• Title/Summary/Keyword: 기형성

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Korean Birth Defect Forum, KBDF (안까타운 기형, 소중한 생명 살리기 - 대한 선천성 기형 포럼)

  • 박인숙
    • 가정의 벗
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    • v.37 no.6 s.430
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    • pp.4-5
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    • 2004
  • 선천성 기형의 종류는 매우 다양하며 완치가 가능한 기형도 많다. 그러므로 선천성 기형이 있다고 무조건 자랑할 필요는 없으며 전문가의 상담이 필요하다. 감기약 한번 잘못 먹어서, 또는 임신인 줄 모르고 한번 찍은 가슴 X-선 사진으로 인공임신중절을 하는데 이는 고쳐져야 할 관행이다.

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Clinical Approaches to Patients with Congenital Malformations (선천성 기형의 임상적 접근)

  • Lee, Jin-Sung
    • Journal of Genetic Medicine
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    • v.5 no.2
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    • pp.94-99
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    • 2008
  • Congenital malformation is observed in about 2-5% of newborns and is a leading cause of infant mortality. The prognosis of malformation is dictated mainly by proper treatment followed by correct diagnosis at an early age. In practice, etiological consideration and classification of a malformation is critical for diagnosis. Malformations can be classified as belonged to minor or major anomaly. It is clinically important to clarify the pathogenesis of the anomalies among malformation, deformation, disruption, and dysruption. Genetic counseling aids this process by helping patients or family members understand and the nature of the malformation and risk assessment.

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Simple Congenital Cystic Adenomatoid Malformation with a Feeding Artery (영양동맥을 동반한 단순 선천성 낭종성 선종양 기형)

  • Kim, Jae-Jun;Wang, Young-Pil;Park, Jae-Kil
    • Journal of Chest Surgery
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    • v.43 no.4
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    • pp.450-453
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    • 2010
  • CCAM with no other anomalies such as sequestration receives its blood supply from the pulmonary artery. Our case presented with a simple CCAM and no other anomalies but with a feeding artery. Although preoperative evaluation may not show feeding arteries, they may exist in congenital cystic lung diseases.

A case of Congenital Cardiac Anomaly Associated with DiGeorge Syndrome (DiGeorge증후군에 동반된 선천성 심장기형 치험 1례)

  • 손영상;김태식;황재준;김학제;박선화
    • Journal of Chest Surgery
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    • v.32 no.6
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    • pp.584-587
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    • 1999
  • The DiGeorge syndrome is a rare congenital abnormality consisting of aplasia or hypoplasia of the thymus and parathyroid glands resulting from malformation of the third and fourth pharyngeal pouches. This syndrome usually includes congenital cardiac anomalies and abnormal facial features. We experienced a case of congenital cardiac anomaly associated with DiGeorge syndrome. The patient was 1 month old boy weighing 3.5 kg. The congenital cardiac anomalies included ventricular septal defect, atrial septal defect, coactation of aorta, and patent ductus arteriosus. We performed one-stage operation with two separate incisions for these cardiac anomalies. Postoperative course was uneventful and the patient at 6 months of follow up is doing well.

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Simulation System for Quantitative Deformity Analysis (정량적 기형분석을 위한 시뮬레이션 시스템)

  • 홍헬렌
    • Proceedings of the Korea Society for Simulation Conference
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    • 2000.04a
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    • pp.154-160
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    • 2000
  • 기형부위의 구조적 복합성으로 인하여 부상이나 질병을 진단하거나 치료계획을 수립하는데 있어 많은 어려움이 있다. 본 논문에서는 기형부위의 정량적 분석을 위한 시뮬레이션 시스템을 설계하고 구현하였다. 본 시뮬레이션 시스템은 기형부위간 관계를 정의하고 정량적으로 분석하기 위하여 2차원 진단영상들을 공간적으로 구성하여 가시화하고 단일 객체 및 다중 객체의 이동, 회전, 확대/축소, 컬러링 등과 같은 조작기능을 제공하며, 기형부위의 길이, 체적, 각도 등의 측정치를 제공한다. 본 시뮬레이션 시스템은 사용자가 작업부하량을 줄이기 위하여 클라이언트-서버 구조로 이루어졌으며, 시스템간 사용되는 메시지 처리를 위한 메시지 제어기, 기형부위별 가시화와 조작을 위한 기형가시화 및 조작기, 기형 부위의 수치적 분석을 위한 정량적 분석기, 그리고 각종 환자 정보를 위한 영상 데이터베이스 관리기로 구성된다. 본 시뮬레이션 시스템은 기형부위의 효과적인 가시화와 조작 뿐 아니라 정량적 분석치를 제공함으로써 보다 정확한 기형분석에 많은 도움을 줄 수 있으며, 범용의 데스크탑 컴퓨터상에서 편리한 사용자 인터페이스를 통하여 서버에 접속하여 시뮬레이션 시스템을 사용함으로써 보다 많은 사용자들이 동시에 사용할 수 있는 이점이 있다.

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Vascular Malformation of Flexor Hallucis Longus Muscle Associated with a Flexion Deformities of Toes: A Case Report (장무지 굴곡근의 혈관성 기형에 동반된 발가락의 굴곡 변형: 증례 보고)

  • Ahn, Jong-Chul;Kim, Jung-Rae;Shin, Ji-Hoon;Shin, Duk-Seop
    • The Journal of the Korean bone and joint tumor society
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    • v.17 no.2
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    • pp.100-105
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    • 2011
  • Vascular malformations may typically present with palpable mass that can be either asymptomatic or can present with symptoms including swelling and pain. On rare occasions, vascular malformation of muscle may produce joint deformities caused by contracture of the involved muscle. When vascular malformation involves the flexor muscle of the leg, ankle equinus deformity may occur. However, there are no reports of toe deformities secondary to intermuscular or intramuscular vascular malformations of flexor muscles of toe. Thus, we report a case of vascular malformation of flexor hallucis longus muscle with flexion contracture of toes in a 40-years-old woman who was treated with surgical excision.

Effect of Environmental Factors on Appressorium Formation of Colletotrichum truncatum (환경조건(環境條件)이 대두(大豆) 탄저병균(炭疽病菌)(Colletotrichum truncatum)의 부착기형성(附着器形成)에 미치는 영향(影響))

  • Do, Eun-Su;Paik, Su-Bong
    • The Korean Journal of Mycology
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    • v.15 no.3
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    • pp.142-148
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    • 1987
  • The results investigated of the effect of light, pH, and nutrients in vitro and the levels of fertilizer(P,K and Ca) in vivo in order to find out the effect of environmental factors in forming an appressorium of Colletotrichum truncatum were as follows; The ratio of appressorium formation promoted more in a light treatment than in a dark treatment according to investigation after three and six hours passed away. But after the period, the ratio of appressorium formation promoted highly in both treatments. Reasonable pH of appressorium formation was pH 6-pH 8. The ratio of appressorium formation was the most favorable at none nutrient level in every treatment of C-source and N-source, and suppressed in a high concentration of C-source and N-source. But according as the time passed away, the ratio of appressorium formation promoted in C-source and N-source. When their quantities were increased in P and K treatments, the ratio of appressorium formation was somewhat suppressed but it was highly suppressed in the gradual order of none fertilizer level < standard fertilizer level < doubled fertilizer level in Ca treatment according to investigation after the first three hours passed away. But after the period, the ratio of appressorium formation promoted highly regardless of the level of fertilizer.

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Two Cases of Fourth Branchial Anomaly: Pyriform Sinus Fistula Treated by Chemical Cauterization (제 4 새낭 기형 2 례: 화학소작에 의한 이상동누공 치험)

  • 김광현;신진성;성명훈
    • Proceedings of the KOR-BRONCHOESO Conference
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    • 1993.05a
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    • pp.109-109
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    • 1993
  • Fourth branchial pouch anomaly is an extremely rare condition involving the pharyngeal apparatus with only about 30 cases having been reported in the last 20 years. It almost invariably occurs on the left side and typically presents with repeated episodes of neck swelling, recurrent thyroiditis, or repeated bouts of retropharyngeal abscess. This is a presentation of 2 patient with pyriform sinus fistula, presumably of fourth branchial origin, which, were successfully closed with 10ole trichloroacetic acid chemical cautery. Details of the cases along with the summary of embryology and fourth branchial anomaly are given.

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Basic study on the Behavior Characteristics of Liquid-phase Spray with Phase Change (상변화를 동반한 액상분무의 거동 특성에 관한 기초 연구)

  • Yeom, J.K.
    • Journal of Power System Engineering
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    • v.14 no.2
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    • pp.5-11
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    • 2010
  • 분사연료의 혼합기형성과정 최적화를 통한 연소제어 기술은 디젤기관의 기관운전 및 배기특성을 향상시키기 위하여 매우 중요하다. 또한 분무의 혼합기형성 최적화를 위해서는 분사된 연료와 주위기체와의 혼합과정에 영향을 미치는 분무내부의 유동특성에 대한 연구는 필수 불가결하다. 따라서 본 연구에서는 고온 고압의 증발장에서 분무의 액상 거동에 주목하고, 그 거동특성을 통하여 증발디젤분무의 혼합기형성을 해석한다. 비정상 증발분무의 중심축에 레이저 시트광을 입사한 후, 액상분무 액적의 Mie 산란광에 의한 2차원 화상을 획득하여 증발분무 액상의 속도분포 및 와도(vorticity) 등을 구하였다. 분무의 속도분포 및 와도는 2차원 화상에 PIV법을 적용하여 계산하였다. 그림 1에 본 연구에서 구한 속도분포의 일례를 보인다. 본 연구의 결과로 상변화를 동반하는 비정상 증발장에서 구한 분무액상의 거동 특성은 상변화가 일어나지 않는 비증발장에 있어서의 분무거동특성과 유사함을 확인하였다.

A Study on the Evaluation of Teratogenecity of Chemical by Korean Brown Frog Embryo, Rana dybowskii (산개구리 배아를 활용한 화학물질의 기형성 평가에 관한 연구)

  • Ko Sun-Kun
    • Korean Journal of Environment and Ecology
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    • v.18 no.3
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    • pp.333-339
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    • 2004
  • The Frog Embryo Teratogenesis Assay-Xenopus(FETAX) protocol was recently adopted as a valuable tool fur evaluating chemical toxicity and the effect of environmental contaminants in frogs. In this study, the teratogenecity of NiCl$_2$, Carbofuran, Diazinon were determined in the Korean frog, Rana dybowskii using the FETAX protocol. The mortality rate and the percentage of malformed larvae were investigated by probit analysis, The teratogenic concentrations(EC$_{50}$) of NiCl$_2$, Carbofuran and Diazinon were 0.4 and 1.6 and 1.9 mg/1. The embryolethal concentrations(LC$_{50}$) of NiCl$_2$, Carbofuran and Diazinon were 17.6 and 41.5 and 20.2mg/1. The teratogenic indices (TI=LC$_{50}$/EC$_{50}$) were 43.8 for NiCl$_2$, 26.0 for Carbofuran and 10.6 for Diazinon. NiCl$_2$, Carbofuran and Diazinon were shown to be potent teratogens for Rana dybowskii embryo, causing concentration related increase of edema, tail and abdomen. The study results reveal that NiCl$_2$, Carbofuran and Diazinon suppress the development of embryos at relatively low concentrations. Therefore, the Rana dybowskii embryo teratogenesis assay system was proven to be a useful tool to evaluate the toxicity of environmental pollutants.lutants.