• Progress in Medical Physics
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• v.21 no.1
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• pp.42-51
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• 2010

Imaging studies using MRI, PET, and/or MEG have been primary evaluation methods to quantitatively assess cognitive function. Recent advances in computational technology and information technology may allow a novel evaluation methodology to quantitate cognitive function more cost-effectively. In this study, we developed a software package composed of a series of tests to evaluate cognitive ability combined with a user-friendly touch screen input device. This cognitive assessment tool can quantitate concentration, numeric memory, associative memory, topological memory, visual and muscular reaction, and acoustic reaction over a relatively short testing time. We performed an empirical study on eighty normal subjects aged 20 and 59 years old using the developed evaluation methods. Age-related cognitive deterioration after 40 years old was confirmed. There was no difference in cognitive ability between male and female in the same age group. This study demonstrates the feasibility of a simple but effective evaluation software tool to quantitatively assess cognitive ability. This methodology may provide improved accessibility and reduced costs to perform cognitive function studies to compare between various subject groups.

• The Journal of Korean Association of Computer Education
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• v.14 no.5
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• pp.39-46
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• 2011

Serious games are designed for special purposes of education, training, treatment as well as game-like fun and entertainment. Recently, domestic and foreign market of serious game are growing rapidly. By dissemination of smartphone, the global market for serious game will be expanded for various purposes and users. In this paper, we design and implement serious game 'QUICK REMEMBER 20' for memory improvement using smartphone. We analyze game users based on socio-demographic characteristics and evaluate the learning effectiveness of this game with statistic method.

• Proceedings of the ESK Conference
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• 2004.10a
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• pp.18-18
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• 2004

• Therapeutic Science for Rehabilitation
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• v.4 no.2
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• pp.73-83
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• 2015

Objective: The purpose of this study was to examine the effect of the Spaced Retrieval Training (SRT) with Errorless learning on the elderly with Mild Cognitive Impairment (MCI)'s memory, Instrumental Activities Daily Living, Depression symptom. Methods: A single subject experimental research with ABA design was conducted in this study on the 78-years-old person who was enrolled in day-care center. The total experimental sessions were 16 which composed of 3 sessions for baseline, 10 sessions for intervention and 3 sessions for second baseline. K-Auditory Verbal Learning Test (K-AVLT) was measured for the memory each session. For the measurement of cognitive function, IADL, depression Symptom, Korean version of Montreal Cognitive Assessment (MoCA-K), Philadelphia Geriatric Center Instrumental Activities Daily Living (PGC IADL), Geriatric Depression Scale Korean Version (GDS-K) was measured at pre-post test. Results: Memory at the phase B was improved than Phase A. At the phase B, the scores trend was ascending, but after the intervention at the phase A', the scores trend was descending. The scores of MoCA-K were improved, PGC IADL were maintained, GDS-K were decreased. Conclusion: This results support the evidence of the SRT with EL on the elderly with MCI in the clinical setting. In the future, the correlation researches about MCI's memory and other functional factors will be needed for effective occupational therapy service.

• Journal of the Korean Society of Food Science and Nutrition
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• v.42 no.8
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• pp.1190-1196
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• 2013

The purpose of this study was to investigate the mechanism and effects of different types of ginseng on memory improvement in an experimental rat model. In this study, SD rats were induced for memory deficits through scopolamine treatment (1 mg/kg, i.p.) then administrated with ginseng extract for 7 weeks. The rats were divided into five groups: saline (1 mL/kg, NC: negative control), white ginseng (300 mg/kg, WG), red ginseng (300 mg/kg, RG), black ginseng (300 mg/kg, BG), and scopolamine (1 mg/kg, PC: positive control). The step through latency of the BG and RG groups was significantly longer than the PC group in the retention trial of multiple trial passive avoidance test. In the spatial reference memory triads of the Morris water maze test, the latency time of BG and RG was significantly lower than the PC group. In addition, in the prove test, the time spent in the platform quadrant of BG and RG groups were significantly longer than the PC group. Brain choline acetyltransferase (ChAT) activities BG and RG groups significantly increased compared to other groups. On the other hand, the levels of malondialdehyde (MDA) were significantly lower in the BG and RG groups compared to other groups. These result suggested that black ginseng could be useful to enhance learning memory and cognitive function by regulation of cholinergic enzymes.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.1
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• pp.477-486
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• 2020

This study was undertaken to analyze the correlation between depression and memory, by considering the occurrence of ApoE ɛ4 and clinical dementia rating in the elderly with Alzheimer's dementia. This study included 50 participants over 65 years of age, evaluated with CDR 0.5 to 2. We performed CDR, SVLT-E, RCFT, SGDS-K, and ApoE genotyping. Spearman's correlation analysis was used for determining the correlation between depression and memory. The results indicate a significant negative correlation between depression and immediate recall verbal memory in the CDR 1 and 2 without ApoE ɛ4 carrier group (p<0.05). Furthermore, a significant negative correlation was also determined between depression and delayed recall verbal memory in the CDR 1 of the same group. Ed. Notes: The previous sentence already shows this correlation. I suggest this should be deleted from this statement. However, no significant correlation was observed between depression and visual memory. This study found a significant correlation between depression and immediate recall verbal memory. Also, the presence of ApoE ɛ4 indicates a significant correlation between depression and delayed verbal recall memory. Taken together, our results indicate that verbal memory training rather than visual memory training can be more effective in early AD. Also, the treatment of depression will provide a complementary effect.

• 한국노년학
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• v.39 no.4
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• pp.801-824
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• 2019

As becoming an aging society, there is a rising interest on dementia. But Dementia prevention program, executed at the national level, is in insufficient state. In this study, to design and diffuse Dementia prevention program, this study conduct Cognition improvement program and evaluate cognitive function in aspects of Discrimination, Organization, Thinking, Memorizing, and Concentration capacity. So that this study try to investigate how this Cognition improvement program will affect in detail to cognitive function in senior people. This study designed Silver Cognition program for 5 aspects of cognitive function; Discrimination, Organization, Thinking, and Concentration capacity. And this studyrecruited experimental group with control group, and conducted the program to them for 3 months. At the start and the end of the program, this study evaluated their MMSE-DS score, Geriatric depression scale, Quality of life score, and cognitive function test score by survey. Finally, this study compared and analyzed these first and second score to find the effects of this program to cognitive function. As the results compared between first and second score of MMSE-DS test, Geriatric depression scale, Quality of life scale, and cognitive function test, Silver Cognition program has a significant effects to improve cognitive function, MMSE-DS score and Geriatric depression scale. As the results of the test on cognitive function in 5 aspects, cognitive function is more improved in the order of Memorizing, Thinking, Concentration, Discrimination, and Organization capacity. After the Silver Cognition program, Memorizing and Thinking capacity have most improvement. But aging of brain function is faster in these two capacity, so if more concentrated education is conducted for these two capacity, then it will bring better effects for prevention of dementia.

• Journal of Yeungnam Medical Science
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• v.27 no.1
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• pp.27-36
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• 2010

Purpose : The purpose of this study was to find out cognitive function of the patients with subjective memory complaint. Material and Methods : From March 1st 2005 to May 31st 2009, 155 normal individuals without any medical illness who visited Yeungnam University Hospital to undergo medical checkup with neurocognitive test was enrolled, and checked by using Cognitive Assessment & Reference Diagnostic System. Results : 107 of the patients had normal cognitive function, 21 patients (about 15%) were diagnosed with dementia, and 10 patients (about 7%) were diagnosed with considerable psychiatric illness, such as depression, anxiety disorder, adjustment disorder. In amnesia, agnosia, aphasia, attention, calculation, dysexecution, Dementia group and Psychiatric illness group has worse score than Normal individuals group. But, in apraxia, Dementia group has worse score than Psychiatric illness group and Normal individual group. Conclusion : Because the patients with subjective memory complaint can be diagnosed as any psychiatric illness as well as dementia, sensitive screening test and early psychiatric approach is needed.

• Proceedings of the Korean Society of Computer Information Conference
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• 2017.01a
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• pp.173-174
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• 2017

본 논문에서는 노화에 의해서 떨어지는 기억력의 저하 뿐 만 아니라 뇌의 비가역적 질환인 치매의 예방을 위하여 기억력 저하에 도움을 줄 수 있는 앱의 개발을 위하여 뇌의 각 영역별 기능이 활성화 될 수 있도록 하는 훈련이 가능할 수 있도록 앱을 설계하고자 한다.

• 가정의 벗
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• v.36 no.4 s.416
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• pp.24-25
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• 2003