• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.8 no.1
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• pp.113-122
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• 1997

The purpose of this study was to examine brain structural abnormalities in autistic children. Magnetic resonance imaging(MRI) findings in 22 male children with a DSM-Ⅲ-R diagnosis of autistic disorder and 17 non-autistic male control children were investigated. The ratio measures by lineometry was used to examine the cerebrum, midbrain, cerebellum, brain stem and ventricular system. The left to right ratio of the lateral ventricle was larger in autistic children than in controls. The pons was significantly larger in autistic children than in controls, and the cerebellum was smaller in autistic children. There were no significant differences between autistic children and controls in the symmetricity of the fontral lobe, parietal lobe, occipital lobe and temporal lobe, and in the size of the midbrain and 4th ventricle. These findings suggest that autistic disorder may be related to structural impairment of the brain.

• Journal of Acupuncture Research
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• v.20 no.5
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• pp.244-251
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• 2003

Objective: The main symptoms of the Wallenberg's syndrome are ataxia of gait, clumsiness of ipsilateral limbs, nausea and vomiting, vertigo, visual disturbance such as difficulty in focusing blurred vision diplopia, numbness, dysphagia, hoarseness, hiccup, nystagmus, Homer's syndrome. The purpose of this paper is to report the patient with the Wallenberg's syndrome who was improved by oriental medical treatment. Methods: In terms of exuberance of Yang(vital function) of the liver and stagnation of the liver Ki(energy), we let the patient take Chunghunhwadam-Tang, Hwangryeonhaedok-Tang and Dangkwihwalhyeol-Tang, at the same time, treated with acupuncture, Sa-Am and Dong-Si acupuncture therapy twice a day. Results: We could know that symptoms of the Wallenberg's Syndrome were improved after observing left sensory paralysis was almost recovered, hiccup was completely healed and vertigo was reduced to 1/10. Conclusions: We confirmed that oriental drugs and acupuncture by differentiation of syndromes make the patient with the Wallenberg's Syndrome reduce and improve symptoms he has.

• The Journal of Internal Korean Medicine
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• v.26 no.4
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• pp.881-888
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• 2005

Pontine infarction presents variable neurologic deficits because the pons is a very complicated organ with cranial nerve nuclei and several fiber tracts. A 65 year-old women with dizzness, ataxia and diplopia because of Pontine infarction was admitted at Wonkwang University Jeonju Oriental Medicine Hospital. She was treated with the herbal medicine Joganiknoe-tang(助肝益腦湯) and with acupunture. Improvement in these symptoms was observed, so the specifics of the process in which the patient was treated are here described. Results suggest that Joganiknoe-tang(助肝益腦湯) is an effective treatment for symptoms of pontine infarction.

• Journal of Acupuncture Research
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• v.23 no.3
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• pp.241-247
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• 2006

Objectives : This study is to report one case of the patient who has exotropia caused by unilateral internuclear ophthalmoplegia due to pontine infarction, which is a rare disease so there has few research about the effect of acupuncture therapy on it, treated with the SAAM(舍巖) Acupuncture Sojangjeonggyeok(小湯正洛) Methods & Results : In the point of differentiation of Syndrome, these subjects were diagnosed as deficiency of Yin and blood(陰血不足). We treated her with SAAM Acupuncture Sojangjeonggyeok(小湯正洛), herb medication(淸肝湯, 六味地黃湯), and the symptoms were resolved clearly by above treatment during about a week. Conclusion : This case shows proper oriental medical treatment based on the exact differentiation of symptoms has good effect on this disease as one of conservative therapies.

• Journal of Acupuncture Research
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• v.33 no.4
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• pp.191-201
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• 2016

Objectives : The purpose of this study is to report the clinical effect of Korean and Western medical treatment on a hemiplegic inpatient with central pontine myelinolysis(CPM). Methods : A patient who was diagnosed with central pontine myelinolysis(CPM) was treated with acupuncture, herbal medicine, Korean physical therapy, along with receiving continuous Western medication and rehabilitation treatment. The patient was evaluated through Manual Muscle Testing(MMT), measurement of grip strength, dysarthria, and dysuresia. The Korean and Western medical treatment was conducted for 4 weeks. Results : After the 4 weeks of Korean and Western medical treatment, MMT grade improved from 2 to 4 and grip strength improved from 6 to 13. Dysarthria and dysuresia also improved. Conclusion : According to these results, this report suggests that Korean and Western medical treatment could be effective in the treatment of central pontine myelinolysis(CPM) patients.

• The Journal of Internal Korean Medicine
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• v.25 no.4
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• pp.200-206
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• 2004

Anterior inferior cerebellar artery(AICA) is a branch of the basilar artery which supplies the bloods for ventrolateral cerebellum and the lateral tegmentum of the lower two-thirds of pons. AICA occlusion can cause such symptoms as acute-onset unilateral deafness, vertigo, facial weakness and ataxia. A case of sudden hearing loss, facial palsy and vertigo caused by AICA territory infarction recently presented itself. Korean Oriental and Western medical therapy were applied in combination. Facial palsy and vertigo improved, but hearing loss did not improve. This case is reported with a brief overview of related literatures.

• Sleep Medicine and Psychophysiology
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• v.2 no.2
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• pp.133-137
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• 1995

The author reviews current knowledge about what REM sleep is and where and how it is generated. REM sleep is the state in which our most vivid dreams occur. REM sleep is identified by the simultaneous presence of a desynchronized cortical EEG, an absence of activity in the antigravity muscles(atonia), and periodic bursts of rapid eye movements. Another characteristic phenomena of REM sleep are the highly synchronized hippocampal EEG of theta frequency and the ponto-geniculo-occipital(PGO) spike. All these phenomena can be explained in terms of changes in neuronal activity. Transection studies have determined that the pons is sufficient for generating REM sleep. Lesion studies have identified a small region in the lateral pontine tegmentum corresponding to lateral portions of the nucleus reticularis pontis oralis(RPO) and the region immediately ventral to the locus coeruleus, which is required for REM sleep. Unit recording studies have found a population of cells within this region that is selectively active in REM sleep. Cholinergic neurons of the giant cell field of pontine tegmentum(ETG), which is 'REM a sleep-on cells', has shown to be critically involved in the generation of REM sleep. Noradrenergic neurons of the locus coeruleus and serotonergic neurons of the dorsal raphe, which are called 'REM sleep-off cells', appear to act in a reciprocal manner to the cholinergic neurons. It is proposed that the periodic cessations of discharge of 'REM sleep-off cells' during REM sleep might be significant for the prevention of the desensitization of receptors of these neurons.

• The Journal of Internal Korean Medicine
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• v.37 no.2
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• pp.298-304
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• 2016

Objective: : This clinical study reports on the effect of Sunghyangjungki-san-gami and Banhabaeckchulchunma-tang-gami on hemiplegia, dizziness, and hiccupping caused by pontine infarction.Methods: This study was performed on one patient with hemiplegia, dizziness, and hiccupping caused by pontine infarction. The patient was treated by Sunghyangjungki-san-gami and Banhabaeckchulchunma-tang-gami from 6 January to 2 March 2015. The National Institutes of Health stroke scale (NIHSS), motor grade, and numerical rating scale (NRS) were used to assess the effectiveness of this treatment.Results: After treatment, the patient’s discomfort decreased significantly, and NIHSS, motor grade, and NRS scores were all improved.Conclusion: This clinical study suggests that traditional Korean medicine may be effective in treating hemiplegia, dizziness, and hiccupping caused by pontine infarction.

• Journal of Biomedical Engineering Research
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• v.19 no.6
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• pp.603-609
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• 1998

To anlyze the diffuse axonal injury of the human brain, 3-D finite element models of the adult, two and three years child were developed. Triangular type acceleration which had its maximum value 200g was applied to investigate the effects of acceleration direction and duration time. The pattern of high shear stress generated at the brain stem, pones and midbrain was similar to the pattern of DAI seen in the clinical observation, especially high maximum shear stress was detected in the brain stem of the six year old child model under flexional acceleration. As the duration of acceleration increased generated pressure and maximum shear stress also increased. For the children's model relatively small pressure was generated regardless of the acceleration direction and continued much longer compared with adult's model. From this analysis maximum shear stress was revealed more proper indicator to predict DAI compared to HIC in case of angular acceleration loading.

• The Journal of Internal Korean Medicine
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• v.25 no.3
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• pp.640-647
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• 2004

Pregnancy related stroke is significant because it has dire impact on both mother and the fetus. Pregnant or puerperal women are reported to have about 13-fold more risk of stroke compared to non-pregnant women. Pregnancy-related stroke must be differentiated from stroke in elderly patients, because it is different in pathophysiological etiologies and recurrence rates and also diagnostic and therapeutic methods may affect the fetal health status. Because the VI cranial nerve manages lateral rectus muscles, it' s palsy causes sudden onset of double vision. The eyes turn medially. In this article, one case of paralytic strabismus resulting from pontine hematoma during puerperium is reported. It was treated with herb medicine and acupuncture. Symptoms improved. This case is submitted with a brief overview of related lit.