• The Journal of the Convergence on Culture Technology
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• v.10 no.4
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• pp.41-46
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• 2024

In this study, we sought to confirm the potential of the Chaetomorpha torta extract as a raw material for cosmetics. Accordingly, we sought to find the optimal extraction conditions for Chaetomorpha torta by ethanol concentration and to check whether it has an anti-inflammatory effect by confirming the inhibitory effect of pro-inflammatory cytokines (TNF-α, IL-1β, IL-6). The main contents of the experiment results are as follows. First, when DPPH radical scavenging ability and polyphenol yield were used as the criteria for optimal extraction conditions of Chaetomorpha torta, 70% concentration ethanol extract was most suitable. Second, as a result of cytotoxicity evaluation using Raw 264.7, no cytotoxicity was observed at concentrations below 100 ㎍/mL. Third, as a result of measuring the inhibitory effect of pro-inflammatory cytokines TNF-α, IL-1β, and IL-6 in LPS-induced Raw 264.7 cells, the production of all cytokines decreased in proportion to the concentration, and 100 ㎍/mL It was confirmed that the concentrations were 73.76±2.6%, 84.8±2.42%, and 91.91±0.47%, respectively, showing excellent anti-inflammatory properties. According to these research results, it appears that the extract of the Chaetomorpha torta can be valuable as a raw material for cosmetics with anti-inflammatory properties, and if research on antioxidant, antibacterial, and anti-inflammatory activities related to green algae is conducted more actively, marine resources can be used as useful basic data. It is believed that it will be.