• Title/Summary/Keyword: 기형도

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Expression of Morphogenic Protein Genes in Juvenile Red Spotted Grouper (Epinephelus akaara) with Deformity (붉바리(Epinephelus akaara) 기형 발생 치어의 형태형성 유전자 발현)

  • You, Jin Ho;Mun, Seong Hee;Oh, Hyeon Ji;Baek, Hea Ja;Lee, Young-Don;Lee, Chi Hoon;Kwon, Joon Yeong
    • Journal of Marine Life Science
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    • v.4 no.1
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    • pp.38-43
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    • 2019
  • The deformity occurring at the early developmental stage of red spotted grouper (Epinephelus akaara) causes detrimental effects on the process of juvenile production. In this study, we have compared the expressions of several key genes (insulin like growth factor 1: IGF-1, bone morphogenic protein 4: BMP4, peroxisome proliferator-activated receptors γ: PPARγ, matrix Gla protein: MGP) for morphogenesis between normal and 2 types (cephalic and jaw) of deformed juvenile fish. Expression of these genes were investigated in the brain, liver and muscle of each group of fish (n=20) by real-time PCR. Expression of IGF-1 and BMP4 mRNA in the brain and liver showed significant difference between normal and deformed fish (p<0.05). However, no difference was observed in the expression of PPARγ and MGP mRNA between normal and deformed fish in any tissues. It seems certain that IGF-1 and BMP4 are associated with the state of deformity in juvenile red spotted grouper.

Congenital Cardiac Anomaly Combined with the VATER Association - A case report - (VATER 증후군에 동반된 선천성 심장기형 치험 1례)

  • Ban, Dong-Gyu;Kim, Hyuck;Jee, Heng-Ok;Chung, Won-Sang;Kang, Jung-Ho;Kim, Young-Hak;Lee, Chul-Bum;Ham, Shi-Young;Kim, Nam-Su
    • Journal of Chest Surgery
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    • v.34 no.11
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    • pp.858-860
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    • 2001
  • VATER is a complex anomaly of multiple organs and often combined with cardiac anomalies. However, it can be cured with active surgical intervention. We achieved successful result with aggressive surgery in the patient with VATER and report it with references.

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Double Pulmonary Artery Sling with Multiorgan Abnormalities (다장기 기형을 동반한 이중 폐동맥 슬링)

  • Kang, Min-Woong;Na, Myung-Hoon;Lim, Seung-Pyung;Lee, Young;Kil, Hong-Ryang;Yu, Jae-Hyeon
    • Journal of Chest Surgery
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    • v.40 no.11
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    • pp.777-781
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    • 2007
  • Pulmonary artery sling is a rare congenital condition in which the left pulmonary artery arises from the right pulmonary artery forming a sling around the trachea. This causes tracheal compression with the resulting respiratory symptoms. Most cases are associated with cardiovascular and tracheobronchial abnormalities. Some cases present incidentally without respiratory symptoms in adolescents and adults. We report a case with double left aberrant pulmonary artery associated with multiorgan anomalies which was incidentally found.

Benign Mediastinal Cystic Teratoma Complicated by Cardiac Tamponade due to Trauma (외상에 의하여 심장눌림증을 유발한 종격동 양성낭기형종)

  • Choe Ju-Won;Kim Yong-In
    • Journal of Chest Surgery
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    • v.39 no.9 s.266
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    • pp.729-732
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    • 2006
  • Mediastinal teratoma is one of the most common lesions found in the anterior mediastinum, accounting for $8\sim13%$ of all mediastinal tumors. This tumor is incidentally detected by routine chest roentgengography, but pericardial perforation or pleural effusion occurs rarely. In our patient cardiac tamponade was developed due to anterior chest wall contusion, we confirmed the anterior mediastinal tumor. Vital signs were stabilized after the pericardiocentesis, and the patient underwent the tumor resection in the anterior mediastinum for a definite treatment. On histologic examination, the tumor revealed cystic structures composed of mature squamous epithelium, pilosebaceous glands, mature fat tissue, gastrointestinal mucosa, respiratory epithelium, and pancreatic tissues.

Esophageal Plexiform Schwannoma -A case report- (식도 얼기형 신경집종 -1예 보고-)

  • Jang, Jae-Seok;Park, Ki-Sung
    • Journal of Chest Surgery
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    • v.39 no.11 s.268
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    • pp.875-878
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    • 2006
  • A 39-year-old man presented with a esophageal submucosal tumor on regular check up examination. Preoperative exams showed the typical submucosal tumor as leiomyoma and operative procedure was enucleation for complete resection. Postoperative pathologic diagnosis including histologic and immunohistochemical study was compatible with plexiform schwannoma. Plexiform schwannoma is one of the least common variant of schwannoma that typically shows a plexiform or multinodular pattern. To our knowledge, there is rare case report of plexiform schwannoma originating in the esophagus and we report ore case with related literature.

Post-traumatic reconstruction of skeletal Class II malocclusion with multiple teeth fracture (외상과 다수의 치아 파절을 동반한 골격성 II 급 부정교합 환자의 치험례)

  • Jang, Woowon;Baek, Eui Seon;Hwang, Soonshin;Kim, Kyung-Ho;Chung, Chooryung J.
    • Korean Journal of Cleft Lip And Palate
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    • v.20 no.1
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    • pp.49-58
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    • 2017
  • We report the rehabilitation of Class II malocclusion with multiple teeth fracture due to trauma. A multidisciplinary team approach was necessary to treat patient's problems such as bone fracture, malocclusion, and multiple teeth fracture. Emergency conservative treatment, orthodontic treatment and prosthetic restoration successfully restored the occlusion. However, special considerations were needed along the orthodontic treatment process due to the unexpected complications such as ankylosis, root resorption and detection of additional teeth fractures.

Coexistence of the Absence of the Left Common Carotid Artery, a Common Origin of the Left External Carotid Artery and the Right Common Carotid Artery, and an Aberrant Right Subclavian Artery: A Case Report (좌경동맥 결손, 좌외경동맥과 우경동맥 공통줄기 기형 및 이상 우쇄골하동맥의 동반 발생: 증례 보고)

  • Soo Jeong Lee;Hye Jeong Choi;Sang Heum Kim
    • Journal of the Korean Society of Radiology
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    • v.82 no.4
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    • pp.948-952
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    • 2021
  • The absence of the common carotid artery (CCA) and the common origin of the left external carotid artery (ECA) and the right CCA are rare anomalies of the cervical vascular system. We report here a case involving the coexistence of these vascular anomalies with an aberrant right subclavian artery, which is a common congenital anomaly in the aortic arch, and review the embryologic mechanism and clinical importance of this case.

Experimental Study for the Teratogenic Effect of Gamma-ray on the Heart of Chick Embryo (계태에서 감마선 조사에 의한 심장기형 발생에 관한 실험적 연구)

  • Jo, Yong Whan;Kim, Nam Su;Moon, Sung Yup;Yum, Myeng Gul;Kim, Sung Hoon;Chun, Ha Chung;Kim, Yong Joo;Lee, Hahng
    • Clinical and Experimental Pediatrics
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    • v.46 no.6
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    • pp.554-560
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    • 2003
  • Purpose : To investigate the teratogenic effect of gamma-ray on the heart of chick embryo. Methods : 50 rad, 100 rad, 150 rad, 200 rad, 250 rad, and 300 rad of gamma-ray were used to irradiate three days old chick embryos. The control group was not irradiated. After three weeks, the embryos were sacrificed and examined for cardiovascular malformation. Results : The survival rate of the gamma-ray irradiated group was significantly lower than that of the control group(33.3-63.3% vs 76.4%, P=0.001). The cardiac malformation rate of the experimental group was 11.0%. In the control group, no congenital cardiac malformations were observed. The experimental groups had a significantly higher malformation rate(P=0.001). The types of malformation were ventricular septal defect, tricuspid atresia, Ebstein anomaly and aortic arch anomaly. In the gamma-ray irradiated group, the cardiac malformations were : 14 small ventricular septal defects (VSDs), five large VSDs, two tricuspid atresias, and one Ebstein anomaly. The higher the dose of radiation applied, the higher the incidence of cardiac malformation was noted. Conclusion : Gamma-ray irradiation of 3 days old chick embryos increased the rate of death and the rate of cardiac malformation significantly.

혈관내 Alcohol 주입법에 의한 두경부 정맥 기형증의 치험 2례

  • Kim, Hyeong-Gon;Park, Gwang-Ho;Lee, Ui-Ung;Kim, Jun-Bae;Ju, Jae-Dong;Kim, Dong-Ik
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.13 no.4
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    • pp.444-449
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    • 1991
  • 저자등은 5세 여아의 좌측 하순부에 발생한 정맥기형증 및 25세 여자 환자의 좌측 교근부에 발생한 정맥 기형증에 대하여 비와과적 방법인 직접알콜 주입에 의한 sclerosing therapy 치료한 결과, 별다른 후유증이나 재발의 소견없이 심미적, 기능적으로 양호한 결과를 얻었기에, 과거 sclerosing solution의 단점을 보완한 순수한 알콜제재의 사용을 문헌고찰과 함께 보고하는 바이다.

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