP regimen (etoposide and cis-platin). Thoracic radiation therapy was planned to deli- ver 44 Gy using 1 OMV X-ray, starting concurrently with chemotherapy. Response was evaluated 4 weeks after the completion of the planned chemotherapy and radiation therapy, and the prophylaetic cranial irradiation was planned only for the patients with complete responses. Acute toxicity was evaluated using the SWOG toxicity criteria, and the overall survival and disease-free survival were calculated using the Kaplan-Meier Method. Results : The median follow-up period was 16 months (range:2 to 41 months). Complete response was achieved En 30 (65$\%$) patients, of which 22 patients received prophylactic cranial irradiations. Acute toxicities over grade III were granulocytopenia in 23 (50$\%$), anemia in 17 (37$\%$), thrombo- cytopenia in nine (20$\%$), alopecia in nine (20$\%$), nausea/vomiting in five (11$\%$), and peripheral neuropathy in one (2$\%$). Chemotherapy was delayed in one patient, and the chemotherapy doses were reduced in 58 (24$\%$) out of the total 246 cycles. No radiation esophagitis over grade 111 was observed, while interruption during radiation therapy for a mean of 8.3 days occurred in 21 patients. The local recurrences were observed in 8 patients and local progressions were in 6 patients, and the distant metastases in 17 patients. Among these, four patients had both the local relapse and the distant metastasis. Brain was the most common metastatic site (10 patients), followed by the liver as the next common site (4 patients). The overall and progression-free survival rates were 79$\%$ and 55$\%$ in 1 year, and 45'/) and 32% in 2 years, respectively, and the median survival was 23 months. Conclusion : Relatively satisfactory local control and suwival rates were achieved after the combined chemotherapy and radiation therapy with mild to moderate acute morbidities in limited disease small cell lung cancer.

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A Case Report on Two Psoriasis Patients with Insomnia (불면증상을 동반한 건선 환자 치험 2례)

  • Lee, Ki Hoon;Yang, Ji Eun;Chang, Gyu Tae
    • The Journal of Korean Medicine
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    • v.36 no.1
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    • pp.86-92
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    • 2015
  • Objectives: The purpose of this study is to present two treatment cases of psoriasis with insomnia. Methods: We administered Guibi-tang medication to the psoriasis patients with insomnia and tested the results by Psoriasis Area and Severity Index(PASI) and Insomnia Severity Index(ISI) as well. Results: After the treatment both the patients showed improvements in PASI and ISI as well. PASI of Patient 1 changed from 15.2 to 1.2 along with the change of ISI from 27 to 2. In case of Patient 2, PASI changed from 14.6 to 1.8 while ISI changed from 21 to 6. Conclusions: The results suggest that Guibi-tang can be an effective treatment for insomnia and psoriasis as well. Further studies will be needed to demonstrate conclusively the effect of Guibi-tang on psoriasis cure.

Simultaneous Heat-Massage Therapy for Migraine Without Aura : A Case Report (무전조성 편두통 환자에서 온열과 마사지 동시 치료의 효과: 증례보고)

  • Lee, Kwang-Jae;Yoon, Yong-Soon
    • Journal of Digital Convergence
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    • v.18 no.8
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    • pp.505-509
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    • 2020
  • A migraine was a headache disorder characterized by recurrent moderate to severe headaches. The diagnosis was based on clinical signs and symptoms. Medication, physical therapy, nerve block, and nerve stimulation could be applied for treatment. This report described a case of severe migraine without aura that lasted several weeks periodically in a 59-year-old woman. Periodic headache had lasted for more than 14 years, and although she took medicines and nerve blocks, severe pain (VAS 7) was persisted. We recommended her to use the thermo-spinal massage device (CGM MB-1401, CERAGEM Inc., Cheonan, South Korea) continuously three times a week applying in semi-automatic mode around the neck for 40 minutes. There was no change in the pain scale in the automatic mode for the first 4 weeks. Subsequently, the semi-automatic mode of the cervical area was treated for 2 weeks to relieve the pain scale, and it was confirmed that the relieved state maintained for 2 months. This case highlighted the importance in considering thermo-spinal massage devices for managing migraine without aura.

Implementation of Non-Invasive Cerebral blood Increasing Platform using PI (혈류지수를 이용한 비침습적 대뇌혈류증가 장치의 구현)

  • Kwon, Seong-tae;Lee, Jean;Kim, Young-kil
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.21 no.9
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    • pp.1761-1770
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    • 2017
  • Treatment for cerebral blood flows is one of the most important treatments for cerebral infarction. There is a concern that the increasing number of cerebral blood flow treatments can cause multiple complications as it is invasive. To compensate for these problems, recently non-invasive cerebral blood flow increases have emerged. However, the current implementation of the non-invasive cerebral blood flow sensor raises the question of speed and accuracy. In this theses, the system aims to minimize the final cortical damage to the cerebrum by implementing a system in a completely different manner to complement the disadvantages of the existing non-invasive cerebral blood flow device. The system measure the PI of the limbs while simultaneously pressing limbs. Blood flow rate is carried out indirectly by increasing blood flow to peer pressure through the limbs in which the PI eips below a certain level. This can be used selectively in patients to increase blood flow.

Dose and Image Evaluations of Imaging for Radiotherapy (방사선치료를 위한 영상장비의 선량 및 영상 평가)

  • Lee, Hyounggun;Yoon, Changyeon;Kim, Tae Jun;Kim, Dongwook;Chung, Weon Kyu;Park, Sung Ho;Lee, Wonho
    • Progress in Medical Physics
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    • v.23 no.4
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    • pp.292-302
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    • 2012
  • The patient dose in advanced radiotherapy techniques is an important issue. These methods should be evaluated to reduce the dose in diagnostic imaging for radiotherapy. Especially, the Computed Tomography in radiotherapy has been used widely; hence the CT was evaluated for dose and image in this study. The evaluations for dose and image were done in equal condition due to compare the dose and image simultaneously. Furthermore, the possibility of dose and image evaluations by using the Monte Carlo simulation MCNPX was confirmed. We made the iterative reconstruction for low dose CT image to elevate image quality with Maximum Likelihood Expectation Maximization; MLEM. The system we developed is expected to be used not only to reduce the patient dose in radiotherapy, also to evaluate the overall factors of image modalities in industrial research.