• 대한골관절종양학회지
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• 제1권1호
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• pp.98-104
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• 1995

장기간 피부에 존재하는 궤양성 반흔이나, 만성골 수염의 누루 등에서 편평상피 세포암이 잘 발생하며 이들은 동통이 더욱 심해지거나 종괴의 크기가 갑자기 증가할때 그리고 분비물(discharge)이 늘어 날때는 악성 변화를 의심하여야 하며 조기에 생검을 하여 진단 후 적절한 수술적 치료가 필요하다. 또한 이들은 국소 림프절로의 전이가 빈발하므로 Grade II와 III에서는 예방적으로 국소 림프절에 방사선 조사(irradiation)를 고려해야 된다.

• 대한골관절종양학회지
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• 제14권2호
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• pp.172-177
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• 2008

유상피 육종은 젊은 남자 또는 청소년에 호발하는 매우 드문 고등급의 연부조직 육종이며, 수부, 전완부, 하퇴부, 족부에 호발한다. 대부분의 경우 육종은 천천히 자라고, 진피층이나 심부의 연부조직에서 발생하며 원위사지부의 심부 연부조직에 주로 발생한다. 유상피 육종은 국소 재발이나 림프절 전이를 잘하며, 양성 또는 악성의 성질을 가지고 있어 진단에 어려움이 있다. 치료로는 광범위 절제술, 방사선 치료 및 화학요법 등이 시행되어 진다. 저자들은 드문 연부조직 육종인 유상피 육종의 례를 경험하고 이를 보고하는 바이다.

• 한국응용약물학회:학술대회논문집
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• 한국응용약물학회 1994년도 춘계학술대회 and 제3회 신약개발 연구발표회
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• pp.232-232
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• 1994

인삼이 면역계 질환의 일종인 과민성 반응에 대한 치료약으로서의 가능성을 연구하기 위해서 in viva와 in vitra실험을 수행하였다. in vitra실험으로서는 hyaluronidase의 활성을 지표로 삼았으며, in viva실험에서는 mouse이각, rat등피부, 복강 비만세포, 그리고 guinea pig의 ileum에서 면역반응에 대한 아답타겐의 작용을 관찰하였다. in uitra 실험에서는 hyaluronidase와 histamine 분비를 항알레르기 작용의 지표로 사용하였다. hyaluronidase의 경우 그 활성은 Cacl2로 활성화 시키기 전이나 후에 모두 아답타겐(100, 50, 및 10 mg/ml)에 의해서 현저하게 억제되었다. 한편 rat 복강 비만 세포에서의 histamine유리 시험에서는 아답타겐(0.5, 1, 5mg/ml)이 histamine유리가 증가되었다. Guinea pig의 ileum 평활근에서는 아답타겐이 평활근 자극 작용없이 항히스타민 효과률 나타내었다. in uiua 실험의 첫 단계로 우리는 혈관 투과성에 미치는 아답타겐의 효과를 mouse 이각과 rat 등피부에서 관찰하였다. Mouse이각에서의 실험에서는 hoistamine, serotonin, 그리고 LTC4로 challenge하여 관찰한 결과 histamine과 serotonin의 경우, 혈관투과성 항진은 아답타겐(50-400mg/m1)에 의해서 유의성있게 억제되었으나, rat 등 피부에서는 mouse에서와는 달리 48-hr PCA가 증가 되었고, histamine에 의한 혈관투과성 항진은 아답타겐에 의해 영향을 받지 않았다. 반면에 compound 48/80과 serotonin에 의한 혈관투과성 항진은 mouse 의 경우에서처럼 아답타겐에 의해 억제되었다.

• 대한세포병리학회지
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• 제8권2호
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• pp.185-189
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• 1997

A sex cord tumor with annnular tubules is a relatively rare ovarian neoplasm. The cytologic findings from a fine needle aspiration biopsy of neck metastasis of a sex cord tumor with annnular tubules are described. The origin of the neck metastasis was the right ovary, and the tumor was diagnosed six years ago. The cytologic findings were characterized by tumor cells arranged in solid or follicular patterns. The tumor cells formed rosette-like or complex tubular structures with central rounded or coalesced hyaline materials. It was difficult to distinguish this tumor cytologically from granulosa cell tumor, thyroid follicular neoplasm, Sertoli-Leydig cell tumor, and Brenner tumor, but complex tubular structures were helpful in discriminating between these tumors.

• 한국재료학회지
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• 제12권6호
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• pp.431-435
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• 2002

The dark current and photocurrent(PC) spectrum of Mg-doped GaN thin film were investigated with various bias voltages and temperatures. At high temperature and small bias, the dark current is dominated by holes thermally activated from an acceptor level Al located at about 0.16 eV above the valence band maximum $(E_v)$, The PC peak originates from the electron transition from deep level A2 located at about 0.34 eV above the $E_v$ to the conduction band minimum $(E_ C)$. However, at a large bias voltage, holes thermally activated from A2 to Al experience the field-in-duces tunneling to form one-dimensional defect band at Al, which determines the dark current. The PC peak associated with the transition from Al to $E_ C$ is also observed at large bias voltages owing to the extended recombination lifetime of holes by the tunneling. In the near infrared region, a strong PC peak at 1.20 eV appears due to the hole transition from deep donor/acceptor level to the valence band.

• Tuberculosis and Respiratory Diseases
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• 제71권2호
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• pp.139-143
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• 2011

Small bowel metastasis of pleomorphic carcinoma of the lung is very rare. A 58-year-old man was admitted to our hospital with abdominal palpable mass in the right upper quadrant area. He underwent right middle and lower lobectomy for early stage pleomorphic carcinoma of the lung approximately 3 months ago. USG-guided biopsy was performed for abdominal mass. Pathologic examination revealed a metastatic pleomorphic carcinoma from the lung. He received chemotherapy followed by radiation therapy but died due to septic shock caused by intestinal stenosis and adhesion. We report the first case of small bowel metastasis by pleomorphic carcinoma of the lung after curative surgery.

• 대한기계학회논문집A
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• 제26권9호
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• pp.1923-1930
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• 2002

In this paper, we present modeling and simulation of microlens formation by means of a deep X-ray lithography followed by a thermal treatment of a PMMA (Polymethylmethacrylate) sheet. According to this modeling, X-ray irradiation causes the decrease of molecular weight of PMMA, which in turn decreases the glass transition temperature and consequently causes a net volume increase during the thermal cycle resulting in a swollen microlens. In this modeling, the free volume theory including the relaxation process during the cooling process was considered. The simulation results indicate that the modeling in this study is able to predict the fabricated microlens shapes and the variation pattern of the maximum heights of microlens which depends on the conditions of the thermal treatment. The prediction model could be applied to optimization of microlens fabrication process and to designing a micro mold insert for micromolding processes.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2003년도 춘계학술대회 논문집
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• pp.228-232
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• 2003

Mircolens and microlens arrays are realized using a novel fabrication technology based on the exposure of a resist, usually PMMA, to deep X-rays and subsequent thermal treatment. Hot embossing process is also studied for mass production. The fabrication technology is very simple and produces microlenses and microlens arrays with good surface roughness of several nm. The molecular weight and glass transition temperature of PMMA is reduced when it is irradiated with deep X-rays. The microlenses were produced through the effects of volume change, surface tension. and reflow during thermal treatment of irradiated PMMA. A hot embossing machine is designed and manufactured with a servo motor transfer system. The hot embossing process follows the steps of heating mold to the desired temperature, embossing a mold insert on substrate. cooling mold to the de-embossing temperature. and de-embossing. Microlenses were produced with diameters ranging from 30 to 1500 ${\mu}{\textrm}{m}$. The surface X-ray mask is also fabricated to realize microlens arrays on PMMA sheet with a large area.

• 대한세포병리학회지
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• 제4권2호
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• pp.166-170
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• 1993

We describe the cytologic features of metastatic ameloblastoma which presented as multiple bilateral lung nodules. The patient was a 22-year-old male who had recurrent ameloblastoma of the mandible 7 years after the diagnosis of primary lesion. Fine needle aspiration of one of the pulmonary nodules revealed patchy arrangement of cell clusters with outer palisading columnar cells and inner irregular loose polygonal cells. Most of tumor cells had plenty cytoplasm and ovoid nuclei which lacked either pleomorphism or hyperchromatism. The cytologic findings corresponded with histologic features of the primary site which was also benign looking ameloblastoma.

• 대한핵의학회지
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• 제17권2호
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• pp.79-82
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• 1983

Traditionally, a positive bone scan shows single or multiple areas of increased uptake in the metastatic skeletal disease. The occurence of "cold" lytic-like or photon-deficient lesions in bone imaging is probably uncommon. Photon-deficient focus or cold lesion of the sternum was demonstrated on $^{99m}Tc-MDP$ bone imaging in 2 individuals with acute myloid leukemia and primary hepatoma, respectively.