• 한국응용약물학회:학술대회논문집
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• 한국응용약물학회 1995년도 춘계학술대회
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• pp.116-116
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• 1995

위염(gastritis), 위궤양(gastric ulcer)은 소화기 질환중에서 가장 빈도수가 높은 질병으로 위장관 점막이 위산에 의해 소화되어 버리므로서 궤양을 형성하는 상태를 말한다. 위염 및 위궤양의 발생빈도가 높은 것에 비해 발생원인은 정확히 밝혀져 있지 않으며 대체로 공격인자와 방어인자의 불균형 즉, 공격인자의 증가나 방어인자의 약화 또는 세균에 의한 감염에 의해 발생되는 것으로 알려져 있다. 일련의 식물엑스에 대하여 항위얌 및 항궤양효능에 관한 검색을 실시하여 노두의 M？H엑스가 현저한 효과가 있음을 예지하였으므로 그에 대하여 보다 구체적인 실험을 실시하였다. 즉 MeOH 엑스를 Hexane, CHCl$_3$, BuOH로 계통적으로 추출하여 상기의 분획 및 잔사인 물분획을 제조하여 이에 대한 실험을 실시하였다.

• Journal of Pharmaceutical Investigation
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• 제24권2호
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• pp.105-108
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• 1994

The ulcerogenic activity of a 3% ketoprofen gel (ID-GEL) after its transdermal application in rats was determined with the Litchfield and Wilcoxon method in reference to the oral administration of ketoprofen in a suspension. The $UD_{50}$ (dose producing ulcers in 50%, of the rats tested) of ID-GEL after its transdermal application was approximately 4 times greater than that after the oral administration of the drug, indicating that the ulcerogenic activity of ketoprofen was much lowered with its transdermal application.

• 한국산학기술학회:학술대회논문집
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• 한국산학기술학회 2009년도 춘계학술발표논문집
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• pp.607-611
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• 2009

Stomach ulcer is the sickness with high frequency of occurrence at the digestive organs and is usually induced by a disproportion of an aggressive factor and a defense factor. To find the medicines having comparative effect to $Stillen^{(R)}$ currently on sale, we screened SHI-7004 and carried out following experiments; Effects of HCl-EtOH induced gastric lesions measuring test, Acid-Neutralizing Capacity, DPPH antioxidation activity, effect of stomach glands secrection. We can suggest that this herbal medicines could be a promising drug for the treatment of gastrc ulcers.

• 대한세포병리학회지
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• 제2권2호
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• pp.105-110
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• 1991

We report a case of hepatoma with duodenal metastasis in a 53 year-old male patient. Hepatoma was confirmed by fine needle aspiration cytology technique, and duodenal metastasis by gastrofiberscopic biopsy. Duodenal metastasis of hepatoma is rare. We briefly review the role of fine needle aspiration cytology technique in diagnosis of hepatoma.

• 대한한의학방제학회지
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• 제19권1호
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• pp.253-261
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• 2011

Objectives : The prevalence of peptic ulcer disease is estimated about 10% in Korea, and has declined due to Helicobacter pylori eradication therapy. Symptoms of peptic ulcer are postprandial epigastric pain, hunger pain, anorexia, nauea, vomiting, soreness, postprandial fullness, postparandial discomfort. The purpose of the study was to evaluate the effectiveness of the Anjungsan in the improvement of the symptoms in patients with peptic ulcer. Methods : After taking Anjungsan to patient with peptic ulcer, Examined to assess the improvemnet by Ordinal Scale VI grade and VAS. Results : Patients with symptoms of the appeal was taking Anjungsan gets better after 3 dyas appeared to be more than half. And 11 days after treatment all symptoms were improved under the VAS 1-2 except for epigastric lump sensation. Conclusions : After treatment with Anjungsan, patient showed improvement in all symptoms associated with peptic ulcer.

• 한방안이비인후피부과학회지
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• 제33권2호
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• pp.164-173
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• 2020

Objectives : The purpose of this study is to report the effectiveness of using korean medical treatment on ulcer occurred in Anus and Vulva. Methods : We treated the patient with Taglisodog-eum(托裏消毒飮), acupuncture, and korean medical treatment using herb such as ointment and fumigation therapy. VAS score, Photographs were used to evaluate the effects of treatment. Results : After the total treatments, VAS score decreased from 7 to 1. In this case, we treated ulcer and checked regeneration of new tissue. Conclusions : The result suggests that Korean medical treatment including Taglisodog-eum(托裏消毒飮) can be effective in treatingulcer.

• Journal of Oral Medicine and Pain
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• 제19권1호
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• pp.117-124
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• 1994

Parotid and whole saliva were collected from 27 healthy adults, from 25 years of age to 30, and from 27 patients with oral ulcer, from 23 years of age to 61. The amount of each Salivary immunoglobulin A was measured by single radial immunodiffusion (SRID) technique. Results were as follows : 1. There was no significant difference between the normal group and the disease group in the concentration of immunoglobulin A in whole saliva. 2. The concentration of immunoglobulin A in parotid saliva of the normal group was higher than the disease group and the difference was statistically significant between the two groups. (p<0.01) 3. The concentration of immunoglobulin A of the parotid saliva in both groups was higher than that of the whole saliva.

• 식품기술
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• 제15권3호
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• pp.84-91
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• 2002

식이 섬유질에는 여러 종류가 있고 그 종류에 따라 short chain fatty acid(SCFA)의 생산 등 생리작용도 크게 다르다. 식이 섬유질 중 수용성은 장내세균의 발효를 받아 butyrate, acetate, propionate 등의 SCFA를 생산한다. 수용성 식이 섬유질을 섭취함으로서 SCFA의 생산을 증가시키고 대장점막증식, 물.전해질 흡수 촉진, 혈류량을 증가시키는 작용 외에 면역조절 작용을 가지고 있다. 식이 섬유는 장관계 질환 중의 하나인 염증성 장질환 특히 궤양성 대장염의 치료법으로서 기대되고 있으며, 암세포 연구에서는 butyrate 가 apoptosis 유도작용과 발암유전자의 억제효과가 확인되고 있으나 역학 연구에서는 식이 섬유질에 의한 대장암 예방효과는 아직 불확실하다. 모든 유형의 식이 섬유질은 건강 식품으로서 사용되고 있으며, prebiotic으로서도 주목받고 있다. 또한 경장 영양제에도 각종의 식이 섬유질이 첨가되어 있다. 그러나 충분한 양의 비타민과 무기질을 함유한 고섬유질식과, 건강 식품으로서의 식이 섬유질을 같은 의미로 해석하기에는 여러 가지 문제가 남아 있다.

• 약학회지
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• 제37권6호
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• pp.581-590
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• 1993

In a preliminary screening of the plant extracts for the antigastritic action in rats, the extract of Aralia elata(Araliaceae) showed positive activity in HCI plus ethanol induced gastric lesion. Systematic fractions with hexane, chloroform, ethyl acetate and butanol resulted in the most patent activity with the butanol fraction: This butanol fraction at the oral dose of 200 mg/kg exhibited significant inhibition of absolute alcohol induced gastric lesion which was more potent than 100 mg/kg of cimetidine and had significant stimulation of mucus secretion. The butanol fraction showed significant decreases in the ulcer indices of Shay ulcers and inhibition of gastric juice secretion with acid output in pylorus-ligated stomachs of rats. It also suppressed the acetic acid induced gastric ulcer. These results might suggest that the butanol fraction had inhibitory action in gastric lesion and ulceration through inhibition of gastric acid secretion and stimulation of mucin secretion in the stomachs of rats.

• 대한족부족관절학회지
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• 제18권3호
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• pp.133-136
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• 2014

Skin grafting is often required for diabetic ulcerative foot lesions. In skin grafting, effective regional or local anesthesia into the donor and recipient areas plays a significant role in continuous control of pain. We report on a technique of ultrasound-guided nerve block on the femoral, sciatic, and lateral femoral cutaneous nerves in large split-thickness skin grafting for ulcer of the foot and leg.