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Age-Related Fecal Calprotectin Concentrations in Healthy Adults (건강한 성인의 연령별 분변 칼프로텍틴의 농도)

  • Park, Shin Young
    • Korean Journal of Clinical Laboratory Science
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    • v.52 no.3
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    • pp.181-187
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    • 2020
  • Fecal calprotectin (FC) is a marker used for the differential diagnosis of inflammatory bowel disease (IBD). FC is also used to determine the effects of treatment and recurrence prediction because of its non-decomposition by bacteria, relative week stability at room temperature, and its uniform distribution within feces. Healthy male and female adults between the age of 30 and 80 living in Jeju were selected for this study. The FC concentration in the healthy control group (N=45) was distributed widely as 0~545.9 ㎍/g and showed a significant difference with age in healthy adults. The FC concentration in adults over 70 years old (80.6 years on average) was 160.3 ㎍/g. The result is approximately 10 times higher than in adults below 50 years (44 years on average), with FC concentrations at 15.88 ㎍/g. Moreover, adults over 50 years, with an average age of 59.6, had FC concentrations of 35.46 ㎍/g, which were two times higher than the below 50-year-old group, confirming the significant correlation between age and FC concentration. As the FC test is a non-invasive and cost-effective objective marker in IBD tests, a suitable cut-off value is required for different ages. This study provides the baseline data for differential diagnoses.

Luminescence characteristics of bismuth and europium co-doped yttrium oxide red phosphor for white light emitting diodes (Bi와 Eu이 도핑된 yttrium oxide의 white LED용 적색 형광체 발광 특성)

  • Park, W.J.;Jung, M.K.;Yoon, S.G.;Yoon, D.H.
    • Journal of the Korean Crystal Growth and Crystal Technology
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    • v.16 no.3
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    • pp.112-115
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    • 2006
  • The red emission properties of $Bi^{3+}$ co-doped $Y_2O_3:Eu^{3+}$ prepared by the solid-state reaction was investigated, in order to verify its potential to act as the red emitting phosphor of white LEDs. The emission spectrum consisted of a weak band at 581, 587, 5931 and 599 nm, with maximum sharp peaks occurring at about 611 nm due to the $^5D_0{\rightarrow}^7F_2$ transition of $Eu^{3+}$, while the excitation spectrum exhibited a broad band between 290 and 430 mm with peaks occurring in the range of $310{\sim}390nm$. Also, SEM image of the sample containing 0.43 mol% $H_3BO_3$ and 2.08 mol% $BaCl_2{\cdot}2H_2O$ phosphor particles grew to achieve diameters of $700{\sim}800nm$.

B1+ Homogenizaion over Whole Field of View in High Field MRI (고자장 MRI에서의 영상 영역에 대한 B1+ 균질성)

  • Kim, Hong-Joon;Son, Hyeok-Woo;Cho, Young-Ki;Yoo, Hyoung-Suk
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.23 no.1
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    • pp.96-100
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    • 2012
  • In high static field magnetic resonance imaging(MRI) systems, $B_0$ fields of 7 T and 9.4 T, the impressed RF field shows larger inhomogeneity than in clinical MRI systems with B0 fields of 1.5 T and 3.0 T. In multi-channel RF coils, the magnitude and phase of the input to each coil element can be controlled independently to reduce the non-uniformity of the impressed RF $B_1^+$ field. The convex optimization technique has been used to obtain the optimum excitation parameters with iterative solutions for homogeneity in a selected ROI(Region of Interest). To demonstrate the technique, the multichannel transmission line coil was modeled together with a human head phantom at 400 MHz for the 9.4 T MRI system and $B_1^+$ fields are obtained. In this paper, all the optimized $B_1^+$ in each isolated ROIs are combined to achieve significantly improved homogeneity over the entire field of view. The simulation results for 9.4 T MRI systems are discussed in detail.

Effects or air current speeds on the growth or eggplant plug seedlings in a wind tunnel under artificial lighting (인공광하의 풍동내에서 기류속도가 가지 플러그묘의 생장에 미치는 영향)

  • 김용현
    • Journal of Bio-Environment Control
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    • v.7 no.1
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    • pp.9-14
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    • 1998
  • Air current speeds were controlled of 0.3, 0.5, 0.7 and 0.9 m.s$^{-1}$ to investigate the effects of air current speeds on the growth of eggplant plug seedlings (Solanum melongena L.) in a wind tunnel under artificial lighting. Growth of plug seedlings was influenced by the magnitude of air current speed and the traveling distance of regulated air flow. Stem length. ratio of length to diameter in stem, plant height .and number of leaves of plug seedlings decreased with the increasing air current speed and were significantly different at 5% level. Net photosynthetic rates of plug stand increased with the increasing air current speed and took a maximum value at the air current speed of 0.7~09 m.s$^{-1}$ . Stem diameter decreased and leaf area increased with the traveling distance of regulated air flow. Fresh weight and T/R ratio of dried weight were not influenced by the air current speed. Optimum control for microclimates inside the plug stand is needed to produce the uniform growth and high quality of plug seedlings in a semi-closed plant Production system under artificial lighting.

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The evaluation of applicability for agricultural reservoir of CAT(Catchment hydrologic cycle Assessment Tool) (CAT 모형의 농업용 저수지 유역에 대한 적용성 평가)

  • Jang, Cheol-Hee;Kim, Hyeon-Jun
    • Proceedings of the Korea Water Resources Association Conference
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    • 2011.05a
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    • pp.121-121
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    • 2011
  • 도시유역 물순환 해석 모형(Catchment hydrologic cycle Analysis Tool, CAT)은 기존의 개념적 매개변수 기반의 집중형 수문모형과 물리적 매개변수 기반의 분포형 수문모형의 장점을 최대한 집약하여, 도시유역 개발 전/후의 장/단기적 물순환 변화특성을 정량적으로 평가하고 물순환 개선시설의 효과적인 설계를 지원하기 위한 물순환 해석 모형이다. 이 모형은 수문학적으로 균일하게 판단되는 범위를 소유역으로 분할하여 지형학적 요인에 의한 유출 특성을 객관적으로 반영할 수 있으며, 개발 공간 단위별로 침투, 증발, 지하수 흐름 등의 모의가 가능하도록 하는 링크-노드 방식으로 개발되었다. 모형의 UI(User Interface)는 사용자가 손쉽게 모형을 적용/관리하고, 여러 시나리오를 동시에 효과적으로 모의하여 분석할 수 있도록 설계되었다. 또한, 모든 입/출력 자료를 엑셀이나 텍스트 형식과 연동되도록 하여 프로젝트별 매개변수 관리가 용이하도록 개발하였다. 특히 본 모형에서는 사용자의 목적에 맞는 다양한 물순환 개선시설(침투시설, 저류지, 습지, 빗물저장시설, 리사이클 및 외부급수 등)의 구현 및 모의가 가능하도록 개발하였다. CAT은 수자원의지속적확보기술개발사업(2008 ~ 2011)의 연구 성과로서 한국건설기술연구원에서 개발하였다. 2008년 말에 모형의 기본구조가 개발되었고, 2009년에는 세부 알고리즘인 증발산, 침투, 유역 유출, 지하수 유거, 하도추적 등의 모듈과 사용자 편의시스템이 개발되었다. 2010년에는 우리나라 논의 특성을 반영한 논 유출 해석 모듈 및 저류지, 침투시설, 습지, 빗물이용시설 및 하천에서의 취수와 도수 등과 같은 물순환 개선시설을 평가할 수 있는 모듈을 추가하여 개발하였으며 2010년 3월에 도시유역 물순환 해석 모형 1.0 베타 버전을 출시하였다. 2010년 12월 에는 1.0 베타 버전에 침투해석모듈(Green&Ampt, Horton), 논에서의 개량물꼬 배수, 침투녹지(Bioretention) 및 차집관거 기능을 추가하였고, 기타 GUI의 업그레이드 및 추가를 통하여 1.5 베타 버전을 출시하였다. 현재까지 여러 자연유역과 신도시 개발지역에 대한 적용을 통하여 모형의 적용성을 평가하였다. 본 연구에서는 기존의 자연유역과 신도시 개발지역 외에 농업용 저수지와 논 관개지구가 위치한 유역을 대상으로 모형의 적용성을 평가하고자 하였다. 대상유역은 농업용수 지구이며 농업수리시설의 종류와 규모가 다양할 뿐만 아니라 농촌유역으로써의 대표성을 가지고 기존의 관측자료가 풍부한 점 등을 고려하여 경기도 평택의 이동유역을 선정하였다. 이동유역은 행정구역으로는 경기도 용인시 이동면, 남사면 일원이며 서쪽은 경기도 오산시, 남쪽은 평택시, 안성시 그리고, 북쪽은 용인시와 인접하고 있다. 이동유역 내 주요시설로서 유역면적 $94.4km^2$의 이동저수지와 상류에 용덕저수지($12.41km^2$)와 미산저수지($4.39km^2$), 노곡저수지($2.00km^2$)의 3개 저수지가 위치하며 2개의 유입하천(진위천, 송전천)에 의해 이동저수지로 유입된다.

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Properties of $(Pb,La)TiO_3$ Ferroelectric Thin Films by Sol-Gel Method for the Infrared Sensors (졸-겔법에 의해 제작된 적외선 센서용 $(Pb,La)TiO_3$ 강유전체 박막의 특성)

  • Seo, Gwang-Jong;Jang, Ho-Jeong;Jang, Ji-Geun
    • Korean Journal of Materials Research
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    • v.9 no.5
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    • pp.484-490
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    • 1999
  • $(Pb,La)TiO_3$(PLT) thin films were prepared on Pt/SiO$_2$/Si substrates by the sol-gel method and investigated the crystalline and electrical properties according to La concentration and post-annealing temperatures. The PLT films annealed at above $600^{\circ}C$ were exhibited the typical perovskite structures regardless of La contents. When the $(Pb,La)TiO_3$(PT) films were doped with La concentration up to 10mol%(PLT-10), the degree of z-axis orientation was greatly decreased from 63% to 26%. From AES depth profiles for the PLT-10 samples, no remarkable inter-reaction between PLT film and lower Pt electrode was found. The remanent polarization$(2Pr,Pr_+-Pr_-)$ were increased from $4\muC\textrm{cm}^2 to 16\muC\textrm{cm}^2$ as the annealing temperature increased from $600^{\circ}C to 700^{\circ}C$. This result may be ascribed to the improvement of crystallinity by the high temperature post-annealing. The dielectric constant$({\varepsilon}r)$ and tangent loss(tan$\delta$) of the PLT-10 films annealed at $650^{\circ}C$ were about 193 and 0.02, respectively with the pyroelectric coefficient($\gamma$) of around $4.0nC/\textrm{cm}^2{\cdot}^{\circ}C at 30^{\circ}C$.

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A Bioassay Method with Radish Seedlings for Bioactive Substances (무우 유묘(幼苗)를 이용(利用)한 식물생리활성물질(植物生理活性物質)의 생물검정법(生物檢定法))

  • Hong, K.S.;Lim, H.K.;Cho, K.Y.
    • Korean Journal of Weed Science
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    • v.8 no.3
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    • pp.244-249
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    • 1988
  • Some experiments were conducted to utilize the raphanus test as a bioassay method for plant growth regulaters and hormonal herbicides. Among seven radish cultivars, the response of Jangbaegminong was the most sensitive and quantitative to ${\alpha}$-NAA and its coefficient of variation value was the lowest. The optimum application time of test compounds was estimated seven to nine days after seeding. After ${\alpha}$-NAA treatment the curvature angle of radish cotyledonary petiols was sharply increased to the maximum value at 24 hours after and was changed by light and temperature conditions. The curvature response was observed by application of ${\alpha}$-NAA, phenoxy and indole compounds but often plant growth regulators, $GA_3$ benzyladenine, ABA and homobrassinolide was not detected by this method. So this bioassay was useful to evaluate the activity of a compound as an auxin or a hormonal herbicide.

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The effect of Dynamite Explosion on Physical Properties of Orchard Soil (폭약(爆藥)에 의(依)한 과수원토양(果樹園土壤)의 물리성개량(物理性改良)에 관(關)한 연구)

  • Yoo, S.H.;Koh, K.C.;Cho, Y.K.
    • Korean Journal of Soil Science and Fertilizer
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    • v.11 no.2
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    • pp.61-66
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    • 1979
  • This experiment was conducted to find out the simple and economical method to improve physical properties of the soil that was very poor for the establishment of orchard. Jeonnam clay loam soils distributed mainly on rolling and hill side slope, were treated with the explosion of two kinds of dynamite at the depth of 1 m. The change of physical properties was investigated vertically and horizontally after soil profile had settled to some extent. The results were summarized as : 1. The original soil was very high in bulk density and soil hardness. Total porosity and aeration porosities were lower than critical level providing root elongation. It was more apparent in the subsoil than in the surface soil. 2. It was recognized that soil mass destruction and cracking by dynamite explosion decreased soil bulk density and soil hardness and increased porosity, especially non-capillary pores. 3. Effective radius of the improved physical properties by explosion with two dynamites was 100cm at 60cm depth and 30cm at 80cm depth. But with the use of three dynamites it was 100cm at 80cm depth. 4. It was thought that soil mass destruction and cracking caused by explosion was uneven in the two dynamites, and three dynamites was more effective to improve physical properties evenly. 5. With the use of two dynamites, Ammonium explosive was superior to gelatin dynamite.

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Traveling wave reactor atomic layer epitaxy process and characterization of ZnS and Tb-doped ZnS films (Traveling Wave Reactor Atomic Layer Epitaxy를 이용한 ZnS와 ZnS : Tb박막의 성장과 박막 특성의 연구)

  • 윤선진;남기수
    • Journal of the Korean Vacuum Society
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    • v.7 no.1
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    • pp.51-58
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    • 1998
  • ZnS and TB-doped ZnS (ZnS:Tb) thin films were grown by traveling wave reactor atomic layer epitaxy (AKE) and characterized using materials and surface analysis techniques. $ZnCl_2$, $H_2$S,and tris(2,26,6-tetramethyl-3,5-heptandionato) terbium ($Tb(TMHD)_3$) were used as the precursors in the growth of ZnS:Tb films. The dependence of Cl content in ZnS films on growth temperature was investigated using Rutherford backscattering spectrometry. The Cl content decreased from approximately 9 at.% to 1 at. % as increasing the growth temperature from 400 to $500^{\circ}C$. The segregation of Cl in near surface region was also observed by depth profiling using Auger electron spectroscopy. Scanning electron microscopic studies showed that the ALE-grown ZnS and ZnS:Tb film during ALE process using $Tb(TMHD)_3$was also investigated. Approximately 1 at.% of O in ZnS:Tb(0.5 at.%) film which showed a good crystallinity of hexagonal 2H structure.

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Self-forming Barrier Process Using Cu Alloy for Cu Interconnect

  • Mun, Dae-Yong;Han, Dong-Seok;Park, Jong-Wan
    • Proceedings of the Korean Vacuum Society Conference
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    • 2011.02a
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    • pp.189-190
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    • 2011
  • Cu가 기존 배선물질인 Al을 대체함에 따라 resistance-capacitance (RC) delay나 electromigration (EM) 등의 문제들이 어느 정도 해결되었다. 그러나 지속적인 배선 폭의 감소로 배선의 저항 증가, EM 현상 강화 그리고 stability 악화 등의 문제가 지속적으로 야기되고 있다. 이를 해결하기 위한 방법으로 Cu alloy seed layer를 이용한 barrier 자가형성 공정에 대한 연구를 진행하였다. 이 공정은 Cu 합금을 seed layer로 사용하여 도금을 한 후 열처리를 통해 SiO2와의 계면에서 barrier를 자가 형성시키는 공정이다. 이 공정은 매우 균일하고 얇은 barrier를 형성할 수 있고 별도의 barrier와 glue layer를 형성하지 않아 seed layer를 위한 공간을 추가로 확보할 수 있는 장점을 가지고 있다. 또한, via bottom에 barrier가 형성되지 않아 배선 전체 저항을 급격히 낮출 수 있다. 합금 물질로는 초기 Al이나 Mg에 대한 연구가 진행되었으나, 낮은 oxide formation energy로 인해 SiO2에 과도한 손상을 주는 문제점이 제기되었다. 최근 Mn을 합금 물질로 사용한 안정적인 barrier 형성 공정이 보고 되고 있다. 하지만, barrier 형성을 하기 위해 300도 이상의 열처리 온도가 필요하고 열처리 시간 또한 긴 단점이 있다. 본 실험에서는 co-sputtering system을 사용하여 Cu-V 합금을 형성하였고, barrier를 자가 형성을 위해 300도에서 500도까지 열처리 온도를 변화시키며 1시간 동안 열처리를 실시하였다. Cu-V 공정 조건 확립을 위해 AFM, XRD, 4-point probe system을 이용하여 표면 거칠기, 결정성과 비저항을 평가하였다. Cu-V 박막 내 V의 함량은 V target의 plasma power density를 변화시켜 조절 하였으며 XPS를 통해 분석하였다. 열처리 후 시편의 단면을 TEM으로 분석하여 Cu-V 박막과 SiO2 사이에 interlayer가 형성된 것을 확인 하였으며 EDS를 이용한 element mapping을 통해 Cu-V 내 V의 거동과 interlayer의 성분을 확인하였다. PVD Cu-V 박막은 기판 온도에 큰 영향을 받았고, 200 도 이상에서는 Cu의 높은 표면에너지에 의한 agglomeration 현상으로 거친 표면을 가지는 박막이 형성되었다. 7.61 at.%의 V함량을 가지는 Cu-V 박막을 300도에서 1시간 열처리 한 결과 4.5 nm의 V based oxide interlayer가 형성된 것을 확인하였다. 열처리에 의해 Cu-V 박막 내 V은 SiO2와의 계면과 박막 표면으로 확산하며 oxide를 형성했으며 Cu-V 박막 내 V 함량은 줄어들었다. 300, 400, 500도에서 열처리 한 결과 동일 조성과 열처리 온도에서 Cu-Mn에 의해 형성된 interlayer의 두께 보다 두껍게 성장 했다. 이는 V의 oxide formation nergyrk Mn 보다 작으므로 SiO2와의 계면에서 산화막 형성이 쉽기 때문으로 판단된다. 또한, V+5 이온 반경이 Mn+2 이온 반경보다 작아 oxide 내부에서 확산이 용이하며 oxide 박막 내에 여기되는 전기장이 더 큰 산화수를 가지는 V의 경우 더 크기 때문으로 판단된다.

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