• Title/Summary/Keyword: 다중치료중심

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IMRT optimization on multiple slice using gradient based algorithm (Gradient based algorithm을 이용한 multiple slice IMRT optimization)

  • Lee, Byung-Yong;Cho, Byung-Chul;Lee, Seok;Jung, Won-Kyun;An, Seung-Do;Choi, Eun-Kyung;Kim, Jong-Hoon;Jang, Hye-Sook
    • Progress in Medical Physics
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    • v.9 no.4
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    • pp.201-206
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    • 1998
  • IMRT optimization method on multiple slice has been developed by using gradient based algorithm. On about 10-30 CT slices including treatment region of a patient, dose optimization has been performed slice by slice to meet the condition that each organ should be exposed below maximum tolerable doses and that the tumor dose within the range of 100$\pm$5 %. Field size was limited to 8$\times$8 cm$^2$ and in this condition, beam divergence was not taken into account to calculate dose distribution. Total dose distribution was calculated by superposing each beamlet whose dose distribution had been precalculated. In order to investigate beam number dependency, dose optimization was performed for one, three, five, seven, and nine coplanar beams and then each optimization index was evaluated. It is found that optimization time was proportional to number of slices to be optimized, and the most efficient plan was obtained from the case of three-to-seven incident beams with respect to calculation time and optimization index. In conclusion, dose optimization of multiple slice was able to be obtained by repeating dose optimization of single slice under condition that the beam size is not too large to ignore beam divergence. And it turns out that result of dose optimization was so sensitive to the position of isocenter that some method to optimize isocenter position is needed to improve it.

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Non-Pharmacological Interventions for Behavioral and Psychological Symptoms of Neurocognitive Disorder (신경인지장애의 정신행동증상에 대한 비약물학적 개입)

  • Hyun Kim;Kang Joon Lee
    • Korean Journal of Psychosomatic Medicine
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    • v.31 no.1
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    • pp.1-9
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    • 2023
  • Patients with neurocognitive disorder show behavioral psychological symptoms such as agitation, aggression, depression, and wandering, as well as cognitive decline, which puts a considerable burden on patients and their families. For the treatment of behavioral psychological symptoms, patient-centered, non-pharmacological treatment should be used as a first line approach. This paper describes non-pharmacological interventions to manage and treat behavioral psychological symptoms in patients with neurocognitive disorder. In order to control behavioral psychological symptoms such as agitation, depression, apathy, insomnia, and wandering, it is important to identify and evaluate factors such as environmental changes and drugs, and then solve such problems. Non-pharmacological interventions include reassurance, encourage, distraction, and environmental change. It is necessary to understand behavior from a patient's point of view and to approach the patient's needs and abilities appropriately. Reminiscence therapy, music therapy, aroma therapy, multisensory stimulation therapy, exercise therapy, light therapy, massage therapy, cognitive intervention therapy, and pet therapy are used as non-pharmacological interventions, and these approaches are known to improve symptoms such as depression, apathy, agitation, aggression, anxiety, wandering, and insomnia. However, the quality of the evidence base for non-pharmacological approaches is generally lower than for pharmacological treatments. Therefore, more extensive and accurate effectiveness verification studies are needed in the future.

Accuracy Evaluation of Three-Dimensional Multimodal Image Registration Using a Brain Phantom (뇌팬톰을 이용한 삼차원 다중영상정합의 정확성 평가)

  • 진호상;송주영;주라형;정수교;최보영;이형구;서태석
    • Journal of Biomedical Engineering Research
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    • v.25 no.1
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    • pp.33-41
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    • 2004
  • Accuracy of registration between images acquired from various medical image modalities is one of the critical issues in radiation treatment planing. In this study, a method of accuracy evaluation of image registration using a homemade brain phantom was investigated. Chamfer matching of CT-MR and CT-SPECT imaging was applied for the multimodal image registration. The accuracy of image correlation was evaluated by comparing the center points of the inserted targets of the phantom. The three dimensional root-mean-square translation deviations of the CT-MR and CT-SPECT registration were 2.1${\pm}$0.8 mm and 2.8${\pm}$1.4 mm, respectively. The rotational errors were < 2$^{\circ}$ for the three orthogonal axes. These errors were within a reasonable margin compared with the previous phantom studies. A visual inspection of the superimposed CT-MR and CT- SPECT images also showed good matching results.

Development of Problem-based learning module for Bioterrorism (생물테러재난안전교육을 위한 문제중심학습개발)

  • Kim, Jee-Hee;Moon, Tae-Young;Park, Jeong-Hyun
    • Proceedings of the KAIS Fall Conference
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    • 2009.12a
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    • pp.774-777
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    • 2009
  • 2001년 9 11 테러 이후 미국에서 탄저균을 이용한 생물테러가 발생한 이래 미국을 비롯한 여러 나라에서는 생물무기 및 생물테러에 대한 대응방안들이 준비되고 있다. 따라서 이런 대응방안과 더불어 생물무기를 쓰는 테러리스트의 행동과 위협에 대비를 할 필요가 있다. 생물테러 전염병은 치명률이 높고, 인간 상호간에 전염이 용이하며 치료하기가 어려우므로, 인명의 손실을 최소화하기 위해서는 보건의료기관 등에서 근무하는 보건의료인이 생물테러로 의심되는 병원체 및 전염병을 조기에 인지하는 것이 가장 중요하다. 따라서 보건분야 전문가들은 환자나 일반 대중, 그리고 다른 보건전문가들에게 생물무기와 생물테러에 의해 퍼질 가능성이 있는 질병들에 대해 신중하게 대응할 수 있는 방법들을 교육해야 한다. 질병이 발생했을 때 보건전문가들은 조사에 착수할 역학자들과 협조를 해야 하고, 임상 또는 연구소에 일하는 보건전문가들은 생물무기로 사용될 수 있는 병원체나 생물무기를 생산하는데 사용되는 시설에 접근하는 것을 제한하도록 도울 수 있다. 2005년 질병관리본부 생물테러대응팀에서는 의료인, 다중시설이용 근무자, 보건요원을 대상으로 생물테러 인식도를 조사한 바 있다. 조사결과, 의료인에 대한 생물테러 교육 및 교육훈련의 필요성에 대해 94.2%가 필요하다고 응답하였다. 이런 자료를 바탕으로 하여 국내에서도 생물테러교육의 필요성이 대두되기 시작하였다. 본 연구는 미국, 영국에서 진행되고 있는 생물테러 관련 교육에 대한 관련 자료와 사례를 문헌 분석을 통해 우리나라에 맞는 생물테러 교육에 대한 방향을 제시하고 문제중심학습모듈을 개발하고자 하는데 그 목적이 있다.

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Analysis of cognitive factors affecting stroke patient's activity of daily living performance -Using the computerized neurocognitive function test- (뇌졸중 환자의 일상 활동 수행에 영향을 미치는 인지요인 분석 -전산화 신경인지기능검사 중심으로-)

  • Kim, Ji-Youn
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.12 no.12
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    • pp.5715-5721
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    • 2011
  • This research analyzed the cognitive factors affecting stroke patient's activity of daily living performance and suggests the approaches which can contribute to the effective activity of daily living performance in the rehabilitation treatment of stroke patients. In this study, Seoul Computerized NeuroCognitive Function Test (SCNT) and MBI have been performed for 21 patients under extensive rehabilitation treatments, hospitalized in the rehabilitation clinic of A hospital after being diagnosed as a stroke caused by cerebrovascular disorders. To assess the effectiveness of the cognitive factors which affect the stroke patient's activity of daily living performance, activity of daily living performance values were set as dependent variables and 10 cognitive factors were included in the model to carry out analysis of the multiple regression analysis. The results show that stroke patient's activity of daily living performance have statistically significant correlations with divided attention, motor control and selectivir attention. In addition, cognitive factors explained 69.8% of the stroke patient's activity of daily living performance. Consequently, if divided attention and motor control are considered as a focal point of training in the rehabilitation treatment of stroke patients, we can effectively promote the improvement of the activity of daily living performanceroutine activities.

Time Series Analysis on Outcomes of Tuberculosis Control and Prevention Program between Small Areas in Korea - with Patient Registry Data of 234 City.County.District Public Health Centers - (소규모 지역간 결핵관리사업 성과에 대한 시계열분석 - 전국 234개 시.군.구 보건소의 환자등록자료를 중심으로 -)

  • Kim, Chun-Bae;Choe, Heon;Shin, Kye-Chul;Park, Jong-Ku;Ham, Soo-Keun;Kim, Eun-Mi
    • Tuberculosis and Respiratory Diseases
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    • v.48 no.6
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    • pp.837-852
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    • 2000
  • Backgrounds : Today, tuberculosis cannot only be cured medically, but also controlled by public health. Despite the overall worldwide decline in tuberculosis, the disease continues to be a significant problem among developing countries and in the slums of large cities in some industrialized countries. Particularly, this communicable disease has come into the public health spotlight because of its resurgence in the 1990's. our country has been operating the Korean National Tuberculosis Control Program since 1962, focusing around public health centers. Therefore, this study aims to compare the effectiveness of tuberculosis control activities, one of the major public health activities in Korea, by producing indexes, such as the yearly registration rate per 100,000 population and treatment compliance of tuberculosis on in small areas (communities). Methods : This work was accomplished by constructing a time-series analytic model using data from "1980~2000: the Yearly Statistical Report" with patient registry data of 234 City. County. District public health centers and by identifying the factors influencing the tuberculosis indexes. Results : The trends of pulmonary tuberculosis positive point prevalence and pulmonary tuberculosis negative point prevalence on X-ray screening have declined steadily, beginning in 1981 and continuing to 1998 by region (city, county, district). Although the tuberculosis mortality rate steadily shows a declining trend by year and region, but Korea still ranks first among 29 OECD countries in 1998, with a tuberculosis mortality rate of 7.1 per 100,000 persons, according to the time-series analysis for fatal diseases. Conclusion : The results of the study will form the fundamental basis of future regional health care planning and the Korean Tuberculosis Surveillance System on 2000. Since the implementation of local autonomy through the Local Health Act of 1995, it has now become vita1 for each city, county, district public health centers to determine its own priorities for relevant health care management, including budget allocation and program goals.

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Influence of Work Preference and Self-efficacy on Creative Leadership of Nursing Students (작업선호도, 자아효능감이 간호대학생의 창의적 리더십에 미치는 영향)

  • Choi, Mi-Jung;Heo, Myoung
    • Journal of Korea Entertainment Industry Association
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    • v.13 no.2
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    • pp.219-229
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    • 2019
  • The purpose of this study was to investigate the effects of internal and external motivation and self -efficacy on the development of creative leadership as a collective of self-leadership, servant leadership and problem-solving leadership. For the study, Amabile's work preference, self-efficacy test, and creative leadership test were conducted in 195 nursing students at G city. Correlation analysis and regression analysis were conducted through SPSS24.0 program. First, creative leadership showed a significant positive correlation with internal motivation and self-efficacy. Second, multiple regression analysis was conducted focusing on factors showing significant differences in correlation. As a result, self-efficacy and intrinsic motivation were the factors influencing creative leadership. There was 60% explanatory force. It is necessary to improve self-efficacy and intrinsic motivation in order to improve creative leadership.

Three Dimensional Target Volume Reconstruction from Multiple Projection Images (다중투사영상을 이용한 표적체적의 3차원 재구성)

  • 정광호;진호상;이형구;최보영;서태석
    • Progress in Medical Physics
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    • v.14 no.3
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    • pp.167-174
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    • 2003
  • In the radiation treatment planning (RTP) process, especially for stereotactic radiosurgery (SRS), knowing the exact volume and shape and the precise position of a lesion is very important. Sometimes X-ray projection images, such as angiograms, become the best choice for lesion identification. However, while the exact target position can be acquired by bi-projection images, 3D target reconstruction from bi-projection images is considered to be impossible. The aim of this study was to reconstruct the 3D target volume from multiple projection images. It was assumed that we knew the exact target position in advance, and all processes were performed in Target Coordinates, where the origin was the center of the target. We used six projections: two projections were used to make a Reconstruction Box and four projections were for image acquisition. The Reconstruction Box was made up of voxels of 3D matrices. Projection images were transformed into 3D in this virtual box using a geometric back-projection method. The resolution and the accuracy of the reconstructed target volume were dependent on the target size. An algorithm was applied to an ellipsoid model and a horseshoe-shaped model. Projection images were created geometrically using C program language, and reconstruction was also performed using C program language and Matlab ver. 6(The Mathwork Inc., USA). For the ellipsoid model, the reconstructed volume was slightly overestimated, but the target shape and position proved to be correct. For the horseshoe-shaped model, reconstructed volume was somewhat different from the original target model, but there was a considerable improvement in determining the target volume.

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A Study on Scenario to establish Coastal Inundation Prediction Map due to Storm Surge (폭풍해일에 의한 해안침수예상도 작성 시나리오 연구)

  • Moon, Seung-Rok;Kang, Tae-Soon;Nam, Soo-Yong;Hwang, Joon
    • Journal of Korean Society of Coastal and Ocean Engineers
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    • v.19 no.5
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    • pp.492-501
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    • 2007
  • Coastal disasters have become one of the most important issues in every coastal country. In Korea, coastal disasters such as storm surge, sea level rise and extreme weather have placed many coastal regions in danger of being exposed or damaged during subsequent storms and gradual shoreline retreat. A storm surge is an onshore gush of water associated with a tow pressure weather system, typically in typhoon season. However, it is very difficult to predict storm surge height and inundation due to the irregularity of the course and intensity of a typhoon. To provide a new scheme of typhoon damage prediction model, the scenario which changes the central pressure, the maximum wind radius, the track and the proceeding speed by corresponding previous typhoon database, was composed. The virtual typhoon scenario database was constructed with individual scenario simulation and evaluation, in which it extracted the result from the scenario database of information of the hereafter typhoon and information due to climate change. This virtual typhoon scenario database will apply damage prediction information about a typhoon. This study performed construction and analysis of the simulation system with the storm surge/coastal inundation model at Masan coastal areas, and applied method for predicting using the scenario of the storm surge.

The Effect of Internalized Shame and Self-Control on Interpersonal Relationships in Stroke Patients (내면화된 수치심과 자기통제력이 뇌졸중 환자의 대인관계에 미치는 영향)

  • Hwang, Jung-Ha;Lim, Jae-Ho
    • The Journal of Korean society of community based occupational therapy
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    • v.10 no.3
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    • pp.63-74
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    • 2020
  • Objective : The purpose of this study is to investigate the influence of internal shame and self-control on interpersonal relationships in stroke patients, and to provide evidence and information necessary for clinical trials by analyzing the relationship. Methods : For this study, 150 stroke patients receiving occupational therapy services at institutions where occupational therapists work in Jeollanam-do and Chungnam regions were targeted through email and mail from March 1, 2019 to April 30, 2019. The questionnaire was conducted using general characteristics, Relationship Change Scales(RCS), Self-Control Scales(SCS), and Internalized Shame Scale(ISS) questionnaire. Descriptive statistical analysis was performed for the general characteristics of the study subjects, and t-test and one-way batch variance analysis (ANOVA) were used to compare interpersonal relationships according to general characteristics. The relationship between internalized shame, self-control, and interpersonal competence was analyzed by Pearson's correlation coefficient, and multiple regression analysis was performed to determine the factors affecting interpersonal relationships of stroke patients. Results : As a result of comparing interpersonal competence according to general characteristics, significant differences were found in terms of age and education level. Interpersonal relationships and internalized shame, internalized shame and self-control showed a negative correlation, and self-control and interpersonal relationships had a positive correlation, but self-control was the sub-factors of interpersonal relationships such as openness, sensitivity, intimacy, It was not statistically significant with the communication item. In addition, the items of inadequacy (β =-0.32) and adventure seeking (β =-0.23), which are sub-areas of internalized shame, affect the negative direction, and physical activity (β =0.22), which is the sub-area of self-control and the self-centered (β =0.24) item was found to have an effect on the positive direction. Conclusion : Therefore, additional research is needed that can operate a rehabilitation treatment program that applies various psychological factors for the formation of interpersonal relationships among stroke patients.