• Korea journal of population studies
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• v.35 no.1
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• pp.53-75
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• 2012

This study aims to identify and evaluate the contents of ageism and to develop instrument of ageism. Ageism instrument development remains a necessary in aging research, for the explication of actual condition of ageing. The current study describes multidimensional view of ageism toward aging and the elderly. After pre-test and review of professionals, 31 items was constructed. Data were obtained from KGSS Survey of 1535 participants. The sample was randomly divided into two group to test reliability and validity of the scale. Finally, the 23-items with seven factors were suggested, based on the internal reliability and exploratory factor analysis with the first group. Another group were conducted confirmatory factor analysis. The results showed that the final 23-item scale with seven factors had a good model fit. Development and refinement of ageism scale are necessary elements for proceeding beyond theoretical and empirical discussions in ageism. It also provides a implications for current views of ageism and strategies for reducing ageism.

• 한국노년학
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• v.36 no.4
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• pp.1109-1124
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• 2016

We examined the effect of stereotype threat (STT) on spatial working memory and facial emotion recognition in Korean elderly. In addition, we investigated the role of expected moderator such as self-perception of aging. Seventeen seniors (male=7) received basic cognitive tests including K-WMS-IV, MMSE and answered self-report questionnaires including self-perception of aging, anxiety of aging, attitude toward aging and age identity on the first visit. On the second visit, they were exposed to negative stereotype by reading a script detailing cognitive decline related to aging while a control group was exposed to a neutral content. Following the exposure, they were tested on a spatial-working memory task (Corsi-block tapping task) and emotion recognition task (facial expression identification task). The results showed that the seniors exposed to STT showed significantly lower performance on emotion recognition task (p < .05) (i.e., especially on the more difficult facial stimuli). In addition, there was a significant interaction between STT and self-perception of aging (p< .05), indicating that those who have positive self-perception of aging did not show impairment in emotion recognition task and difficult spatial working memory task under STT. On the other hand, those with negative self-perception of aging showed impaired performance under STT. Taken together, the current study suggests that being exposed to STT could negatively influence cognitive and emotional functioning of elderly. Interestingly, having a positive self-perception of aging could protect the underperformance caused by STT.

• Journal of Life Science
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• v.19 no.4
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• pp.436-441
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• 2009

B23/nucleophosmin, a nucleolar protein, translocates into the nucleus from the nucleolus when cells are damaged by extracellular stresses. Recently, it was shown that such translocation of B23/nucleophosmin in normal fibroblasts under stress conditions increases both the stability and activation of the p53 protein by disrupting its interaction with MDM2. Senescent cells have a single large nucleolus and a diminished capacity to induce p53 stability upon exposure to various DNA damaging agents. To investigate the role of B23/nucleophosmin in p53 stability in senescent cells, we established a senescence model system by expressing the ras oncogene in IMR90 cells. The stability of p53 was reduced in these cells in response to nucleolar stress, although the level of B23/nucleophosmin protein was not changed. In addition, p53 did not accumulate in the nucleus and B23/nucleophosmin did not translocate into the nucleoplasm. The binding affinity of B23/nucleophosmin with p53 was reduced in senescent cells, whereas the interaction between MDM2 and p53 was stable. Taken together, the stability of p53 in ras-induced senescent cells may be influenced by the ability of B23/nucleophosmin to interact with p53 in response to nucleolar stress.

• 한국벤처창업학회:학술대회논문집
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• 2021.11a
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• pp.125-128
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• 2021

한국은 2025년 전체 인구 중 65세 이상 인구가 20%을 상회하는 초고령 사회 진입이 전망되면서 노화수준에 맞는 고령친화적인 제품서비스 공급이 요구된다. 특히 시니어 소비자가 사용하기 편리한 인터페이스를 갖춘 서비스가 필요하다. 이에 시니어들은 노화(aging)에 대한 문제의식에 비용을 지불하며 젊은 소비자들과 유사한 소비행태를 보이고, 노화 수준별 건강 유지 및 건강 불안, 돌봄 공백, 사회적 고립 증가 등 사회문제가 복합적으로 심화되면서 고령친화적인 스마트한 Aging Service 공급이 요구된다. 이러한 시기와 맞물려 with코로나시대 시니어 소비자가 사용하기 편리한 인터페이스를 갖는 제품·서비스로 4차 산업혁명의 중심인 AI(Artificial Intelligence)와 정보통신 기술의 노력이 가시화되고 있다. 따라서 IT 기술에 덧입혀 시니어들의 욕구에 부합하는 AI 음성인식 기능을 탑재한 제품 및 서비스가 향후 고령친화산업 성장을 주도할 것으로 전망된다. 이에 본 연구는 '고령친화 AI 음성 O2O 서비스'의 서비스 가치가 태도와 이용의도에 영향을 미치는가를 분석하기 위해 선행이론을 토대로 전문가 델파이 방법을 통해 고령친화 AI 음성 O2O 서비스의 정의를 도출하고 실증분석으로 '고령친화 AI 음성 O2O 서비스'의 서비스가치(상황기반 제공성, 즉시연결성, 위치정확성)와 태도 및 이용의도간의 인과관계를 조사하기 위해 본 연구를 진행하였다.

• Journal of Digital Convergence
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• v.15 no.2
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• pp.493-501
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• 2017

This study aimed to present cosmetic countermeasures for preventing fast aging process in the middle age and accepting healthy aging both physically and mentally by investigating the perception of aging according to the health condition, lifestyle and psychological condition targeting mid-aged women in 40s to 50s residing in Seoul and Gyeonggi-do Province. The data collection period was from July 25 to Sept 1, 2015. The data was analyzed by descriptive statistics, t-test, ANOVA, Pearson's correlation coefficients, and stepwise multiple regression. It was shown that as the age was higher, the menopause ratio was higher, drinking, exercise volume and hours of sleep were reduced and the stress and psychological pressure were higher. According to the menopausal status, the status of facial aging showed a significant difference (${\chi}^2=39.692^{***}$, p<.001), and it also showed a difference according to the status of leisure (hobby) activity (${\chi}^2=22.470^{***}$, p<.01). Also, as higher the age and closer to the menopause in items including the progress of aging, anxiety about aging and improvement efforts, more negative perception was shown, indicating that it is necessary to prepare cosmetic countermeasures for mid-aged women in like a second puberty 40s to 50s although aging and menopause around 50s are very natural. If a beauty alternative is provided, it will help them to have a successful retirement.

• 한국노년학
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• v.39 no.4
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• pp.825-846
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• 2019

This study aims to identify subgroups of ageism among young adults of age 20-39, and to examine its relationship to perceptions of generational conflict and elderly welfare policy. Latent Profile Analysis(LPA) was applied on the data 'Survey on Age Integration and Generational Integration', which was executed by institute for Age Integration Researchof Ewha Womans university, and descriptive statistics and cross-tabulation analysis were performed to examine the socio-demographic characteristics of each subgroup. Then, regression analysis was performed to observe the effect of the subgroups on the perceptions of generational conflict and elderly welfare policy. The results are as follows. The resulting subgroups of ageism among young adults were 'compound perception on aging and active age discrimination', 'medium-level aging anxiety and passive age discrimination', and 'low-level aging anxiety and beyond age discrimination'. Subgroups of ageism affected both perceptions of generational conflict and elderly welfare policy, whereas social support only affected perception of elderly welfare policy. Based on the results, political implications, such as activation of education on perception on aging, expansion of generational exchange for age integration, and renewal of social atmosphere for intergenerational coexistence, which will promote social integration

• The Journal of the Korean bone and joint tumor society
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• v.8 no.3
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• pp.69-75
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• 2002

Werner's syndrome is a rare autosomal recessive disorder manifesting as premature aging. It is also known to be characterized by a high frequency of malignant tumors, especially sarcomas. However, Werner's syndrome may be not only a premature aging disease but also a cancer syndrome, because the malignant tumors in these patients are different from those of normal population with respect to involved site, histological type, and age of onset. Recent studies found Werner's syndrome was caused by a mutation of Werner helicase suggesting that WRN helicase may participate in metabolism and repair of DNA. And a dysfunction of WRN helicase may induce the genomic instability causing somatic mutations. Further studies of Werner's syndrome associated with sarcoma might give much informations about the normal aging process and the pathogenesis of sarcomas.

• Journal of Korean Public Health Nursing
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• v.26 no.3
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• pp.440-452
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• 2012

Purpose: The purpose of this study was to provide basic data for use in development of strategy for healthy aging preparation and successful transfer to old age by identifying factors influencing quality of life of the baby boom generation. Methods: The data were collected from a total of 205 members of the baby boom generation(aged 48 to 56), and analysis was performed using descriptive statistics, t-test, ANOVA, Pearson's correlation coefficient, and stepwise multiple regression using the SPSS(Version19.0) program. Results: Burden for taking care of children, aging anxiety, preparations for old age, and quality of life according to the general characteristics and health-related characteristics commonly showed a significant difference in education level and presence of stress. The greater the more burden for taking care of children and the deeper the aging anxiety, the lower the quality of life, and the better prepared for aging, the higher the quality of life. Factors affecting quality of life in the baby boom generation included preparations for old age, burden for taking care of children, monthly household income, and quality of sleep. Explanatory power was 32%. Conclusion: For successful transition to old age and for improvement of quality of life in the baby boom generation, a comprehensive approach in micro and macro dimensions will be sought.

• Journal of Korean Public Health Nursing
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• v.30 no.1
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• pp.30-41
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• 2016

Purpose: This study was conducted to determine the effects of middle-aged women's social support, self-efficacy, and perceived health status on aging anxiety. Methods: Research subjects were 210 middle-aged women between 40 - 60 years living in G-city. Data were collected from July $21^{st}$ 2014 to August $8^{th}$ using a structured questionnaire and analyzed using t-test, One way ANOVA, and multiple regression analysis using the SPSS/WIN 21.0 program. Results: Aging anxiety showed statistically significant differences in religion (t=2.44, p=.015), satisfaction with married life (F=4.39, p=.014), type of leisure activity (F=8.09, p<.001), and number of friends (F=3.23, p=.024). Aging anxiety showed correlation with social support (r=-.21, p=.003), self-efficacy (r=-.46, p<.001), and perceived health status (r=-.33, p<.001). Factors affecting aging anxiety were self-efficacy (${\beta}=-.33$, p<.001), perceived health status (${\beta}=-.23$, p<.001), leisure activity type (${\beta}=-.16$, p=.010), and religious affiliation (${\beta}=-.17$, p=.038). The predictive power of these variables was 25% (F=18.63, p<.001). Conclusion: Nursing intervention strategies for improving self-efficacy, perceived health status, and leisure activity are required to relieve aging anxiety of middle-aged women.

• Journal of Digital Convergence
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• v.18 no.12
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• pp.343-351
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• 2020

The present study investigated the related variables of cognitive function, subjective cognitive decline and cognitive training effects. The cognitive training was composed of mete-cognitive education and cognitive task performing. Twenty older adults attended for 14 weeks and were tested before and after the training. Results show that their cognitive level was related with age, self-esteem and personality traits. And subjective cognitive decline was related depression, anxiety, personality traits, self-efficacy, self-esteem and subjective age, but it does not reflect objective cognitive impairments. Their cognitive test scores were enhanced after training in MMSE, memory and executive function, and enhanced scores were related with age, subjective cognitive decline, anxiety, self-efficacy, self-esteem, subjective age and personality traits. Findings suggest one's personality and psychological state need to be considered for the effects of cognitive training.