• Journal of Gastric Cancer
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• v.5 no.2
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• pp.79-88
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• 2005

Quality assurance may be defined as the complete set of systemic actions that is required to achieve a better treatment result by standardizing treatment and by using various audit programs. In general, application of a quality assurance program in surgery is considered to be more difficult than it is in chemotherapy or radiotherapy. However, recently, the importance of quality assurance in the surgical field has been emphasized in clinical trials comparing different surgical procedures and evaluating the role of postoperative adjuvant therapy. In the case of gastric cancer surgery, excellent quality assurance programs have rarely been applied in most large prospective clinical trials. Although the quality assurance in Dutch trial was conducted very systemically and strictly, the situation is quite different from ours. On the other hand, several quality assurance programs in Japanese trials comparing D2 and D2 plus para-arotic lymph node dissection seem to be applicable to Korean clinical trials. Several factors, including selection of appropriate surgeons based on personal experience and annual number of operations, standardization of surgical procedures by education and consensus, development of a unified database program, application of standardized perioperative management, and standardization of pathologic examination, are required to guarantee a successful multi-institutional prospective clinical trial. In contrast, one needs to realize that protocols that are too strict and sophisticated can make the enrollment of patients and surgeons more difficult and can promote protocol violation during the clinical trials. (J Korean Gastric Cancer Assoc 2005;5:79-88)

• Proceedings of the Korea Water Resources Association Conference
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• 2022.05a
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• pp.374-374
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• 2022

상수도 시스템은 물을 수용가에 깨끗하고 충분하게 공급하는 사회기반시설 중 하나이다. 최근 상수도관로 노후화로 인하여 발생하는 누수, 적수, 단수 등의 피해를 방지하기 위하여 상수도관로 점검 및 진단을 수행하고 관 상태를 평가하여 해당 요소에 대한 보수 및 보강을 시행하고 있다. 하지만 기존의 정비사업은 관 노후도를 고려한 보강계획을 수립하여 효과적인 상수도 시스템 정비를 위하여 상수도관로에 영향을 미치는 수리 및 수질 평가를 통합적으로 고려한 보강 우선순위 결정이 필요하다. 따라서 본 연구에서는 상수도 시스템의 구조적, 비구조적 평가 인자를 동시에 고려한 시스템 보강 우선순위 선정을 위한 통합평가 기술을 제안하였다. 보강 우선순위 선정을 위하여 실제 상수도관로가 설치된 지역을 대상으로 상수도관로의 수리. 수질, 관 상태 등의 구조적 인자와 중요시설, 단수 시 피해인구 등의 비구조적 인자를 고려한 통합평가를 수행하였다. 구조적 인자 중 수리 및 수질 인자는 수리해석기법을 이용하여 기준치 통과 여부에 따라 평가하였으며 상수도관로의 관 상태는 관로의 제원, 매설 깊이, 노후도 등의 기준으로 평가하였다. 이러한 평가를 바탕으로 우선순위 선정을 위해 다기준의사결정법을 이용하여 상수도관로의 보강 우선순위를 선정하였다. 본 통합평가는 상수도관로의 구조적, 비구조적 위험도를 정량적으로 인지할 수 있을 뿐만 아니라 비구조적 인자를 고려하여 기존의 평가방법보다 더 신뢰할 수 있는 결과를 제공한다.

• Journal of Bio-Environment Control
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• v.22 no.2
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• pp.123-130
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• 2013

$CO_2$ enrichment systems have been recently used to shorten the growth period of plants and the improvement of harvest and its quality. To accomplish these goals, manifold should be designed to supply the same amount of $CO_2$. In this study, CFD approach has been used to understand the effects of geometric parameters, such as tube and hole diameters. An optimized geometry has been derived through pipe and tube part, respectively. As a result, the deviation of flow rate less than 0.1 g/s was expected at all holes of the $CO_2$ enrichment system.

• Proceedings of the Korean Society of Applied Pharmacology
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• 1993.04a
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• pp.94-94
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• 1993

Angiotensin 전환효소 억제제를 재료로하여 다기관 협동을 통한 시판 후 조사방법론을 개발하고, 아울러 Angiotensin 전환효소 억제제 투여시 나타나는 기침의 발생율과 이와 관련된 요인을 밝히고자 시판 후 조사를 시도하였다. 방법: 1992년 2월부터 1992년 10월까지 11개 병원 가정의학과를 방문하여 Angiotensin 전환효소 억제제를 투여한 고혈압 환자 348명을 연구대상으로 하였다. 이중 남자가 147명, 여자가 201명이었으며, 연령별로는 39세이하 38명, 40-54세 156명, 55세 이상이 154명이었다. 최초 약물투여 후 2, 4, 8, 12주에 추적 관찰하였으며, 기침의 발생율은 PC-SAS 6.04를 이용하여 Kaplan-Meier 방법과 Log-Rank 방법으로 분석하였다.

• The Korean Journal of Applied Statistics
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• v.28 no.6
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• pp.1209-1216
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• 2015

Competing-risks events are often observed in a clustered clinical study such as a multi-center clinical trial. We propose a joint modelling approach via a shared frailty term for competing risks survival data from a cluster. For the inference we use the hierarchical likelihood (or h-likelihood), which avoids an intractable integration. We derive the corresponding h-likelihood procedure. The proposed method is illustrated via the analysis of a practical data set.

• KIPS Transactions on Computer and Communication Systems
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• v.9 no.10
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• pp.239-246
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• 2020

In the medical field where artificial intelligence technology is introduced, research related to clinical decision support system(CDSS) in relation to diagnosis and prediction is actively being conducted. In particular, medical imaging-based disease diagnosis area applied AI technologies at various products. However, medical imaging data consists of inconsistent data, and it is a reality that it takes considerable time to prepare and use it for research. This paper describes a one-stop AI learning platform for converting to medical image standard R_CDM(Radiology Common Data Model) and supporting AI algorithm development research based on the dataset. To this, the focus is on linking with the existing CDM(common data model) and model the system, including the schema of the medical imaging standard model and report information for multi-center research based on DICOM(Digital Imaging and Communications in Medicine) tag information. And also, we show the execution results based on generated datasets through the AI learning platform. As a proposed platform, it is expected to be used for various image-based artificial intelligence researches.

• Transactions of the Korean Society of Automotive Engineers
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• v.5 no.6
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• pp.175-182
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• 1997

The purpose of this study is to investigate the effects of intake manifold shapes to improve the engine performance in a 3-cylinder LPG engine with a closed loop fuel supply system. To know the flow resistance of intake manifolds with shape, the intake negative pressure of each runner in intake manifolds were measured by using the digital pressure meter at each driving condition. And, the engine torque and power have been measured with an engine dynamometer while adjusting the optimal fuel consumption ratio with a solenoid driver. As 속 results form this experiment, the torque characteris- tics were more improved with the plenum chamber(B type intake manifold) than with the banana type(A type intake manifold). The torque characteristics were improved at mid-engine speed(rpm) range as the inner diameter of the intake manifold became smaller. And also the optimum volume among the examined plenum chamber volume was 0.74 times(590cc) the displacement of the test engine.

• Sleep Medicine and Psychophysiology
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• v.23 no.2
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• pp.84-92
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• 2016

Objectives: The purpose of this study was to estimate the safety and efficacy of a mandibular advancement device (MAD), 'Bioguard,' for the treatment of obstructive sleep apnea (OSA). Methods: In this 5-week prospective, multi-center, single group, and non-inferiority trial, patients who chose 'Bioguard' as their treatment option were evaluated using both questionnaires (Pittsburgh Sleep Quality Index (PSQI), Epworth sleepiness scale (ESS)) and polysomonography (PSG) (apnea hypopnea index (AHI), oxygen saturation). All patient data, including clinical records, PSG studies (both pre- and post-treatment), and adverse events (AEs), were reviewed and analyzed. Results: Results were obtained for 59 of 62 patients (95.16%). No significant difference in success rate was found between the MAD treatment and surgical treatment (95% CI). AHI, PSQI, ESS and oxygen saturation demonstrated significant improvement (p < 0.001) after MAD treatment, and 39 of 62 patients (62.9%) reported 85 AEs. 79 of the 85 AEs (91.8%) were mild cases, and there were no severe AEs related to the MAD treatment. Conclusion: The MAD 'Bioguard' should be considered as an alternative treatment option for OSA patients.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• 2012.06a
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• pp.146-147
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• 2012

급변하는 항만의 교통특성과 이용자들의 정보서비스 욕구에 발맞추어 해상교통관제 운영기법이 변화하고 있으며 차세대 다기능 해상교통정보시스템과 같은 새로운 기술이 개발되는 등 해상교통물류체제의 혁신이 이루어지고 있다. 이에 따라 세계 각국은 해상교통관제구역을 항행하는 선박의 질서유지 및 안전사고 예방과 사고 발생 시 신속한 대응조치를 위하여 해상교통관제사의 인력양성 및 인력관리에 많은 노력을 기울이고 있다. 국내에서도 선진해양교통행정을 위하여 분산된 해상교통관제 기능일 일원화 되어감에 따라 새로운 해상교통관리 체제의 효율적인 운영을 위하여 해상교통관제사들의 지속적인 훈련의 필요성이 대두되고 있지만 교육제도의 인지, 여건, 장비보급의 부족, 다양한 상황에 대한 교육시나리오의 부족으로 인하여 시뮬레이터를 이용한 교육이 효율적으로 이루어지지 못하는 문제점이 발생하고 있다. 본 연구에서는 해상교통관제사들의 교육을 위한 국내 외 규정을 분석하고 교육현황 및 해상교통관제사들의 요구사항을 파악하여 해상교통관제시뮬레이터를 이용한 교육의 개선방안을 제시하고자 한다.

• 대한예방의학회:학술대회논문집
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• 2005.10a
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• pp.463-463
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• 2005