• Journal of Cadastre & Land InformatiX
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• v.48 no.2
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• pp.185-195
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• 2018

In the Seoul Metropolitan City, the PM(pariculate matter) application used by the citizens provides the PM concentration of the nearest monitoring stations located on the PM monitoring stations. Currently, the selecting method of the PM monitoring network considered by the Ministry of Environment is based on considering the monitoring station distribution and population density only. In this study, we analyzed the distance between PM monitoring station and the administrative center point in addition to the above considerations. The number of test sites was verified and the range of coverage of each monitoring stations was indicated by using the Voronoi algorithm and hexagon grid. The spatial position problem of the PM monitoring station was suggested by spatial data analysis. The variables of spatial data analysis are single-family houses, apartments, $1^{st}$ class neighborhood, $2^{nd}$ class neighborhood, garbage disposal plant, hazardous material disposal facility, factory, and the density map. The analysis result of the selection criterion considering the additional variables for new PM monitoring stations was presented, in addition to the selection criteria provided by the Ministry of Environment.

• Journal of Nutrition and Health
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• v.52 no.6
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• pp.529-539
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• 2019

Purpose: Sprouts of evening primrose (Oenothera laciniata, OL) were reported to have high contents of flavonoids and potent antioxidant activity. This study examined the antioxidant and antiobesity activities of OL sprouts to determine if they could be a natural health-beneficial resource preventing obesity and oxidative stress. Methods: OL sprouts were extracted with 50% ethanol, evaporated, and lyophilized (OLE). The in vitro antioxidant activity of OLE was examined using four different tests. The antiobesity activity and in vivo antioxidant activity from OLE consumption were examined using high fat diet-induced obese (DIO) C57BL/6 mice. Results: The IC₅₀ for the 2,2-diphenyl-1-picryl-hydrazyl (DPPH) radical scavenging and superoxide dismutase (SOD)-like activities of OLE were 26.2 ㎍/mL and 327.6 ㎍/mL, respectively. OLE exhibited the ferric reducing antioxidant power (FRAP) activity of 56.7 ㎍ ascorbic acid eq./mL at 100 ㎍/mL, and an increased glutathione level by 65.1% at 200 ㎍/mL compared to the control in the hUC-MSC stem cells. In an animal study, oral treatment with 50 mg or 100 mg of OLE/kg body weight for 14 weeks reduced the body weight gain, visceral fat content, fat cell size, blood leptin, and triglyceride levels, as well as the atherogenic index compared to the high fat diet control group (HFC) (p < 0.05). The blood malondialdehyde (MDA) level and the catalase and SOD-1 activities in adipose tissue were reduced significantly by the OLE treatment compared to HFC as well (p < 0.05). In epididymal adipose tissue, the OLE treatment reduced the mRNA expression of leptin, PPAR-γ and FAS significantly (p < 0.05) compared to HFC while it increased adiponectin expression (p < 0.05). Conclusion: OLE consumption has potent antioxidant and antiobesity activities via the suppression of oxidative stress and lipogenesis in DIO mice. Therefore, OLE could be a good candidate as a natural resource to develop functional food products that prevent obesity and oxidative stress.

• Proceedings of the KIEE Conference
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• 2011.07a
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• pp.1690-1691
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• 2011

본 논문에서는 H1N1 인플루엔자 A 바이러스(influenza A H1N1 virus) 검출을 위한 산화아연 나노구조(zinc oxide nano structure) 기반의 전기화학적 면역센서를 제작하고 그 특성을 분석하였다. H1N1 인플루엔자 A 바이러스는 빠른 전파 속도 때문에 정확하고 빠른 검출이 필요하다. 먼저, 2 $mm^2$의 표면적을 갖는 패턴된 금 전극 위에 열수방식(hydrothermal method)으로 성장시킨 산화아연 나노구조가 선택적으로 형성되도록 리프트-오프(lift-off) 방법을 사용하였다. 0.01 M phosphate buffered saline(pH 7.4)에서 2 ${\mu}g$/mL 농도의 1차 항체를 정전기력에 의해 산화아연 나노구조에 고정화한 후, 10 pg/mL ~ 5ng/mL 농도의 H1N1 항원을 적용하여 포획 항체에 결합시키고 HRP(horseradish peroxidase) 효소가 결합된 검출 항체를 항원에 결합시키는 샌드위치 ELISA법을 이용하였다. HRP와 반응하는 TMB(3,3', 5,5'-tetramethylbenzidine)와 과산화수소가 포함된 acetate buffered 용액(pH 5)을 전해질로 사용하고 순환전압전류 측정법(cyclic voltammetry)으로 센서의 특성을 분석하였다. 측정된 순환전압전류그래프(cyclic voltammogram)에서 H1N1 항원 농도 10 pg/mL ~ 5 ng/mL의 응답 전류는 276.47 ${\pm}$ 21.72 nA (평균 ${\pm}$ 표준편차, n=4) ~ 478.89 ${\pm}$ 6.21 nA로 측정되었고, logarithmic하게 증가하는 응답 전류 특성을 보였다.

• Journal of Animal Environmental Science
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• v.13 no.3
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• pp.187-194
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• 2007

Six pig farms were surveyed to measure the odor concentrations and characteristics of ammonia and sulfide corollary compounds in piggery. They were depended on the scale of piggery, weather conditions such as temperature, humidity, wind speed and direction, scales and types of pig breeding, and manure treatment methods. The highest ammonia concentrations in piggery were measured during the winter, since the tight sealed insulation in piggery made less amount of generated ammonia discharged from piggery. The objective of this study was to measure concentrations of odor in the piggery by season and growing, and to measure concentrations of odor at boundary area. So, we investigated the raising managements, manure managements, and methods of reducing odor according to farm scale. We found that concentration of ammonia gas in the swine fattening piggery in winter was the highest. This result is consistent with the lower ventilation rate to maintain Indoor temperature. In this result, there was no connection between farm scale and ventilating system. Concentration of ammonia gas was 1.64 ppm at one boundary area in the middle scale. $H_2S$, $CH_3SH$, $(CH_3)_2S$, and $(CH_3)_2S_2$ were below the standard of protection odor policy.

• Proceedings of the Korean Vacuum Society Conference
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• 2014.02a
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• pp.127-127
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• 2014

인체 내 소량의 생체성분(혈액, 소변 등)을 감지하는 바이오센서 기술은 질병 진단뿐만 아니라 예방 및 관리로 의료서비스 확대, 개인 맞춤형 진료 및 의료비 감소 효과를 가져올 수 있는 기술이다. 광바이오센서는 광학적인 측정방법을 이용하여 다양한 생화학물질들의 상호 반응을 검출해 낼 수 있는 바이오센서로 현재 활발하게 연구가 진행되고 있다. 광 바이오센서는 생체성분 내에 존재하는 전하를 가진 많은 이온들 및 Salt 농도 등에 영향을 받지 않기 때문에 나노 와이어를 이용한 FET (field-effect transistor)형 바이오센서에 비해 많은 장점을 가지고 있다. 일반적으로 광 바이오센서는 형광물질, 인광물질, 발색물질, 방사선 물질 등의 발광물질을 인식물질에 표지하여 인식물질과 분석물질과의 반응유무를 표지된 발광물질의 광학 신호를 감지하여 분석물질을 검출해내는 표지식 광 바이오센서 기술이 상용화되고 있다. 그러나 이러한 분석 방법은 민감도는 우수하지만 분석 시간이 매우 느리고, 고가의 분석 장비 및 복잡한 제조 공정 등의 단점들을 가지고 있다. 이러한 단점들을 극복하기 위하여 생화학 반응 유무를 표지물질 없이 광학적 방식으로 직접 측정할 수 있는 비표지식 광 바이오센서 기술이 최근 들어 많이 연구되고 있다. 본 논문에서는 광파장 이하의 주기를 가진 주기적 공진 격자 표면에서 일어나는 바이오 항원-항체 반응에 대한 공진 반사 파장을 측정하여 생체성분 내에 존재하는 바이오 항원을 고감도로 검출할 수 있는 비표지식 공진반사광 바이오센서 기술을 소개하고자 한다. 공진반사광 바이오센서를 이용하여 human serum내에 존재하는 심근경색 마커인 troponin I (cTnI), creatine kinase MB (CK-MB), myoglobin (MYO)을 0.1 ng/mL 이하의 농도까지 고감도로 측정할 수 있었다.

• Journal of Life Science
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• v.26 no.12
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• pp.1415-1421
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• 2016

This study was worked to investigate the antioxidant activity and the blood circulation improvement effect of two Hibiscus syriacus extracts divided into fermented H. syriacus extract and non-fermented H. syriacus extract. As the results of in vitro experiment, both of fermented H. syriacus extract and non-fermented H. syriacus extract had the DPPH free radical scavenging effect and the high contents of polyphenol and flavonoid known as antioxidant components in dose-dependent manner. Six weeks female C57BL/6 mice were divide into four groups and fed high diets for 28 days. Also fermented H. syriacus extract and non-fermented H. syriacus extract was daily intraperitoneal administration for 28 days at 2 mg/kg of body weight of mice. In vivo C57BL/6 mice experiment of normal diet group (NOR), high-fat diet group (CON), high-fat diet plus fermented H. syriacus extract group (FHS) and high-fat diet plus non-fermented H. syriacus extract group (NFHS), each of total cholesterol, triglyceride and low density lipoprotein (LDL) was decreased in both of FHS and NFHS groups, meanwhile high density lipoprotein (HDL) was increased (p<0.01). Conclusion, the results confirmed that H. syriacus containing the high contents of the antioxidant activity components had the significant effects of blood circulation improvement.

• Journal of IKEEE
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• v.24 no.2
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• pp.673-676
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• 2020

In this paper, we propose a whole-body management system using ultra-low temperature cyclical cooling method combined with IT technology. The proposed system has the following characteristics. First, it minimizes maintenance costs by circulating nitrogen gas cooled by ultra-low temperature inside the controller. Secondly, based on the information measured by the temperature sensor and oxygen concentration sensor, nitrogen gas is supplied to provide safe ultra-low temperature whole-body management. Thirdly, after entering the user's height, it provides convenient, ultra-low temperature whole-body care that can be controlled using an automatic lift. Fourth, it provides an easy-to-access, easy-to-manage GUI and a manager-only web program for whole-body management system operation. The results tested by the authorized testing agency to assess the performance of the proposed system were measured in the range of ±5%, the world's highest temperature sensor accuracy, and a range of -110℃ to -150℃ greater than the world's highest whole-body management temperature range(-110℃ ~ -140℃). In addition, humidity was measured at less than 40%, the world's highest, and oxygen concentration was more than 18%, the world's highest. Therefore, the effectiveness of the methods proposed in this paper was demonstrated because they produced the same results as the world's highest levels.

• Journal of the Korean Society of Radiology
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• v.14 no.5
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• pp.635-642
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• 2020

The purpose of this study was to analysis the effects of shielding area of field configuration with changing of sensitivity and density on tube current (milliampere-seconds, mAs) and image quality in automatic exposure control (AEC) system. The equipment used a digital radiography device (Digital Diagnost, Philips, Netherlands), which has a integral type with an X-ray tube and an indirect digital detector. The AEC system conditions were consisted of 9 setting environments, that mode changing of the sensitivity (S200, S400, S800) and the density (+2.5, 0, -2.5). The tube current evaluated automatically exposed mAs under 81 combination conditions crossed by AEC conditions in fixed at 40 kVp. The image quality evaluated the radiographic images that selected valid images by visual assessment the radiographic images of the self-produced conical pyramid phantom and then measured their signal to noise ratio (SNR). As a result, the maximum tube current was 60.0 mAs that automatically exposed conditions were the 100% of shielding area and the sensitivity of S200 and the density of +2.5. The minimum tube current was 0.9 mAs with non-shielding area and the sensitivity of S800 and the density of -2.5. When the shielded area 0% with the sensitivity of S200 and the density of +2.5, the maximum SNR was the highest as 25.2. But when the shielded area 25% with the sensitivity of S800 and the density of -2.5, the minimum SNR was the lowest as 4.7.

• Proceedings of the Optical Society of Korea Conference
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• 2002.07a
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• pp.178-179
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• 2002

최근에 화학, 임상병리, 환경 감시 등의 분야에서 산소센서의 수요가 점차 증가하고 있다. 이러한 산소 센서 중에 가장 많이 쓰이는 방식은 산화물 전극을 사용하는 amperometric 방법이지만 이 방법들은 장기간에 걸쳐 볼 때 산화물 전극의 오염, 외부 자기장의 간섭 등의 제점 때문에 산소를 측정하는데 많은 어려움이 있다. (1) 따라서 최근에는 빛과 유기염료를 통하여 산소의 농도가 증가할수록 세기가 quenching이 되는 원리를 이용한 산소센서의 연구가 이루어졌다. (중략)

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2010.06a
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• pp.225-225
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• 2010

박막 방식의 CIGS 태양전지는 공정이 복잡하고 대면적화가 어렵다는 단점을 가지고 있다. 이를 개선하기 위하여 후막 방식을 이용한 CIGS 태양전지에 대한 연구의 필요성이 대두되어지고 있다. 스크린 프린팅과 같은 후막공정은 나노 CIGS powder가 필요하다. CIGS 합성 방법 중에 solvothermal 방식이 다른 방식에 비해 균일한 크기의 구형의 나노입자를 대량생산이 쉽기 때문에 많이 연구되어지고 있다. 선행 연구 결과들은 CIS, CIGS 및 CGS는 solvothermal 법으로 합성 시 3개의 상이 모두 합성되며, 합성조건에 따라 상의 조성의 조절이 되지 않는다. 따라서 현재까지 solvothermal 법으로는 단일상의 CIGS 상의 합성이 보고되지 않고 있다. 본 연구에서는, solvothermal 방식을 이용하여 후막공정을 위한 CIGS powder를 합성하였다. 원료, 용매 및 합성 온도 등의 변화에 따른 상의 변화를 측정하였고, 원료의 농도에 따른 powder의 크기 및 형상을 제어 하였다. 또한 CIGS powder를 이용하여 페이스트을 제조한 후, 이 페이스트를 가지고 태양전지를 위한 치밀한 후막을 제조할 수 있었다.