• Title/Summary/Keyword: 내분비질환

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Thymic Neuroendocrine Tumor (흉선의 신경내분비 종양)

  • 이응배;이상철;박태인;조준용;장봉현;이종태;김규태
    • Journal of Chest Surgery
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    • v.35 no.4
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    • pp.325-328
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    • 2002
  • The neuroendocrine tumor is a rare thymic neoplasm, which has been regarded as a distinct tumor from thymoma and originates from Kultschizky cell. The pathologic diagnosis of thymic neuroendocrine tumor has been on findings from light microscopy, immunohistochemical studies, and electron microscopy. About 50% of thymic carcinoids are seen with endocrinopathies. Recurrence and extrathoracic metastasis are characteristics of thymic carcinoids. Surgical removal of the initial and recurred tumor is considered to be the most effective treatment. The role of the adjuvant chemotherapy and radiotherapy is still uncertain. Herein we report a case of thymic neuroendocrine tumor, which was resected surgically.

Challenge Zone_소중한 당신의 체중계_과식 줄이기 - 비만 식사습관에 달렸다

  • Son, Bo-Deu-Ri
    • 건강소식
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    • v.36 no.2
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    • pp.6-8
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    • 2012
  • 비만이 되는 이유는 내분비질환이나 특정 약물 복용이 원인일 수도 있지만, 대개는 섭취한 영양분(에너지원)이 다 사용되지 않고 지방으로 변해 체내에 남기 때문이다. 그러므로 에너지 섭취가 많은 경우, 즉 너무 많이 먹거나 살찌기 쉬운 음식(단 음식, 기름진 음식)을 좋아하는 사람은 비만일 수밖에 없다.

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Molecular Genetic Diagnosis of Genetic Endocrine Diseases (유전성 내분비 질환의 분자유전학적 진단)

  • Choi, Jin-Ho;Kim, Gu-Hwan;Yoo, Han-Wook
    • Journal of Genetic Medicine
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    • v.7 no.1
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    • pp.16-23
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    • 2010
  • Many endocrine disorders have a genetic component. The genetic component is the major etiologic factor in monogenic disorders, while multiple genes in conjunction with environmental and lifestyle factors contribute to the pathogenesis in complex disorders. The development of the molecular basis of inherited endocrine diseases has undergone a dramatic evolution during the last two decades. The application of molecular technology allowed us to increase our understanding of endocrine diseases, and to impact on the practice of pediatric endocrinology related to diagnosis and genetic counseling. Identification of the mutation in the particular disease by genetic testing leads to precise diagnosis in the equivocal cases and prenatal diagnosis. However, clinicians should be cautious about determining therapeutic decisions solely on the basis of molecular studies, especially in the area of prenatal diagnosis and termination of pregnancy. This review describes an introduction to molecular basis of various inherited endocrine diseases and diagnosis by genetic testing.

Large Cell Neuroendocrine Carcinoma of the Lung - A case report - (대세포 신경내분비암-1례 보고-)

  • 김연수;류지윤;김민경;장우익;김욱성
    • Journal of Chest Surgery
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    • v.35 no.12
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    • pp.909-913
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    • 2002
  • The large cell neuroendocrine carcinoma is uncommon and its diagnostic criteria was recently established as pulmonary neuroendocrine carcinoma. A 74-year-old man who was a heavy smoker without symptoms was presented with a lung mass in right lower lobe. He was diagnosed as having large cell neuroendocrine carcinoma by needle biopsy. He was treated with right lower lobe lobectomy and mediastinal lymph node dissection. We experienced one case of large cell neuroendocrine carcinoma of lung and report it with reference.

Psychological Factors Affecting Endocrine Disease (내분비질환에 영향을 미치는 심리적 요인)

  • Joe, Sook-Haeng
    • Korean Journal of Psychosomatic Medicine
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    • v.6 no.2
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    • pp.221-227
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    • 1998
  • Although there has been a considerable research in psychoneuroendocrinology, particularly in relation to the biology of mood disorders, there has been a paucity of research regarding the effects of psychological factors on endocrine diseases. Of the existing literature, the most research is focused on diabetes mellitus, graves' disease. Especially diabetes appears to be the only endocrine disease that has been the focus of recent research studies. Most of the studies had retrospective designs or several methodological flaw. There has been no consistent results demonstrating that psychological factors affect the onset of diabetes mellitus. Several studies have suggested that psychological factors affect the course of diabetes. A small number of studies showed some evidence that psychological stress was associated with changes in glucose regulation in a subset of diabetic patients. There was also evidence to suggest that some temperament and coping skill influence glycemic control in child, adolescent diabetics. Studies of behavioral or psychosocial intervention on diabetic control have been small and have produced mixed results. There was a few controlled study suggested that stressful life events might be a causal role in Cushing's disease and Graves'disease, but there is no presently sufficient evidence to suggest that psychological factors affect the onset and the course of Cushing's disease and Graves' disease. In future, there is need for a well-designed biopsychosocial research with prospective designs, well defined patient population and control groups to study the relationship between psychological factors and endocrine diseases.

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