• Title/Summary/Keyword: 국한성

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Carcinoma of the Colon and Rectum : Sonographic Findings and usefulness (Cases Review) (결직장암의 초음파검사 소견 및 유용성(증례 중심으로))

  • Jung, Hong-Ryang;Kim, Myeong-Soo;Sim, Hyun-Sun
    • Journal of radiological science and technology
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    • v.26 no.2
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    • pp.43-47
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    • 2003
  • Colorectal cancer produce focal mass or segmental thickening which can be detected with sonography. The purpose of this study was to describe sonographic findings of colorectal cancer. we reviewed sonograms of 51 patients with colorectal cancer in whom sonography was performed before colon study. In 51 patients who had more common coloretal cancer 27cases(53%) had 40 to 50 years of age(60%). Sonographic findings included segmental thickening 42cases, or irregular mass 9 cases. With careful examination, these findings can be detectable, and therefore bowel should be carefully examination in patients with sign and symptoms suggesting carcinoma of the colon and rectum.

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Twice Daily Radiation Therapy Plus Concurrent Chemotherapy for Limited-Stage Small Cell Lung Cancer (국한성병기 소세포폐암에서 하루 두 번 분할조사와 동시 화학방사선치료)

  • Yeo Seung-Gu;Cho Moon-June;Kim Sun-Young;Kim Ki-Whan;Kim Jun-Sang
    • Radiation Oncology Journal
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    • v.24 no.2
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    • pp.96-102
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    • 2006
  • Purpose: A retrospective study was performed to evaluate the efficiency and feasibility of twice daily radiation therapy plus concurrent chemotherapy for limited-stage small cell lung cancer in terms of treatment response, survival, patterns of failure, and acute toxicities. Materials and Methods: Between February 1993 and October 2002, 76 patients of histologically proven limited-stage small cell lung cancer (LS-SCLC) were treated with twice daily radiation therapy and concurrent chemotherapy. Male was in 84% (64/76), and median age was 57 years (range, 32-75 years). Thoracic radiation therapy consisted of 120 or 150 cGy per fraction, twice a day at least 6 hours apart, 5 days a week. Median total dose was 50.4 Gy (range, 45-51 Gy). Concurrent chemotherapy consisted of CAV ($cytoxan\;1000mg/m^2,\;adriamycin\;40mg/m^2,\;vincristine\;1mg/m^2$) alternating with PE ($cisplatin\;60mg/m^2,\;etoposide\;100mg/m^2$) or PE alone, every 3 weeks. The median cycle of chemotherapy was six (range, 1-9 cycle). Prophylactic cranial irradiation (PCI) was recommended to the patients who achieved a complete response (CR). PCI scheme was 25 Gy/10 fractions. Median follow up was 18 months (range, 1-136 months). Results: Overall response rate was 86%; complete response in 39 (52%) and partial response in 26 (34%) patients. The median overall survival was 23 months. One, two, and three year overall survival rate was 72%, 50% and 30%, respectively. In univariate analysis, the treatment response was revealed as a significant favorable prognostic factor for survival (p<0.001). Grade 3 or worse acute toxicities were leukopenia in 46 (61%), anemia in 5 (6%), thrombocytopenia in 10 (13%), esophagitis in 5 (6%), and pulmonary toxicity in 2 (2%) patients. Of 73 evaluable patients, 40 (55%) patients subsequently had disease progression. The most frequent first site of distant metastasis was brain. Conclusion: Twice daily radiation therapy plus concurrent chemotherapy produced favorable response and survival for LS-SCLC patients with tolerable toxicities. To improve the treatment response, which proved as a significant prognostic factor for survival, there should be further investigations about fractionation scheme, chemotherapy regimens and compatible chemoradiotherapy schedule.

The Results and Prognostic Factors of Chemo-radiation Therapy in the Management of Small Cell Lung Cancer (항암화학요법과 방사선 치료를 시행한 소세포폐암 환자의 치료 성적 -생존율과 예후인자, 실패양상-)

  • Kim Eun-Seog;Choi Doo-Ho;Won Jong-Ho;Uh Soo-Taek;Hong Dae-Sik;Park Choon-Sik;Park Hee-Sook;Youm Wook
    • Radiation Oncology Journal
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    • v.16 no.4
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    • pp.433-440
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    • 1998
  • Purpose : Although small ceil lung cancer (SCLC) has high response rate to chemotherapy and radiotherapy (RT), the prognosis is dismal. The authors evaluated survival and failure patterns according to the prognostic factors in SCLC patients who had thoracic radiation therapy with chemotherapy. Materials and Methods : One hundred and twenty nine patients with SCLC had received thoracic radiation therapy from August 1985 to December 1990. Seventy-seven accessible patients were evaluated retrospectively among 87 patients who completed RT. Median follow-up period was 14 months (2-87months). Results : The two years survival rate was 13$\%$ with a median survival time of 14 months. The two year survival rates of limited disease and extensive disease were 20$\%$ and 8$\%$, respectively, with median survival time of 14 months and 9 months, respectively. Twenty two patients (88$\%$) of limited disease showed complete response (CR) and 3 patients (12$\%$) did partial response (PR). The two year survival rates on CR and PR groups were 24$\%$ and 0$\%$, with median survival times of 14 months and 5 months. respectively (p=0.005). No patients with serum sodium were lower than 135 mmol/L survived 2years and their median survival time was 7 months (p=0.002). Patients whose alkaline phophatase lower than 130 IU/L showed 26$\%$ of 2 year survival rate and showed median survival time of 14 months and those with alkaline phosphatase higher than 130 IU/L showed no 2 year survival and median survival time of 5 the months, respectively (p=0.019). No statistical differences were found according to the age, sex, and performance status. Among the patients with extensive disease, two rear survivals according to the metastatic sites were 14$\%$, 0$\%$, and 7$\%$ in brain, liver, and other metastatic sites, respectively, with median survival time of 9 months, 9 months, and 8 months, respectively (p>0.05). Two year survivals on CR group and PR group were 15$\%$ and 4$\%$, respectively, with a median survival time of 11 months and 7 months, respectively (p=0.01). Conclusion : For SCLC, complete response after chemoradiotherapy was the most significant prognostic tactor. To achieve this goal. there should be further investigation about hyperfractionation, dose escalation, and compatible chemo-radiation schedule such as concurrent chemo-radiation and early radiation therapy with chemotherapy.

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lustering of Categorical Data using Rough Entropy (러프 엔트로피를 이용한 범주형 데이터의 클러스터링)

  • Park, Inkyoo
    • The Journal of the Institute of Internet, Broadcasting and Communication
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    • v.13 no.5
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    • pp.183-188
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    • 2013
  • A variety of cluster analysis techniques prerequisite to cluster objects having similar characteristics in data mining. But the clustering of those algorithms have lots of difficulties in dealing with categorical data within the databases. The imprecise handling of uncertainty within categorical data in the clustering process stems from the only algebraic logic of rough set, resulting in the degradation of stability and effectiveness. This paper proposes a information-theoretic rough entropy(RE) by taking into account the dependency of attributes and proposes a technique called min-mean-mean roughness(MMMR) for selecting clustering attribute. We analyze and compare the performance of the proposed technique with K-means, fuzzy techniques and other standard deviation roughness methods based on ZOO dataset. The results verify the better performance of the proposed approach.

The Clinical and Histopathological Study of Laryngeal mass (후두 종양의 임상적 및 병리조직학적 고찰)

  • 김화성;한경수;이준기;정덕희;박재훈
    • Proceedings of the KOR-BRONCHOESO Conference
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    • 1981.05a
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    • pp.9.1-10
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    • 1981
  • The clinical study of 183 cases of laryngeal mass was observed and 88 cases of vocal nodule and polyp which is confirmed histopathologically, were clinically classified into 30 cases of vocal nodule, 48 cases of localized vocal polyp, 10 cases of diffuse vocal polyp, and the following results of microscopic examination were obtained. I. The clinical study of laryngeal mass 1. Among total cases of 183, vocal nodule is 82(45%) vocal polyp 53(29%) postintubation granuloma 3(1%) laryngeal papilloma 18(10%) tuberculosis 2(1%) cancer 25(14%). 2. The sex ratio of male to female is 3:4 in vocal nodule, 1:1 in vocal polyp, 1:2 in postintubation granuloma, 3:2 in laryngeal papilloma, 11:1 in cancer. 3. The age distribution is third-fourth decade in vocal nodule, fourth-fifth decade in vocal polyp, third decade in postintubation granuloma, second and fifth decade in laryngeal tuberculosis, sixth decade in laryngeal cancer. 4. The distribution of symptoms is 5 month. -1 year in vocal nodule and polyp, less than 1 year in laryngeal papilloma and postintubation granuloma, 1 year-3 year in laryngeal tuberculosis and cancer. 5. The location of the lesion is between the anterior 1/3 and middle 1/3 in vocal nodule and polyp and papilloma, middle 1/3 and posterior 1/3 in postintubation granuloma, and is diffusely spread on the entire vocal cord in laryngeal tuberculosis and cancer. 6. The side of the lesion is bilateral in vocal nodule and papilloma and the ratio of right to left is 5:3 in vocal polyp, 2:1 in postintubation granuloma. 7. The size is 1~2mm(67%) in vocal nodule, 3~5mm(42%) in vocal polyp, 6~10mm (67%) in postintubation granuloma, 1~2mm (39%) in papilloma, more than 10mm in tuberculosis and cancer. 8. Among the symptoms, the hoarseness is in more than 90% of disease entity, the sore-throat in tuberculosis and cancer, the dyspnea in postintubation granuloma and papilloma and tuberculosis and cancer. 9. In the past history, certain relationship with smoking is noted in cancer (40%) and tuberculosis(50%) and the history of frequent attack of URI is in papilloma(33%). 10. In occupation, certain statistical significance was not noted. II. The histopathological study of vocal nodule and polyp. 1. Most polyps and nodules were covered with stratified squamous epithelium, but focal hyperkeratosis, parakeratosis, acanthosis and atrophy were rather frequently observed. Hyperkeratosis and acanthosis was most frequently seen.

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The precise analysis on the watershed based river-groundwater interaction (유역단위 하천 지하수 상호작용의 하천-정밀분석)

  • Kim, Nam-Won;Yoo, Sang-Yeon;Chung, Il-Moon;Lee, Jeong-Woo
    • Proceedings of the Korea Water Resources Association Conference
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    • 2008.05a
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    • pp.1919-1923
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    • 2008
  • 지하수와 지표수의 상호작용은 혼합대(hyporheic zone)와 홍수터 물수지에도 영향을 끼치며 특히 생물학적인 측면에서 중요한 역할을 하는 혼합대의 경우 유역 전반에 걸쳐 불균일한 분포를 나타낸다. 그런데 기존하천-대수층 상호작용에 대한 연구는 하천변에 근접한 지역의 대한 연구로 국한되어 있다. 따라서 단순히 하천-대수층간 상호작용의 영향을 하천변에 국한시키는 것이 아니라 유역규모로 확장하여 유역단위 지표수-지하수 상호작용에 대한 심도 있는 해석을 해야만 보다 정확한 지표수-지하수의 연계운영이 가능하다. 본 연구에서는 유역단위 지표수-지하수 상호작용을 해석하기 위해 완전연동형 SWAT-MODFLOW를 이용하여 하천과 대수층의 상호작용의 강도를 하천 구간별로 찾아내고 그 교환의 공간적 범위도 추정함으로써 혼합대연구를 위한 실증을 수행하고자 한다. 유역 단위의 지표수-지하수 상호작용을 해석하기 위하여 SWAT-MODFLOW모형을 안양천 중상류 유역에 적용시킨 결과 하천과 대수층간에 상호작용의 영향범위와 영향강도 등을 파악할 수 있었다. 하천-대수층 상호작용의 정밀분석을 통한 영향권 산정 및 혼합대의 발생범위 예측은 향후 하천복원 사업시 수생생태계 건강성 지표와 관련된 연구에 유용하게 활용될 수 있을 것이다.

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A Case Report of Lymphangioma Circumscriptum on Scalp (두피에 발생한 국한성 림프관종의 치험례)

  • Lee, Dong-Gwan;Shin, Hea-Kyeong;Seoul, Jung-Hyun;Choi, Jun
    • Archives of Craniofacial Surgery
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    • v.9 no.1
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    • pp.38-40
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    • 2008
  • Purpose: Lymphangioma circumscriptum is a rare, congenital benign hamartous malformation, caused by the saccular dilatation of lymph channels lines by normal, single cell, lymphatic endothelia that present as local eruptions of persistent, grouped, translucent vesicles. The lymphangioma circumscriptum lesions may occur on axillary fold shoulder, neck proximal limbs and buccal mucosa. We reported a rare case of lymphangioma circumscriptum on the scalp. Methods: A 15-year-old girl with a $5{\times}3cm$ sized lymphangioma circumscriptum on scalp was examined. It was defined a boundry by ultrasound. And then, a tissue crescent type expander with 120 cc normal saline was inserted on occipital area for a month. After confirmed safety margin of the excised lymphangioma circumscriptum on frozen biopsy and the scalp flap was elevated and covered with empty space. Results: A histopathologic finding revealed that lymphangioma circumscriptum. During 11 months follow up, no relapse was found. Conclusion: We described a rare case of lymphangioma circumscriptum on scalp. By using a tissue expander and excision, we achieved no recurrence and aesthetically satisfactory outcome.

Surgical Treatment of T4 Lung Cancer with the Use of Extracorporeal Circulation -A case report of long-term survival - (체외순환을 이용한 T4 폐암의 수술적 치험 -장기 생존 1예 보고-)

  • 조규도;조민섭;윤정섭;김치경;곽문섭
    • Journal of Chest Surgery
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    • v.37 no.2
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    • pp.180-183
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    • 2004
  • We report a case of a patient with lung cancer, which invaded the left atrium and pericardium. Right middle and lower lobectomy was performed with the use of the extracorporeal circulation. Postoperative pathologic examination revealed the stage of IIIB (T4N1MO). Although the postoperative clinical course was complicated by acute localized right sided pulmonary edema and the bronchopleural fistula, the patient recovered smoothly after the procedure of omentopexy with pedicled graft of greater omentum in closing the BPF. As of August 2003, he has been followed up for 6 years and he is healthy without any evidence of recurrence. We could not find any report concerning lung cancer resection using cardiopulmonary bypass in Korean literature and believe this is the first report, especially with long-term survival.

An Accuracy Enhancement for Anchor Free Location in Wiresless Sensor Network (무선 센서 네트워크의 고정 위치에 대한 정확도 향상)

  • Kim, Yong-Gil;Moon, Kyung-Il
    • The Journal of the Institute of Internet, Broadcasting and Communication
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    • v.18 no.5
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    • pp.77-87
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    • 2018
  • Many researches have been focused on localization in WSNs. However, the solutions for localization in static WSN are hard to apply to the mobile WSN. The solutions for mobile WSN localization have the assumption that there are a significant number of anchor nodes in the networks. In the resource limited situation, these solutions are difficult in applying to the static and mobile mixed WSN. Without using the anchor nodes, a localization service cannot be provided in efficient, accurate and reliable way for mixed wireless sensor networks which have a combination of static nodes and mobile nodes. Also, accuracy is an important consideration for localization in the mixed wireless sensor networks. In this paper, we presented a method to satisfy the requests for the accuracy of the localization without anchor nodes in the wireless sensor networks. Hop coordinates measurements are used as an accurate method for anchor free localization. Compared to the other methods with the same data in the same category, this technique has better accuracy than other methods. Also, we applied a minimum spanning tree algorithm to satisfy the requests for the efficiency such as low communication and computational cost of the localization without anchor nodes in WSNs. The Java simulation results show the correction of the suggested approach in a qualitative way and help to understand the performance in different placements.

한국형 표준원전 화재사건에 대한 2단계 PSA 불확실성 분석

  • 김시달;안광일;박수용;김동하;진영호
    • Proceedings of the Korean Nuclear Society Conference
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    • 1998.05a
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    • pp.881-886
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    • 1998
  • 한국형 표준 원진(울진 원전 3,4호기)화해 사건에 대한 2 단계 확률론적 안전성평가 (Level 2PSA) 에서 격납건물 파손모드에 큰 영향을 준다고 판단되는 현상들에 대한 불확실성 분석을 수행하였다. 불확실성 분석 대상은 주로 민감도분석 및 기존 2단계 PSA수행결과 중요한 인자로 선정된 8가지 주요 현상들로 국한하였다. 수행 방법은 성층화 추출방식 (Latin Hypercube Sampling)으로부터 발생된 1000개의 표본을 사용하였고, 분석결과는 두가지 불확실성 측도로 제시하였으며, 사용된 코드는 2 단계 PSA 분석용 전산코드인 CONPAS 이다. 불확실성 관리측면에서. 제일 불확실성이 높은 격납건물 파손모드인 원자로 공동바닥관통의 불확실성 인자를 줄이기 위해서는 CR-EJECT 현상에 대한 불확실성 을 줄여야 할 것이다.

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