• Proceedings of the KOR-BRONCHOESO Conference
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• 1987.05a
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• pp.22.1-22
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• 1987

인후부, 하인두부 및 경부 등에 종양감각(lump sensation)등의 이상감각을 호소하는 globus 증후군은 Hippocrates가 처음 기술한 이래 많은 저자들에 의해 여러 가지 다양한 원인들이 기술되어 왔지만 아직 뚜렷한 병인이 밝혀지지 않은 상태로 기질적 원인에 대한 다각적인 연구가 진행중이다. 이에 저자들은 1986년 7월부터 1987년 2월까지 연세대학교 의과대학 이비인후과학 교실을 방문한 85명의 globus 증후 환자를 대상으로 전향적 연구를 시행 다음과 같은 결과를 얻었다. 1) 주증상은 무언가 걸린듯한 느낌이 가장 많았고(40.8%), 기타 점액객출 및 종양감각이 있었으며, 증상부위는 하인두부(26.8%) 및 윤상연골부(28.0%)가 많았고. 증상 유발인자로는 피로 및 신경과민증이 동반된 기질적 병변으로는 비후성 설편도염 및 인두염이 가장 많았다. 2) 비데오-식도조영술 검사상 27명(31.8%)에서 윤상인두근 이상수축이 있었으며 기타 식도복(3명), 식도점막이상(1명)등이 있었고 윤상인두근 이상수축이 있었던 환자군과 없었던 환자군 사이에 주증상, 증상부위, 동반증상, 기질적 병변 및 치료경과에는 차이가 없었으며 50% 이상의 수축을 보인 3명의 환자에서 내시경 검사상 이상소견은 관찰되지 않았다. 3) 치료는 특별한 기질적 병변이 없는 한 자세한 설명을 통한 치유의 확신감을 주고 필요에 따라 진정제, 제산제 및 cimetidine을 투여한 결과 65.3%에서 증상의 완전소실 및 현저한 호전이 있었고, 24.5%에서는 어느 전도의 호전이 있었으며, 10.2%에서는 증상의 호전이 없었다.

• Tuberculosis and Respiratory Diseases
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• v.45 no.1
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• pp.227-233
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• 1998

Typhoid fever is an acute systemic febrile disease caused by Salmonella typhi. The classic picture of the disease consists of prolonged continuous or remitting fever, abdominal pain, diarrhea, rose spots and delirium. Salmonella infection can lead to diffuse organ involvement., including bone, lung, thyroid, kidney, liver, spleen, heart, pericardium, intestine and skin and cause a variety of complications. Pulmonary manifestations occur in only 1 percent of the patients. Mild cough with sticky sputum is the earliest symptom and bronchitis, pneumonia and lung abscess were presented. Recently we experienced a case of typhoid fever complicated by bronchitis, dysplasia in a 37-year-old male physician who was improved with ceftriaxone and ciprofloxacin We report this case with a review of the literature.

• Tuberculosis and Respiratory Diseases
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• v.44 no.6
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• pp.1414-1418
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• 1997

Typhoid fever is an acute systemic febrile disease caused by Salmonella typhi. The classic picture of the disease consists of prolonged continuous or remitting fever, abdominal pain, diarrhea, rose spots and delirium. Salmonella infection can lead to diffuse organ involvement, including bone, lung, thyroid, kidney, liver, spleen, heart, pericardium, intestine and skin and cause a variety of complications. Pulmonary manifestations occur in only 1 percent of the patients. Mild cough with sticky sputum is the earliest symptom and bronchitis, pneumonia and lung abscess were presented. Recently we experienced a case of typhoid fever complicated by bronchitis, dysplasia in a 37-year-old male physician who was improved with ceftriaxone and ciprofloxacin We report this case with a review of the literature.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.2 no.2
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• pp.245-249
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• 1999

Childhood intestinal tuberculosis is difficult to diagnose for its protean clinical manifestations, especially in cases without pulmonary involvement. Differential diagnosis with Crohn's disease, inflammatory bowel disease and other malignancy is also important. Surgery has often been required for pathologic confirmation or therapy. Colonoscopy may be performed safely under consciousness sedation in children for bacteriologic and histopathologic confirmation of the biopsy specimen in addition to gross appearance of the lesion. We have experienced a case of intestinal tuberculosis presenting with chronic abdominal pain, diarrhea, weight loss and anemia in a 9 year old girl who was diagnosed by a colonoscopic examination and culture of the biopsy specimen from the ascending colon. The patient was managed with antituberculous drugs and recovered uneventfully.

• Tuberculosis and Respiratory Diseases
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• v.42 no.3
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• pp.394-399
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• 1995

Pneumocystis carinii pneumonia(PCP) remains the leading cause of death in patients with AIDS. Although the most common radiographic presentation of PCP is the development of diffuse, bilateral interstitial or alveolar infiltrates in 48 to 86 per cent of AIDS patients, PCP may also present with either a completely normal or only minimally abnormal chest radiograph in 6 to 23 per cent of patients. We experienced two patients with AIDS presenting high fever and chest pain but normal chest radiograph, who had been proved to have PCP by bronchoalveolar lavage and trans-bronchial lung biopsy.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.14 no.2
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• pp.181-186
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• 2011

Eosinophilic gastroenteritis is a rare disease occurring especially in children, and shows various nonspecific presentations with infiltration of eosinophils in the gastrointestinal organs. The pathophysiology of eosinophilic gastroenteritis is not yet clearly known, but allergic reactions are suspected to be related with the disease. Eosinophilic gastroenteritis is categorized into the mucosal, muscularis and subserosal types based on which layer of the intestinal wall is involved. There are different clinical manifestations according to the involved layer. Most cases to date have responded well to steroid therapy. In this study, we diagnosed and treated a case of non-IgE-mediated, subserosal eosinophilic gastroenteritis in a child with abdominal pain, diarrhea and ascites.

• Journal of The Korean Society of Clinical Toxicology
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• v.13 no.2
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• pp.87-94
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• 2015

Purpose: We investigated comparison of clinical characteristics and prognosis by initial endoscopic severity in caustic injury and then discussed predisposing factors which can be helpful in predicting the prognosis and determining the treatment. Methods: This study was a retrospective review of medical records from patients over the age of 15, who underwent initial endoscopy for caustic injury from April 2007 through November 2014. Patients were classified according to two groups based on the initial endoscopic finding by Zargar's classification: patients with grade 0, I, IIa at esophagus (low risk group) and patients with grade IIb, IIIa, IIIb at esophagus (high risk group). The two groups were then compared. Results: A total of 55 patients were included (low risk group [n=44] vs. high risk group [n=11]). Old age (p<0.001), large amount of ingestion (p<0.05), oropharyngeal symptoms (p<0.01), high SOFA score (p<0.001), high WBC count (p<0.05), low base excess (p<0.01), and HCO3 (p<0.05) were statistically significant factors in the high risk group. A poor prognosis was observed for hospital stay (p<0.001), ICU admission (p<0.001), mortality (p<0.01), and stricture (p<0.001) in the high risk group. Conclusion: Clinical characteristics including age, amount of ingestion, oropharyngeal symptoms, SOFA score, WBC count, base excess, and $HCO_3$ can be helpful in the decision to undergo initial endoscopy and risk assessment by initial endoscopic severity can be helpful in predicting prognosis and determining the treatment plan.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.11 no.2
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• pp.187-192
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• 2008

Most cases of mucosa-associated lymphoid tissue (MALT) lymphoma occur in adults. MALT lymphoma is very rare in children. Helicobacter pylori (H. pylori) infection is known to be an important etiologic factor predisposing to the development of gastric MALT lymphoma. A 12-year-old girl was admitted because of intermittent abdominal pain occurring over the preceding 2 years. Nodular gastritis of the stomach was demonstrated on endoscopy. H. pylori infection was confirmed using the rapid urease test and histopathology. Histopathological examination of gastric biopsy specimens revealed lymphoepithelial lesions pathognomonic of MALT lymphoma, and immunohistochemical staining for CD20 was diffusely positive. Therefore, the patient was diagnosed with gastric MALT lymphoma. Clinical manifestations and histopathologic findings compatible with MALT lymphoma improved with the eradication of H. pylori infection. We report a case of primary gastric MALT lymphoma in a child, associated with H. pylori infection and presenting as nodular gastritis.

• Tuberculosis and Respiratory Diseases
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• v.49 no.4
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• pp.502-507
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• 2000

Carcinoma of the prostate is a common malignancy affecting elderly men. Lung metastasis from prostate cancer occurs frequently, but tumor metastasis to the central bronchi that clinically mimics primary bronchogenic carcinoma are very rare. We report a 73-year old man with endobronchial metastasis from prostatic carcinoma presented with respiratory symptom cough. Diagnosis of tissues taken from materials which were used for bronchoscopic biopsy and prostate biopsy and immunohistochemical staining for prostate specific antigen (PSA) confirmed a case of endobronchial metastasis from prostatic carcinoma. Hormonal therapy (LHRH agonist) was applied to this patient.

• Journal of the Korean Society of Radiology
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• v.83 no.2
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• pp.400-405
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• 2022

Gastrointestinal stromal tumors (GISTs) are not uncommon and often cause gastrointestinal bleeding. GISTs occurring in the small intestine are occasionally difficult to identify by endoscopy and CT. In this case, the patient underwent CT three times before surgery, and the lesion was found to be located in a different area of the abdominal cavity on each CT scan. Moreover, the lesion was missed in the first two CT images because it was difficult to distinguish it from the nearby collapsed small intestine. The lesion was eventually detected through angiography; however, the correct diagnosis and treatment were delayed for 3 years because it was mistaken for a vascular malformation, which is the most common cause of obscure GI bleeding in elderly patients. This report emphasizes the need for interventional radiologists to be updated and vigilant of the angiographic features of GISTs to make an accurate diagnosis and establish a management strategy.