• Title/Summary/Keyword: 기형발생

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원전주변지역의 기형송아지발생에 관한 병인학적 연구 2. 기형송아지의 형태학적 소견

  • 이차수;김성호;박청규;정규식;정원일;정재용;임태선;정혜진;김세라
    • Proceedings of the Korean Society of Veterinary Pathology Conference
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    • 2001.09a
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    • pp.35-35
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    • 2001
  • 최근 원전주변지역을 중심으로 한 기형가축이 발생함에 따라 이의 원인을 규명하고 사육농민들의 불안해소와 경제적 손실을 방지하기 위하여 역학적 조사, 혈청학적 검사를 실시하였으며 기형송아지 및 유ㆍ사산 태아 등의 이상산을 중심으로 임상적 및 병리학적 검사를 실시하였다. 2000년 2월부터 2001년 8월까지 총 19개월간 수집된 54 두의 이상산 중 45두가 기형송아지였다. (중략)

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Types of Mentum Deformity for Chironomus riparius Exposure to DEHP (DEHP에 노출된 Chironomus riparius의 하순기절에 나타난 기형 유형들)

  • Kwak, Inn-Sil;Jeong, Gyeong-Suk
    • Korean Journal of Environmental Biology
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    • v.26 no.1
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    • pp.36-41
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    • 2008
  • Induction of morphological deformities in Chironomus riparius larvae was assessed after exposure to 0.3, 1, 10 and 30 ${\mu}g\;L^{-1}$ potential endocrine disruption chemicals, Diethylhexyl phtalate (DEHP). We observed and subdivide types of mentum deformities and counted the incidence of mentum deformities. The mortality was not increased according to concentrations of DEHP, while was depend on the exposed days. The incidence of mentum deformities for MLT (median lateral teeth), LT (lateral teeth), and MIX (MLT+LT) of the mentum morphological structure showed MLT (2.8$\sim$11.4%)>LT (2.8$\sim$2.9%)>MIX (2.8$\sim$3.0%). The type of mentum deformities on C. riparius was classified six groups following exposure to DEHP. The incidence rate was occupied following to tooth addition (4.3%), tooth split (2.8%), tooth deletion (2.4%), tooth fusion (1.4%), $K"{o}hn$ gap (0.5%) and abnormal shape (0.5%). Especially tooth split and tooth fusion were observed in DEHP treated conditions.

Coexistence of the Absence of the Left Common Carotid Artery, a Common Origin of the Left External Carotid Artery and the Right Common Carotid Artery, and an Aberrant Right Subclavian Artery: A Case Report (좌경동맥 결손, 좌외경동맥과 우경동맥 공통줄기 기형 및 이상 우쇄골하동맥의 동반 발생: 증례 보고)

  • Soo Jeong Lee;Hye Jeong Choi;Sang Heum Kim
    • Journal of the Korean Society of Radiology
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    • v.82 no.4
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    • pp.948-952
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    • 2021
  • The absence of the common carotid artery (CCA) and the common origin of the left external carotid artery (ECA) and the right CCA are rare anomalies of the cervical vascular system. We report here a case involving the coexistence of these vascular anomalies with an aberrant right subclavian artery, which is a common congenital anomaly in the aortic arch, and review the embryologic mechanism and clinical importance of this case.

원전주변지역의 기형우발생에 관한 병인학적 연구 1. 역학적 조사

  • 이차수;김성호;박청규;정원일;박상준;임태선;김세라;박진형;권무수
    • Proceedings of the Korean Society of Veterinary Pathology Conference
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    • 2000.09a
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    • pp.31-31
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    • 2000
  • 최근 원전주변지역을 중심으로 한 기형가축이 발생함에 따라 이의 원인을 규명하기 위하여 우선 역학적 조사와 혈청학적 검사 및 기형송아지 , 유산·사산 태아 등의 수집가 검물을 중심으로 하여 병리학적 검사를 실시하였다. 원전주변 기형우 발생농가의 역학적 조사와 모우의 임상적 소견에서는 하동의 이상을 관찰할 수 없었다 . 수집된 가검물 (울진원전주변지역 : 3두, 월성원전주변지역 : 3두, 고리원전주변지역 : 3두, 기타지역 2두) 총 11개 농가 11두에 대한 병리학적 검사와 모우 및 자우의 혈청학적 검사에서 9두가 Akabane 병으로 진단되었고, 나머지 2 두는 곰팡이감염증 1두 그리고 간경화 l 두로 판정되었다. Akabane virus에 감염된 9두는 기형송아지, 유·사산태아로서 사지기형, 척추만곡 및 중추신경계이상(대뇌결손, 뇌수두증)등이 관찰되었다. (중략)

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Vascular Malformation of Flexor Hallucis Longus Muscle Associated with a Flexion Deformities of Toes: A Case Report (장무지 굴곡근의 혈관성 기형에 동반된 발가락의 굴곡 변형: 증례 보고)

  • Ahn, Jong-Chul;Kim, Jung-Rae;Shin, Ji-Hoon;Shin, Duk-Seop
    • The Journal of the Korean bone and joint tumor society
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    • v.17 no.2
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    • pp.100-105
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    • 2011
  • Vascular malformations may typically present with palpable mass that can be either asymptomatic or can present with symptoms including swelling and pain. On rare occasions, vascular malformation of muscle may produce joint deformities caused by contracture of the involved muscle. When vascular malformation involves the flexor muscle of the leg, ankle equinus deformity may occur. However, there are no reports of toe deformities secondary to intermuscular or intramuscular vascular malformations of flexor muscles of toe. Thus, we report a case of vascular malformation of flexor hallucis longus muscle with flexion contracture of toes in a 40-years-old woman who was treated with surgical excision.

Prenatal Deaths and External Malformations Caused by X-Irradiation during the Preimplantation Period of ddy Mice (임신 ddy Mice에서 착상전기 방사선 조사에 따른 산전 사망 및 외부 기형 발현)

  • Ro, Hee-Jeong;Choi, Ihl-Bhong;Gu, Yeun-Wh
    • Radiation Oncology Journal
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    • v.16 no.3
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    • pp.233-243
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    • 1998
  • Purpose : To evaluate the effects of X-irradiation on prenatal deaths, i.e., preimplantation deaths, embryonic deaths and fetal deaths, and on external malformations in precompacted preimplantation ddy mice Materials and Methods : Pregnant mice (n=85) obtained by limiting the mating time to from 6 to 9 A.M., were segregated into 11 groups. The first five groups (n=26) were irradiated with X-ray doses of 0.1 0.5, 0.75, 1.5, and 3 Gy, respectively, at 24 h post conception (p.c.) of the preimplantation Period. The second five (n=27) groups were irradiated at the same X-ray doses, respectively, but at 48 h p.c. of the preimplantation period. The last group (n=32) was the control group. The uterine contents were examined on the 18th day of gestation for prenatal deaths and external malformations. Results : 1) A statistically significant increase in preimplantation deaths with increasing dose was observed in the experimental groups irradiated at 24 h p.c. and in the groups irradiated at 48 h p.c., as compared to the control group. The threshold dose was close to 0.05 Gy and 0.075 Gy for the irradiations at 24 h p.c. and 48 h p.c. respectively. 2) A statistically significant increase in embryonic deaths with increasing dose was observed in all irradiation groups, except the group irradiated with a dose of 0.1 Gy at 48 h p.c.. 3) No fetal deaths were found in any experimental group. 4) In the experimental groups irradiated at 24 h p.c. anomalies increased with statistical significance, as compared with the control group : 2 exencephalies, 2 open eyelids, 3 anophthalmias, 2 cleft Palates, 2 gastroschisis, 1 abdominal wall defect. 1 leg defect, and 2 short tail anomalies: the threshold dose for external malformations was close to 0.2 Gy at 24 h p.c.. In the groups irradiated at 48 h p.c., 1 open eyelid and 2 short tail anomalies were observed, but there was no statistical significance in those malformations. Conclusion : The results of this study reveal that X-irradiation of precompacted preimplantation ddy mice causes not only preimplantation deaths and embryonic deaths but also external malformations. In addition, external malformations were observed in our experiments at diagnostic doses, including 0.1 and 0.5 Gy. For this reason, we recommend that irradiation should be avoided during the preimplantation period by applying Rugh's 10-day rule.

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Mediastinal Teratoma: A Pictorial Essay (종격동 기형종: 임상 화보)

  • Sang Gyun Kim;Won Gi Jeong;Sang Yun Song;Taebum Lee;Jong Eun Lee;Hye Mi Park;Yun-Hyeon Kim
    • Journal of the Korean Society of Radiology
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    • v.83 no.3
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    • pp.597-607
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    • 2022
  • The mediastinum is the most prevalent site of extragonadal teratomas. Patients with mediastinal mature teratomas are usually young adults, and the condition does not show significant sexual differences. Mediastinal teratomas are mostly located in the anterior mediastinum. Patients are usually asymptomatic, although they can have several complications when the teratomas become large or rupture. Most mediastinal teratomas can be diagnosed using CT. Diagnosing ruptured or malignant teratomas is challenging because of their atypical clinical and radiological presentations. In this article, we describe various manifestations of mediastinal teratomas, with an emphasis on radiologic features.

혈관내 Alcohol 주입법에 의한 두경부 정맥 기형증의 치험 2례

  • Kim, Hyeong-Gon;Park, Gwang-Ho;Lee, Ui-Ung;Kim, Jun-Bae;Ju, Jae-Dong;Kim, Dong-Ik
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.13 no.4
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    • pp.444-449
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    • 1991
  • 저자등은 5세 여아의 좌측 하순부에 발생한 정맥기형증 및 25세 여자 환자의 좌측 교근부에 발생한 정맥 기형증에 대하여 비와과적 방법인 직접알콜 주입에 의한 sclerosing therapy 치료한 결과, 별다른 후유증이나 재발의 소견없이 심미적, 기능적으로 양호한 결과를 얻었기에, 과거 sclerosing solution의 단점을 보완한 순수한 알콜제재의 사용을 문헌고찰과 함께 보고하는 바이다.

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The Incidence of Abnormalities in Bullfrogs, Rana catesbeiana, and Their Heavy Metal Accumulations in the Yeongsan River System (영산강 수계에서 채집된 황소개구리의 기형 양상 및 체내 중금속 축적)

  • 이두표;고선근
    • Korean Journal of Environment and Ecology
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    • v.15 no.2
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    • pp.153-158
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    • 2001
  • 영산강 수계의 습지생태계 모니터링의 일환으로 4개 지역을 선정하여 황소개구리 205개체를 채집하여 이들의 외부기형 출현율 및 양상을 조사하고 그들의 체내 조직에 축적된 중금속 농도를 분석하였다. 황소개구리의 기형 출현율은 6.8%로 다른 척추동물에서의 자연발생률 3%보다 높았으며, 기형은 모두 앞 또는 뒷발갉에서 나타났다. 유형별로 보면 결손(Ectrodactyly)이 64.3%로 가장 많았고 다음으로 확장(Dilation)이 28.6%, 절단(Truncation) 7.1%의 순이었다. 정상과 기형 개체간에 중금속의 농도를 조직별로 비교해 본 결과 기형개체의 신장에서 Mn은 4배, Zn 은 1.5배, Cu은 7배, Pb는 8배, Cd는 7배 정도 높았다. 또한 기형 개체에서는 이들 원소의 조직분포 패턴도 변화한 것으로 나타났다. 이러한 결과들로부터 황소개구리는 습지생태계의 모니터링 시료로서 유용하게 이용될 수 있음을 알 수 있었다.

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Benign Mediastinal Cystic Teratoma Complicated by Cardiac Tamponade due to Trauma (외상에 의하여 심장눌림증을 유발한 종격동 양성낭기형종)

  • Choe Ju-Won;Kim Yong-In
    • Journal of Chest Surgery
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    • v.39 no.9 s.266
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    • pp.729-732
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    • 2006
  • Mediastinal teratoma is one of the most common lesions found in the anterior mediastinum, accounting for $8\sim13%$ of all mediastinal tumors. This tumor is incidentally detected by routine chest roentgengography, but pericardial perforation or pleural effusion occurs rarely. In our patient cardiac tamponade was developed due to anterior chest wall contusion, we confirmed the anterior mediastinal tumor. Vital signs were stabilized after the pericardiocentesis, and the patient underwent the tumor resection in the anterior mediastinum for a definite treatment. On histologic examination, the tumor revealed cystic structures composed of mature squamous epithelium, pilosebaceous glands, mature fat tissue, gastrointestinal mucosa, respiratory epithelium, and pancreatic tissues.