• Journal of dental hygiene science
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• 제13권1호
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• pp.62-70
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• 2013

The aim of this study was to analyze factors related to xerostomia in adults aged 30 years and over. The data were analyzed using the t-test, one-way ANOVA and multiple linear regression analysis in the SPSS version 12.0 program. The results were as follow. 1. The respondents who were older than 51 years old, unemployed and had less than 3 million won of average monthly income were more aware of xerostomia (p<0.05). 2. The respondents who answered poor and moderate for their general and oral health and the group with duplicate medication and comorbidity were more aware of xerostomia (p<0.05). 3. The respondents that had problems in chewing, communication, ordinary activities and complained of pain discomfort and suffered from anxiety depression were more aware of xerostomia (p<0.001). 4. The respondents that answered frequent dryness on their skin, eyes, lips, and nasal mucosa were more aware of xerostomia (p<0.001). 5. Xerostomia showed highest correlation with quality of life ($\beta$=0.436) followed by the number of medications ($\beta$=0.239), sense of entire body dryness ($\beta$=0.200), feeling of hopelessness ($\beta$=0.160) and number of oral mucosa disease symptoms ($\beta$=0.099) (p<0.05). According to the results of the study, xerostomia may cause deterioration in quality of life. Thus, it is advised to improve the patient management system among dental professions to prevent various complications caused by xerostomia and conduct regular health education on the cause and management method of xerostomia.

• Journal of Oral Medicine and Pain
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• 제26권3호
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• pp.215-224
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• 2001

서울대학교 치과병원 구강진단과에 구강건조증을 주소로 내원한 환자중 비자극 전타액 분비율이 0.2ml/min이하인 환자 40명과 구강건조증의 증상 및 징후가 없고 정상 타액분비율을 보이는 10명을 대상으로 비자극 전타액 분비율을 측정하고 타액선 스캔 검사를 실시하여 주타액선의 스캔 영상을 정량화한 후 이의 상관관계를 조사한 결과 다음과 같은 결론을 얻었다. 1. 구강건조증 환자군 및 정상 대조군에서 타액선 스캔 영상의 정량적 분석시 이하선 및 악하선 모두에서 좌우측 사이의 유의성 있는 차이가 없었다. 2. 타액선 스캔 영상의 정량적 분석시 구강건조증 환자군은 대조군에 비하여 악하선, 이하선 및 악하선의 합, 양측 악하선 합에서 유의한 차이를 보였다. 3. 대조군에서 타액선 스캔 영상의 정량적 수치와 비자극 전타액 분비율과는 유의성 있는 상관관계가 관찰되지 않았으나, 구강건조증 환자군에서는 유의성 있는 상관관계가 관찰되었다. 4. 구강건조증 환자군을 비자극성 전타액 분비율에 따라 세분하였을 때, 비자극 전타액 분비의 감소가 극심하여 그 측정이 불가능하였던 군은 대조군 및 나머지 구강건조증 환자군에 비하여 타액선 스캔 영상의 정량적 수치에서 유의한 차이를 보였다.

• Journal of Oral Medicine and Pain
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• 제36권1호
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• pp.21-24
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• 2011

Xerostomia is subjective feeling of dry mouth, a symptom that may or may not be accompanied by hyposalivation, an objective decrease in salivary flow. There are many causes induced xerostomia like drugs, salivary gland diseases, radiation therapy to the head and neck region, Sjogren syndrome, emotional stress etc. Insufficient salivary flow creates complications with oral candidiasis, dental caries, periodontitis, halitosis, dysgeusia. So finally, these complications lead to an overall decline in quality of life. Managements of xerostomia are eliminating or alterating the etiologic factors, relieving symptoms, preventing or correcting the consequences of salivary dysfunction, treating underlying disease and stimulating salivation. One of the salivation stimulation agents studied to treat xerostomia was the pilocarpine muscarinic agonist. Pilocarpine is one of salivation stimulants, a parasympathomimetic drug and non-selective muscarinic receptor agonist. Systemic pilocarpine has been used to stimulate salivary secretion. But systemic administration of pilocarpine has limitations such as increased risk of side effects and contraindications. Side effects of systemic pilocarpine administration are sweating, urinary and gastrointestinal disturbance, risk of cardiovascular and pulmonary disorders. This drug must be used carefully by patients with controlled asthma, chronic bronchitis, pulmonary or cardiac disease. Patient with acute asthma, narrow angle glaucoma, iritis should not use pilocarpine. Like this, systemic pilocarpine has many limitations. So, many investigators also have looked at the effectiveness of topical pilocarpine. Here we present patients with xerostomia which was relieved by pilocarpine mouthwash.

• Journal of Oral Medicine and Pain
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• 제30권4호
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• pp.383-389
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• 2005

Xerostomia is defined as a subjective complaint of dry mouth that may be perceived when there is insufficient mucosal wetting. However, the diagnosis and treatment of xerostomia is not that simple because of the fact that the subjective awareness of dry mouth is not always correlated with a diminution in the flow of saliva and there is always a difference between individuals in salivary flow rates needed for normal oral function. In the present study, the aim was to develop a questionnaire to evaluate the dry mouth symptoms and to analyze its reliability and usability as a diagnostic and analytic tool for xerostomia. The questionnaire which consists of 6 Visual Analogue Scale(VAS) type questions to evaluate the subjective oral dryness and 4 questions to evaluate behavior to avoid oral dryness was developed and administered twice with 1 week's interval to the healthy 88 young adults without dry mouth symptoms(44 males and 44 females; mean age was $25.6{\pm}3.1$ years in male and $24.3{\pm}2.1$ years in female). The results were as follows. 1 The intraclass correlation coefficients of 6 questions to evaluate the subjective oral dryness were as significantly high as 0.767 for the degree of oral dryness at other times of the day, 0.850 for the amount of saliva in the mouth, and 0.791 for the degree of effect on daily life due to oral dryness and as high as 0.563 for the degree of oral dryness at night or on awakening, 0.674 for the degree of oral dryness during eating, and 0.641 for the degree of difficulty in swallowing foods. 2. Cronbach's alpha value of 6 questions was 0.982. It can be concluded that the series of questions to evaluate the subjective oral dryness has high internal consistency. 3. Cohen's kappa values of 4 questions to evaluate behavior to relieve oral dryness were as significantly high as 0.850 for the frequency of keeping a glass of water at the bedside and as high as 0.506 the frequency of awakening during sleeping due to oral dryness, 0.419 for the frequency of sipping liquids to aid in eating dry foods, and 0.407 for the frequency of using a candy or chewing gum due to oral dryness. From the results, it can be concluded that the questionnaire consisting of 6 VAS type questions to evaluate the subjective oral dryness and 4 questions to evaluate behavior to relieve oral dryness has reliability of good to excellent level, and that the series of 6 VAS type questions has significantly high internal consistency to evaluate the subjective oral dryness.

• Journal of Oral Medicine and Pain
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• 제33권1호
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• pp.67-73
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• 2008

To investigate the change of taste sensitivity which follows after treatment for xerostomia, from September, 2006 to July, 2007, we categorized the patients, who were diagnosed as xerostomia in Oral Medicine, College of Dentistry, Busan National University, as subject group and from September, 2007 to December. The patients who were not diagnosed as systemic disease were categorized as control group. The results were as follows ; 1. Taste threshold comparison showed the differences at tongue lateral, tongue tip, circumvallate papilla between subject and control. 2. Taste threshold comparison showed no difference in male between subject and control. 3. Taste threshold comparison showed decrease in whole tongue except soft palate in female. 4. Taste threshold comparison showed no difference between first and second visit, but there was a tendency to change in circumvallate papilla.

• Journal of dental hygiene science
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• 제12권2호
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• pp.171-179
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• 2012

The aim of this study was to analyze the factors related to whole saliva flow and the xerostomia for the ground use of the materials in developing oral health improvement program and life quality improvement program. So, this study performed a questionnaire survey, targeting at 160 adults, older than 40 years, living in Gyeonggi and Incheon provinces from January to February 2011 and measured unstimulated salivary flow rate and stimulated salivary flow rate. The results are as followings. The group of participants who took gums and candies to relieve oral dryness had low stimulated whole saliva flow. The group of participants who graduated from middle schools, who separated by death, who were not healthy with menopause, and who recognized periodontal disease symptoms and tongue burning sensation recognized more symptoms of dry mouth than others. In addition, the group of participants who were not satisfied with life so much, who couldn't feel the meaning of life, and who recognized negative feelings frequently recognized symptoms of dry mouth more. Women, the group of participants who graduated from middle schools, who suffered from depressive symptoms, and who recognized halitosis had low unstimulated whole saliva flow. The group of participants who graduated from middle schools, who were not satisfied with life so much, who couldn't feel the meaning of life, and who were not satisfied with themselves had low stimulated saliva flow.

• Journal of the Korea Convergence Society
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• 제10권12호
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• pp.437-445
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• 2019

This study is a 1:1 survey of 154 elderly 65 or older to find out the direct and indirect effects of oral dryness on their quality of life through the medium of depression. As a result, the subjective oral health of the elderly and oral dryness, depression and quality of life were correlated. In the medial effect of subjective oral health and oral dryness on the quality of life, subjective oral health is the quality of life(β=.23, p<.01), depression(β=-.24, p<.01)and the influence of subjective oral health when depression is controlled(β=.08, p>05) was not significant and was completely mediated. Oral dryness is the quality of life(β=-.24, p<.01) and depression(β=.37, p<.001) was shown to have a significant effect and the influence of oral dryness when depression is controlled(β=.00, p>.05) was not significant and was completely mediated. In order to improve the quality of life for the elderly, it is necessary to develop and apply a comprehensive arbitration program that can improve oral health and oral function, and to study the effects of consequences in the future.

• Journal of dental hygiene science
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• 제12권6호
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• pp.624-633
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• 2012

This study was executed to provide the basic data that can be helpful for a program aiming at the enhancement of life quality or establishment of policy related to public health by analyzing the importance of health state among the middle-aged adults when it came to the decision of life quality. For 160 adults who were older than 40 years old, a survey was conducted and the results were derived by using t-test, one way ANOVA, and multiple regression analysis. Followings are the outcome of the study. According to such results, it was known that the level of general life quality and oral health related life quality were shown to be different depending on symptoms of depression and xerostomia. Therefore, it suggests that prevention and early intervention of depression and xerostomia will make a great contribution to improve the life quality among the middle-aged adults.

• Journal of Oral Medicine and Pain
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• 제37권2호
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• pp.107-112
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• 2012

Orofacial movement disorders (OMD) are uncontrolled movement of the muscles involving the face, tongue, lip and mandible. Due to variable oral and lingual muscles affected, the patients with OMD are interfered with the appropriate performance such as chewing, swallowing and talking. In this study, there are 4 OMD cases with oral dryness that saliva flow rate is decreased or not. The symptoms are improved after oral administration of pilocarpine to 4 patients with OMD. Therefore, we suggest that objective or subjective oral dryness could be etiologic factor in OMD and pilocarpine could be regarded as medication for OMD.

• Journal of the Korea Academia-Industrial cooperation Society
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• 제13권10호
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• pp.4604-4611
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• 2012

The purpose of the research is to investigate the factors affecting the life quality of oral health according to the knowledge and behavior related with oral health. Total 272 people who work in Gyeong-Nam province participated in this survey. The research shows that major 4 factors are subjective whole body health, ages, dietary pattern and dry mouse. The subjective whole body health and dietary pattern have an positive effect on the life quality of oral health, whereas ages and dry mouse an negative effect on this. As a result, the health and the life quality of oral health should be improved by investigating the factors affecting oral health and thus developing the program enhancing the oral health to prevent oral disease.