• Title/Summary/Keyword: 근친도

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Mating Systems and Inbreeding Pressure in Populations of Wild Lentil Tare, Vicia tetrasperm (Leguminosae) (얼치기완두(콩과) 집단의 교배계와 내교잡 압력)

  • Huh, Man-Kyu
    • Journal of Life Science
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    • v.17 no.11
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    • pp.1477-1481
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    • 2007
  • The mating systems of natural populations of Vicia tetrasperm in Korea were determined using allozyme analysis. The result suggests that V. tetrasperm is low rates of outcrossing or mix-mating outcrossing (self-fertilization, s < 0.5). At the population levels, the values of inbreeding coefficient of ten populations in Korea varied from 0.131 to 0.176, giving an average 0.154. For ten natural populations, multi-locus estimates of outcrossing (tm) was 0.333 across fifteen polymorphic loci, with individual population values ranging from 0.269 to 0.423. The differences between the tm and ts values were not close to zero (tm - ts > 0.154), indicating that biparental inbreeding was significant in the loci. The reason for relatively low outcrossing rates of some populations could be attributed to extensive consanguineous mating and isolation of flowering mature plants. Although heterozygote excess was observed in one natural population, most populations exhibited varying degrees of inbreeding and heterozygotes deficit. Thus, selection against homozygotes operated in the progeny populations throughout the life cycle.

Identification of Homozygous Mutations in Two Consanguineous Families with Hearing Loss (청력 장애를 나타내는 두 근친 가계로부터 동형접합성 돌연변이의 분리)

  • Lim, Si On;Park, Hye Ri;Jung, Na Young;Park, Cho Eun;Kanwal, Sumaira;Chung, Ki Wha
    • Journal of Life Science
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    • v.31 no.5
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    • pp.453-463
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    • 2021
  • Hearing loss is a group of clinically and genetically heterogeneous disorders characterized by congenital- to adult-onset deafness with frequent additional symptoms such as myopathy, nephropathy, and optic disorders. It is commonly divided into two types: syndromic, with no other symptoms, and nonsyndromic, with other symptoms. Autosomal recessive hearing loss is relatively frequent in Pakistan, which may be due in part to frequent consanguineous marriages. This study was performed by whole exome sequencing to determine the genetic causes in two Pakistani consanguineous families with autosomal recessive hearing loss. We identified a pathogenic homozygous variant (p.Leu326Gln in MYO7A) in a family with prelingual-onset hearing loss and two variants of uncertain significance (p.Val3094Ile in GPR98 and p.Asp56Gly in PLA2G6) in a family with early-onset hearing loss concurrent with muscular atrophy. The missense mutations in MYO7A and PLA2G6 were located in the highly conserved sites, and in silico analyses predicted pathogenicity, while the GPR98 mutation was located in the less conserved site, and most in silico analysis programs predicted its nonpathogenic effect. Homozygosity mapping showed that both alleles of the homozygous mutations identified in each family originated from a single founder; spread from this single source might be due to consanguineous marriages. This study will help provide exact molecular diagnosis and treatment for autosomal recessive hearing loss patients in Pakistan.

재래산양의 정액동결보존 기술과 인공수정에 관한 연구

  • 최창용;조숙현;이명식;최성복;최순호;손삼규
    • Proceedings of the KSAR Conference
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    • 2002.06a
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    • pp.31-31
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    • 2002
  • 건강보조식품의 홍수와 함께 우유보다 소화흡수가 좋고 건강식을 즐겨하는 현대인들의 취향에 발맞추어 상대적으로 유량과 산육성이 좋은 외래산양의 유입이 급속하게 늘어남으로써, 일부 재래산양 사양 농가들은 생산성 향상을 목적으로 재래산양과 외래산양의 무분별한 교배를 시키므로써 재래산양의 유전자원의 보존문제가 대두됨과 동시에 재래산양의 개량의가속화, 근친교배에 따른 문제점, 계절번식에 따른 산자생산의 한계 등은 재래산양의 인공수정에 대한 깊이 있는 연구로 이어져야 하겠기에 본 연구에서는 38 두의 재래산양을 공시하여 실험한 결과 여름과 겨울에 채정한 정액보다는 봄가을에 채정한 정액의 량이 2.0㎖로 여름과 겨울보다 많았으며, 정자농도는 봄에 21.0×10/sup 8//㎖로 가장 짙었고, 총정자수는 봄에 42.0×10/sup 8/로 가장 많았으며, 운동성은 가을에 90(motility)로 가장 좋았다. (중략)

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Studies on the Mating System in Shiitake, Lentinus edodes (Berk.) Sing (표고버섯의 교배계(交配系)에 관한 연구(硏究))

  • Park, Yong-Hwan
    • The Korean Journal of Mycology
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    • v.2 no.1
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    • pp.31-33
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    • 1974
  • The four stocks of Lentinus edodes (Berk.) SING.-1-3, 16-3, 5NG2, 5NG3 were used as mating materials. As a result of full stock mating pattern for four stocks, all of mating types formed clamp connection but degrees of formation of clamp connection and period required for the formation were somewhat different among all of the mating types. In the mating of two New Guinean stocks-5NG2, 5NG3-, the mycelial growth and the formation of clamp connection was comparatively reduced.

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Comparison of Genetic Responses Using Reproductive Techniques of MOET and In Vitro Fertilization in Cattle Populations (다배란과 수정란이식 및 체외수정기술을 이용한 소의 유전적 개량량 비교)

  • 전광주
    • Journal of Embryo Transfer
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    • v.11 no.1
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    • pp.1-6
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    • 1996
  • 다배란 수정란이식(MOET)과 체외수정(IVF)기술을 이용한 육종체계에서 예상되는 유전적 개량량을 여러 집단의 크기에서 비교한 결과 체외수정기술이 MOET육종기술보다 특히 개량대상 유전력이 낮을때 훨씬 효율적으로 나타났다. 그러나 유전력이 높아지면 (h$^2$=0.3, 0.5), MOET와 IVF간의 상대적 차이는 미진하게 나타났다. 체외수정을 이용한 육종기술에서 암컷의 선발 강도는 대단히 높일 수 있는 반면 난자의 회수율이 많을수록 상대적으로 수컷에 대한 선발 강도는 낮아진다. 그 이유는 한 가계에서 근친을 피하기 위해 한 마리의 수컷만 선발해야 하므로 수소의 선발강도는 난자의 회수율이 높을수록 상대적으로 낮아진다. 여러 수준의 난자회수율(10, 20, 30, 50, 100)중에서 30일 때 가장 높은 유전적 개량을 나타내었다. (Key word: MOET, IVF,selection responses)

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Analysis on the Sexual Expression in related to Children's Social Development (<만화로 보는 그리스 로마 신화> 속 아동의 사회학습과 연관된 만화의 윤리적 표현 분석)

  • Park, Keong-Cheol;Jung, Sun-Jin;Jeong, Sun-Mee
    • Cartoon and Animation Studies
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    • s.30
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    • pp.113-137
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    • 2013
  • The accessibility and effect of cartoon on children are very significant. Since cartoon is a medium of conveying information through text and pictures, it has a characteristic of being easily approached by children than any other medium. Its accessibility to children is inevitably more exceptional than any other medium in the sense that it is a method of not only telling or reading stories but also showing stories. The main audience of is children. It has a characteristic of being easily accepted by children since it's mythology seen in cartoon than read in text. However, gods conducts are full of unethical expressions. Sexual expressions of intermarriages between mother and son, between brother and sister and between uncle and niece, as well as extramarital intercourse are very unethical that could have negative effects on children. This study analyzed the unethical expressions of gods that could have negative effects on children at current point in time. Zeus was often unfaithful to his wife with many stories about the children of Zeus that were created from extramarital intercourse. Standard of value on rational decision has been established for adult readers, but children can readily accept things since they lack their own rational decision on what's right and wrong. As an alternative to children's uncritical observatory study, there is a need for author's intervention to help children form desirable values. The purpose of this study is to analyze the sexual expressions of Zeus and gods in that could affect children's social study.

The Situation of Genetic Exchange in Duroc Breed and Impacts on Genetic Evaluation (국내 듀록의 종돈장간의 교류현황과 유전능력평가에 미치는 효과)

  • Seo, Jae-Ho;Shin, Ji-Seob;Noh, Jae-Kwang;Song, Chi-Eun;Do, Chang-Hee
    • Journal of Animal Science and Technology
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    • v.53 no.5
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    • pp.397-408
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    • 2011
  • The study was carried to identify the impact on nation-wide genetic evaluation and to obtain basic materials for the development of strategies in Swine Improvement Network Project (SINP). Data consisted of pedigree records of 235,511 and performance records of 70,747 for Duroc from 1987 to 2010 were collected by Korea Animal Improvement Association. Performance traits included three point back fat thickness (Shoulder, Belly, Waist), loin area, days to 90 kg and average daily gain. Exchange of genetic resources cross the breeding farms was not high, and furthermore the sizable farms which can accommodate genetic evaluation within the farm were scarce. Three data sets (individual farm evaluation: I, two sub-group evaluation: S, and whole eight farm evaluation: P) were used for genetic analysis. Genetic variances were larger in subordinate farms than in joiners farms for connectedness, and consequently the heritabilities were generally higher in subordinate farms than in joiner farms with I. The standard errors of heritability were small in the order of I, S and P. Estimated average inbreeding coefficients were 1.12%, 0.95% and 1.53% for joiner and subordinate group with S and population with P, respectively. The estimated correlations of breeding values with I and P were lowest. The correlations of breeding values with I and P for traits ranged 0.22 to 0.45 for moved parent animals and 0.24 to 0.72 for all animals. The results in the study suggest that nation-wide evaluation uses more pedigree information and improves accuracy. Furthermore SINP for connectedness could help to improve the accuracy of evaluation.

Genetic variation in populations of the Korean endemic Eranthis byunsanensis (Ranunculaceae) (한국 특산식물 변산바람꽃(Eranthis byunsanensis)의 유전적 변이)

  • So, Soonku;Lee, Byongsoon;Park, Ki-Ryong
    • Korean Journal of Plant Taxonomy
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    • v.42 no.4
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    • pp.253-259
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    • 2012
  • The genetic variation in populations of Eranthis byunsanensis, an endemic and rare species of Korea, was studied using starch gel electrophoresis. All five known populations were sampled for allozyme electrophoresis of nine enzymes coded by 10 loci. The overall genetic variation of E. byunsanensis population was shown to be considerably high within the populations (A = 2.4, P = 90.0, $H_E$ = 0.311). A positive $F_{IS}$ value of E. byunsanensis indicated an overall deficiency of heterozygotes, and a low $F_{ST}$ value (0.131) showed little differentiation among populations. The high genetic variation, less genetic differentiation among populations, and a significant amount of heterozygote deficiency propose the hypothesis that they have an experience of recent isolation and fragmentation of their habitat. Thus, the rate of gene flow has been drastically reduced, and the rate of inbreeding in E. byunsanensis populations has increased. Current habitats in Mai-san and Naro-do are vulnerable due to their small population size and the levels of anthropogenic activity in the region constantly threatening survival of this species. Because of the high genetic variation and low levels of differentiation among populations in E. byunsanensis, it is not issue which populations have a priority for protection, but we may concern the plan to maintain population continuously and diminish the rate of inbreeding.

Rewriting Race in Hopkins's Of One Blood; Or, the Hidden Self: "the Hidden Self," Past/Memory, Incest, and Black Female Body (홉킨스의 인종 다시쓰기-"숨겨진 자아,"과거/기억, 근친상간, 그리고 흑인여성의 몸)

  • Kang, Hee
    • Journal of English Language & Literature
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    • v.54 no.2
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    • pp.301-322
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    • 2008
  • Pauline Hopkins's Of One Blood; Or, the Hidden Self was published in the Colored American Magazine during 1902-03. As a literary experimentalist and a political protester, Hopkins uses her fiction as a medium to overcome and ameliorate the violently racialized surroundings of the turn-of-the-century America. Having been faced with racist rhetorics and theories growing on biological differences between races, Hopkins must have felt an overwhelming urgency to challenge the heritage of slavery in American history. In order to speak out her political agenda in such a milieu, she needed a new setting as well as new narrative materials for the new era. She had to move the setting from America to Africa, the ancient utopian Ethiopia; her interest in the ancient African civilization reflects both a popular African-American vision of Africa and the movement of "black nationalism" of the time. She also needed materials from nineteenthcentury sciences, the newly evolving theories of psychology and mysticism (spiritualism/mesmerism), to explore the meaning of "the hidden self" which unfolds the complex nature of Hopkin's position on race, "blood," and African-American racial subjectivity. Hopkins in the novel explores not the color line but the bloodline. Tracing the horrific legacy of incest in the history of slavery, she attempts to redefine the true racial identity of African-Americans in America and to reconstruct their past, both family and race history. At the very center of her major tropes in the novel-such as "of one blood," "the hidden self," and incest-exists female body. Black female body, though it represents the violent site of sexual body (rape and incest) in slavery, ultimately becomes a vehicle to convey and preserve the truth of racial memory/past/history for African-Americans. As a conveyor of the past, black women not just connect the past and the present but also reawaken AfricanAmericans with the legacy of the African 'pure' bloodline. Hopkins's vision here necessitates the reevaluation of black women's role in family and history, heralding the 20th-century black feminine writing. With the major tropes, Hopkins clearly suggests that the blood of (African-)Americans is unrecognizably intermixed. Although the novel ends with ambivalence and without resolution on what Africa signifies, those tropes certainly offer her a vehicle for criticizing as well as for challenging the racial reality of America.

A Study of Ecological Design Strategies Around National Parks - A Case of Moodeungsan National Park in Korea - (국립공원 주변지역의 생태디자인 적용방안 연구 - 무등산 국립공원을 중심으로 -)

  • Jeong, Kyongyeon;Byun, Byungseol
    • Journal of Wetlands Research
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    • v.18 no.1
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    • pp.1-9
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    • 2016
  • Areas around of National Park have been severed eco-corridor of wildlife due to urban expansion and development. Habitats have been fragmented into small pieces. Habitat fragmentation reduces the biodiversity of organisms because the exchange loss and inbreeding of wild fauna and flora. The main cause of the fragmentation of ecological networks in areas around of Moodeungsan National Park are are that the cemetery, cutting of mountain, roads, public parking lots, mountain encroachment by land, urban infrastructure, electric transmission towers, urban area. Area around of National Park must be equipped with ecological networks through an ecological design that can communicate with each other in the national park and urban areas.