• Title/Summary/Keyword: 국방과학연구소

Search Result 857, Processing Time 0.021 seconds

Development of a Platform for Natural Killer Cell Therapy with Antiviral Efficacy (항바이러스 효능을 가진 자연살해세포 치료제 플랫폼 개발)

  • Dongsoo Kim;Hyeongseok Yun;Jinhui Lee;Dayoung Yeon;Chi Ho Yu;Se Hum Gu;Young-Jo Song;Jung-Eun Kim;Seung-Ho Lee;Yong Han Lee;Gyeung Haeng Hur;Junghwa Kang
    • Journal of the Korea Institute of Military Science and Technology
    • /
    • v.27 no.1
    • /
    • pp.107-115
    • /
    • 2024
  • Various vaccines were rapidly developed during the COVID-19 pandemic to prevent and treat infections but global infections continue, and concerns about new mutations and infectious diseases persist. Thus, active research focuses on developing, producing, and supplying vaccines and treatments for various infectious diseases and potential pandemics. Natural killer(NK) cells, as innate immune cells, can recognize and eliminate abnormal cells like virus-infected and cancer cells. Hence, their development as anticancer and antiviral treatments is rapidly advancing. In this study, optimal short-term culture conditions were identified for allogeneic NK cells by simplifying the culture process through the isolation of NK cells(referred to as NKi cells) and eliminating CD3+ cells(referred to as CD3- cells). NK cells demonstrated reduced viral titer in injection of NK cells into SARS-CoV-2 infected ACE-tg mice increased survival. The study's findings could form the basis for an antiviral treatment platform that swiftly responds to new viral disease pandemics.

Avionics Architecture Design for Military Unmanned Aerial Vehicles (군용 무인기의 항공전자 아키텍처 설계)

  • Jae Ick, Shim;Jae Won, Choi;Yong Tae, Kim;Dong Wan, Yoo;Kook Bo, Yang;Hyun Seok, Ha;Sang Jin, Kim;Seung Yul, Lee;Sang Jun, Jung
    • Journal of the Korea Institute of Military Science and Technology
    • /
    • v.25 no.6
    • /
    • pp.628-636
    • /
    • 2022
  • This paper describes the design of the avionics architecture for military unmanned aerial vehicles considering the airworthiness requirements for the first time. This design considers the redundancy in the system data bus and the power system and the data link system to meet the system safety requirements of the airworthiness requirements of military UAVs. This avionics architecture design has been verified through the system integration test and the flight test after manufacturing the UAV.

Progressive Test and Evaluation Strategy for Verification of KF-X AESA Radar Development (한국형 전투기(KF-X) AESA 레이다 개발 검증을 위한 점진적인 시험평가 전략)

  • Shinyoung Cho;Yongkil Kwak;Hyunseok Oh;Hyesun Ju;Hongwoo Park
    • Journal of the Korea Institute of Military Science and Technology
    • /
    • v.27 no.3
    • /
    • pp.387-394
    • /
    • 2024
  • This paper describes a progressive test and evaluation strategy for verification of Korean Fighter eXperimental (KF-X) AESA(Active Electronically Scanned Array) radar development. Three progressive stages of development test and evaluation were officially performed from simulated test conditions to actual operating conditions according to standards: radar function/performance and avionics integration. KF-X AESA radar development is repeatedly verified by progressive stages consisting of five tests: Roof-lab ground test, System Integration Laboratory(SIL) ground test, Flying Test Bed(FTB) test, KF-X ground test, and KF-X flight test. As a result, the risk factor decreases as stages and tests progress. Therefore, development test and evaluation of KF-X AESA radar are successfully performed at low development risk.

Ferromagnetic Target Detection in the Ocean Using Drone-based Magnetic Anomaly Detection (드론 기반 자기 이상 탐지를 이용한 해양에서의 강자성 표적 탐지)

  • Sinhyuk Yim;Dongkyu Kim;Jihun Yoon;Eunseok Bang;Seokmin Oh;Bona Kim;Kyumin Shim;Sangkyung Lee
    • Journal of the Korea Institute of Military Science and Technology
    • /
    • v.27 no.3
    • /
    • pp.338-345
    • /
    • 2024
  • Magnetic anomaly signals from the ferromagnetic targets such as ships in the sea are measured by drone-based magnetic anomaly detection. A quantum magnetometer is suspended from the drone by 4 strings. Flight altitude and speed of drone are 100 m and 5 m/s, respectively. We obtain magnetic anomaly signals of few nT from the ships clearly. We analyze the signal characteristics by the ferromagnetic target through simulation using COMSOL multiphysics.

Adaptive Mission Control Architecture with Flexible Levels of Autonomy (유연한 자율화 수준의 적응형 임무통제 아키텍처)

  • Wonik Park;Hojoo Lee;Joonsung Choi;Tokson Choe;Chonghui Kim
    • Journal of the Korea Institute of Military Science and Technology
    • /
    • v.27 no.2
    • /
    • pp.265-276
    • /
    • 2024
  • The future battlefield operation concept does not focus on advanced and complete weapon systems, but requires a new battlefield operation concept that can effectively demonstrate offensive power by combining a large number of low-cost, miniaturized weapons. Recently, research on the autonomous application of major technologies that make up the mission control system is actively underway. However, since the mission control system is still dependent on the operator's operating ability when operating multiple robots, there are limitations to simply applying the automation technology of the existing mission control system. Therefore, we understand how changes in operator capabilities affect multi-robot operation and propose an adaptive mission control architecture design method that supports multi-robot integrated operation by adjusting the level of autonomy of the mission control system according to changes in operator capability.